D. Berz, D. Pinato, M. Barve, J. Pulini, J. Bowman, M.L. Johnson
{"title":"159TiP Two phase I studies assessing the safety and efficacy of the small molecule oral PD-L1 inhibitor INCB099280 in combination with adagrasib (INCB 99280-204 [study 204]) or ipilimumab (INCB 99280-205 [study 205]) in adults with advanced solid tumors","authors":"D. Berz, D. Pinato, M. Barve, J. Pulini, J. Bowman, M.L. Johnson","doi":"10.1016/j.iotech.2023.100670","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100670","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138619374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. M. Di Giacomo, G. Rossi, L. Calabro, A. Pascucci, V. Vegni, E. Simonetti, M. Colucci, M. Valente, G. Gibilisco, F. Frongia, M.F. Lofiego, G. Amato, H.N. Keer, A. Oganesian, D. Chan, D. Giannarelli, M. Ceccarelli, A. Anichini, A. Covre, M. Maio
{"title":"123P A phase II study of nivolumab (N) plus ipilimumab (I) and ASTX727 or N plus I in PD-1/PD-L1 resistant melanoma or NSCLC patients: The run-in phase of the NIBIT Foundation ML1 study","authors":"A. M. Di Giacomo, G. Rossi, L. Calabro, A. Pascucci, V. Vegni, E. Simonetti, M. Colucci, M. Valente, G. Gibilisco, F. Frongia, M.F. Lofiego, G. Amato, H.N. Keer, A. Oganesian, D. Chan, D. Giannarelli, M. Ceccarelli, A. Anichini, A. Covre, M. Maio","doi":"10.1016/j.iotech.2023.100595","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100595","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 69","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rigutto, N. Nunez, J. Kienzler, M. Kirschner, I. Opitz, S. Hiltbrunner, N. Fournier, J. Lourenço, R. Gottardo, B. Becher, A. Curioni-Fontecedro
{"title":"169P High-dimensional analysis of tumor infiltrating immune cells reveals major differences in the tumor immune microenvironments of pleural mesothelioma and lung cancer","authors":"A. Rigutto, N. Nunez, J. Kienzler, M. Kirschner, I. Opitz, S. Hiltbrunner, N. Fournier, J. Lourenço, R. Gottardo, B. Becher, A. Curioni-Fontecedro","doi":"10.1016/j.iotech.2023.100628","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100628","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"62 s233","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138621894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Greil, B. Burtness, S. Laban, I. Brana, R. Mesia Nin, T. Fuereder, Å. Bratland, L. Licitra, T. Rordorf, A. Psyrri, A. Popovtzer, B. Hughes, M. Tahara, J. Lin, B. Gumuscu, N. Lerman, K.J. Harrington
{"title":"106P Treatment sequencing in PD-L1–positive recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC): Exploratory analysis of the phase III KEYNOTE-048 study","authors":"R. Greil, B. Burtness, S. Laban, I. Brana, R. Mesia Nin, T. Fuereder, Å. Bratland, L. Licitra, T. Rordorf, A. Psyrri, A. Popovtzer, B. Hughes, M. Tahara, J. Lin, B. Gumuscu, N. Lerman, K.J. Harrington","doi":"10.1016/j.iotech.2023.100578","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100578","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"167P Lurbinectedin: A DNA minor groove inhibitor launches a multimodal immune response through activation of the cytosolic DNA-sensing cGAS-STING pathway","authors":"T. Sen","doi":"10.1016/j.iotech.2023.100626","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100626","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"113 s429","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Noringriis, M. Donia, L. Bastholt, H. Schmidt, C. Haslund, E. Ellebæk, I-M. Svane
{"title":"109P Prognosis of patients with metastatic melanoma with initial stable disease during treatment with anti-PD-1 monotherapy","authors":"I. Noringriis, M. Donia, L. Bastholt, H. Schmidt, C. Haslund, E. Ellebæk, I-M. Svane","doi":"10.1016/j.iotech.2023.100581","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100581","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"23 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138624270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Yeku, M. Barve, W.W. Tan, J.S. Wang, A. Patnaik, P. Lorusso, A. Naqash, A. Dowlati, S. Fu, M. Gordon, J. Hubbard, S. Kummar, C. Kyriakopoulos, E. Schenk, D. Deegan, L. Liang, Y. Li, L. Reyno, M. Chamberlain, I. Winer
{"title":"126P Evaluation of myeloid targeting agents, PY159 and PY314, in two dose expansion phase Ib trials in platinum-resistant ovarian cancer","authors":"O. Yeku, M. Barve, W.W. Tan, J.S. Wang, A. Patnaik, P. Lorusso, A. Naqash, A. Dowlati, S. Fu, M. Gordon, J. Hubbard, S. Kummar, C. Kyriakopoulos, E. Schenk, D. Deegan, L. Liang, Y. Li, L. Reyno, M. Chamberlain, I. Winer","doi":"10.1016/j.iotech.2023.100598","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100598","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"316 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138625751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Augustine, N. R. Nene, K. Thakkar, D. Qian, E. Fitzsimons, B. Simpson, C. Watkins, C. Swanton, K.R. Litchfield
{"title":"142P Identifying novel immunotherapy targets using machine learning and ex vivo validation","authors":"M. Augustine, N. R. Nene, K. Thakkar, D. Qian, E. Fitzsimons, B. Simpson, C. Watkins, C. Swanton, K.R. Litchfield","doi":"10.1016/j.iotech.2023.100614","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100614","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"13 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Peled, J. Mazieres, D.M. Kowalski, W-S. Lam, M. Hochmair, M. Majem, S.H. Kim, A. C. Blanco, K. Cuppens, I.A. Casarini, O. Bylicki, B. Shim, J.B. Sørensen, M. Gilli, S.H. How, C. Schumann, C. Gonzalez Arenas, T. He, A. Samkari, S. Novello
{"title":"121P MK-7684A (vibostolimab [vibo] plus pembrolizumab [pembro] coformulation) with/without docetaxel in metastatic NSCLC after platinum-chemotherapy (chemo) and immunotherapy","authors":"N. Peled, J. Mazieres, D.M. Kowalski, W-S. Lam, M. Hochmair, M. Majem, S.H. Kim, A. C. Blanco, K. Cuppens, I.A. Casarini, O. Bylicki, B. Shim, J.B. Sørensen, M. Gilli, S.H. How, C. Schumann, C. Gonzalez Arenas, T. He, A. Samkari, S. Novello","doi":"10.1016/j.iotech.2023.100593","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100593","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"37 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Döhrmann, J. Levin, N. Dedeic, A. Almaguer, D. Zuill, E. Abelovski, J. Fortier, Q. Zhao, M. Hernandez, K. Amundson, M. Moniz, H. Chen, D. Panickar, T. Lam, T. Brady, A. Borchardt, J. N. Cole, L. W. Tari
{"title":"144P Discovery of CBO421: A first-in-class drug Fc-conjugate (DFC), targeting CD73 in cancer","authors":"S. Döhrmann, J. Levin, N. Dedeic, A. Almaguer, D. Zuill, E. Abelovski, J. Fortier, Q. Zhao, M. Hernandez, K. Amundson, M. Moniz, H. Chen, D. Panickar, T. Lam, T. Brady, A. Borchardt, J. N. Cole, L. W. Tari","doi":"10.1016/j.iotech.2023.100616","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100616","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"66 s95","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138627247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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