Immuno-Oncology and Technology最新文献

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192P Analysis of tumor-associated macrophages and tumor-infiltrating lymphocytes within the tumor microenvironment of primary tumors and matched brain metastases 192P 原发性肿瘤和匹配脑转移瘤肿瘤微环境中的肿瘤相关巨噬细胞和肿瘤浸润淋巴细胞分析
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100651
M. Kleinberger, D. Cifci, C. Paiato, E. Tomasich, M. Mair, A. Steindl, Z. Carrero, L. Berchtold, J. Hainfellner, L. Müllauer, G. Heller, M. Preusser, J. Kather, A. Berghoff
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引用次数: 0
114P Real-world insights on pan-cancer immune checkpoint inhibitor treatment: Initial findings of a Belgian multicenter study 114P 关于泛癌症免疫检查点抑制剂治疗的真实世界见解:比利时多中心研究的初步发现
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100586
A.T.L. Verbiest, D. Delombaerde, M. Verhaert, L. Tack, C.L. Oeste, L. Cool, L. Croes, I. Bassez, D.F.E. Hens, C. Franssen, S. Aspeslagh, V. Geldhof, P.R. Debruyne, C. Vulsteke
{"title":"114P Real-world insights on pan-cancer immune checkpoint inhibitor treatment: Initial findings of a Belgian multicenter study","authors":"A.T.L. Verbiest, D. Delombaerde, M. Verhaert, L. Tack, C.L. Oeste, L. Cool, L. Croes, I. Bassez, D.F.E. Hens, C. Franssen, S. Aspeslagh, V. Geldhof, P.R. Debruyne, C. Vulsteke","doi":"10.1016/j.iotech.2023.100586","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100586","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"167 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138621407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
152P Discovery of best-in-class dual-acting A2AR/A2BR antagonists that are functional in high adenosine environment 152P 发现能在高腺苷环境中发挥作用的一流双效 A2AR/A2BR 拮抗剂
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100663
N. Katagihallimath, R. Nandishaiah, S. Sharma, S. Venkatesan, R. Rao, N. Bharatham, M. Gupta, D. Kundu, H. K. Kotakonda, R. R. Kalainesan, S. Reddy, B. Tewary, S. Muley, A. Gangoli, P. C. Uthappa, L. Maitreyi, B. Venkatraman, S. Datta, S. V. R. Sody, B. Majumder, S. Hameed
{"title":"152P Discovery of best-in-class dual-acting A2AR/A2BR antagonists that are functional in high adenosine environment","authors":"N. Katagihallimath, R. Nandishaiah, S. Sharma, S. Venkatesan, R. Rao, N. Bharatham, M. Gupta, D. Kundu, H. K. Kotakonda, R. R. Kalainesan, S. Reddy, B. Tewary, S. Muley, A. Gangoli, P. C. Uthappa, L. Maitreyi, B. Venkatraman, S. Datta, S. V. R. Sody, B. Majumder, S. Hameed","doi":"10.1016/j.iotech.2023.100663","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100663","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"77 s330","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
104P Bladder-sparing treatment for muscle-invasive bladder carcinoma (MIBC): A single-center, single-arm clinical study of sequential neoadjuvant chemotherapy followed by tislelizumab neoadjuvant immunotherapy 104P 肌肉浸润性膀胱癌(MIBC)的保膀治疗:一项单中心、单臂临床研究,研究内容为序贯新辅助化疗和替舒利珠单抗新辅助免疫疗法
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100576
Y. Zeng
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引用次数: 0
124P Surufatinib plus toripalimab combined with etoposide (E) and cisplatin (P) in patients (pts) with advanced naive small cell lung cancer (SCLC): Updated results of a phase Ib/II trial 124P 舒伐替尼联合托利帕单抗与依托泊苷(E)和顺铂(P)治疗晚期幼稚小细胞肺癌(SCLC)患者(pts):Ib/II期试验的最新结果
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100596
W. Fang, Y. Yang, Y. Huang, Y. Zhao, Y. Zhang, T. Zhou, G. Chen, S. Zhao, Y. Ma, S. Hong, H. Zhao, L. Zhang
{"title":"124P Surufatinib plus toripalimab combined with etoposide (E) and cisplatin (P) in patients (pts) with advanced naive small cell lung cancer (SCLC): Updated results of a phase Ib/II trial","authors":"W. Fang, Y. Yang, Y. Huang, Y. Zhao, Y. Zhang, T. Zhou, G. Chen, S. Zhao, Y. Ma, S. Hong, H. Zhao, L. Zhang","doi":"10.1016/j.iotech.2023.100596","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100596","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"21 38‐39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138624889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
141P An IgE antibody targeting the melanoma-associated chondroitin sulfate proteoglycan 4 141P 一种针对黑色素瘤相关硫酸软骨素蛋白多糖 4 的 IgE 抗体
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100613
L.C.G.F. Palhares, J. Chauhan, M. Grandits, P. Romero-Clavijo, R. Gitsaki-Taylor, S. Mele, S.N. Karagiannis, H. Bax
