M. Farage, Angela Stadler, D. Chassard, M. Pelisse
{"title":"A randomized prospective trial of the cutaneous and sensory effects of feminine hygiene wet wipes.","authors":"M. Farage, Angela Stadler, D. Chassard, M. Pelisse","doi":"10.1097/ogx.0b013e3181951a08","DOIUrl":"https://doi.org/10.1097/ogx.0b013e3181951a08","url":null,"abstract":"OBJECTIVE\u0000To assess the effects of feminine hygiene wet wipes on vulvar skin.\u0000\u0000\u0000STUDY DESIGN\u0000An examiner-blind, randomized, prospective clinical trial of prototype wet wipes (treatment group) and dry toilet tissue (comparison group) in 120 premenopausal and 60 postmenopausal women was conducted in which the wipes or toilet tissues were for approximately 28 consecutive days.\u0000\u0000\u0000RESULTS\u0000Use of wet wipes in lieu of toilet tissue caused no significant impact on erythema of the external genitalia. Mean vulvar erythema scores after 28 days of product use were lower than baseline scores for both wipes and toilet tissue. In postmenopausal women, wet wipes were associated with increased labial and perineal skin moisture. A minority of premenopausal participants found skin wetness from wipes less appealing and sometimes associated with slight sensory irritation; however, wet wipes were favored for personal cleansing by postmenopausal women.\u0000\u0000\u0000CONCLUSION\u0000Four weeks of using wet wipes caused negligible clinical effects on vulvar skin irritation and appeared to contribute to skin moisture in postmenopausal women. This subgroup preferred using wet wipes, possibly due to the skin atrophy and dryness that accompany estrogen depletion. An opportunity exists to tailor the lotion level on the wipes m to the genital skin condition and preferences of younger and older Women.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122229265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary carcinoma of the fallopian tube and epithelial ovarian carcinoma: a case-control analysis.","authors":"M. S. Dunn, K. Manahan, J. P. Geisler","doi":"10.1097/01.OGX.0000340773.18375.7B","DOIUrl":"https://doi.org/10.1097/01.OGX.0000340773.18375.7B","url":null,"abstract":"OBJECTIVE\u0000To determine whether differences exist in clinicopathologic variables or survival between women with primary carcinoma of the fallopian tube (PCFT) and with epithelial ovarian carcinoma (EOC).\u0000\u0000\u0000STUDY DESIGN\u0000University of Iowa Hospitals and Clinics (UIHC) tumor board records were analyzed from January 1, 1991, to April 30, 2001. No cases were knowingly excluded. Each case of PCFT was matched with 2 cases of EOC. Controls were the next 2 cases of EOC diagnosed at UIHC after each case of PFTC, with priority given to stage of disease, then histologic grade, followed by histology, with 1 year the limit for obtaining the closest match.\u0000\u0000\u0000RESULTS\u0000Twenty-eight cases of PCFT were found. These were matched with 56 cases of EOC. The mean age at diagnosis was significantly older for women with PCFT (67 years) vs. women with EOC (60 years) (p = 0.005). The was no difference in prediagnosis hormonal contraceptive use (p=0.38), body mass index (p = 0.5) or rate of positive nodes (p = 0.19). Kaplan-Meier analysis revealed no difference in survival between PCFT and EOC (p = 0.5).\u0000\u0000\u0000CONCLUSION\u0000There is no significant difference in clinical parameters or survival between patients with PCFT or EOC when matched for stage, grade and histology.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115138209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Garrett, Elizabeth I. O. Garner, C. Feltmate, D. Goldstein, R. Berkowitz
{"title":"Subsequent pregnancy outcomes in patients with molar pregnancy and persistent gestational trophoblastic neoplasia.","authors":"L. Garrett, Elizabeth I. O. Garner, C. Feltmate, D. Goldstein, R. Berkowitz","doi":"10.1097/01.OGX.0000335639.50781.79","DOIUrl":"https://doi.org/10.1097/01.OGX.0000335639.50781.79","url":null,"abstract":"OBJECTIVE\u0000To evaluate the subsequent reproductive outcomes in patients with complete and partial molar pregnancy and gestational trophoblastic neoplasia (GTN) at the New England trophoblastic Disease Center between June 1, 1965, and December 31, 2007.\u0000\u0000\u0000STUDY DESIGN\u0000Questionnaires regarding subsequent pregnancies were mailed to all patients with current mailing addresses at the New England Trophoblastic Disease Center.\u0000\u0000\u0000RESULTS\u0000The subsequent reproductive outcomes in patients with complete and partial molar pregnancies and persistent GTN were in general the same as those in the general population. However, after an episode of molar pregnancy the incidence of molar pregnancy in a later gestation was approximately 1%. Additionally, after successful chemotherapy for GTN, the incidence of stillbirth was 1.4% in later pregnancies.\u0000\u0000\u0000CONCLUSION\u0000Patients with molar pregnancies and GTN should be reassured that they can in general expect a normal future reproductive outcome.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133178195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First-trimester biochemistry and outcomes in twin pregnancy.","authors":"S. Chasen, S. Martinucci, S. Perni, R. Kalish","doi":"10.1016/J.AJOG.2007.10.276","DOIUrl":"https://doi.org/10.1016/J.AJOG.2007.10.276","url":null,"abstract":"","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133155019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Morrison, Snehal T. Patel, Wendy Watson, Qasim R Zaidi, A. Mangione, T. Goss
