D. Bellows, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber
{"title":"Neuro-Ophthalmic Literature Review","authors":"D. Bellows, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber","doi":"10.1080/01658107.2019.1698254","DOIUrl":"https://doi.org/10.1080/01658107.2019.1698254","url":null,"abstract":"Neuro-Ophthalmic Literature Review David Bellows, John Chen, Hui-Chen Cheng, Peter MacIntosh, Jenny Nij Bijvank, Michael Vaphiades, and Konrad Weber 10-year follow-up demonstrates the safety and efficacy of fractionated conformal radiotherapy in the treatment of optic nerve sheath meningioma Pandit R, Paris L, Rudich DS, Lesser R, Kuppersmith M, Miller N. Long-term efficacy of fractionated conformal radiotherapy for the management of primary optic nerve sheath meningioma. Br J Ophthalmol. 2019;103:1436–1440. The purpose of this retrospective study was to determine the efficacy and safety of fractionated conformal radiotherapy (FCRT) in the treatment of optic nerve sheath meningioma. The authors identified 16 patients who had more than 10 years of follow-up (mean 14.6 years) after FCRT. These patients were treated with a mean cumulative dose of 50.0 Gy over a mean of 26.9 sessions. As of the last follow-up visit, 31% of patients had an improvement in vision (two or more lines), 56% had no change in vision, and 13% (two patients) had worsened vision. Of the two patients with worsened vision, one was attributed to radiation retinopathy with macular oedema and the second to a progressive optic neuropathy. The cause of the optic neuropathy was not determined. Quantitative visual fields were available in 63% of patients. Their analysis revealed no significant change in a mean deviation between the pre-FCRT and post-FCRT studies. The authors also report “borderline” improvement in pain, proptosis or diplopia, and no improvement or worsening of colour perception. Three patients (19%) developed late toxicity including one patient who lost visual acuity from radiation retinopathy. Although as many as 30% of patients with untreated optic nerve sheath meningioma will show stable tumour size and vision, we know that the majority will progress. In this retrospective study the authors have shown that, in most patients, visual function and symptoms will stabilize or even improve following FCRT. The authors propose that this should be the first-line treatment for patients with optic nerve sheath meningioma in spite of the inevitable risks including dry eye, radiation retinopathy and radiation optic neuropathy.","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"82 1","pages":"63 - 68"},"PeriodicalIF":0.8,"publicationDate":"2019-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76118960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"List of Reviewers for Volume 43","authors":"","doi":"10.1080/01658107.2019.1704551","DOIUrl":"https://doi.org/10.1080/01658107.2019.1704551","url":null,"abstract":"","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"472 1","pages":"i - ii"},"PeriodicalIF":0.8,"publicationDate":"2019-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86732401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber, S. Wong
{"title":"Neuro-Ophthalmic Literature Review","authors":"D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber, S. Wong","doi":"10.1080/01658107.2019.1680181","DOIUrl":"https://doi.org/10.1080/01658107.2019.1680181","url":null,"abstract":"Neuro-Ophthalmic Literature Review David Bellows, Noel Chan, John Chen, Hui-Chen Cheng, Peter MacIntosh, Jenny Nij Bijvank, Michael Vaphiades, Konrad Weber, and Sui Wong “It don’t matter if you’re Black or White” Gruener AM, Poostchi A, Carey AR, Eberhart CG, Henderson AD, Chang JR, McCulley TJ. Association of giant cell arteritis with race. JAMA Ophthalmol. 