Obstetrics and gynecology最新文献

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Navigating the Legal Landscape of Reproductive Rights and Medical Training After LePage v. Mobile Infirmary Clinic. LePage 诉 Mobile Infirmary Clinic 案之后,生殖权利和医疗培训的法律前景。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-12 DOI: 10.1097/AOG.0000000000005728
Alexandra Herweck, Ariana M Traub, Lisa M Shandley
{"title":"Navigating the Legal Landscape of Reproductive Rights and Medical Training After LePage v. Mobile Infirmary Clinic.","authors":"Alexandra Herweck, Ariana M Traub, Lisa M Shandley","doi":"10.1097/AOG.0000000000005728","DOIUrl":"https://doi.org/10.1097/AOG.0000000000005728","url":null,"abstract":"","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compliance Rate With Triage Test and Treatment for Participants Screening Positive in Cervical Cancer Screening Programs: A Systematic Review and Meta-analysis. 宫颈癌筛查计划中筛查阳性参与者的分诊测试和治疗依从率:系统回顾与元分析》。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-12 DOI: 10.1097/AOG.0000000000005723
Minmin Wang, Mailikezhati Maimaitiming, Yanxin Bi, Yinzi Jin
{"title":"Compliance Rate With Triage Test and Treatment for Participants Screening Positive in Cervical Cancer Screening Programs: A Systematic Review and Meta-analysis.","authors":"Minmin Wang, Mailikezhati Maimaitiming, Yanxin Bi, Yinzi Jin","doi":"10.1097/AOG.0000000000005723","DOIUrl":"https://doi.org/10.1097/AOG.0000000000005723","url":null,"abstract":"<p><strong>Objective: </strong>To assess the rates of adherence to triage testing after positive screening results and referral to treatment for precancerous lesions in global cervical cancer screening programs.</p><p><strong>Data sources: </strong>We searched three electronic databases (Medline, EMBASE, and Web of Science) for articles published in the English language from January 1, 2018, to December 31, 2023. We included studies reporting the compliance rate of triage testing and precancer treatment in cervical cancer screening programs. ClinicalTrials.gov was reviewed, and no more studies were identified.</p><p><strong>Methods of study selection: </strong>The combined search strategies identified 1,673 titles, of which 858 titles and abstracts were screened and 113 full-text articles were assessed for eligibility. A total of 33 studies met the inclusion criteria and were included in the meta-analysis.</p><p><strong>Tabulation, integration, and results: </strong>Thirty-three studies were included in the systematic review and meta-analysis. The average compliance rate for women screening positive was 77.1% for triage testing and 69.4% for referral to treatment. Compliance varied by country income level, screening guideline approach, and target population.</p><p><strong>Conclusion: </strong>The current compliance rate was lower than the 90% target set by the World Health Organization's global strategy to eliminate cervical cancer. Inadequate follow-up of participants screening positive revealed a gap between the screening program and clinical care.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rh D Immune Globulin Administration After Abortion or Pregnancy Loss at Less Than 12 Weeks of Gestation. 妊娠不足 12 周的流产或妊娠失败后注射 Rh D 免疫球蛋白。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-10 DOI: 10.1097/AOG.0000000000005733
{"title":"Rh D Immune Globulin Administration After Abortion or Pregnancy Loss at Less Than 12 Weeks of Gestation.","authors":"","doi":"10.1097/AOG.0000000000005733","DOIUrl":"https://doi.org/10.1097/AOG.0000000000005733","url":null,"abstract":"<p><p>This Clinical Practice Update provides revised guidance on Rh testing and Rh D immune globulin administration for individuals undergoing abortion or experiencing pregnancy loss at less than 12 0/7 weeks of gestation. This document updates Practice Bulletin No. 225, Medication Abortion Up to 70 Days of Gestation (Obstet Gynecol 2020;136:e31-47); Practice Bulletin No. 200, Early Pregnancy Loss (Obstet Gynecol 2018;132:e197-207); and Practice Bulletin No. 181, Prevention of Rh D Alloimmunization (Obstet Gynecol 2017;130:e57-70).</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Panniculus Retractor Use for Visualization of Fetal Anatomy: A Randomized Controlled Trial. 使用环形牵引器观察胎儿解剖:随机对照试验