{"title":"141P An IgE antibody targeting the melanoma-associated chondroitin sulfate proteoglycan 4","authors":"L.C.G.F. Palhares, J. Chauhan, M. Grandits, P. Romero-Clavijo, R. Gitsaki-Taylor, S. Mele, S.N. Karagiannis, H. Bax","doi":"10.1016/j.iotech.2023.100613","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100613","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"24 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138625124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
116TiP Randomized, open-label, phase II study of botensilimab (BOT) alone and in combination with balstilimab (BAL) versus standard-of-care in patients with refractory metastatic colorectal cancer 116TiP 对难治性转移性结直肠癌患者进行的肉毒昔单抗 (BOT) 单独使用和与巴利昔单抗 (BAL) 联合使用与标准疗法对比的随机、开放标签 II 期研究
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100588
E. van Cutsem, M. Fakih, N.H. Segal, B. Johnson, A. Kardosh, A. Philipovskiy, S. Krishnamurthi, P.J. Gold, J. Dekervel, B. L. Schlechter, J. Grossman, M.E. Elez Fernandez, N. Vardiashvili, A.A. Azambuja, C. Eng, M.P. Ducreux, T. André, J. Tabernero, H.J. Lenz, M. Hidalgo
{"title":"116TiP Randomized, open-label, phase II study of botensilimab (BOT) alone and in combination with balstilimab (BAL) versus standard-of-care in patients with refractory metastatic colorectal cancer","authors":"E. van Cutsem, M. Fakih, N.H. Segal, B. Johnson, A. Kardosh, A. Philipovskiy, S. Krishnamurthi, P.J. Gold, J. Dekervel, B. L. Schlechter, J. Grossman, M.E. Elez Fernandez, N. Vardiashvili, A.A. Azambuja, C. Eng, M.P. Ducreux, T. André, J. Tabernero, H.J. Lenz, M. Hidalgo","doi":"10.1016/j.iotech.2023.100588","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100588","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"101 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138609104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
133P Phase I/II study of XTX101: A masked, tumor-activated Fc-enhanced anti-CTLA-4, in patients with advanced solid tumors 133P XTX101 的 I/II 期研究:针对晚期实体瘤患者的掩蔽式肿瘤激活 Fc 增强型抗 CTLA-4
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100605
D. Davar, J.G. Knecht, A. Vandross, C.A. Perez, D.M. Miller, J. Powderly, A. Bessudo, K. Montazeri, M.J. Mooradian, A. Gupta, E. Patel, D. Fantini, S. Paramasivan, D. Crowe, M. Duncan, S. Uptain, K. Luptakova, R. Sullivan
{"title":"133P Phase I/II study of XTX101: A masked, tumor-activated Fc-enhanced anti-CTLA-4, in patients with advanced solid tumors","authors":"D. Davar, J.G. Knecht, A. Vandross, C.A. Perez, D.M. Miller, J. Powderly, A. Bessudo, K. Montazeri, M.J. Mooradian, A. Gupta, E. Patel, D. Fantini, S. Paramasivan, D. Crowe, M. Duncan, S. Uptain, K. Luptakova, R. Sullivan","doi":"10.1016/j.iotech.2023.100605","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100605","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
201P Role of aerobic exercise training on the mitochondrial metabolism and effector function of CD8+ tumor-infiltrating lymphocytes 201P 有氧运动训练对 CD8+ 肿瘤浸润淋巴细胞线粒体代谢和效应功能的作用
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100677
J.D.S. Vieira, V. Voltarelli, M.T. Amano, A.A. Camargo, P.C. Brum
{"title":"201P Role of aerobic exercise training on the mitochondrial metabolism and effector function of CD8+ tumor-infiltrating lymphocytes","authors":"J.D.S. Vieira, V. Voltarelli, M.T. Amano, A.A. Camargo, P.C. Brum","doi":"10.1016/j.iotech.2023.100677","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100677","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
111P Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma compared to patients with advanced solid tumours 111P 与晚期实体瘤患者相比,肝细胞癌患者免疫疗法相关肝损伤的特征和结局
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100583
C. Celsa, G. Cabibbo, T.U. Marron, A. Saeed, M. Pinter, Y-H. Huang, A. Pillai, M. Schoenlein, J. von Felden, P. Galle, M. Kudo, L. Rimassa, A. Singal, H. Chon, W-F. Hsu, L. Brunetti, C. Pinto, M. Bersanelli, A. Cortellini, D. Pinato
{"title":"111P Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma compared to patients with advanced solid tumours","authors":"C. Celsa, G. Cabibbo, T.U. Marron, A. Saeed, M. Pinter, Y-H. Huang, A. Pillai, M. Schoenlein, J. von Felden, P. Galle, M. Kudo, L. Rimassa, A. Singal, H. Chon, W-F. Hsu, L. Brunetti, C. Pinto, M. Bersanelli, A. Cortellini, D. Pinato","doi":"10.1016/j.iotech.2023.100583","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100583","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138617871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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