Neirofiziologiia = Neurophysiology最新文献

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[Identification of cholinoreceptors on the soma of RPa3 and LPa3 neurons in Helix lucorum]. [荧光螺旋RPa3和LPa3神经元胞体上胆碱受体的鉴定]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
A S Pivovarov, E I Drozdova
{"title":"[Identification of cholinoreceptors on the soma of RPa3 and LPa3 neurons in Helix lucorum].","authors":"A S Pivovarov,&nbsp;E I Drozdova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Selective cholinomimetics and cholinolytics were employed to identify cholinoreceptors on the somatic membrane in Helix lucorum RPa3 and LPa3 neurons using recording of transmembrane ionic currents. Agonists of nicotinic and muscarinic cholinoreceptors evoked reversible activation and following nonreversible inhibition of receptors (except carbamylcholine). Selective cholinomimetics were connected with the same membrane sites that were activated by acetylcholine. Nicotinic and muscarinic cholinolytics decreased the amplitude of inward current induced by acetylcholine (scopolamine and platyphylline had no effect). It is concluded that somatic membrane of RPa3 and LPa3 Helix neurons contains nicotinic and muscarinic cholinoreceptors. These receptors have several pharmacological peculiarities as compared with those of the vertebrates. Muscarinic cholinoreceptors of RPa3 and LPa3 neurons must be included into a special subtype that differs from well-known M1 and M2 subtypes.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 1","pages":"77-86"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12751957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efferent potential-dependent ionic currents developing in frog myoblast culture]. [青蛙成肌细胞培养中产生的依赖电位的离子电流]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
V I Luk'ianenko, I E Katina, G A Nasledov, A V Lonskiĭ
{"title":"[Efferent potential-dependent ionic currents developing in frog myoblast culture].","authors":"V I Luk'ianenko,&nbsp;I E Katina,&nbsp;G A Nasledov,&nbsp;A V Lonskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Variety of outward voltage-dependent currents in cultured frog myoblasts were registered by means of whole cell voltage clamp. Six types of potassium currents (Ik) which reach the peak value (-10 mV) in 5, 12, 20, 30, 50 ms (fast) and do not reach the maximum in 7 s (slow) were established. High sensitivity to low temperature (+5 degrees) was shown for channels of very fast and of slow non-inactivated Ik. The assumption is made that some of Ik--5, 20 and 30 ms to peak are especially characteristic of myoblasts fusion stage.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 1","pages":"109-13"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12752102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of the quantal composition, membrane potential and cholinoreceptor density on the temporal flow of the end plate current in the rat under conditions of acetylcholinesterase inhibition]. [量子组成、膜电位和胆碱受体密度对乙酰胆碱酯酶抑制条件下大鼠端板电流时间流动的影响]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
R A Giniatullin, A B Shvetsov
{"title":"[Effect of the quantal composition, membrane potential and cholinoreceptor density on the temporal flow of the end plate current in the rat under conditions of acetylcholinesterase inhibition].","authors":"R A Giniatullin,&nbsp;A B Shvetsov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The factors determining the decay of multiquantal end plate currents (EPC) were studied in the diaphragm muscle of rat by the comparison of EPC and miniature EPC (MEPC) amplitude--temporal characteristics. The decay of EPC (quantal content 25-100) was 1.2 times slower than the decay of MEPC when AChE was active. The AChE inhibition by armine or neostigmine made this difference 10-100 times higher. In most synapses the decay of multiquantal EPC can be approximated by a sum of two or three exponents. It depended on the quantal content and 3-exponential EPC could be transformed in 2-exponential and later to monoexponential ones if increasing concentration of magnesium ions. A slow component of EPCs (but not of MEPC) decay was highly sensitive to concentration of magnesium ions and had 3 times higher dependence of the membrane potential value than that one of MEPC. The irreversible blocking of receptors by alpha-bungarotoxin (alpha-BuTX) accelerated the decay of MEPC but the decay of multiquantal EPC changed in two phases: it was prolonged at the beginning of alpha-BuTX action followed by its acceleration, but never the time of the decay of EPC had achieved the apparent open time of ACh-activated ionic channels. It is suggested that during the multiquantal EPC generation not only the synchronization of opening but the kinetic of ACh-activated channels is changed, probably by blocking of this channels by high concentrations of endogenous ACh.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 3","pages":"269-79"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12682507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of the vibrostimulation frequency on skin mechanoreceptors innervated with Abeta-, Adelta- and C-fibers]. [振动刺激频率对β -、α -和c -纤维支配的皮肤机械感受器的影响]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
A V Zeveke, E D Efes
{"title":"[Effect of the vibrostimulation frequency on skin mechanoreceptors innervated with Abeta-, Adelta- and C-fibers].","authors":"A V Zeveke,&nbsp;E D Efes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vibrational stimulation of cat's skin by the frequencies of 10, 30 and 50 per second evoked response of mechanoreceptors innervated with A beta and A delta-fibers, responding to each vibration stimulus. The higher vibrostimulation frequency, the more distinct changes appear in the \"on\"--and \"off\"--responses which are caused by a decreasing number of pulses for each vibration impact. The mechanoreceptors innervated with the C-fibers are not excited by these frequencies. After a preliminary vibrostimulation the part of mechanoreceptors innervated with C-fibers do not respond to the mechanical stimulus tested. The higher the frequency of preliminary vibrostimulation, the fewer receptors respond to the tested stimulus.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 1","pages":"20-7"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12751952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Change in the background afferent influx to the spinal cord after transsecting the sciatic nerve and early enhancement of monosynaptic reflexes]. [坐骨神经横断后脊髓背景传入内流的变化和单突触反射的早期增强]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
E A Makiĭ, I Ia Serdiuchenko
