{"title":"Hysteroscopic cervical cannulation under ultrasound guidance. A case report.","authors":"V. T. Goudas, D. Session","doi":"10.1177/875647939901500122","DOIUrl":"https://doi.org/10.1177/875647939901500122","url":null,"abstract":"BACKGROUND\u0000Ultrasound guidance has been recommended for various operative hysteroscopic procedures as an alternative to laparoscopic guidance. Ultrasound is noninvasive and may decrease the incidence of uterine perforation.\u0000\u0000\u0000CASE\u0000A 30-year-old nulligravida presented for the evaluation of amenorrhea of two months' duration. She was diagnosed as having cervical obstruction and underwent operative hysteroscopy with cervical cannulation under ultrasound guidance. The patient's menstrual flow returned at the appropriate time without dysmenorrhea.\u0000\u0000\u0000CONCLUSION\u0000Ultrasound guidance during hysteroscopy assisted in the proper orientation and position of the hysteroscope at the time of cannulation, potentially minimizing the risk of uterine perforation.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126030480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Joura, H. Zeisler, A. Lösch, M. Sator, S. Müllauer-Ertl
{"title":"Differentiating vulvar intraepithelial neoplasia from nonneoplastic epithelial disorders. The toluidine blue test.","authors":"E. Joura, H. Zeisler, A. Lösch, M. Sator, S. Müllauer-Ertl","doi":"10.1097/00006254-199901000-00015","DOIUrl":"https://doi.org/10.1097/00006254-199901000-00015","url":null,"abstract":"OBJECTIVE\u0000To determine the effectiveness of the toluidine blue test in the differentiation of vulvar intraepithelial neoplasia (VIN) and nonneoplastic epithelial disorders (NNEDs).\u0000\u0000\u0000STUDY DESIGN\u0000This retrospective clinical study included all women with VIN (n = 24) and NNED (n = 72) referred to a vulvar clinic at a university hospital during a two-year period. Vulvoscopy, staining of vulvar epithelium with 1% toluidine blue and punch biopsy were performed.\u0000\u0000\u0000RESULTS\u0000Vulvar epithelium demonstrated toluidine blue staining in 100% of the patients with VIN 3, in 83% of women with VIN 1-2, in 50% of the women with squamous cell hyperplasia and in 10% of the women with lichen sclerosus. The differences in staining between the groups were statistically significant (P < .001). The sensitivity of toluidine blue staining for the detection of VIN was 92%; the negative predictive value 96% in teh investigated cohort. The specificity for strong staining was 88%.\u0000\u0000\u0000CONCLUSION\u0000The toluidine blue test is an inexpensive and reliable method of separating VIN from hyperplastic NNED areas and choosing a biopsy site on the vulva.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129709915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"All-fours maneuver for reducing shoulder dystocia during labor.","authors":"J. Bruner, S. Drummond, A. Meenan, I. M. Gaskin","doi":"10.1097/00006254-199901000-00009","DOIUrl":"https://doi.org/10.1097/00006254-199901000-00009","url":null,"abstract":"OBJECTIVE\u0000To report on a large amount of clinical experience with shoulder dystocia managed primarily with the all-fours maneuver.\u0000\u0000\u0000STUDY DESIGN\u0000The all-fours maneuver consists of moving the laboring patient to her hands and knees. Eighty-two consecutive cases of shoulder dystocia managed with this technique were reported to a registry through January 1996.\u0000\u0000\u0000RESULTS\u0000The incidence of shoulder dystocia was 1.8%, and half of the newborns weighed > or = 4,000 g. Sixty-eight women (83%) delivered without the need for any additional maneuvers. The mean diagnosis-to-delivery interval was 2.3 +/- 1.0 (SD) minutes (range, 1-6). No maternal or perinatal mortality occurred. Morbidity was noted in only four deliveries: a single case of postpartum hemorrhage that did not require transfusion (maternal morbidity, 1.2%), one infant with a fractured humerus and three with low Apgar scores (neonatal morbidity, 4.9%). All morbidity occurred in cases with a birth weight > 4,500 g (P = .0009).\u0000\u0000\u0000CONCLUSION\u0000The all-fours maneuver appears to be a rapid, safe and effective technique for reducing shoulder dystocia in laboring women.