Odesa National University Herald. Chemistry最新文献

{"title":"THE DIRHENIUM(III) COMPLEX COMPOUNDS WITH IMIDAZOLE AND BENZIMIDAZOLE","authors":"O. Velychko, O. Golichenko, O. Shtemenko","doi":"10.18524/2304-0947.2019.3(71).177731","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177731","url":null,"abstract":"Imidazole and it’s derivatives are structural fragments of certain enzymes, aminoacids, alkaloids and drugs. To date, the participation of imidazole in human metabolism, especially in the biosynthesis of natural purine bases of RNA and DNA, has been proven. Benzimidazole is one of the most used compound in medical chemistry. The various derivatives of substances, that exhibit analgesic, antidiabetic, anti-inflammatory, antitumor and antiviral activities were synthesized based on benzimidazole. This fact paves the way for the synthesis of antimetabolites, which can delay biosynthesis during biotransformation and inhibit the growth of malignant tumors. Thus, in the present work, the interaction of complex compounds with a single cluster fragment of Re 2 6+ (NBu 4 ) 2 Re 2 Cl 8 and trans-tetrachlorodi-μ-alkylcarboxylates of dirhenium(III) with representatives of the azole class – imidazole and benzimidazole was studied under various conditions. As a result of the experiments, methods for the synthesis of cis-[Re 2 (X) 4 Cl 4 (CH 3 CN) 2 ]Cl 2 (X is imidazole, benzimidazole) in an electron-donating organic solvent – CH3CN under heating in an inert atmosphere were developed. The starting materials were (NBu4)2Re2Cl8 and the selected azoles at a molar ratio of 1:10. The yield of the target compounds was 67-75%. We also investigated the reaction between trans-tetrachloridi-μ-alkylcarboxylates of dirhenium(III) and indicated azoles in a non-donor solvent (1,2-dichloroethane) in inert atmosphere at a molar ratio of reactants of 1:20. As a result of the interaction, complex compounds of the general formula (XH) 2 Re 2 Cl 8 (X – imidazole, benzimidazole) are formed, in which azoles are cations. The yield of reaction products was 83-87%. All target substances are synthesized, isolated in individual state, their spectral properties are investigated. The composition and structure of the obtained complex compounds were confirmed by IR- and NMR- spectroscopy on 1H and 13C, conductometry, and electronic absorption spectroscopy.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"842 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75507785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SYNTHESIS OF FLUORINE-CONTAINING ANALOGS OF PROCAINAMIDE","authors":"I. I. Gaidarzhy, L. A. Motnyak, I. Kravchenko","doi":"10.18524/2304-0947.2019.3(71).177733","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177733","url":null,"abstract":"","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88980055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LUMINESCENT DETERMINATION OF FERULIC ACID IN GRAPES WINE","authors":"S. V. Bel’tyukova, O. Teslyuk, E. Liventsova","doi":"10.18524/2304-0947.2019.3(71).177741","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177741","url":null,"abstract":"The luminescent properties of important phenolic compounds – ferulic acid (FA), which is a quality marker of grape wines, were studied. It has been established that in thin layer of sorbent, FA has an intense intrinsic luminescence enhanced in the presence of yttrium (III) ions and a non-ionic surfactant Neonol 9-12. Optimal conditions for the sorbate complexation were found. The influence of yttrium (III) chloride ions concentration in solution, the acidity of the medium, surface-active and donor-active substances on the luminescence intensity of the sorbates complexes were studied. The maximum increase of I lum complex (2.5 times) in phase of sorbent is achieved in the micellar medium surfactant Neonol 9-12. The optimal conditions for chromatographic isolation of ferulic acid were found. The maximum increase of luminescence intensity was obtained on chromatographic plate Merck TLC Aluminum Plates. The n-butanol-acetic acid-water system (4: 1: 2) was chosen as the mobile phase. The yttrium (III) chloride in presence surfactant Neonol 9-12 was proposed as an enhanced solution. A 4% aqueous hexamine solution was used to achieve the optimal pH value (6,5-6,9) . The response factor of FA in this conditions was Rf = 0.52. The method of solid-phase luminescent determination of ferulic acid in wines of different manufacturers has been developed on the base of conducted research. FA content in wines were determined as per calibration curve, while registering I lum. of sorbates complexes yttrium (III) chloride with FA at λ=485 nm (λ exit = 365 nm). Correctness of results obtained was checked by the “entered-found” method. The determination accuracy and reliability was verified by statistical processing of the findings obtained. The relative standard deviation is (S r ) 4,5 – 7,8%. The FA detection limit was 0.03 µg/ml.