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1097/AOG.0000000000005689
Melissa L Wise, Marvin Okon, Katelyn N Pratt, Andrew S Lane, Laura M Carlson, Kacey Y Eichelberger, Amy H Crockett, Lu Zhang, Daniel N Pasko
{"title":"Panniculus Retractor Use for Visualization of Fetal Anatomy: A Randomized Controlled Trial.","authors":"Melissa L Wise, Marvin Okon, Katelyn N Pratt, Andrew S Lane, Laura M Carlson, Kacey Y Eichelberger, Amy H Crockett, Lu Zhang, Daniel N Pasko","doi":"10.1097/AOG.0000000000005689","DOIUrl":"10.1097/AOG.0000000000005689","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether use of a panniculus retractor device for pregnant patients with body mass index (BMI) 40 or higher and a panniculus improves the completion rate of the fetal anatomic examination.</p><p><strong>Methods: </strong>This was a randomized trial in which eligible patients with BMI 40 or higher and a panniculus were randomized to undergo their detailed fetal anatomic examination with a panniculus retractor device in place compared with usual care. The primary outcome was the completion rate of 16 prespecified views from the anatomic examination. Secondary outcomes included completion rate of all 64 views from our institution's detailed anatomic examination, duration of examination, major fetal anomaly detection rate, depth from the skin to amniotic cavity before and after retractor placement, patient and ultrasonographer satisfaction, and prespecified adverse events. We assumed a baseline completion rate of 23% for the primary outcome and targeted a twofold improvement with 80% power and two-sided α of 0.05, which resulted in a sample size of 132 participants. The goal enrollment was increased to 150 participants to account for potential dropout. Statistical tests included the Student's t test, χ 2 , and relative risks (RRs) as appropriate.</p><p><strong>Results: </strong>From March to July of 2023, 150 participants completed the study: 74 in the retractor group and 76 in the usual care group. Baseline characteristics were similar between groups except for panniculus grade. The completion rate of 16 prespecified views was 25.7% (19/74) in the retractor group and 31.6% (24/76) in the control group (RR 0.81, 95% CI, 0.49-1.35). There were no significant differences between groups for any of the secondary outcomes. Patient satisfaction and ultrasonographer satisfaction were similar between groups.</p><p><strong>Conclusion: </strong>Use of a panniculus retractor device during the fetal anatomic examination for patients with BMI 40 or higher and a panniculus was well tolerated by patients and ultrasonographers but did not improve the completion rate of 16 prespecified fetal anatomic views.</p><p><strong>Clinical trial registration: </strong>ClinicalTrials.gov , NCT05764408.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141760105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal Remote Blood Pressure Monitoring. 围产期远程血压监测。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1097/AOG.0000000000005690
Adam K Lewkowitz, Alisse Hauspurg
{"title":"Perinatal Remote Blood Pressure Monitoring.","authors":"Adam K Lewkowitz, Alisse Hauspurg","doi":"10.1097/AOG.0000000000005690","DOIUrl":"10.1097/AOG.0000000000005690","url":null,"abstract":"<p><p>Perinatal mortality and severe maternal morbidity among individuals with hypertensive disorders of pregnancy (HDP) are often driven by persistent, uncontrolled hypertension. Whereas traditional perinatal blood pressure (BP) ascertainment occurs through in-person clinic appointments, self-measured blood pressure (SMBP) programs allow individuals to measure their BP remotely and receive remote management by a medical team. Though data remain limited on clinically important outcomes such as maternal morbidity, these programs have shown promise in improving BP ascertainment rates in the immediate postpartum period and enhancing racial and ethnic equity in BP ascertainment after hospital discharge. In this narrative review, we provide an overview of perinatal SMBP programs that have been described in the literature and the data that support their efficacy. Furthermore, we offer suggestions for practitioners, institutions, and health systems that may be considering implementing SMBP programs, including important health equity concerns to be considered. Last, we discuss opportunities for ongoing and future research regarding SMBP programs' effects on maternal morbidity, long-term health outcomes, inequities that are known to exist in HDP and HDP-related outcomes, and the cost effectiveness of these programs.