2019 Aug 8. Giant cell arteritis (GCA) has widely been considered a rare disorder in black patients. In this retrospective study, the authors reviewed the charts of all patients who underwent temporal artery biopsy over a 10-year period (2007 through 2017) at Johns Hopkins School of Medicine. It should be noted that the population of Baltimore is more than 60% black and the patient population at Johns Hopkins is approximately 40% black. For the purposes of this study, a patient’s race was determined by their self-identified race in the electronic medical record. Additionally, only patients over the age of 50 were included to avoid controversy surrounding the diagnosis of giant cell arteritis in younger individuals. A total of 586 patients were identified who had undergone temporal artery biopsy during the study period. Among these patients, 65.2% were white and 28.5% were black. Biopsies that demonstrated active or healed arteritis were considered positive. Using these criteria, 16.1% of the patients were considered to have biopsy-proven giant cell arteritis (BP-GCA); 14 were black (8.4% of all black patients tested) and 75 were white (19.6% of all white patients tested). This translates to a population-adjusted rate of GCA to be 3.1 in blacks and 3.6 in whites per 100,000. The mean age of patients with BP-GCA was similar between the two groups (74.1 years for whites and 75.4 years for blacks) which is consistent with previous reports. Giant cell arteritis has long been thought to have a much greater incidence in whites than in blacks. This widely held belief may cause the clinician to have a higher threshold for obtaining temporal artery biopsy in black patients. In this study, the authors have clearly contradicted that belief. They emphasise the fact that we should have a similar threshold for obtaining temporal artery biopsy regardless of the patient’s race.","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"13 1","pages":"428 - 434"},"PeriodicalIF":0.8,"publicationDate":"2019-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82409211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber
{"title":"Neuro-Ophthalmic Literature Review","authors":"D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, J. N. Nij Bijvank, M. Vaphiades, K. Weber","doi":"10.1080/01658107.2019.1653059","DOIUrl":"https://doi.org/10.1080/01658107.2019.1653059","url":null,"abstract":"Neuro-Ophthalmic Literature Review David Bellows, Noel Chan, John Chen, Hui-Chen Cheng, Peter MacIntosh, Jenny Nij Bijvank, Michael Vaphiades, and Konrad Weber A potential biomarker for NMOSD You Y, Zhu L, Zhang T, Shen T, Fontes A, Yiannikas C, Parratt J, Barton J, Schulz A, Gupta V, Barnett MH. Evidence of Müller Glial Dysfunction in Patients with Aquaporin-4 Immunoglobulin G– Positive Neuromyelitis Optica Spectrum Disorder. Ophthalmology. 2019 Jun 1;126(6):801–10. Having a biomarker to identify patients with neuromyelitis spectrum disorder (NMOSD) before the results of laboratory testing can be obtained would be of great value in choosing the best management for patients who present with optic neuritis. In this study, the authors analysed and compared a combination of full-field electroretinography (ERG), retinal tissue volume (using spectraldomain optical coherence tomography) and Western blot immunohistochemistry in four groups of patients. These consisted of patients who were seropositive for AQP4-IgG, those who were seronegative for AQP4-IgG, those with multiple sclerosis and normal subjects. Patients who were positive for MOG-IgG were included in the NMOSD seronegative group. Altogether, 44 eyes with NMOSD, 262 eyes with multiple sclerosis and 56 normals were included in the study. The authors found no difference in scotopic ERG between three of the groups; normal subjects, those with multiple sclerosis and those with seronegative NMOSD. However, a significantly reduced b-wave amplitude was observed in patients who were seropositive for AQP4. The decrease in amplitude was not associatedwith either visual acuity or a previous history of optic neuritis. The reduction in b-wave amplitude only occurred in scotopic (as opposed to photopic) ERG which is consistent with Müller cell dysfunction. Interesting observations were made regarding the OCT of the macula. The authors noted that the thicknesses of the Henle fibre outer nuclear (HFONL) and inner segment (IS) layers were thinned in seropositive NMOSD with or without a previous history of optic neuritis. However, no thinning was noted in patients with multiple sclerosis. Quite the contrary, a small degree of thickening in HFONL was observed in patients with multiple sclerosis who had a previous history of optic neuritis. Because of the small sample size, seronegative NMOSD subjects were excluded from this portion of the study. The results of the immunohistochemical arm of the study were consistent with earlier reports that have shown AQP4 to be predominantly expressed in Müller cells. The authors were able to