Nihon Kyobu Shikkan Gakkai zasshi最新文献_第3页

[A case of primary acute pulmonary cavitation in sarcoidosis complicated by multiple nodular lesions in the central nervous system]. [结节病并发中枢神经系统多发结节性病变原发性急性肺空化1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

T Nakayama, S Hashimito, K Arai, H Nakazawa, T Horie

{"title":"[A case of primary acute pulmonary cavitation in sarcoidosis complicated by multiple nodular lesions in the central nervous system].","authors":"T Nakayama, S Hashimito, K Arai, H Nakazawa, T Horie","doi":"","DOIUrl":"","url":null,"abstract":"A 20-year-old man visited our hospital complaining of headache and a dry cough. Chest X-ray and chest CT showed bilateral hilar and mediastinal lymphadenopathy, multiple cavitations with thin, smooth walls, and diffuse granular shadows. A transbronchial biopsy specimen revealed sarcoid granuloma. Primary acute pulmonary cavitation of sarcoidosis was diagnosed, since there was no evidence of infection, emphysematous change, fibrotic or cystic bronchiectatic change on chest X-ray. EEG, contrast enhancement of brain CT scans and MRI were performed because the patient complained of headache. EEG showed a high voltage paroxysmal slow wave and giant build-up, whereas brain CT showed no abnormalities. T1-weighted MRI with gadolinium enhancement showed multiple high intensity nodules in the convexity, brain stem, and spinal cord. Corticosteroid therapy (60 mg/day) was started. After 1 week of treatment, the headache ceased. After 2 weeks of treatment, both the cavities in the lung field's and the nodules in the central nervous system disappeared. Therefore, the dose of corticosteroids was gradually reduced to a maintenance dose of 5 mg/day, and no relapse was noted. We report a very rare case of primary acute pulmonary cavitation in sarcoidosis complicated by multiple nodular lesions in the central nervous system.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1400-6"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20489507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)]. [膀胱内注射卡介苗致间质性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01 DOI: 10.11389/JJRS1963.35.1383

K. Naoki, K. Yamaguchi, K. Soejima, T. Aoki, T. Inoue, N. Satou, H. Shimada, K. Fukunaga, H. Kudo, M. Kanazawa

{"title":"[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)].","authors":"K. Naoki, K. Yamaguchi, K. Soejima, T. Aoki, T. Inoue, N. Satou, H. Shimada, K. Fukunaga, H. Kudo, M. Kanazawa","doi":"10.11389/JJRS1963.35.1383","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1383","url":null,"abstract":"A 61-year-old man with superficial bladder cancer, which was detected after he complained of hematuria, was treated three times with intravesical BCG administration. Since liver dysfunction was detected thereafter, he was admitted to our hospital. Three days after admission, he complained of dyspnea on exertion associated with severe hypoxemia, as well as abnormal findings on chest X-ray, i.e. extensive bilateral lung densities. We performed bronchoscopic examination and obtained bronchoalveolar lavage fluid (BALF) and lung biopsy specimens (TBLB). In the BALF, a marked increase in the total cell number, particularly lymphocytes with a high CD4/CD8 ratio was noted. TBLB specimens revealed the lesions to be numerous non-caseating granulomas. We failed to obtain definite evidence of BCG in the sputum, urine, blood, and BALF. Instead, we found that a lymphocyte stimulation test for BCG (DLST) was strongly positive. Based on these findings, severe interstitial pneumonia probably induced by hypersensitivity against BCG, was diagnosed. Anti-tuberculous agents, and steroid-pulse therapy followed by oral administration of relatively low dose of steroid ameliorated the abnormal conditions, including chest X-ray film findings and hypoxemia. The population of lymphocytes and CD4/CD8 ratio in the BALF were reduced as well. Serious interstitial pneumonia was induced by the intravesical administration of BCG, which resulted in transitional changes in the BALF cell component.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"36 1","pages":"1383-8"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86769117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)]. [膀胱内注射卡介苗致间质性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

K Naoki, K Yamaguchi, K Soejima, T Aoki, T Inoue, N Satou, H Shimada, K Fukunaga, H Kudo, M Kanazawa