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141760152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated Blood Pressure in Pregnancy and Long-Term Cardiometabolic Health Outcomes. 妊娠期血压升高与长期心脏代谢健康结果。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1097/AOG.0000000000005674
Christine Field, William A Grobman, Jiqiang Wu, Alan Kuang, Denise M Scholtens, William L Lowe, Nilay S Shah, Sadiya S Khan, Kartik K Venkatesh
{"title":"Elevated Blood Pressure in Pregnancy and Long-Term Cardiometabolic Health Outcomes.","authors":"Christine Field, William A Grobman, Jiqiang Wu, Alan Kuang, Denise M Scholtens, William L Lowe, Nilay S Shah, Sadiya S Khan, Kartik K Venkatesh","doi":"10.1097/AOG.0000000000005674","DOIUrl":"10.1097/AOG.0000000000005674","url":null,"abstract":"<p><strong>Objective: </strong>To examine the association between elevated blood pressure (BP) in the early third trimester and cardiometabolic health 10-14 years after delivery.</p><p><strong>Methods: </strong>This is a secondary analysis from the prospective HAPO FUS (Hyperglycemia and Adverse Pregnancy Outcome Follow-Up Study). Blood pressure in the early third trimester was categorized per American College of Cardiology/American Heart Association thresholds for: normal BP below 120/80 mm Hg (reference), elevated BP 120-129/below 80 mm Hg, stage 1 hypertension 130-139/80-89 mm Hg, and stage 2 hypertension 140/90 mm Hg or higher. Cardiometabolic outcomes assessed 10-14 years after the index pregnancy were type 2 diabetes mellitus and measures of dyslipidemia, including low-density lipoprotein (LDL) cholesterol 130 mg/dL or higher, total cholesterol 200 mg/dL or higher, high-density lipoprotein (HDL) cholesterol 40 mg/dL or lower, and triglycerides 200 mg/dL or higher. Adjusted analysis was performed with the following covariates: study field center, follow-up duration, age, body mass index (BMI), height, family history of hypertension and diabetes, smoking and alcohol use, parity, and oral glucose tolerance test glucose z score.</p><p><strong>Results: </strong>Among 4,692 pregnant individuals at a median gestational age of 27.9 weeks (interquartile range 26.6-28.9 weeks), 8.5% (n=399) had elevated BP, 14.9% (n=701) had stage 1 hypertension, and 6.4% (n=302) had stage 2 hypertension. At a median follow-up of 11.6 years, among individuals with elevated BP, there was a higher frequency of diabetes (elevated BP: adjusted relative risk [aRR] 1.88, 95% CI, 1.06-3.35; stage 1 hypertension: aRR 2.58, 95% CI, 1.62-4.10; stage 2 hypertension: aRR 2.83, 95% CI, 1.65-4.95) compared with those with normal BP. Among individuals with elevated BP, there was a higher frequency of elevated LDL cholesterol (elevated BP: aRR 1.27, 95% CI, 1.03-1.57; stage 1 hypertension: aRR 1.22, 95% CI, 1.02-1.45, and stage 2 hypertension: aRR 1.38, 95% CI, 1.10-1.74), elevated total cholesterol (elevated BP: aRR 1.27, 95% CI, 1.07-1.52; stage 1 hypertension: aRR 1.16, 95% CI, 1.00-1.35; stage 2 hypertension: aRR 1.41 95% CI, 1.16-1.71), and elevated triglycerides (elevated BP: aRR 2.24, 95% CI, 1.42-3.53; stage 1 hypertension: aRR 2.15, 95% CI, 1.46-3.17; stage 2 hypertension: aRR 3.24, 95% CI, 2.05-5.11) but not of low HDL cholesterol.</p><p><strong>Conclusion: </strong>The frequency of adverse cardiometabolic outcomes at 10-14 years after delivery was progressively higher among pregnant individuals with BP greater than 120/80 in the early third trimester.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and Management of Cervical Squamous Intraepithelial Lesions in Pregnancy and Postpartum. 妊娠期和产后宫颈鳞状上皮内病变的诊断和处理。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-03-29 DOI: 10.1097/AOG.0000000000005566