demonstrate that AQP4 is strongly expressed in the Henle fibre layer of the retina. This study has produced convincing evidence of Müller cell dysfunction in patients with seropositive NMOSD and, importantly, raises the possibility that a combination of OCT and ERG can be used as an early biomarker in identifying patients with seropositive NMOSD. David Bellows Aetiologies of paediatric oc","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"24 1","pages":"346 - 353"},"PeriodicalIF":0.8,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77966826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conference Report: The 14th European Neuro-Ophthalmology Society (EUNOS) Meeting, Porto, Portugal, 16-19 June 2019","authors":"D. Meira","doi":"10.1080/01658107.2019.1663877","DOIUrl":"https://doi.org/10.1080/01658107.2019.1663877","url":null,"abstract":"The 14th European Neuro-ophthalmology Society (EUNOS) Meeting took place in the city of Porto, Portugal, from 16 to 19 June 2019. The meeting was held in Alfândega Congress Centre, the historic recovered custom warehouse. The building is located on the north bank of Douro river, in the historic medieval area of the city, that has been a UNESCO world heritage site since 1996. We had the largest attendance ever with 537 registrants from 43 different countries. (Figure 1) I owe much gratitude to the EUNOS board for selecting Porto as the venue, and to the local and scientific committees for giving structure to the programme. The assumption that the organising and scientific committees worked with in planning the meeting was that each of us longs to be as excellent as possible in the work we do in the field of neuroophthalmology, this means training our clinical capabilities, broadening our knowledge and sometimes challenging our assumptions. So, the programme was diverse and covered several fields of neuroophthalmology, which allowed participants an individualised and high quality update. The first day (Sunday, 16 June) was the first time that EUNOS has had a joint meeting with the European Optic Nerve Research Network (EUPON). This scientific gathering was promoted by Patrick Yu-Wai-Man (Cambridge, UK). It featured four Optic Nerve Sessions: “Acquired Optic Neuropathies”, “From Genes to Disease”, “Neuroprotection and Neurodegeneration” and “Translational Research and Network”. The day ended with the Opening Ceremony and a Welcome Reception at the Noble Hall of the Congress Centre, on the quay of the Douro River, facing the aweinspiring Douro bridges and wine cellars, while listening to some music and tasting Port wine and Portuguese cuisine. It was an excellent social event, promoting new friendships and collaborations. (Figure 2) On the following three days the scientific programme included keynote lectures, five minisymposiums, two interactive clinical cases sessions, two teaching courses and one platform session. The EUNOS meeting had three keynote lectures:","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"1 1","pages":"341 - 345"},"PeriodicalIF":0.8,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82168188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, M. Vaphiades, K. Weber
{"title":"Neuro-Ophthalmic Literature Review","authors":"D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, M. Vaphiades, K. Weber","doi":"10.1080/01658107.2019.1645496","DOIUrl":"https://doi.org/10.1080/01658107.2019.1645496","url":null,"abstract":"Neuro-Ophthalmic Literature Review David Bellows, Noel Chan, John Chen, Hui-Chen Cheng, Michael Vaphiades, and Konrad Weber Findings support the need for immediate evaluation and, if necessary, intervention in patients with central retinal artery occlusion Mir TA, Arham AZ, Fang W, Alqahtani F, Alkhouli M, Gallo J, Hinkle DM. Acute vascular ischemic events in patients with central retinal artery occlusion in the United States: a Nationwide Study 2003–2014.Am JOphthalmol. 