Nihon Kyobu Shikkan Gakkai zasshi最新文献_第2页

[Effect of dopamine receptor on hypoxic ventilatory response]. 多巴胺受体对低氧通气反应的影响。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1318

S. Osanai, Y. Akiba, H. Matsumoto, H. Nakano, K. Kikuchi

{"title":"[Effect of dopamine receptor on hypoxic ventilatory response].","authors":"S. Osanai, Y. Akiba, H. Matsumoto, H. Nakano, K. Kikuchi","doi":"10.11389/JJRS1963.35.1318","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1318","url":null,"abstract":"We studied the effect of intravenous administration of a dopamine (DA) agonist and antagonist on the hypoxic response of phrenic nerve activity in anesthetized, vagotomized and mechanically ventilated rabbits. The experiments were performed in both intact and carotid sinus denervated animals. In the intact animals, hypoxic challenge (FIO2 = 0.10) increased the amplitude of integrated phrenic nerve activity (iPNA) without any alteration in respiratory frequency. In the carotid sinus denervated animals, the hypoxia progressively depressed iPNA. Neither the DA antagonist, haloperidol (0.5mg/kg i.v.), nor the DA agonist, apomorphine (0.3mg/kg, i.v.) changed the iPNA during normoxia in either the intact or denervated group. Administration of haloperidol enhanced iPNA response to hypoxia in the intact group. Apomorphine decreased the hypoxic response to iPNA. Although apomorphine did not change the control hypoxic response to iPNA in the denervated group, haloperidol augmented hypoxic respiratory depression in the carotid sinus denervated group. Therefore, we concluded that the effect of DA on peripheral chemoreceptors inhibits the hypoxic ventilatory response, but stimulates the hypoxic ventilatory response in the central nervous system.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"44 1","pages":"1318-23"},"PeriodicalIF":0.0,"publicationDate":"1997-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77567029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

[A case of non-specific interstitial pneumonia associated with psoriasis vulgaris and polymyalgia rheumatica]. 【非特异性间质性肺炎合并寻常型银屑病和风湿性多肌痛1例】。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1395

K. Kawakami, J. Kadota, K. Abe, K. Iida, M. Kaseda, S. Kawamoto, T. Fujii, T. Matsuo, S. Kohno

引用次数: 6

[Clinical investigation of three cases of pulmonary eosinophilic granuloma]. 【肺嗜酸性肉芽肿3例临床分析】。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1407

W. Matsuyama, A. Mizoguchi, F. Iwami, Y. Hirotsu, M. Kawabata, M. Osame

{"title":"[Clinical investigation of three cases of pulmonary eosinophilic granuloma].","authors":"W. Matsuyama, A. Mizoguchi, F. Iwami, Y. Hirotsu, M. Kawabata, M. Osame","doi":"10.11389/JJRS1963.35.1407","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1407","url":null,"abstract":"Patient 1: An 18-year-old woman was admitted to our hospital with pneumothorax. She had no history of smoking. Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. She recovered without therapy 3 months later and a chest CT taken at that time was normal. She began smoking, 3 years later, and bore two children. She is without recurrence after 8 years. Patient 2: A 23-year-old man was admitted to our hospital with pneumothorax. He had a smoking history (index = 180). Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. He stopped smoking and recovered without therapy one month later, and subsequently, his CT findings returned to normal. Two years later, he began smoking again, but has no relapse. Patient 3: A 21-year-old man was admitted to our hospital with pneumothorax. He had no history of smoking. A chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. Diabetes insipidus was subsequently noted. Dyspnea persisted, and he recovered 4 months later after steroid treatment. He was without relapse 2 years later but the multiple cysts remained. We report three cases of pulmonary eosinophilic granuloma, and discuss their pertinent clinical features.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"5 1","pages":"1407-12"},"PeriodicalIF":0.0,"publicationDate":"1997-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88438486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Clinico-pathological analysis of interstitial pneumonia associated with collagen vascular disease in patients with lung cancer]. 肺癌患者间质性肺炎合并胶原血管病变的临床病理分析