Alyssa Larish, Margaret E Long
{"title":"Diagnosis and Management of Cervical Squamous Intraepithelial Lesions in Pregnancy and Postpartum.","authors":"Alyssa Larish, Margaret E Long","doi":"10.1097/AOG.0000000000005566","DOIUrl":"10.1097/AOG.0000000000005566","url":null,"abstract":"<p><p>Perinatal care provides important health care opportunities for many individuals at risk for cervical cancer. Pregnancy does not alter cervical cancer screening regimens. ASCCP risk-based management has a colposcopy threshold of a 4% immediate risk of cervical intraepithelial neoplasia (CIN) 3 or cancer, but the actual risk can be considerably higher based on current and past screening results. Improving cervical cancer outcomes with diagnosis during pregnancy rather than postpartum and facilitating further evaluation and treatment postpartum for lesser lesions are the perinatal management goals. Although colposcopy indications are unchanged in pregnancy, some individuals with lower risk of CIN 2-3 and reliable access to postpartum evaluation may defer colposcopy until after delivery. Cervical intraepithelial neoplasia diagnosed in pregnancy tends to be stable, with frequent regression postpartum, though this is not universal. Colposcopic inspection during pregnancy can be challenging. Although biopsies in pregnancy are subjectively associated with increased bleeding, they do not increase complications. Endocervical curettage and expedited treatment are unacceptable. Treatment of CIN 2-3 in pregnancy is not recommended. Excisional biopsies in pregnancy are reserved for suspicion of malignancy that cannot be confirmed by colposcopic biopsy and when excisional biopsy results would alter oncologic or pregnancy care. Surveillance of high-grade lesions in pregnancy uses human papillomavirus-based testing, cytology, and colposcopy, with biopsy of worsening lesions every 12-24 weeks from diagnosis until postpartum evaluation. Mode of delivery does not definitively affect persistence of CIN postpartum. Postpartum care may involve a full colposcopic evaluation or expedited excisional procedure if indicated.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140318781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylactic Radiologic Interventions for Postpartum Hemorrhage Control in Women With Placenta Accreta Spectrum Disorder: A Systematic Review and Meta-analysis. 对胎盘早剥谱系障碍产妇进行预防性放射干预以控制产后出血:系统回顾与元分析》。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-02 DOI: 10.1097/AOG.0000000000005662
Lisanne R Bonsen, Kosma Sleijpen, Joris Hendriks, Thijs A J Urlings, Olaf M Dekkers, Saskia le Cessie, Marc van de Velde, Pema Gurung, Thomas van den Akker, Johanna G van der Bom, Dacia D C A Henriquez
{"title":"Prophylactic Radiologic Interventions for Postpartum Hemorrhage Control in Women With Placenta Accreta Spectrum Disorder: A Systematic Review and Meta-analysis.","authors":"Lisanne R Bonsen, Kosma Sleijpen, Joris Hendriks, Thijs A J Urlings, Olaf M Dekkers, Saskia le Cessie, Marc van de Velde, Pema Gurung, Thomas van den Akker, Johanna G van der Bom, Dacia D C A Henriquez","doi":"10.1097/AOG.0000000000005662","DOIUrl":"10.1097/AOG.0000000000005662","url":null,"abstract":"<p><strong>Objective: </strong>To quantify the association between prophylactic radiologic interventions and perioperative blood loss during cesarean delivery in women with placenta accreta spectrum disorder through a systematic review and network meta-analysis.</p><p><strong>Data sources: </strong>On January 3, 2023, a literature search was conducted in PubMed, EMBASE, Cochrane Library, and Web of Science. We also checked ClinicalTrials.gov retrospectively. Prophylactic radiologic interventions to reduce bleeding during cesarean delivery involved preoperative placement of balloon catheters, distal (internal or common iliac arteries) or proximal (abdominal aorta), or sheaths (uterine arteries). The primary outcome was volume of blood loss; secondary outcomes were the number of red blood cell units transfused and adverse events. Studies including women who received an emergency cesarean delivery were excluded.