2019Apr 1;200:179–86. Central retinal artery occlusion (CRAO) confers a high risk of other ischaemic events. The purpose of this study was to determine the incidence of an acute ischaemic event occurring immediately following CRAO and to identify the risk factors associated with these events. Using the database from the Nationwide Inpatient Sample, the authors reviewed the records of 17,117 patients whowere admitted to a hospital in theUnited States with a diagnosis of CRAO. The primary outcome measure was the incidence of an in-hospital acute ischaemic event. The mean age of patients with CRAO was 68.4 years and 53% of the patients were female. The authors found that the most common risk factors associated with CRAO included hypertension, carotid artery stenosis, atrial fibrillation, and left-sided cardiac valve disease (most commonly aortic stenosis). The incidence of a stroke occurring during hospitalization measured 12.9% and the incidence of myocardial infarction measured 3.7%. The combined risk of stroke, transient ischaemic attack, myocardial infarction or mortality measured 19%. Not surprisingly they found that the risk of stroke was greatest in those patients with co-morbidities including hypertension, carotid artery stenosis, aortic valve disease, smoking, and alcohol abuse. The authors make a convincing argument that high-risk CRAO patients undergo immediate evaluation (with 24 h) and appropriate intervention if risk factors for other acute ischaemic events are identified. David Bellows Likelihood and timing of recurrence after first episode of optic neuritis in Asia Park K-A, Oh SY, Min J-H, Kim BJ. Incidence and timing of recurrence of optic neuritis. Graefe’s Arch Clin Exp Ophthalmol. 2019;257:651–655 This is a retrospective review evaluating the incidence and timing of recurrence after the first episode of optic neuritis in an Asian population. Patients with prior history of multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), systemic vasculitis or other forms of optic neuropathies were excluded while recurrence was defined as new attack occurring after an interval of 30 days. A total of 111 patients were included in the study and all except 2 received intravenousmethylprednisolone for 3–5 days followed by oral prednisolone 1mg/kg daily for 11 days. Two patients did not receive any treatment due to mild disease and one of them was pregnant. Eighteen (16%) patients had positive results forNMOIgG and were started on long-term immunosuppressant af","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"18 1","pages":"271 - 275"},"PeriodicalIF":0.8,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89181913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Utility of Fundus Fluorescein Angiography in Neuro-Ophthalmology","authors":"R. Littlewood, S. Mollan, I. Pepper, S. Hickman","doi":"10.1080/01658107.2019.1604764","DOIUrl":"https://doi.org/10.1080/01658107.2019.1604764","url":null,"abstract":"ABSTRACT While its use is still widespread within the medical retina field, fundus fluorescein angiography (FFA) is increasingly falling out of favour in the investigation of neuro-ophthalmological disease, with the introduction of new technologies, particularly optical coherence tomography. FFA does, however, provide useful diagnostic and prognostic information in many neuro-ophthalmological diseases including papilloedema, pseudo-papilloedema, optic neuropathies and central retinal artery occlusion to name a few. We aim to summarise the main FFA findings in each of these conditions and highlight where FFA is of most use in providing complementary information to other modes of investigation.","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"219 1","pages":"217 - 234"},"PeriodicalIF":0.8,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79265090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cosmetic Injection Techniques: A Text and Video Guide to Neurotoxins and Fillers, Second Edition","authors":"P. Macintosh","doi":"10.1080/01658107.2019.1632352","DOIUrl":"https://doi.org/10.1080/01658107.2019.1632352","url":null,"abstract":"6. Neurotoxin Injection for Glabellar Frown Lines 7. Neurotoxin Injection for Forehead Wrinkles 8. Neurotoxin Injection for Smile Lines and Crow’s Feet 9. Neurotoxin Injection for Lateral Brow Lift 10. Neurotoxin Injection for Chemical Brow Lift 11. Neurotoxin Injection for Lower Eyelid Roll 12. Neurotoxin Injection for Bunny Lines 13. Neurotoxin Injection for Nasal Tip Lift 14. Neurotoxin Injection for Nasal Flare 15. Neurotoxin Injection for Elevating the Oral Commissures 16. Neurotoxin Injection for Lip Lift 17. Neurotoxin Injection for Smoker’s Lines 18. Neurotoxin Injection for Gummy Smile 19. Neurotoxin Injection for Dimpled Chin 20. Neurotoxin Injection for Platysmal Banding 21. Neurotoxin Injection for Necklace Lines 22. Neurotoxin Injection for