Nihon Kyobu Shikkan Gakkai zasshi最新文献_第3页

[Estimation of respiratory muscle endurance using an inspiratory threshold loading device in patients with chronic pulmonary emphysema and in elderly subjects]. [使用吸气阈值负荷装置估计慢性肺气肿患者和老年人的呼吸肌耐力]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

M Abe, Y Hosokawa, T Horie

{"title":"[Estimation of respiratory muscle endurance using an inspiratory threshold loading device in patients with chronic pulmonary emphysema and in elderly subjects].","authors":"M Abe, Y Hosokawa, T Horie","doi":"","DOIUrl":"","url":null,"abstract":"We studied respiratory muscle endurance with an inspiratory threshold loading (ITL) device using Martyn's method (2-min incremental loading test) in 9 patients with chronic pulmonary emphysema (CPE patients) and in 9 elderly subjects with no lung disease (NE subjects), and their endurance was compared with that of 9 normal young subjects (NY subjects). In 11 cases (8 CPE patients and 3 NE subjects) a treadmill exercise test was performed and cardiopulmonary parameters obtained from the ITL and treadmill tests were compared. The maximum weight tolerated for 2 minutes (Wmax) and the mean peak inspiratory mouth pressure/maximum inspiratory mouth pressure ratio at the maximum load (Ppk/MIP at Max Load) were used as indices of respiratory muscle endurance. CPE patients had significantly decreased Wmax compared with those of NE and NY subjects. Wmax in all cases positively correlated with Ppk/MIP at Max Load, and endurance time of both the ITL and treadmill tests. During both tests, SaO2 significantly decreased, and heart rate and mean blood pressure significantly increased. There was less change in SaO2 and heart rate during the ITL test than during the treadmill test, and neither arrhythmias nor ST changes on ECG were observed during the ITL test. These results indicate that the ITL test can be easily and safely employed in CPE patients and elderly subjects to estimate respiratory muscle endurance.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1338-46"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20488275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)]. [膀胱内注射卡介苗致间质性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01 DOI: 10.11389/JJRS1963.35.1383

K. Naoki, K. Yamaguchi, K. Soejima, T. Aoki, T. Inoue, N. Satou, H. Shimada, K. Fukunaga, H. Kudo, M. Kanazawa

{"title":"[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)].","authors":"K. Naoki, K. Yamaguchi, K. Soejima, T. Aoki, T. Inoue, N. Satou, H. Shimada, K. Fukunaga, H. Kudo, M. Kanazawa","doi":"10.11389/JJRS1963.35.1383","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1383","url":null,"abstract":"A 61-year-old man with superficial bladder cancer, which was detected after he complained of hematuria, was treated three times with intravesical BCG administration. Since liver dysfunction was detected thereafter, he was admitted to our hospital. Three days after admission, he complained of dyspnea on exertion associated with severe hypoxemia, as well as abnormal findings on chest X-ray, i.e. extensive bilateral lung densities. We performed bronchoscopic examination and obtained bronchoalveolar lavage fluid (BALF) and lung biopsy specimens (TBLB). In the BALF, a marked increase in the total cell number, particularly lymphocytes with a high CD4/CD8 ratio was noted. TBLB specimens revealed the lesions to be numerous non-caseating granulomas. We failed to obtain definite evidence of BCG in the sputum, urine, blood, and BALF. Instead, we found that a lymphocyte stimulation test for BCG (DLST) was strongly positive. Based on these findings, severe interstitial pneumonia probably induced by hypersensitivity against BCG, was diagnosed. Anti-tuberculous agents, and steroid-pulse therapy followed by oral administration of relatively low dose of steroid ameliorated the abnormal conditions, including chest X-ray film findings and hypoxemia. The population of lymphocytes and CD4/CD8 ratio in the BALF were reduced as well. Serious interstitial pneumonia was induced by the intravesical administration of BCG, which resulted in transitional changes in the BALF cell component.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"36 1","pages":"1383-8"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86769117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)]. [膀胱内注射卡介苗致间质性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

K Naoki, K Yamaguchi, K Soejima, T Aoki, T Inoue, N Satou, H Shimada, K Fukunaga, H Kudo, M Kanazawa

{"title":"[A case of interstitial pneumonia induced by intravesical administration of bacillus Calmette-Guerin (BCG)].","authors":"K Naoki, K Yamaguchi, K Soejima, T Aoki, T Inoue, N Satou, H Shimada, K Fukunaga, H Kudo, M Kanazawa","doi":"","DOIUrl":"","url":null,"abstract":"A 61-year-old man with superficial bladder cancer, which was detected after he complained of hematuria, was treated three times with intravesical BCG administration. Since liver dysfunction was detected thereafter, he was admitted to our hospital. Three days after admission, he complained of dyspnea on exertion associated with severe hypoxemia, as well as abnormal findings on chest X-ray, i.e. extensive bilateral lung densities. We performed bronchoscopic examination and obtained bronchoalveolar lavage fluid (BALF) and lung biopsy specimens (TBLB). In the BALF, a marked increase in the total cell number, particularly lymphocytes with a high CD4/CD8 ratio was noted. TBLB specimens revealed the lesions to be numerous non-caseating granulomas. We failed to obtain definite evidence of BCG in the sputum, urine, blood, and BALF. Instead, we found that a lymphocyte stimulation test for BCG (DLST) was strongly positive. Based on these findings, severe interstitial pneumonia probably induced by hypersensitivity against BCG, was diagnosed. Anti-tuberculous agents, and steroid-pulse therapy followed by oral administration of relatively low dose of steroid ameliorated the abnormal conditions, including chest X-ray film findings and hypoxemia. The population of lymphocytes and CD4/CD8 ratio in the BALF were reduced as well. Serious interstitial pneumonia was induced by the intravesical administration of BCG, which resulted in transitional changes in the BALF cell component.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1383-8"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20488150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of DNA topoisomerase I inhibitor on the transduction efficiency of an deno-associated virus vector in human airway epithelial cells]. [DNA拓扑异构酶I抑制剂对人气道上皮细胞中脱氧相关病毒载体转导效率的影响]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

S Teramoto, T Matsuse, E Ohga, H Katayama, Y Fukuchi, Y Ouchi

引用次数: 0

[A resected case of intralobar pulmonary sequestration with increased serum tumor markers, CA19-9, CA125 and NCC-ST-439]. [1例切除的肺叶内肺隔离患者血清肿瘤标志物CA19-9、CA125和nc - st -439升高]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01 DOI: 10.11389/JJRS1963.35.1425

Haruhiko Nakamura, T. Katsumi, Shinichi Nagata, M. Saito, C. Konaka, H. Kato

引用次数: 10

[A case of multifocal Langerhans cell granulomatosis: a BAL follow up study]. [多灶性朗格汉斯细胞肉芽肿病1例:BAL随访研究]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

H Tomioka, R Fujiyama, H Ohnishi, T Sakurai, K Tada, H Sakamoto, H Iwasaki, K Imanaka, K Hashimoto