{"title":"[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)].","authors":"K Naoki, K Yamaguchi, K Soejima, T Aoki, T Inoue, N Satou, H Shimada, K Fukunaga, H Kudo, M Kanazawa","doi":"","DOIUrl":"","url":null,"abstract":"A 61-year-old man with superficial bladder cancer, which was detected after he complained of hematuria, was treated three times with intravesical BCG administration. Since liver dysfunction was detected thereafter, he was admitted to our hospital. Three days after admission, he complained of dyspnea on exertion associated with severe hypoxemia, as well as abnormal findings on chest X-ray, i.e. extensive bilateral lung densities. We performed bronchoscopic examination and obtained bronchoalveolar lavage fluid (BALF) and lung biopsy specimens (TBLB). In the BALF, a marked increase in the total cell number, particularly lymphocytes with a high CD4/CD8 ratio was noted. TBLB specimens revealed the lesions to be numerous non-caseating granulomas. We failed to obtain definite evidence of BCG in the sputum, urine, blood, and BALF. Instead, we found that a lymphocyte stimulation test for BCG (DLST) was strongly positive. Based on these findings, severe interstitial pneumonia probably induced by hypersensitivity against BCG, was diagnosed. Anti-tuberculous agents, and steroid-pulse therapy followed by oral administration of relatively low dose of steroid ameliorated the abnormal conditions, including chest X-ray film findings and hypoxemia. The population of lymphocytes and CD4/CD8 ratio in the BALF were reduced as well. Serious interstitial pneumonia was induced by the intravesical administration of BCG, which resulted in transitional changes in the BALF cell component.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1383-8"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20488150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of DNA topoisomerase I inhibitor on the transduction efficiency of an deno-associated virus vector in human airway epithelial cells]. [DNA拓扑异构酶I抑制剂对人气道上皮细胞中脱氧相关病毒载体转导效率的影响]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

S Teramoto, T Matsuse, E Ohga, H Katayama, Y Fukuchi, Y Ouchi

引用次数: 0

[A resected case of intralobar pulmonary sequestration with increased serum tumor markers, CA19-9, CA125 and NCC-ST-439]. [1例切除的肺叶内肺隔离患者血清肿瘤标志物CA19-9、CA125和nc - st -439升高]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01 DOI: 10.11389/JJRS1963.35.1425

Haruhiko Nakamura, T. Katsumi, Shinichi Nagata, M. Saito, C. Konaka, H. Kato

引用次数: 10

[A case of multifocal Langerhans cell granulomatosis: a BAL follow up study]. [多灶性朗格汉斯细胞肉芽肿病1例:BAL随访研究]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

H Tomioka, R Fujiyama, H Ohnishi, T Sakurai, K Tada, H Sakamoto, H Iwasaki, K Imanaka, K Hashimoto

引用次数: 0

[A resected case of intralobar pulmonary sequestration with increased serum tumor markers, CA19-9, CA125 and NCC-ST-439]. [1例切除的肺叶内肺隔离患者血清肿瘤标志物CA19-9、CA125和nc - st -439升高]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

H Nakamura, T Katsumi, S Nagata, M Saito, C Konaka, H Kato

引用次数: 0

[A case of expanding pulmonary aspergilloma]. [扩张性肺曲菌瘤1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

Y Nakagawa, K Shimazu, M Ebihara, K Aman

引用次数: 0

[Extracorporeal membrane oxygenation for acute respiratory failure induced by Legionella pneumoniae. (Case report)]. 体外膜氧合治疗肺炎军团菌急性呼吸衰竭。(病例报告)]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

H Nakajima, T Kutsuwada, T Ohdaira, A Saito, K Satoh, K Igarashi, E Suzuki, M Arakawa

引用次数: 0

[Sero-negative tsutsugamushi disease (scrub typhus) diagnosed by polymerase chain reaction]. 聚合酶链反应诊断血清阴性恙虫病(恙虫病)。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

M Sugita, M Shigeta, Y Miyake, T Sakamoto, S Aoki, R Matsuoka, T Nagayama, S Aoki, R Matsuoka

{"title":"[Sero-negative tsutsugamushi disease (scrub typhus) diagnosed by polymerase chain reaction].","authors":"M Sugita, M Shigeta, Y Miyake, T Sakamoto, S Aoki, R Matsuoka, T Nagayama, S Aoki, R Matsuoka","doi":"","DOIUrl":"","url":null,"abstract":"We report a case of sero-negative tsutsugamushi disease diagnosed by polymerase chain reaction (PCR). A 54-year-old man who worked in Nagano prefecture presented with flu-like symptoms that did not respond to cephalosporin therapy. On admission to another hospital, chest roentgenography revealed abnormal shadows; liver dysfunction was also present. Despite therapy, the patient's condition gradually worsened and he was transferred to our intensive care unit. Erythema on all extremities and scabs on the right medial femoral region and the dorsum of the left foot suggested a diagnosis of tsutsugamushi disease. We administered minocycline and gave percutaneous cardiopulmonary support for adult respiratory distress syndrome. Despite all efforts, the patient died. Although serologic tests were not positive, Karp strains of R. tsutsugamuschi were identified on PCR amplification. Autopsy revealed evidence of acute hemorrhagic pancreatitis, which has not been reported previously in tsutsugamushi disease. We conclude that PCR techniques may be useful in confirming a diagnosis of early tsutsugamushi disease.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1368-71"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20488147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0