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87162406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ACID-BASE EQUILIBRIA IN SOLUTIONS OF NEW 4-HYDROXYSTYRYL DYES BASED ON 1-OCTILPIRIDINIUM","authors":"A. Chebotarev, Y. Zhukova, Y. Studenyak, D. Snigur","doi":"10.18524/2304-0947.2019.3(71).177732","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177732","url":null,"abstract":"In this paper, the acid-base properties of a number of new 4-hydroxystyryl dyes based on 1-octylpyridinium in solutions have been studied by tristimulus colorimetry and spectrophotometry. The studied dyes are obtained by the interaction of equivalent amounts of corresponding heterocyclic methylene bases salts with 4-hydroxyaldehydes in acetonitrile. The advantages of the tristimulus colorimetric method in the study of acid-base equilibria in dyes solutions were noted. It was shown that the use of data on the change in the values of colorimetric functions (specific color discrimination), depending on the medium acidity allows us to determine the constants of ionization of the functional groups of 4-hydroxystyryl dyes. It was shown that the quantitative description of the color of objects of different nature by calculating their color coordinates on the basis of spectrophotometric data allows obtaining information about their state in solutions. Using the values of the colorimetric functions of the ionic-molecular forms of 4-hydroxystyryl dyes as an analytical signal allows us to obtain a coherent picture of existing acid-base equilibria in a wide range of the medium acidity. Based on the obtained experimental data, a probable scheme of acid-base equilibrium in aqueous solutions of 4-hydroxystyryl dyes was proposed. It was shown that in the acidic medium 4-hydroxystyryl dyes exist in a protonated single-charged cationic form, and with pH rise dissociation of phenolic hydroxyl and tautomerization with the formation of a merocyanine form occurs. The corresponding diagrams for the distribution of ion-molecular forms of 4-hydroxystyryl dyes have been constructed, depending on the acidity of the medium.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"169 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74103339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FIBROUS CHEMISORBENT-AMFOLITE BASED ON THE COMPLEX COMPOUNDS OF NICKEL (II) CHLORIDE AND ETHYLENEDIAMINE","authors":"A. Ennan, R. Khoma, R. M. Dlubovskiy, N. Abramova, T. Mikhaylova","doi":"10.18524/2304-0947.2019.3(71).177739","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177739","url":null,"abstract":"","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79828506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIRECTED SYNTHESIS OF MIXED-LIGAND-HETEROMETALLIC XYLARATOGERMANATES OF Co(II) WITH 1,10-PHENANTHROLINE / 2,2'-BIPYRIDINE","authors":"E. Chebanenko, I. Seifullina, E. Martsinko","doi":"10.18524/2304-0947.2019.3(71).177725","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.3(71).177725","url":null,"abstract":"Coordination compounds with complex cations of Co 2+ with 1,10-phenanthroline, 2,2’-bipyridine and tetrameric xylaratogermanate anion were obtained. Their composition and structure were established by the methods of elemental analysis, IR-spectroscopy and thermogravimetric analysis. In the IR-spectrum of I , II bands of asymmetric υas(COO–) (~1686 cm -1 ) and symmetric υs(COO–) (~ 1442 cm -1 ) valence vibrations of carboxylate groups are presented. The presence of υ(C-O) (~ 1069 cm -1 ) band (alcoholic type) and d(C-OH) (~1144 cm -1 ) band, which is typical for the xylaric acid, indicates that not all hydroxyl groupsof the H 5 Xylar ligand are deprotonated. Absorption bands υ(Ge-O) (~737 cm -1 ), υ as (GeOGe) (~851 cm-1) are also detected. They indicate the binding of germanium to xylaric acid and formation of the Ge-O-Ge bridge. The deformation vibration band of the Ge-О-Н (~821 cm -1 ) indicates the implementation of the hydrolyzed form of germanium. There also appear n(ОН)H 2 O, ns(C–Harom.), ν(C-Carom.), n(C-Narom.), δ(С-H) bands, that are typical for crystallization water molecules and 1,10-phenanthroline ( I ), 2,2’-bipyridine ( II ). The thermal destructions of the both compounds are similar. On the thermograms of both compounds one low-temperature effect is presented at 80-270 °С(for I ) and 80-260 °С (for II ) respectively. According to the temperature of elimination and the weight loss (8,75% for I and 14,5% for II ), crystallization water molecules were calculated ( I – 12, II – 20). Due to the mass loss along the thermogravimetric curve at 900 °C, the final products of thermal destruction is a mixture of CoO + GeO 2 . The molecular formulas of complexes I , II are proposed in the accordance of the results of elemental analysis, IR spectroscopy and thermogravimetric analysis: [Сo(phen) 3 ] 2 [(OH) 2 Ge 2 (m-HXylar) 4 Ge 2 (m-OH) 2 ]∙12Н 2 О ( I ), [Сo(bipy) 3 ] 2 [(OH) 2 Ge 2 (m-HXylar) 4 Ge 2 (m-OH) 2 ]∙20Н 2 О ( II ). Their scheme of structure were suggested.