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Immuno-Oncology and Technology最新文献

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156TiP The LUNGVAC-study: A randomized phase II, open-label, multicenter study investigating efficacy and safety of anti-PD-1/PD-L1 treatment +/- UV1 vaccination as first-line treatment in patients with inoperable advanced or metastatic non-small cell lung cancer (NSCLC) 156TiP LUNGVAC 研究：一项随机II期、开放标签、多中心研究，探讨抗PD-1/PD-L1治疗+/-UV1疫苗接种作为无法手术的晚期或转移性非小细胞肺癌（NSCLC）患者一线治疗的有效性和安全性
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100667
E.M. Stensland, I.J.Z. Eide, O.T. Brustugun
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引用次数: 0
204P Effect of STAT6 inhibition as a novel strategy for promoting the induction of potent and stable regulatory T cells for use in colitis therapy 204P STAT6 抑制作为一种新策略对促进诱导用于结肠炎治疗的强效稳定调节性 T 细胞的影响
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100680
S. Leon-Cabrera, F. Perez-Noriega, M.F. Correa Perez, R. Arroyo-Olarte
{"title":"204P Effect of STAT6 inhibition as a novel strategy for promoting the induction of potent and stable regulatory T cells for use in colitis therapy","authors":"S. Leon-Cabrera, F. Perez-Noriega, M.F. Correa Perez, R. Arroyo-Olarte","doi":"10.1016/j.iotech.2023.100680","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100680","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"10 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
134P A phase I study exploring the safety and tolerability of the small molecule PD-L1 inhibitor INCB099318 in select advanced solid tumors 134P 一项探索小分子 PD-L1 抑制剂 INCB099318 在特定晚期实体瘤中安全性和耐受性的 I 期研究
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100606
D. Pinato, U. Banerji, S. Rottey, K. Peltola, J. Yachnin, R. Kristeleit, M. Gutierrez, S. Symeonides, N.L. Jebsen, M. Hoejgaard, W. Edenfield, K.B. Smeland, A. Schiza, L. Ny, V. Ebiana, J. Daniel, J. Pulini, R. Plummer
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引用次数: 0
112P Close cardiovascular monitoring during the early stages of treatment for patients receiving immune checkpoint inhibitors 112P 在接受免疫检查点抑制剂治疗的早期阶段对心血管进行密切监测
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100584
D. Delombaerde, C. Vulsteke, N. Van de Veire, D. Vervloet, V. Moerman, L. van Calster, L. Croes, F. Gremonprez, A.M. De Meulenaere, X. E. Kraemer, K. Wouters, M. Peeters, H. Prenen, J. De Sutter
{"title":"112P Close cardiovascular monitoring during the early stages of treatment for patients receiving immune checkpoint inhibitors","authors":"D. Delombaerde, C. Vulsteke, N. Van de Veire, D. Vervloet, V. Moerman, L. van Calster, L. Croes, F. Gremonprez, A.M. De Meulenaere, X. E. Kraemer, K. Wouters, M. Peeters, H. Prenen, J. De Sutter","doi":"10.1016/j.iotech.2023.100584","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100584","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138612353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
183P Multi-omics investigation reveals cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter through HIF-1α/EMT modulation 183P 多组学研究揭示癌症相关成纤维细胞分泌的 FGF7 可通过调节 HIF-1α/EMT 成为卵巢癌进展的促进因子
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100642
S. Feng
{"title":"183P Multi-omics investigation reveals cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter through HIF-1α/EMT modulation","authors":"S. Feng","doi":"10.1016/j.iotech.2023.100642","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100642","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138621014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
171P Immune landscape and CLEVER-1 expression in hepatoblastoma 171P 肝母细胞瘤中的免疫格局和 CLEVER-1 表达
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100630
V. Väyrynen, K. Eloranta, M. Pihlajoki, J. Lohi, A. Kyrönlahti, M. Hollmén, S. Jalkanen, M. Heikinheimo