</p><p><strong>Methods of study selection: </strong>Two authors independently screened citations for relevance, extracted data, and assessed the risk of bias of individual studies with the Cochrane Risk of Bias in Non-randomized Studies of Interventions tool.</p><p><strong>Tabultation, integration, and results: </strong>From a total of 1,332 screened studies, 50 were included in the final analysis, comprising 5,962 women. These studies consisted of two randomized controlled trials and 48 observational studies. Thirty studies compared distal balloon occlusion with a control group, with a mean difference in blood loss of -406 mL (95% CI, -645 to -167). Fourteen studies compared proximal balloon occlusion with a control group, with a mean difference of -1,041 mL (95% CI, -1,371 to -710). Sensitivity analysis excluding studies with serious or critical risk of bias provided similar results. Five studies compared uterine artery embolization with a control group, all with serious or critical risk of bias; the mean difference was -936 mL (95% CI, -1,522 to -350). Reported information on adverse events was limited.</p><p><strong>Conclusion: </strong>Although the predominance of observational studies in the included literature warrants caution in interpreting the findings of this meta-analysis, our findings suggest that prophylactic placement of balloon catheters or sheaths before planned cesarean delivery in women with placenta accreta spectrum disorder may, in some cases, substantially reduce perioperative blood loss. Further study is required to quantify the efficacy according to various severities of placenta accreta spectrum disorder and the associated safety of these radiologic interventions.</p><p><strong>Systematic review registration: </strong>PROSPERO, CRD42022320922.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11321610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duration of Induction of Labor for Second-Trimester Medication Abortion and Adverse Outcomes. 第二胎药物流产的引产持续时间与不良后果。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-07-11 DOI: 10.1097/AOG.0000000000005663
Ashish Premkumar, Vanya Manthena, Jocelyn Wascher, Eryn K Wanyonyi, Camille Johnson, Lahari Vuppaladhadiam, Julie Chor, Beth A Plunkett, Isa Ryan, Olivert Mbah, Jungeun Lee, Emily Barker, Laura Laursen, Leanne R McCloskey, Sloane L York
{"title":"Duration of Induction of Labor for Second-Trimester Medication Abortion and Adverse Outcomes.","authors":"Ashish Premkumar, Vanya Manthena, Jocelyn Wascher, Eryn K Wanyonyi, Camille Johnson, Lahari Vuppaladhadiam, Julie Chor, Beth A Plunkett, Isa Ryan, Olivert Mbah, Jungeun Lee, Emily Barker, Laura Laursen, Leanne R McCloskey, Sloane L York","doi":"10.1097/AOG.0000000000005663","DOIUrl":"10.1097/AOG.0000000000005663","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between duration of labor during second-trimester medication abortion and adverse outcomes.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study including all individuals with a singleton gestation undergoing second-trimester medication abortion without evidence of advanced cervical dilation, rupture of membranes, or preterm labor at four centers. The primary exposure was duration of labor (ie, hours spent from receiving misoprostol to fetal expulsion). The primary outcome was composite morbidity , defined as uterine rupture, need for blood transfusion, clinical chorioamnionitis, intensive care unit admission, or need for readmission. We performed bivariate and multivariate negative binomial analyses. A post hoc subgroup analysis was performed to assess for the risk of the primary outcome by gestational age. We performed tests of homogeneity based on history of uterine scarring and parity.