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1324

S. Ohno, K. Oshikawa, S. Kitamura, K. Saitoh

{"title":"[Clinico-pathological analysis of interstitial pneumonia associated with collagen vascular disease in patients with lung cancer].","authors":"S. Ohno, K. Oshikawa, S. Kitamura, K. Saitoh","doi":"10.11389/JJRS1963.35.1324","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1324","url":null,"abstract":"We investigated interstitial pneumonia associated with collagen vascular disease (IP-CVD) in association with lung cancer. Seventy-three cases of IP-CVD were included in this study. Nine (12%) of the 73 cases were associated with lung cancer, one of which had double lung cancers. The histological types of the cancers were adenocarcinoma (5 cases), epidermoid carcinoma (2 cases), small cell carcinoma, large cell carcinoma and large cell neuroendocrine carcinoma (one case each). The lesions were located in the central or peripheral lung in 3 and 7 of the ten cancers, respectively. Of the seven cases diagnosed as having IP-CVD followed by lung cancer, five had stage I disease, and one each of the remaining two cases was in stage IIIA and stage IV. Six of the seven peripheral cancer lesions which were resected or autopsied could be analyzed with regard to the topographical relationship between the primary site and fibrotic lesions. Only three cancers were encased by or in close proximity to, honeycomb lung, although most of the lung cancers arose in relation to fibrotic lesions. Moreover, the acute exacerbation of IP-CVD after operation or chemotherapy without thoracic irradiation should be monitored carefully.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"33 1","pages":"1324-9"},"PeriodicalIF":0.0,"publicationDate":"1997-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91066487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

[A case of acute eosinophilic pneumonia due to Sho-saiko-to]. [shoo -saiko-to致急性嗜酸性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1372

Y. Kobashi, M. Nakajima, Y. Niki, T. Matsushima

引用次数: 8

[A case of Goodpasture's syndrome with myeloperoxidase specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) during chronic interstitial pneumonia]. 慢性间质性肺炎伴髓过氧化物酶特异性抗中性粒细胞胞浆自身抗体(MPO-ANCA)的Goodpasture综合征1例。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-25 DOI: 10.11389/JJRS1963.35.1356

A. Inoue, N. Ino-oka, K. Konishi, Y. Shindoh, T. Suzuki, Y. Ono

{"title":"[A case of Goodpasture's syndrome with myeloperoxidase specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) during chronic interstitial pneumonia].","authors":"A. Inoue, N. Ino-oka, K. Konishi, Y. Shindoh, T. Suzuki, Y. Ono","doi":"10.11389/JJRS1963.35.1356","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1356","url":null,"abstract":"A 55-year-old man was admitted to our hospital with of hemoptysis, progression of anemia and renal failure in February, 1996. Idiopathic interstitial pneumonia had been diagnosed and he had been followed at a regional hospital since 1988. On the third day after admission, he suffered from sudden and massive hemoptysis. Goodpasture's syndrome was diagnosed because anti-GBM antibody was detected in serum. A high titer of MPO-ANCA was also recognized simultaneously. Steroid pulse therapy, immunosuppressive therapy, and plasmapheresis were begun, but he died on the 28th hospital day because of severe hypoxemia and multi-organ failure. Histological examination after autopsy revealed crescentic glomerulonephritis with linear deposition of IgG in the glomerular capillary wall, and interstitial pneumonia accompanied by massive alveolar hemorrhage. It was suggested that in this patient, not only anti-GBM antibody but also circulating MPO-ANCA might have participated in the progression of the crescentic glomerulonephritis and alveolar hemorrhage observed in Goodpasture's syndrome.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"32 1","pages":"1356-62"},"PeriodicalIF":0.0,"publicationDate":"1997-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87972789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[Clinical investigation of three cases of pulmonary eosinophilic granuloma]. 【肺嗜酸性肉芽肿3例临床分析】。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

W Matsuyama, A Mizoguchi, F Iwami, Y Hirotsu, M Kawabata, M Osame

{"title":"[Clinical investigation of three cases of pulmonary eosinophilic granuloma].","authors":"W Matsuyama, A Mizoguchi, F Iwami, Y Hirotsu, M Kawabata, M Osame","doi":"","DOIUrl":"","url":null,"abstract":"Patient 1: An 18-year-old woman was admitted to our hospital with pneumothorax. She had no history of smoking. Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. She recovered without therapy 3 months later and a chest CT taken at that time was normal. She began smoking, 3 years later, and bore two children. She is without recurrence after 8 years. Patient 2: A 23-year-old man was admitted to our hospital with pneumothorax. He had a smoking history (index = 180). Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. He stopped smoking and recovered without therapy one month later, and subsequently, his CT findings returned to normal. Two years later, he began smoking again, but has no relapse. Patient 3: A 21-year-old man was admitted to our hospital with pneumothorax. He had no history of smoking. A chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. Diabetes insipidus was subsequently noted. Dyspnea persisted, and he recovered 4 months later after steroid treatment. He was without relapse 2 years later but the multiple cysts remained. We report three cases of pulmonary eosinophilic granuloma, and discuss their pertinent clinical features.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1407-12"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20489508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Nasopharyngeal myiasis during mechanical ventilation]. [机械通气期间鼻咽癌]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