{"title":"Assessment of the prevalence and impact of anemia on women hospitalized for gynecologic conditions associated with heavy uterine bleeding.","authors":"John Morrison, Snehal T. Patel, Wendy Watson, Qasim R Zaidi, A. Mangione, T. Goss","doi":"10.1182/BLOOD.V110.11.5167.5167","DOIUrl":"https://doi.org/10.1182/BLOOD.V110.11.5167.5167","url":null,"abstract":"OBJECTIVE\u0000Women with heavy uterine bleeding often are untreated or inadequately treated for anemia. This study was conducted to estimate the prevalence and impact of anemia in women hospitalized for gynecologic conditions associated with heavy uterine bleeding.\u0000\u0000\u0000STUDY DESIGN\u0000The largest all-payer inpatient care database, the Healthcare Cost and Utilization Project's 2003 Nationwide Inpatient Sample, was queried using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes to identify and group women with gynecologic diagnoses associated with heavy uterine bleeding into 2 categories: those with or without anemia. Groups were evaluated for demographic characteristics, medical resource utilization and hospitalization costs using descriptive statistics.\u0000\u0000\u0000RESULTS\u0000More than 25% of the estimated 300,589 women in the study had a diagnosis of anemia. Compared to patients without a diagnosis of anemia, those with an anemia diagnosis were more likely to have a blood transfusion (24% vs. 0.7%, p<0.0001), an emergency department admission (26.8% vs. 3.2%, p<0.0001) and higher hospitalization costs ($5,631 vs. $5,101, p <0.0001).\u0000\u0000\u0000CONCLUSIONS\u0000Anemia and blood transfusions are common in women hospitalized for gynecologic conditions associated with heavy uterine bleeding. Greater patient and provider awareness of the prevalence and burden associated with anemia may increase opportunities to reduce blood transfusions and improve general health status and quality of life in this patient population.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122960707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uterosacral colpopexy at the time of vaginal hysterectomy: comparison of laparoscopic and vaginal approaches.","authors":"C. Rardin, E. Erekson, V. Sung, R. Ward, D. Myers","doi":"10.1016/J.JMIG.2007.08.072","DOIUrl":"https://doi.org/10.1016/J.JMIG.2007.08.072","url":null,"abstract":"","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126211240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Del Priore, J. Malanowska-Stega, S. Shalaby, S. Richman
{"title":"A pilot safety and tolerability study of a nonhormonal vaginal contraceptive ring.","authors":"G. Del Priore, J. Malanowska-Stega, S. Shalaby, S. Richman","doi":"10.1016/J.FERTNSTERT.2007.07.877","DOIUrl":"https://doi.org/10.1016/J.FERTNSTERT.2007.07.877","url":null,"abstract":"","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"514 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133356161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of nonmedical treatments by infertility patients.","authors":"J. Schaffir, A. McGee, E. Kennard","doi":"10.1016/J.FERTNSTERT.2007.07.912","DOIUrl":"https://doi.org/10.1016/J.FERTNSTERT.2007.07.912","url":null,"abstract":"","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122933936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Martin-Johnston, M. Uhler, H. Grotjan, A. Lifchez, J. Nani, A. Beltsos
{"title":"Lower chance of pregnancy with repeated cycles with in vitro fertilization.","authors":"M. Martin-Johnston, M. Uhler, H. Grotjan, A. Lifchez, J. Nani, A. Beltsos","doi":"10.1016/J.FERTNSTERT.2006.07.485","DOIUrl":"https://doi.org/10.1016/J.FERTNSTERT.2006.07.485","url":null,"abstract":"","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124006838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Desimone, M. Crisp, F. Ueland, P. DePriest, J. van Nagell, S. Lele, S. Modesitt
{"title":"Concordance of gross surgical and final fixed margins in vulvar intraepithelial neoplasia 3 and vulvar cancer.","authors":"C. Desimone, M. Crisp, F. Ueland, P. DePriest, J. van Nagell, S. Lele, S. Modesitt","doi":"10.1097/01.ogx.0000248800.62038.4e","DOIUrl":"https://doi.org/10.1097/01.ogx.0000248800.62038.4e","url":null,"abstract":"OBJECTIVE\u0000To prospectively evaluate the concordance of initial surgical vulvar margins and final fixed margins and to determine the amount of microscopic pathology of grossly negative margins in women with vulvar intraepithelial neoplasia (VIN) 3 or vulvar carcinoma.\u0000\u0000\u0000STUDY DESIGN\u0000Women with VIN 3 or vulvar carcinoma undergoing surgical excision were identified. Prior to excision, acetic acid was used to highlight the lesions, and 2 sutures were placed, 1 at the edge of gross disease and another 1 cm distal from the first. After specimen removal and fixation, the distance between sutures and microscopic involvement of VIN was determined.\u0000\u0000\u0000RESULTS\u0000Twenty-seven women were enrolled; however, only 19 had final fixed specimens that could be accurately measured. The median fixed distance of the vulvar margin was 0.85 cm (mean, 0.83; SD, 0.19) as compared to the gross, 1-cm margin (p = 0.001). Three subjects (16%) had microscopic involvement by VIN 3 in the grossly negative epithelium between the 2 sutures, but none had a positive peripheral margin.\u0000\u0000\u0000CONCLUSION\u0000The gross surgical margin after vulvar resection is reduced by 15% when measured in its final fixed state, and a grossly negative 1-cm margin will seldom harbor significant disease.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"2017 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117162963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}