</p><p><strong>Results: </strong>Six hundred eighty-one individuals were included. The median duration of labor was 11 hours (interquartile range 8-17 hours). One hundred thirty-one (19.2%) experienced the primary outcome. When duration of labor was evaluated continuously, a longer duration of labor was associated with an increased frequency of morbidity (adjusted β=0.68, 95% CI, 0.32-1.04). When duration of labor was evaluated categorically, those experiencing the highest quartile of duration (ie, 17 hours or more) had a statistically higher risk for experiencing morbidity compared with individuals in all other quartiles (adjusted relative risk 1.99, 95% CI, 1.34-2.96). When we focused on components of the composite outcome, clinical chorioamnionitis was significantly different between those experiencing a longer duration and those experiencing a shorter duration of labor (26.2% vs 10.6%, P <.001). On subgroup analysis, gestational age was not associated with the risk of composite morbidity. Tests of homogeneity demonstrated no significant difference in the risk for morbidity among individuals with a history of uterine scarring or based on parity.</p><p><strong>Conclusion: </strong>Duration of labor was independently associated with risks for adverse maternal outcomes during second-trimester medication abortion, specifically clinical chorioamnionitis.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient Preferences for Immediate Compared With Delayed Postpartum Intrauterine Device Placement. 患者对产后立即放置宫内节育器与延迟放置宫内节育器的偏好。
IF 5.7 2区 医学
Obstetrics and gynecology Pub Date : 2024-09-01 Epub Date: 2024-06-18 DOI: 10.1097/AOG.0000000000005647
Theresa Christensen, Susanna Ostrowski, Arden McAllister, Blythe Bynum, Marilyn M Schapira, Sarita Sonalkar
{"title":"Patient Preferences for Immediate Compared With Delayed Postpartum Intrauterine Device Placement.","authors":"Theresa Christensen, Susanna Ostrowski, Arden McAllister, Blythe Bynum, Marilyn M Schapira, Sarita Sonalkar","doi":"10.1097/AOG.0000000000005647","DOIUrl":"10.1097/AOG.0000000000005647","url":null,"abstract":"<p><strong>Objective: </strong>To use choice-based conjoint survey methodology to evaluate patient values and decision making regarding immediate compared with delayed placement of postpartum intrauterine devices (IUDs).</p><p><strong>Methods: </strong>We conducted a cross-sectional study in which we surveyed 200 nonpregnant, parous patients. Participants chose between hypothetical postpartum IUDs varying in multiple attributes (hormonal or nonhormonal IUD type, placement timing, 1-year efficacy, expulsion risk, risk of lost strings, and malposition risk). The primary outcome was preference for immediate compared with delayed postpartum IUD placement and importance of placement timing relative to other attributes. Secondarily, we evaluated whether demographic and neighborhood characteristics were associated with timing preference and attribute importance.</p><p><strong>Results: </strong>We included 190 participants for analysis. Most participants (62.6%) preferred delayed placement. There was no significant difference in timing preference by race ( P =.28) or block-level Area Deprivation Index score ( P =.27). Patients who preferred immediate placement were more likely to have public insurance than private insurance (70.4% vs 29.6%, P =.04); however, the majority of patients (55.1%) with public insurance still preferred delayed placement. Attributes of IUD type, malposition risk, 1-year efficacy, and expulsion risk all had greater effects on patient decision making than placement timing. There was no difference in attribute importance by race ( P =.30), Area Deprivation Index score ( P =.88), or insurance type ( P =.22).</p><p><strong>Conclusion: </strong>Patients preferred the higher efficacy and lower complication rates of delayed postpartum IUD placement over the convenience of immediate placement. Insurance considerations may affect these timing preferences. There was no difference in attribute importance between demographic groups or based on neighborhood-level factors, indicating that, although both immediate and delayed postpartum IUD placement should be offered, counseling should not vary according to individual demographic characteristics.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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