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121348766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient anxiety during gynecologic examinations. Behavioral indicators.","authors":"D. Reddy, S. Wasserman","doi":"10.1097/00128360-199804000-00016","DOIUrl":"https://doi.org/10.1097/00128360-199804000-00016","url":null,"abstract":"OBJECTIVE\u0000To identify behaviors that indicate anxiety during a gynecologic examination.\u0000\u0000\u0000STUDY DESIGN\u0000Five hundred twenty-two women visiting a private obstetrician/gynecologist's office completed the A-State scale of the State-Trait Anxiety Inventory and specific questions about their first pelvic examination and experiences with health practitioners performing subsequent gynecologic examinations. In addition, the hand placement a woman exhibited as the speculum was inserted was recorded, as were the reasons for her visit, reports of any symptoms, performance of any special procedures (e.g., colposcopy) and whether the pelvic examination was her first.\u0000\u0000\u0000RESULTS\u0000Five behaviors observed during speculum insertion--holding hands/eyes covered or shut, hands on shoulders, hands covering pelvis, hands on legs, hands holding table--indicated increased anxiety. Together these behaviors were exhibited by one of every four patients and were found to be associated with high levels of anxiety. Greater anxiety was related to colposcopy, a less positive first pelvic examination experience, overall less positive experiences with examiners and performance of the first gynecologic examination at the present visit.\u0000\u0000\u0000CONCLUSION\u0000Easily recognizable behaviors reflecting high anxiety in gynecologic patients were identified. Upon recognizing these behaviors, examiners can take necessary measures to reduce patient anxiety and prevent delays in and avoidance of gynecologic examinations.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114303700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The genetics of endometriosis.","authors":"S. Kennedy","doi":"10.1201/B14235-5","DOIUrl":"https://doi.org/10.1201/B14235-5","url":null,"abstract":"Endometriosis is probably a complex trait, like diabetes, hypertension or asthma, which implies that the disease is caused by an interaction between multiple genes and the environment. This paper reviews the evidence, in both human and nonhuman primates, that supports the theory of a genetic basis to endometriosis. The OXEGENE study, which aims to identify susceptibility genes in endometriosis through linkage analysis, is also described. DNA is being collected from families containing at least two sisters with surgically confirmed revised American Fertility Society stage III and IV disease to carry out a genome-wide search for susceptibility genes. Candidate genes involved in galactose metabolism and dioxin detoxification are also being analyzed. The identification of genes conferring susceptibility to endometriosis may lead to a better understanding of disease etiology and, in time, improved therapeutic strategies and diagnostic methods.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130826699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Newlands, Mark Bower, L. Holden, D. Short, M. Seckl, G. Rustin, Richard H. J. Begent, K. D. Bagshawe
{"title":"Management of resistant gestational trophoblastic tumors.","authors":"E. Newlands, Mark Bower, L. Holden, D. Short, M. Seckl, G. Rustin, Richard H. J. Begent, K. D. Bagshawe","doi":"10.1097/00006254-199807000-00015","DOIUrl":"https://doi.org/10.1097/00006254-199807000-00015","url":null,"abstract":"OBJECTIVE\u0000To analyze the causes of therapeutic success and failure in the management of patients with high-risk gestational trophoblastic tumors (GTTs).\u0000\u0000\u0000STUDY DESIGN\u0000Analysis of 272 consecutive high-risk patients treated at the trophoblastic disease center at the Charing Cross Hospital between 1979 and 1995.