Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology最新文献_第5页

[Morphological changes in sebaceous glands with aging in human males]. [人类男性皮脂腺随年龄增长的形态学变化]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-03-01

K Ikeda

引用次数: 0

[Delusions of parasitosis--report of 94 cases]. 【寄生虫病妄想94例报告】。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-03-01

N Ohtaki

引用次数: 0

[Normolipemic xanthoma developed on alopecia lesion on a SLE patient--histological study]. [SLE患者秃发病变上发生的正常血脂性黄色瘤-组织学研究]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-03-01

H Arai, A Ito, A Hashimoto, H Eto, S Nishiyama

{"title":"[Normolipemic xanthoma developed on alopecia lesion on a SLE patient--histological study].","authors":"H Arai, A Ito, A Hashimoto, H Eto, S Nishiyama","doi":"","DOIUrl":"","url":null,"abstract":"A 30-year-old SLE patient developed a xanthoma on her alopecia lesion. Histological examination showed typical lupus changes including immunofluorescence stainings. In addition, there were numerous xanthoma cells existed through the dermis, interlobular spaces of subcutaneous fat tissue, perivascular areas of small blood vessels, and subendothelial spaces and inside of intraluminal thrombosis of subcutaneous small arteries. These xanthoma cells contained granular materials in their cytoplasm. Histochemically, these materials are diastase resistant P.A.S. (+), immunoglobulin (+), Sudan BB (+), Sudan III (+), Nile blue (pinkish red), and yellowish orange autofluorescence suggesting that they are lipofuscin or lipid peroxidation products. Further histological findings showed destruction of sebaceus glands and peri-glandular++ infiltration of lymphocytes and histiocytes. These histiocytes contained phagocytic neutral lipid droplets in their cytoplasm. Very small lipid peroxides were also seen on surface and/or cytoplasm of infiltrating lymphocytes existing not only peri-lobular area but also intraluminal area of blood vessels. The marker profile of these infiltrating lymphocytes are B-cell predominant admixed with some CD8(+) T-cells. These data suggest that the mechanism of developing xanthoma is initiated by immune-complex deposition on basal lamina of sebaceus glands, followed by destruction of sebaceus glands by lympho-histiocytic cells infiltration with some antigen presenting and/or effector cells, and finally xanthoma cells were developed by phagocytosis of lipid peroxides caused by macrophage-derived oxygen radicals. Interestingly, our data suggest that the lipid peroxides, which may act as photosensitizer, may leave the skin and may enter the small vessels carried by lymphocytes. Furthermore the xanthoma cells may also enter the circulation through the small arteries.","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13047640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Adult dermatomyositis with angiopathy and cecum perforation]. 成人皮肌炎伴血管病变和盲肠穿孔。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-03-01

M Niizawa, O Maie, Y Asanuma, T Saito

{"title":"[Adult dermatomyositis with angiopathy and cecum perforation].","authors":"M Niizawa, O Maie, Y Asanuma, T Saito","doi":"","DOIUrl":"","url":null,"abstract":"This previously healthy 43-year-old man was admitted to our hospital with a history of rash, dysphagia and severe myalgia for two months. Physical examination showed prominent edema and erythema over the face and the chest, scattered ulcerations on the trunk, and muscle atrophy most prominent proximally. Serum levels of muscle enzymes were remarkably increased. Two weeks of oral prednisolone therapy (40 mg/day) was not effective, and betamethasone intravenous pulse therapy (3 x 1000 mg) was followed by slight clinical improvement. However, 12 days after pulse therapy, he complained abdominal pain on the right lower quadrant. The surgical findings included peritonitis due to single perforation of the cecum. After operation, cyclosporine therapy was added and over the next 14 month a considerable clinical improvement was noted. Prednisolone was reduced from 80 mg to 10 mg daily. Biopsy specimens from ulcerated+ skin and perforated cecum showed prominent vascular abnormalities: arterial and venous intimal hyperplasia, occlusion of vessels by fibrin thrombi, and lymphocytic infiltration which affected veins of all sizes. The evidence strongly suggests that both skin ulcers and cecum perforation were caused by vasculitis and occlusion of vessels, which often seen in childhood dermatomyositis.","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13047642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Two cases of transient acantholytic dermatosis--with the analysis of 20 cases reported in Japan]. 【一过性棘囊性皮肤病2例——附日本20例报告分析】。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-03-01

