Nano Biomedicine最新文献_第9页

Evaluation of Adhesion between Material and Epithelium using a Three-dimensional Human Epidermal Model 利用三维人体表皮模型评估材料与上皮之间的粘附性

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.76

K. Furuhashi, T. Akasaka, Y. Kitagawa, F. Watari

{"title":"Evaluation of Adhesion between Material and Epithelium using a Three-dimensional Human Epidermal Model","authors":"K. Furuhashi, T. Akasaka, Y. Kitagawa, F. Watari","doi":"10.11344/NANO.4.76","DOIUrl":"https://doi.org/10.11344/NANO.4.76","url":null,"abstract":"76 Introduction Dental implants pass through the oral mucosa and bone, and protrude into the external environment of the oral cavity. In the case of natural teeth, junctional epithelium is adhered to the enamel via hemidesmosomes, and the periodontal inner tissue is protected from environmental insults. The dental implants that are currently used are problematic in that they do not adhere to the oral mucosa at the point of abutment, unlike natural teeth [1, 2]. Thus, there is an inherent risk that contaminants may pass through the interface between the implant and the mucosa and cause inflammation leading to bone resorption [3]. Therefore, it is important to develop a material that promotes contact with the tissue. For this purpose, animal experiments are usually necessary. However, animal experiments entail problems, such as ethical issues and species differences. It would be much easier if adhesion experiments could be done in vitro instead of in vivo. 3D tissue models cultured in vitro could be one of the candidates for this type of procedure. Tissue adhesion to the dental implant requires oral mucosal epithelium. However, an oral mucosal model has not been well established as yet. In this study, 3D tissue models derived from epidermal keratinocyte progenitor cells were used. Epithelium of the skin and oral mucosa were derived from the same ectoderm, and the nature of cutaneous epithelium was similar to that of oral epithelium. Adhesion Evaluation of Adhesion between Material and Epithelium using a Three-dimensional Human Epidermal Model","PeriodicalId":19070,"journal":{"name":"Nano Biomedicine","volume":"4 1","pages":"76-84"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11344/NANO.4.76","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63691023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Subcutaneous Tissue Reactions Against Nano-apatite Collagen Composites 纳米磷灰石胶原复合材料的皮下组织反应

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.118

Wataru Hatakeyama, M. Taira, Hidemichi Kihara, M. Sasaki, S. Kimura, H. Kondo

引用次数: 2

Assessment on a Biological Toxicity Caused by Single-walled Carbon Nanotubes 单壁碳纳米管的生物毒性评价

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.125

Takuma Tsuji, J. Usukura

引用次数: 1

Chemical Immobilization of Multi-walled Carbon Nanotubes onto Glass Surface in Aqueous Media 水介质中多壁碳纳米管在玻璃表面的化学固定

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.113

Tomoya Takada, Y. Konno, K. Nakayama, P. Dunuwila, Y. Maeda, S. Abe

引用次数: 0

In Situ Observation of Dynamic Response Behavior of Cells Exposed to Micro/nano Particles by Time Lapse Observation 微纳粒子作用下细胞动态响应行为的时间推移原位观察

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.59

Nobuki Iwadera, Y. Yawaka, F. Watari

引用次数: 0

Evaluation of Protein Adsorption to Carbon Nanotubes having Different Property, and Identification of Adsorbed Proteins 不同性质碳纳米管对蛋白质吸附的评价及吸附蛋白质的鉴定

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.66

M. Morikawa, Y. Kuboki, F. Watari

引用次数: 3

Guided Bone Regeneration: Membrane Characteristics and Future Perspectives 引导骨再生:膜特性和未来展望

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.42

Kanako Noritake, S. Kuroda, S. Kasugai

引用次数: 3

Effects of in Vitro Angiogenesis by Nano or Submicron Diamond Particles 纳米或亚微米金刚石颗粒对体外血管生成的影响

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.24

K. Imai, F. Watari

引用次数: 1

Synergic Toxicity of Solid Particles and Released Zinc from Zinc Oxide Nanoparticles to Human Lung Epithelial Cells 固体颗粒和氧化锌纳米颗粒释放的锌对人肺上皮细胞的协同毒性

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.90

Fei Zhuang, N. Hanagata

引用次数: 1

Evaluation of Bone Regeneration of Apatite Coating Poly-L-lactide Scaffold in Rat Calvarial Defects 磷灰石涂层聚l -丙交酯支架修复大鼠颅骨缺损的骨再生效果评价

Nano Biomedicine Pub Date : 2012-01-01 DOI: 10.11344/NANO.4.133

Kenichirou Yasui, Y. Hashimoto, S. Baba, S. Hontsu, N. Matsumoto

{"title":"Evaluation of Bone Regeneration of Apatite Coating Poly-L-lactide Scaffold in Rat Calvarial Defects","authors":"Kenichirou Yasui, Y. Hashimoto, S. Baba, S. Hontsu, N. Matsumoto","doi":"10.11344/NANO.4.133","DOIUrl":"https://doi.org/10.11344/NANO.4.133","url":null,"abstract":"133 Introduction Cleft lip and palate is a frequently occurring congenital malformation that is caused by genetic and environmental factors [1, 2]. Loss of alveolar bone due to the cleft can lead to problems with feeding and speech, among other difficulties; therefore, surgical closure is strongly recommended [3, 4]. Autogenous bone grafting for patients with cleft lip and palate has become a well-accepted treatment modality to restore the function and structure of the maxillary arch at the cleft site [5, 6]. However, the procedure is very invasive and the amount of collectable bone is limited. Allogeneic bone grafts may transmit diseases and can cause immune-related complications. It is therefore necessary to develop a synthetic alternative to current graft materials for bone regeneration [7]. In recent years, poly(L-lactide) (PLLA) has been widely evaluated as a scaffold biomaterial because of its impressive biocompatibility, biodegradability, minimal inflammatory reaction, and excellent mechanical properties [8]. However, PLLA is known to show poor cell–material interaction because of its hydrophobic nature and lack of cell recognition signals [9]. In order to promote cell adhesion, surface modification of PLLA is often attempted [9]. Evaluation of Bone Regeneration of Apatite Coating Poly-L-lactide Scaffold in Rat Calvarial Defects","PeriodicalId":19070,"journal":{"name":"Nano Biomedicine","volume":"1 1","pages":"133-142"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63690353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0