\u0000\u0000\u0000RESULTS\u0000EMA (etoposide, methotrexate, actinomycin D)/CO (cyclophosphamide, vincristine) chemotherapy is our treatment of choice for patients with high-risk GTT. In 272 consecutive patients the cumulative five-year survival was 86.2% (95% confidence interval, 81.9-90.5%). No deaths occurred from GTT more than two years after the start of treatment. In patients whose disease became resistant to EMA/CO or relapsed after receiving EMA/CO, the majority (70%) could be salvaged with further chemotherapy (usually with the EP (etoposide, cisplatin)/EMA chemotherapy with or without surgery. Multivariate analysis identified the following adverse prognostic factors: presence of liver metastases (P < .0001), prolonged interval from antecedent pregnancy (P < .0001), presence of brain metastases (P = .0008) and term delivery of antecedent pregnancy (P = .045). Intensive chemotherapy for treating high-risk GTT carries a small risk of inducing second malignancies, and two patients developed acute myeloid leukemia, 2 cervical malignancy and 1 gastric adenocarcinoma after receiving EMA/CO chemotherapy.\u0000\u0000\u0000CONCLUSION\u0000EMA/CO is an effective and well-tolerated regimen for high-risk GTT. Salvage chemotherapy with EP/EMA is effective in the majority of patients whose disease is resistant to EMA/CO and should be combined with surgery when the dominant site of resistant disease is known. Major adverse prognostic variables have been identified, and patients with combinations of these factors should be considered for innovative therapeutic approaches from the outset.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131592529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathleen Berkowitz, Carolina Reyes, Peyman Saadat, Siri L. Kjos
{"title":"Fetal lung maturation. Comparison of biochemical indices in gestational diabetic and nondiabetic pregnancies.","authors":"Kathleen Berkowitz, Carolina Reyes, Peyman Saadat, Siri L. Kjos","doi":"10.1097/00006254-199808000-00005","DOIUrl":"https://doi.org/10.1097/00006254-199808000-00005","url":null,"abstract":"OBJECTIVE\u0000To compare the biochemical maturation of the components of the lung profile according to gestational age between reliably dated gestational diabetic and nondiabetic pregnancies.\u0000\u0000\u0000STUDY DESIGN\u0000Lung maturation was compared in reliably dated pregnancies in 501 gestational diabetic women and 561 nondiabetic women. Lecithin/sphingomyelin ratio (L/S) and phosphatidylglycerol (PG) were evaluated by analysis of variance according to the presence or absence of diabetes and weeks of gestational age. The effect of gestational diabetes on fetal lung maturation was determined by analysis of variance.\u0000\u0000\u0000RESULTS\u0000The gestational diabetic group had no clinical or statistical differences in L/S ratios as compared to the nondiabetic patients at any gestational age. There were no differences in mean percent PG between the diabetic and nondiabetic groups at any gestational age. By 37 completed weeks, 86% of the L/S ratios and 78% of the PG values were mature in the diabetic group as compared to 80% of the L/S ratios and 78% of the PG values in the control group (P = .33 and .43, respectively).\u0000\u0000\u0000CONCLUSION\u0000In reliably dated gestational diabetic pregnancies, biochemical maturation of the fetal lung strongly correlates with gestational age and does not appear to be significantly delayed when compared to a nondiabetic control group.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123259173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Terbutaline pump tocolysis in high-order multiple gestation.","authors":"J. Elliott, M. J. Flynn, E. Kaemmerer, T. Radin","doi":"10.1097/00006254-199808000-00004","DOIUrl":"https://doi.org/10.1097/00006254-199808000-00004","url":null,"abstract":"OBJECTIVE\u0000To review terbutaline pump tocolytic therapy as part of the management of high-order multiple gestations (triplet and quadruplet pregnancies).\u0000\u0000\u0000STUDY DESIGN\u0000We performed a retrospective review of the medical records of triplet and quadruplet pregnancies cared for by Phoenix Perinatal Associates from August 1988 to January 1992 in whom terbutaline pump tocolysis was administered.