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73370935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NEW LUMINESCENT PROBE BASED ON EUROPIUM (III) COMPLEX FOR DETERMINATION OF CURCUMIN","authors":"O. Malynka, М. Е. Vielts, А. Yegorova, Yuliya V Scrypynets, V. Antonovich","doi":"10.18524/2304-0947.2019.2(70).169237","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.2(70).169237","url":null,"abstract":"","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77910458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STUDY OF INTERACTION OF FABOMOTIZOLE DIHYDROCHLORIDE WITH HUMAN SERUM ALBUMIN BY FLUORESCENT METHOD","authors":"A. Yegorova, G. Maltsev, Y. Scrypynets, S. Kashutskуy, V. Antonovich","doi":"10.18524/2304-0947.2019.2(70).169223","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.2(70).169223","url":null,"abstract":"","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74202734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFECT OF DURATION OF THE BENTONITE ACID MODIFICATION ON THE ACTIVITY OF PD(II)-CU(II) CATALYTIC COMPOSITIONS IN THE REACTION OF CARBON MONOXIDE OXIDATION","authors":"G. Dzhyga","doi":"10.18524/2304-0947.2019.2(70).169238","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.2(70).169238","url":null,"abstract":"The effect of duration of the bentonite acid modification on its physicochemical and structural parameters and also on the catalytic properties of bentonite anchored palladium-copper complexes in the reaction of low-temperature carbon monoxide oxidation with air oxygen has been studied. For all acid modified bentonite samples, 1H-Bent-τ (τ = 0.5, 1.0, 3.0, 4.0, and 6.0 h), some regularities of changes as compared with natural bentonite, N-Bent, in the bentonite phase composition and X-ray spectral parameters of montmorillonite that is a samples, regardless a contact time, τ, the montmorillonite crystalline structure does not change however its aluminosilicate layers constrict for both bentonite acid modified samples and Pd(II)-Cu(II)/1H-Bent-τ compositions. After acid treatment, the number and positions of IR bands characterizing structural groups Al-Al-OH, Al-Fe 3+ -OH, Si-O-Si, and Si-O-Al of Mont phase do not change however their intensities, except for Si-O-Si, decrease pointing to the loss of Al 3+ and Fe 3+ cations. Palladium-copper complexes can be anchored not only on Mont structural groups but also on surfaces of quarts, amorphous SiO 2 , and calcite if any. It has been found that the changes in physicochemical and structural parameters of the bentonite samples result in alterations in the catalytic activity of Pd(II)-Cu(II)/S— compositions (S— is N-Bent or 1H-Bent-τ) in the reaction of carbon monoxide oxidation with air oxygen. The composition based on 1Н-Бент-0.5 characterizing by the minimum pH value of its aqueous suspension shows the maximum catalytic activity: CO conversion is 78 %.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73987029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTERACTION OF THE LANTHANA, YTTRIA WITH ITERBIY AT TEMPERATURE 1100 °C","authors":"O. Chudinovych","doi":"10.18524/2304-0947.2019.2(70).169235","DOIUrl":"https://doi.org/10.18524/2304-0947.2019.2(70).169235","url":null,"abstract":"Using the methods of physicochemical analysis (XRD, petrography, SEM, X–ray microprobe analysis) phase equilibria were firstly investigated in the ternary system La 2 O 3 –Y 2 O 3 –Yb 2 O 3 at 1100 °C. The specimens were prepared in step 1-5 mol % from nitrate solutions with their subsequent evaporation and decomposition at 800 °C for 2 h. Powders were pressed at 10 MPa into pellets of 5 mm in diameter and 4 mm in height. To study phase relationships in the ternary system La2О3 – Y2O3 – Yb2О3 thermal treatment of as-prepared samples was carried at 1100 °С. X-ray diffraction analysis of the samples was performed by a powder method at room temperature (CuKa radiation). The scanning speed of 0.05-0.1 ° 2q/min was employed in the 15° to 90 ° 2q range. The effective precision of the measurements was ± 0.0002 nm. Lattice parameters were refined by least squares fitting using the LATTIC program. The crystal-optic characteristics of the obtained phases were determined under polarized microscopes “МІН-8” and Leica. The refraction indісes were measured in immersion liquids (solution of arsenic tribromide in methylene iodide or alloys of sulfur with selenium) with accuracy ± 0.02. The solid solutions based on various polymorphous forms of constituent phases and ordered phase with a structure of the perovskite-type of LaYO3 (LaYbO3) were revealed in the system. The boundaries of mutual solubility and concentration dependences the lattice parameters for all phases have been determined. The isothermal sections of the phase diagrams for the La 2 O 3 –Y 2 O 3 –Yb 2 O 3 systems at 1100°C are characterized by the presence of one three-phase (B +C + R), four single-phase (A- La 2 O 3 , B- La 2 O 3 , R, C- Y 2 O 3 (Yb 2 O 3 )) and two-phase (A + B, B+ R, C + R, B + C) regions. The solid solutions are formed by the mechanism of the isovalent substitution. The stability of ordered phases and solid solutions are determined by the dimensional factor : in the LaYO 3 , the large size ions replace La 3+ ions, the smaller ions of the cerium series substitute both Y 3+ and La 3+ , where as all the mentioned rare earth ions may be replaced by Y 3+ ions. An ordered R-phase in the ternary system exists in the wider range of concentrations than in the binary system.","PeriodicalId":19451,"journal":{"name":"Odesa National University Herald. Chemistry","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89243277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}