A Yoshitomi, A Sato, T Suda, K Chida

引用次数: 0

[Extracorporeal membrane oxygenation for acute respiratory failure induced by Legionella pneumoniae. (Case report)]. 体外膜氧合治疗肺炎军团菌急性呼吸衰竭。(病例报告)]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01 DOI: 10.11389/JJRS1963.35.1363

H. Nakajima, T. Kutsuwada, T. Ohdaira, A. Saito, K. Satoh, K. Igarashi, E. Suzuki, M. Arakawa

{"title":"[Extracorporeal membrane oxygenation for acute respiratory failure induced by Legionella pneumoniae. (Case report)].","authors":"H. Nakajima, T. Kutsuwada, T. Ohdaira, A. Saito, K. Satoh, K. Igarashi, E. Suzuki, M. Arakawa","doi":"10.11389/JJRS1963.35.1363","DOIUrl":"https://doi.org/10.11389/JJRS1963.35.1363","url":null,"abstract":"We report a case of severe legionella pneumonia with acute respiratory failure, successfully managed with veno-venous extracorporeal membrane oxygenation (VV-ECMO). The patient presented with 4-day history of fever and cough. He was in critical condition, with exacerbated respiratory failure. Mechanical ventilation, volume replacement and antibiotic therapy were initiated. Despite increasing mechanical ventilatory support (FiO2 100%, TV 10 ml/kg, f 30/min, PEEP 5 cmH20), PaO2 fell below 40Torr and life sustaining measures were undertaken. VV-ECMO (flow 30 ml/kg/min) was commenced, and the patient responded well, with an elevation of PaO2. Erythromycin therapy was effective against the pneumonia. VV-ECMO was maintained for 92 hours, mechanical ventilation was successfully discontinued 11 days after and the patient was discharged 82 days after cessation of ventilator support. Serum antibody examination proved legionella infection. VV-ECMO may have a role in the management of patients with acute respiratory failure caused by bacterial pneumonia.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"67 1","pages":"1363-7"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76146747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

[Estimation of respiratory muscle endurance using an inspiratory threshold loading device in patients with chronic pulmonary emphysema and in elderly subjects]. [使用吸气阈值负荷装置估计慢性肺气肿患者和老年人的呼吸肌耐力]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01

M Abe, Y Hosokawa, T Horie

{"title":"[Estimation of respiratory muscle endurance using an inspiratory threshold loading device in patients with chronic pulmonary emphysema and in elderly subjects].","authors":"M Abe, Y Hosokawa, T Horie","doi":"","DOIUrl":"","url":null,"abstract":"We studied respiratory muscle endurance with an inspiratory threshold loading (ITL) device using Martyn's method (2-min incremental loading test) in 9 patients with chronic pulmonary emphysema (CPE patients) and in 9 elderly subjects with no lung disease (NE subjects), and their endurance was compared with that of 9 normal young subjects (NY subjects). In 11 cases (8 CPE patients and 3 NE subjects) a treadmill exercise test was performed and cardiopulmonary parameters obtained from the ITL and treadmill tests were compared. The maximum weight tolerated for 2 minutes (Wmax) and the mean peak inspiratory mouth pressure/maximum inspiratory mouth pressure ratio at the maximum load (Ppk/MIP at Max Load) were used as indices of respiratory muscle endurance. CPE patients had significantly decreased Wmax compared with those of NE and NY subjects. Wmax in all cases positively correlated with Ppk/MIP at Max Load, and endurance time of both the ITL and treadmill tests. During both tests, SaO2 significantly decreased, and heart rate and mean blood pressure significantly increased. There was less change in SaO2 and heart rate during the ITL test than during the treadmill test, and neither arrhythmias nor ST changes on ECG were observed during the ITL test. These results indicate that the ITL test can be easily and safely employed in CPE patients and elderly subjects to estimate respiratory muscle endurance.","PeriodicalId":19255,"journal":{"name":"Nihon Kyobu Shikkan Gakkai zasshi","volume":"35 12","pages":"1338-46"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20488275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0