\u0000\u0000\u0000RESULTS\u0000The study group consisted of 15 triplet pregnancies and 6 quadruplet pregnancies. The 15 patients with triplets delivered at a mean (+/- SD) gestational age of 33.0 +/- 1.9 weeks. The six patients with quadruplets delivered at 33.0 +/- 1.3 weeks. Only 2 of 15 (13%) of the triplets and 1 of 6 (17%) of the quadruplets were delivered for tocolytic failure.\u0000\u0000\u0000CONCLUSION\u0000Terbutaline pump tocolysis provides safe and effective tocolytic therapy in a select group of high-order multifetal gestations.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127223477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood cultures in febrile patients after hysterectomy. Cost-effectiveness.","authors":"E. Swisher, B. Kahleifeh, J. Pohl","doi":"10.1097/00006254-199801000-00012","DOIUrl":"https://doi.org/10.1097/00006254-199801000-00012","url":null,"abstract":"OBJECTIVE\u0000To determine the impact and cost-effectiveness of blood cultures in patients with febrile morbidity following vaginal or abdominal hysterectomy.\u0000\u0000\u0000STUDY DESIGN\u0000The charts of 192 abdominal and 150 vaginal hysterectomy cases performed at Walter Reed Army Medical Center for benign disease between June 1992 and June 1995 were retrospectively analyzed for postoperative febrile morbidity, fever evaluation, blood culture results, management and clinical course.\u0000\u0000\u0000RESULTS\u0000Of the 342 hysterectomy cases reviewed, 46 (24%) abdominal and 16 (10.7%) vaginal hysterectomies had fever evaluations that included aerobic and anaerobic blood cultures. There were no blood cultures documenting bacteremia in the abdominal or vaginal hysterectomy patients evaluated for postoperative febrile morbidity. Two patients with positive blood cultures had preoperative infections and were eliminated from statistical analysis. Adherence to the definition of febrile morbidity eliminated another 19 (30.6%) of the 62 febrile patients phlebotomized for blood cultures.\u0000\u0000\u0000CONCLUSION\u0000Blood cultures in the routine patient following vaginal or abdominal hysterectomy did not alter management and were not cost-effective. Blood cultures may be appropriate for febrile patients with preoperative, intraoperative and postoperative risk factors for bacteremia.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129922082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T J Schermerhorn, J. Hodge, A. Saltzman, T. Hackett, H. Sprance, T. Harrison
{"title":"Clinicopathologic variables predictive of residual dysplasia after cervical conization.","authors":"T J Schermerhorn, J. Hodge, A. Saltzman, T. Hackett, H. Sprance, T. Harrison","doi":"10.1097/00128360-199710000-00013","DOIUrl":"https://doi.org/10.1097/00128360-199710000-00013","url":null,"abstract":"OBJECTIVE\u0000To evaluate the clinicopathologic variables that are important for predicting residual dysplasia after cervical conization or the loop electroexcisional procedure.\u0000\u0000\u0000STUDY DESIGN\u0000A retrospective review of 80 cases was performed on patients with squamous dysplasia in the conization specimen, endocervical curettage (ECC) performed immediately after resection, margin status reported by the pathologist and adequate postprocedure follow-up.\u0000\u0000\u0000RESULTS\u0000Twelve patients had residual dysplasia. No case progressed to invasive carcinoma. A multivariate analysis was performed with presence or absence of residual dysplasia as the dependent variable and patient age, type of procedure (cold knife conization or loop excision), grade of dysplasia, margin status and ECC status as independent variables. Margin status was the strongest predictor of residual disease, followed by ECC status. Patient age had a minimal association with persistence. Of the 12 patients with residual dysplasia, 11 had a positive margin, and 8 had a positive ECC. Only 38% of patients with a positive margin had residual disease, but 67% with a positive margin and ECC had residual dysplasia.\u0000\u0000\u0000CONCLUSION\u0000Margin status and ECC are useful in predicting residual dysplasia after conization.","PeriodicalId":192418,"journal":{"name":"The Journal of reproductive medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116124934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}