{"title":"[Change in the background afferent influx to the spinal cord after transsecting the sciatic nerve and early enhancement of monosynaptic reflexes].","authors":"E A Makiĭ,&nbsp;I Ia Serdiuchenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Background impulse activity (BIA) of separate fibres of dorsal roots of 5 lumbar segment of rats after one-sided cutting of the sciatic nerve which caused early enhancement of monosynaptic segmental reflexes (5 days after operation) has been recorded. It is revealed that afferent fibres with BIA are found more rarely on side of cutting than on the opposite side and frequency of background activity is lower than in the opposite root. It is concluded that development of spontaneous activity of the spinal ganglion neurons after cutting nerves does not ensure a higher BIA level in afferent fibres. The given phenomenon cannot be a reason of early enhancement of monosynaptic reflexes after the nerve cutting.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 1","pages":"103-5"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12752101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the responsive ability of parietal associative cortex neurons to stimulation of associative thalamic nuclei during development of inhibition]. [抑制发育过程中顶叶联合皮层神经元对丘脑联合核刺激的反应能力变化]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
I V Timofeev, V D Taranenko
{"title":"[Changes in the responsive ability of parietal associative cortex neurons to stimulation of associative thalamic nuclei during development of inhibition].","authors":"I V Timofeev,&nbsp;V D Taranenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neuronal responses of area 7 of the parietal associative cortex (PAC) to paired stimulation of the nLD and nLP thalamic nuclei were investigated by extra- and intracellular recording methods. It was found out that testing stimulation of the associative nuclei resulted in inhibition, facilitation or absence of clear neuronal responses. Inhibition was observed more often then other types of reactions. The intracellular recording has shown that inhibition of responses to testing stimuli developed during the initial phase of IPSP, while in the repolarization phase a facilitation was possible. The reversion of a Cl- -dependent component of IPSP did not lead to inhibition of responses to the testing stimulation in that period. It is suggested that inhibition of responses to the testing stimulus occurs in the presence of inward Cl- -dependent current, while facilitation of responses may be a result of activation of the late EPSPs.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 2","pages":"198-207"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12765046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Organization of vestibulospinal systems in vertebrates]. [脊椎动物前庭脊髓系统的组织]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
L P Voĭtenko
{"title":"[Organization of vestibulospinal systems in vertebrates].","authors":"L P Voĭtenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The data about vestibular nuclear complex and vestibulospinal systems in the submammalian and mammalian vertebrates are offered in the review. Information presented in the world literature concerning the vestibular nuclei topography, structure, fibre connections and influences on the spinal cord and skeletal muscles is summarized. The current conceptions of the structural and functional specificity of different vestibulospinal systems are considered.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 2","pages":"215-38"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12765048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Extra-organ sources of parasympathetic innervation of small intestine in the region of ligament of Treitz]. [Treitz韧带区小肠副交感神经支配的器官外来源]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
V A Bagaev, L V Filippova, G N Akoev, F N Makarov
{"title":"[Extra-organ sources of parasympathetic innervation of small intestine in the region of ligament of Treitz].","authors":"V A Bagaev,&nbsp;L V Filippova,&nbsp;G N Akoev,&nbsp;F N Makarov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Localization sites of neurons in the dorsal motor nucleus of cat vagus innervating the duodenal-jejunal region and upper part of the jejunum were investigated using the technique of the retrograde axonal transport of horseradish peroxidase. Most part of the neurons was located within the ventrolateral area of the nucleus from +1.0 to +2.7 mm (according to obex). Morphological features of the ganglion nodosum neurons which organize afferent innervation of the intestine were analyzed. It has been shown that the maximal amount of such neurons is concentrated in the medium and caudal parts of the ganglion.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 4","pages":"423-30"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12606755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recruiting of motor units and changes of their firing rate as mechanisms of muscle contraction control]. [运动单元的招募及其放电速率的变化作为肌肉收缩控制的机制]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
R S Person
{"title":"[Recruiting of motor units and changes of their firing rate as mechanisms of muscle contraction control].","authors":"R S Person","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Main mechanisms of muscle contraction control: recruiting of motor units and changes of their firing rate are discussed in the review. Relative contribution of these mechanisms at different types of muscular activity (tonic contraction, vibration reflex, locomotion) is considered.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 4","pages":"501-5"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12606762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mechanism of vitamin B6 regulation of acetylcholine-induced currents in mollusk neurons: pre- and postsynaptic effects]. [维生素B6调节软体动物神经元乙酰胆碱诱导电流的机制:突触前和突触后效应]。
Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
V A Diatlov, E N Diatlova
{"title":"[Mechanism of vitamin B6 regulation of acetylcholine-induced currents in mollusk neurons: pre- and postsynaptic effects].","authors":"V A Diatlov,&nbsp;E N Diatlova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vitamin B6 has been studied for the mechanism of its effect on acetylcholine-induced sodium-potassium and chloride currents in E16 neuron of isolated brain of the snail Helix pomatia. The results indicate that the effect of vitamin B6 on acetylcholine-induced currents in postsynaptic neuron E16 is mediated via changes in gamma-aminobutyric acid (GABA) release from a presynaptic neuron and subsequent GABA-induced and cAMP-dependent processes in E16 neuron. It is suggested that effects of vitamin and antivitamin B6 on axons of a presynaptic neuron or neurons may be connected with regulation of GABA synthesis from glutamate catalyzed by the pyridoxal-phosphate-containing enzyme.</p>","PeriodicalId":19121,"journal":{"name":"Neirofiziologiia = Neurophysiology","volume":"24 4","pages":"411-22"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12504853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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