North American journal of medicine & science最新文献_第10页

Immunodeficiency, Gastrointestinal Candidiasis, Wheat and Dairy Sensitivity, Abnormal Urine Arabinose, and Autism: A Case Study 免疫缺陷，胃肠道念珠菌病，小麦和乳制品敏感性，异常尿阿拉伯糖和自闭症:一个案例研究

North American journal of medicine & science Pub Date : 2010-01-31 DOI: 10.7156/V3I1P001

W. Shaw, J. Baptist, D. Geenens

{"title":"Immunodeficiency, Gastrointestinal Candidiasis, Wheat and Dairy Sensitivity, Abnormal Urine Arabinose, and Autism: A Case Study","authors":"W. Shaw, J. Baptist, D. Geenens","doi":"10.7156/V3I1P001","DOIUrl":"https://doi.org/10.7156/V3I1P001","url":null,"abstract":"A child with autism was found to have complete IgA deficiency (serum IgA <6 mg/dL; normal 33-235 mg/dL), Candidiasis of the gastrointestinal tract based on evaluation of stool testing and elevated urine arabinose, and elevated serum antibodies to wheat and dairy products. The pretreatment urinary arabinose concentration (341 mmol/mol creatinine in this child was nearly six times the mean value (60.4 mmol/mol creatinine, n=20) of normal children and over ten times the median value (31.0 mmol/mol creatinine) of normal controls. After antifungal therapy for four months, the urine was retested. At that time the urine arabinose was measured at 51 mmol/mol creatinine, a value only 15% of the baseline sample. Restriction of wheat and dairy products from the diet and antifungal therapy led to a significant decrease in autistic behaviors and increased rate of learning. The Childhood Autism Rating Scale (CARS), an observational measure of various aspects of autism, for the child has decreased from a rating of 43 (severely autistic) prior to introduction of these therapies to a value of 29 (nonautistic) after therapy.","PeriodicalId":19338,"journal":{"name":"North American journal of medicine & science","volume":"27 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2010-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83224522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

WRN protein and Werner syndrome. WRN蛋白与Werner综合征。

North American journal of medicine & science Pub Date : 2010-01-01 DOI: 10.7156/v3i4p205

Jianyuan Luo

引用次数: 7

Helping Mother Die 帮助母亲死去

North American journal of medicine & science Pub Date : 2010-01-01 DOI: 10.7156/v3i1p039

P. Triffletti

引用次数: 0

Fasting Triglyceride Concentrations are Associated with Early Mortality Following Antiretroviral Therapy in Zambia. 在赞比亚，空腹甘油三酯浓度与抗逆转录病毒疗法后的早期死亡率有关。

North American journal of medicine & science Pub Date : 2010-01-01 DOI: 10.7156/v3i2p079

Julius N Ngu, Douglas C Heimburger, Donna K Arnett, Christopher K Nyirenda, Dara Potter, Isaac Zulu, Claire N Bosire, Shashwatee Bagchi, Jiatao Ye, Benjamin H Chi, Edmond K Kabagambe

{"title":"Fasting Triglyceride Concentrations are Associated with Early Mortality Following Antiretroviral Therapy in Zambia.","authors":"Julius N Ngu, Douglas C Heimburger, Donna K Arnett, Christopher K Nyirenda, Dara Potter, Isaac Zulu, Claire N Bosire, Shashwatee Bagchi, Jiatao Ye, Benjamin H Chi, Edmond K Kabagambe","doi":"10.7156/v3i2p079","DOIUrl":"10.7156/v3i2p079","url":null,"abstract":"<p><p>BACKGROUND: In developing countries, 8 to 71% of patients initiating highly active antiretroviral therapy (HAART) die within the first year of treatment. Apart from baseline CD4 count, viral load, hemoglobin, BMI and stage of the disease, there may be other variables that contribute to AIDS-related mortality. We investigated the potential role of nutrition, lipids and insulin resistance-related phenotypes in predicting early mortality. METHODS: We recruited 210 HAART-naïve HIV/AIDS patients in Lusaka, Zambia. Dietary intake, anthropometric measurements, fasting serum insulin, glucose, and lipid profiles were assessed at baseline. Mortality was assessed after 90 days of follow-up. We used logistic regression models to identify variables associated with mortality. RESULTS: The mean±SD for age, BMI and CD4 count at baseline were 34±7.4 y, 20±3 kg/m(2) and 138±52 cells/μL, respectively. Sixteen patients (7.6%) died during follow-up. Triglyceride concentrations were associated with increased mortality [odds ratio (OR) for 1 mmol/L increase in triglyceride concentration=2.51; 95% CI: 1.34-4.71]. This association remained significant (OR=3.24; 95% CI: 1.51-6.95) after adjusting for age, gender, smoking, alcohol use, total cholesterol, BMI, CD4 count and n3 fatty acid intake. Apart from higher n3 fat intake which was inversely associated with mortality (survivors: 1.81±0.99% total energy/day vs. non-survivors 1.28±0.66% energy/day, P=0.04), there were no other macronutrients associated with mortality. CONCLUSION: Triglyceride concentrations at the time of initiating HAART are independently associated with increased risk for early mortality. If this association is confirmed in larger studies, assessment of triglycerides could become part of routine care of HIV patients initiating HAART in developing countries.</p>","PeriodicalId":19338,"journal":{"name":"North American journal of medicine & science","volume":" ","pages":"79-88"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207243/pdf/nihms-328949.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40133334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Giant Atypical Neurofibroma in the Right Thoracic Cavity of a 57-Year-Old Man: A Case Report with Review of the Literature 57岁男性右胸腔巨大非典型神经纤维瘤1例并文献复习