{"title":"171P Immune landscape and CLEVER-1 expression in hepatoblastoma","authors":"V. Väyrynen, K. Eloranta, M. Pihlajoki, J. Lohi, A. Kyrönlahti, M. Hollmén, S. Jalkanen, M. Heikinheimo","doi":"10.1016/j.iotech.2023.100630","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100630","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138621246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
187P Local and systemic anti-tumor response during tumor development in an immune privileged site: The case of uveal melanoma 187P 免疫特权部位肿瘤发展过程中的局部和全身抗肿瘤反应：葡萄膜黑色素瘤病例
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100646
F. Lucibello, A.I. Lalanne, A-L. Le Gac, A. Soumare, S. Gardrat, N. Cassoux, G. Pierron, S. Piperno-Neumann, M-H. Stern, M.J. Rodrigues, O. Lantz
{"title":"187P Local and systemic anti-tumor response during tumor development in an immune privileged site: The case of uveal melanoma","authors":"F. Lucibello, A.I. Lalanne, A-L. Le Gac, A. Soumare, S. Gardrat, N. Cassoux, G. Pierron, S. Piperno-Neumann, M-H. Stern, M.J. Rodrigues, O. Lantz","doi":"10.1016/j.iotech.2023.100646","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100646","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
193P Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibit anti-cancer immunity via CCL2 193P 利用抑制性髓系细胞上的 Siglec 受体与ialylated 聚糖结合，通过 CCL2 抑制抗癌免疫力
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100652
R. Wieboldt, E. Carlini, C-W. Lin, A. Börsch, A. Zingg, A. Zippelius, H. Läubli, N. Rodrigues Mantuano
{"title":"193P Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibit anti-cancer immunity via CCL2","authors":"R. Wieboldt, E. Carlini, C-W. Lin, A. Börsch, A. Zingg, A. Zippelius, H. Läubli, N. Rodrigues Mantuano","doi":"10.1016/j.iotech.2023.100652","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100652","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" November","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
146P A novel allosteric oral immunotherapy small molecule modulates adenosine 2a receptor signaling and restores anti-tumor immune responses 146P 一种新型异位口服免疫疗法小分子可调节腺苷 2a 受体信号传导并恢复抗肿瘤免疫反应
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100618
D. Pejoski, C. Suess, A. Gouiller, M. Héritier, M. Boujut, S. Tardy, T. De Smedt, L. Galibert, W. Reith, M. Joerger, C. Toso, T. Kössler, H. Hamed, L. Scapozza
{"title":"146P A novel allosteric oral immunotherapy small molecule modulates adenosine 2a receptor signaling and restores anti-tumor immune responses","authors":"D. Pejoski, C. Suess, A. Gouiller, M. Héritier, M. Boujut, S. Tardy, T. De Smedt, L. Galibert, W. Reith, M. Joerger, C. Toso, T. Kössler, H. Hamed, L. Scapozza","doi":"10.1016/j.iotech.2023.100618","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100618","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
155P A phase I study exploring the safety and tolerability of the small-molecule PD-L1 inhibitor INCB099280 in select advanced solid tumors 155P 一项探索小分子 PD-L1 抑制剂 INCB099280 在特定晚期实体瘤中的安全性和耐受性的 I 期研究
Immuno-Oncology and Technology Pub Date : 2023-12-01 DOI: 10.1016/j.iotech.2023.100666
H. Prenen, T. Lesimple, M. Robert, J. Machiels, B.R. Delafontaine, P. Tomasini, T. Meniawy, N. Kotecki, E. Van Cutsem, S.A. Piha-Paul, M.T. Schweizer, S. Gadgeel, S. Kondo, K. Ouali, Y. Kuboki, J. Daniel, V. Ebiana, J. Howe, S. Spitz, A. Italiano
{"title":"155P A phase I study exploring the safety and tolerability of the small-molecule PD-L1 inhibitor INCB099280 in select advanced solid tumors","authors":"H. Prenen, T. Lesimple, M. Robert, J. Machiels, B.R. Delafontaine, P. Tomasini, T. Meniawy, N. Kotecki, E. Van Cutsem, S.A. Piha-Paul, M.T. Schweizer, S. Gadgeel, S. Kondo, K. Ouali, Y. Kuboki, J. Daniel, V. Ebiana, J. Howe, S. Spitz, A. Italiano","doi":"10.1016/j.iotech.2023.100666","DOIUrl":"https://doi.org/10.1016/j.iotech.2023.100666","url":null,"abstract":"","PeriodicalId":192507,"journal":{"name":"Immuno-Oncology and Technology","volume":" 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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