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Might Hydroxychloroquine Treat Primary Progressive Multiple Sclerosis 羟氯喹能治疗原发性进行性多发性硬化吗
NEJM Journal Watch Pub Date : 2021-10-25 DOI: 10.1056/NEJM-JW.NA54192
R. Naismith
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引用次数: 0
Bispecific Antibody Therapy for Relapsed Lymphoma 双特异性抗体治疗复发性淋巴瘤
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54216
Michael E. Williams
{"title":"Bispecific Antibody Therapy for Relapsed Lymphoma","authors":"Michael E. Williams","doi":"10.1056/NEJM-JW.NA54216","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54216","url":null,"abstract":"Bispecific therapeutic monoclonal antibodies are an emerging treatment option for acute lymphoblastic leukemia, non-Hodgkin lymphomas, and multiple","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79520870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Encephalitis and Acute Rituximab Treatment 自身免疫性脑炎和急性利妥昔单抗治疗
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54194
R. Naismith
{"title":"Autoimmune Encephalitis and Acute Rituximab Treatment","authors":"R. Naismith","doi":"10.1056/NEJM-JW.NA54194","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54194","url":null,"abstract":"Few randomized, controlled trials have been conducted to test treatments for the various forms of autoimmune encephalitis (AE). Investigators have now","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85341483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can a Long-Forgotten Antibiotic Be Repurposed Against Lyme Disease? 一种被遗忘已久的抗生素能否用于治疗莱姆病?
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54189
G. Sakoulas
{"title":"Can a Long-Forgotten Antibiotic Be Repurposed Against Lyme Disease?","authors":"G. Sakoulas","doi":"10.1056/NEJM-JW.NA54189","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54189","url":null,"abstract":"Lyme disease is increasing in the U.S. due to expansion of vector habitat, human encroachment in previously uninhabited areas, and longer seasonal","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88615985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recovery of Cognitive Functioning in Anti-NMDA Receptor Encephalitis 抗nmda受体脑炎患者认知功能的恢复
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54193
R. Naismith
{"title":"Recovery of Cognitive Functioning in Anti-NMDA Receptor Encephalitis","authors":"R. Naismith","doi":"10.1056/NEJM-JW.NA54193","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54193","url":null,"abstract":"Few studies describe the long-term cognitive dysfunction experienced by people with anti–N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. In","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81631327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Wheelchair Dependence in Facioscapulohumeral Muscular Dystrophy 预测面部肩胛肱肌萎缩症患者对轮椅的依赖
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54145
Leana Doherty
{"title":"Predicting Wheelchair Dependence in Facioscapulohumeral Muscular Dystrophy","authors":"Leana Doherty","doi":"10.1056/NEJM-JW.NA54145","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54145","url":null,"abstract":"Although facioscapulohumeral muscular dystrophy (FSHD) is one of the more common forms of muscular dystrophy, we know little about factors that predict","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86360158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial Therapy for 抗菌药物治疗
NEJM Journal Watch Pub Date : 2021-10-22 DOI: 10.1056/NEJM-JW.NA54162
G. Sakoulas
{"title":"Antimicrobial Therapy for","authors":"G. Sakoulas","doi":"10.1056/NEJM-JW.NA54162","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54162","url":null,"abstract":"Bloodstream infections with Pseudomonas aeruginosa often occur in highly comorbid, immunocompromised patients with previous antimicrobial exposure,","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81730888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myocarditis After BNT162b2 Vaccine Receipt in Israel 以色列BNT162b2疫苗接种后的心肌炎
NEJM Journal Watch Pub Date : 2021-10-21 DOI: 10.1056/NEJM-JW.NA54180
H. Krumholz, Sm
{"title":"Myocarditis After BNT162b2 Vaccine Receipt in Israel","authors":"H. Krumholz, Sm","doi":"10.1056/NEJM-JW.NA54180","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54180","url":null,"abstract":"Defining the frequency and severity of myocarditis after vaccination has great public health importance. Two retrospective Israeli studies have","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81390409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Edema as a Side Effect of Gabapentinoid Drugs 加巴喷丁类药物的副作用:水肿
NEJM Journal Watch Pub Date : 2021-10-21 DOI: 10.1056/NEJM-JW.NA54218
A. Brett
{"title":"Edema as a Side Effect of Gabapentinoid Drugs","authors":"A. Brett","doi":"10.1056/NEJM-JW.NA54218","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54218","url":null,"abstract":"Edema is a well-described side effect of gabapentinoid drugs (i.e., gabapentin and pregabalin). In this study from Ontario, Canada, researchers used","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87951447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antihypertensive Augmentation: Maximize Dose or Add a New Med? 降压增强:最大剂量还是增加一种新药物?
NEJM Journal Watch Pub Date : 2021-10-21 DOI: 10.1056/NEJM-JW.NA54147
D. Dressler, Mhm, Facp.
{"title":"Antihypertensive Augmentation: Maximize Dose or Add a New Med?","authors":"D. Dressler, Mhm, Facp.","doi":"10.1056/NEJM-JW.NA54147","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54147","url":null,"abstract":"In drug-treated patients with hypertension whose blood pressure (BP) is inadequately controlled, augmentation strategies include maximizing the dose of","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79591825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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