the Décolleté 23. Neurotoxin Injection for Nefertiti Neck Lift 24. Neurotoxin Injection for Masseter Hypertrophy 25. Neurotoxin Injection for Parotid Gland Hypertrophy 26. Neurotoxin Injection for Submandibular Gland Hypertrophy 27. Neurotoxin Injection for Gustatory Sweating (Frey Syndrome) 28. Neurotoxin Injection for Profusely Sweating Underarms 29. Neurotoxin Injection for Profusely Sweating Scalp and Forehead 30. Neurotoxin Injection for Profusely Sweating Hands 31. Neurotoxin Injection for Profusely Sweating Feet 32. Neurotoxin Injection for Chronic Migraines 33. Management of Neurotoxin Injection Complications","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"46 1","pages":"269 - 270"},"PeriodicalIF":0.8,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90634193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, S. Wong, M. Vaphiades
{"title":"Neuro-Ophthalmic Literature Review","authors":"D. Bellows, N. Chan, John J. Chen, Hui-Chen Cheng, P. Macintosh, S. Wong, M. Vaphiades","doi":"10.1080/01658107.2019.1610313","DOIUrl":"https://doi.org/10.1080/01658107.2019.1610313","url":null,"abstract":"Neuro-Ophthalmic Literature Review David Bellows, Noel Chan, John Chen, Hui-Chen Cheng, Peter MacIntosh, Sui Wong, and Michael Vaphiades Asian or Caucasian? In Optic Neuritis it Makes a Difference KimH, Park KA,Oh SY,Min JH, KimBJ. Association of optic neuritis with neuromyelitis optica spectrum disorder and multiple sclerosis in Korea. Korean J Ophthalmol. 2019 Feb 1;33(1):82–90. There are significant differences in the expression of optic neuritis between different ethnic groups. In particular, neuromyelitis optica has been shown to be more prevalent in Asians, Indians and Blacks. It is important to recognise this distinction because early identification and intervention can improve outcomes. This retrospective study was performed on 125 eyes of 91 Korean patients presenting to the Neuroophthalmology Department at Samsung Medical Center with acute optic neuritis. These patients were eventually diagnosed with idiopathic optic neuritis, neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis. The diagnoses of NMOSD and multiple sclerosis were based upon the Wingerchuk or McDonald criteria, respectively. These patients were followed for six months to 16 years (mean 3.7 years) and all but seven of the patients were tested for NMO-IgG. There are several interesting findings that distinguish optic neuritis in Asians from the same entity in Caucasians. These include the fact that only 63%of the patients were female, only 56% of eyes had pain and disk swelling was noted in 53% of eyes. During the follow-up period, 80%of patientswere diagnosedwith idiopathic optic neuritis, 15% were diagnosed with NMOSD and 4% were diagnosed with definite multiple sclerosis. Unlike patients in the Optic Neuritis Treatment Trial (ONTT), where 95% achieved a visual acuity of 20/40 or better, only 73% of eyes in this study achieved a similar outcome. This paper emphasises the importance of testing for NMO-IgG antibodies in all patients with acute optic neuritis, particularly in those of Asian ethnicity. Early diagnoses and intervention in these patients can significantly improve outcomes. David Bellows Endoscopic Orbital Decompression in Acute Optic Neuritis with Sinusitis? Neo, WL, Chin, DCW, Huang, XY. Rhinogenous optic neuritis with full recovery of vision – The role of endoscopic optic nerve decompression and a review of literature. Am J Otolaryngol. 2018 Nov;39(6):791–795. Paranasal sinusitis may result in different orbital complications and infrequently optic neuritis. Traditionally, themainstay of treatment is intravenous antibiotics with or without steroids. The authors present a case of acute painless optic neuritis with disc swelling in a patient with pansinusitis and nasal polyposis. Computer tomography showed opacification adjacent to the right orbital apex while magnetic resonance imaging showed extensive inflammatory changes towards the lesser wing of the sphenoid and orbital walls. There was no mucocoele or evidence of direct compression. Nevert","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"81 1","pages":"208 - 211"},"PeriodicalIF":0.8,"publicationDate":"2019-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90626510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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