N Kato, K Furuya

引用次数: 0

[Localization of HTLV-I-associated antigens in adult T cell leukemia cells and HTLV-I-infected cell line cells]. [htlv - 1相关抗原在成人T细胞白血病细胞和htlv - 1感染细胞系细胞中的定位]

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-02-01

F X Jin, K Iwatsuki, D Horiguchi, K Sugaya, F Nakayama, M Koide, M Takigawa, M Yamada

{"title":"[Localization of HTLV-I-associated antigens in adult T cell leukemia cells and HTLV-I-infected cell line cells].","authors":"F X Jin, K Iwatsuki, D Horiguchi, K Sugaya, F Nakayama, M Koide, M Takigawa, M Yamada","doi":"","DOIUrl":"","url":null,"abstract":"Localization of HTLV-I-associated antigens was studied in adult T cell leukemia (ATL) cells and HTLV-I-infected cell line cells using monoclonal and human polyclonal antibodies against the viral-related antigens. Two monoclonal antibodies that we obtained by hybridoma technique reacted with HTLV-I-virus core antigens, P19 and P24, respectively. Human anti-HTLV-I-antibodies, which were purified from sera from ATL patients reacted with not only HTLV-I virus particles but also their precursors located in the cytoplasm. In tumor cells freshly isolated from ATL patients, no expression of the virus antigens was observed. When the cells were cultured for several days, the virus antigens were defined in about 3-5% of the cultured cells by the monoclonal antibodies, and in 5-10% by the purified human anti-HTLV-I antibodies. Addition of 5-iodo-2'-deoxyuridine to the culture inhibited cell growth, and at the same time, increased the percentage of the virus antigen-positive cells. Established HTLV-I-infected cell lines showed different cytological profiles from the original ATL cells in the viral replication and morphology.","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13228320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Increased corneocyte surface area in the diabetic skin]. [糖尿病皮肤角质细胞表面积增加]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-02-01

Y Yajima, H Sueki, R Fujisawa

引用次数: 0

[Expression of blood group-related antigens Lewis A, Lewis B, CA 19-9, and sialyl SSEA-1 in normal human skin in comparison with the patient's blood type]. [血型相关抗原Lewis A、Lewis B、CA 19-9和唾液SSEA-1在正常人皮肤中的表达与患者血型的比较]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-02-01

S Hirai, T Kageshita, T Nakamura, A Yoshii, T Kimura, T Arao

引用次数: 0

[Immunohistochemical alterations in basement membrane components in skin cancer]. [皮肤癌基底膜成分的免疫组化改变]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-02-01

K Oguro

引用次数: 0

[The titers and complement-activating abilities of anticentromere antibody in systemic sclerosis, other connective tissue diseases, and other related conditions]. [抗着丝粒抗体在系统性硬化症、其他结缔组织疾病和其他相关疾病中的滴度和补体激活能力]。

Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology Pub Date : 1991-02-01

S Sato, K Takehara, Y Ishibashi

{"title":"[The titers and complement-activating abilities of anticentromere antibody in systemic sclerosis, other connective tissue diseases, and other related conditions].","authors":"S Sato, K Takehara, Y Ishibashi","doi":"","DOIUrl":"","url":null,"abstract":"The anticentromere antibody is considered to be a useful serologic marker for the CREST syndrome. But this antibody also appears in other related conditions less frequently. We classified 29 patients with anticentromere antibodies into 3 groups: (1) 16 patients with systemic sclerosis or Raynaud's phenomenon alone; (2) 7 patients with other connective tissue diseases; (3) 6 patients with other conditions. Ig class reactivities and complement-fixing abilities of anticentromere antibody were measured by the indirect immunofluorescence test. The whole Ig titers were high (1025 or more) in all patients belonging to group 1. However, the properdin-fixing anticentromere antibody titers of these patients were relatively low (256 or less). In contrast, the patients in group 2 and 3 were shown to have higher C3- and properdin-activating abilities which were determined by the ratios of the titers of C3- and properdin-fixing anticentromere antibody to the IgG titers although the whole Ig titers of these patients were widely distributed. These data suggest that the patients who have low whole Ig titers and/or high properdin-fixing titers do not belong to the scleroderma spectrum and that the patients without clinical features of scleroderma have high C3- and properdin-activating abilities.","PeriodicalId":19167,"journal":{"name":"Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13228321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0