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P135

Rongjun Guo, Frank Chen, R. Heffner

{"title":"A Giant Atypical Neurofibroma in the Right Thoracic Cavity of a 57-Year-Old Man: A Case Report with Review of the Literature","authors":"Rongjun Guo, Frank Chen, R. Heffner","doi":"10.7156/V2I4P135","DOIUrl":"https://doi.org/10.7156/V2I4P135","url":null,"abstract":"Intrathoracic neurogenic tumors are not uncommon, but presentation as a giant mass in the thoracic cavity is rare. Although several cases of intrathoracic giant malignant peripheral nerve sheath tumor have been reported, only one case of intrathoracic giant benign neurofibroma appears in the literature. In this report, we describe a very rare case of atypical giant neurofibroma in the right thoracic cavity. The patient was a 57 year old African American man, who developed sudden cardiac arrest and passed away in the emergency room. At autopsy, a huge encapsulated firm tumor was found in the right thoracic cavity, attached to the vertebral bodies and superficially adherent to the upper and middle lobes of the right lung. This giant mass weighed 2140 grams and measured 31 x 30 x 5.5 cm. Microscopically, the tumor consisted of interweaving fascicles of spindle cells with scattered atypical nuclei. Immunohistochemical studies showed that tumor cells were focally positive for S100, and negative for SMA, desmin, calretinin, Pan CK, CK5/6, EMA, CD99, CD34 and p53. The overall morphological and immunohistochemical features were diagnostic of an atypical neurofibroma. [N A J Med Sci. 2009;2(4):135-138.]","PeriodicalId":19338,"journal":{"name":"North American journal of medicine & science","volume":"33 1","pages":"135"},"PeriodicalIF":0.0,"publicationDate":"2009-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74497191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Amplification of Complete HIV-1 Envelope Genes from Purified CD4+ T Cell Populations 纯化CD4+ T细胞群中HIV-1包膜基因的扩增

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P123

Y. Jiao, Juan Li, Wei Hua, Yanqing Gao, Tong Zhang, Hao Wu

引用次数: 0

Brief Communication: Erythema Migrans in Lyme Disease 简要交流:莱姆病的移行性红斑

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P130

Grace Perez-Lirio

引用次数: 0

Quality Control of Chinese Medicine Based on Technology Innovation 基于技术创新的中药质量控制

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P152

J. Wan, S. Li, Yi-Tao Wang, Jing Liu, J. Kang

引用次数: 0

Brief Communication: Perinatal Transmission of Hepatitis B and Prevention Strategy 简讯:乙型肝炎围产期传播及预防策略

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P127

Mph Daryl T.-Y. Lau, S. Holder

引用次数: 0

Leading Causes of Death for Older Asian Americans 老年亚裔美国人的主要死亡原因

North American journal of medicine & science Pub Date : 2009-10-31 DOI: 10.7156/V2I4P156

D. Huo, D. Lauderdale

{"title":"Leading Causes of Death for Older Asian Americans","authors":"D. Huo, D. Lauderdale","doi":"10.7156/V2I4P156","DOIUrl":"https://doi.org/10.7156/V2I4P156","url":null,"abstract":"Asian Americans are the fastest growing population in US, but data describing their disease burden are limited. For most US health statistics, Asian Americans are grouped into a single race category. We use a unique data file to identify causes of death for persons aged 65 or older in six Asian American ethnic subgroups (Chinese, Indians, Japanese, Koreans, Filipinos, and Vietnamese). Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD–10) are ranked according to the number of deaths assigned to each cause. There are a total of 76,866 death records included in this study. The 10 leading causes of death account for 85% of all deaths for Asian Americans and the top 3 causes (heart disease, cancer, and stroke) account for 68%. The rankings and relative cause-specific mortalities varied significantly across the six Asian ethnic groups. Indians had the highest relative burden of heart disease (41.6% of all deaths), followed by Filipinos (35.6%), then the other four Asian ethnic groups (~30%). Cancer, the second leading cause of death, accounted for about 26% of all deaths for Chinese, Japanese, Koreans and Vietnamese, 21% for Filipinos and 18% for Indians. Influenza and pneumonia, chronic lower respiratory disease, diabetes, accidents (unintentional injuries), and kidney disease also ranked among the top 10 causes, but the specific ranks vary across ethnic populations. Differences in the ranking are also evident by age and sex. Because of significant heterogeneity among Asian American ethnic groups, it is more informative to calculate ethnicity-specific rankings of causes of death.","PeriodicalId":19338,"journal":{"name":"North American journal of medicine & science","volume":"11 1","pages":"156"},"PeriodicalIF":0.0,"publicationDate":"2009-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78497619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2