{"title":"Another Monoclonal Therapy Option for Early COVID-19","authors":"R. Ellison","doi":"10.1056/NEJM-JW.NA54243","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54243","url":null,"abstract":"One of the most heartening advances in the management of COVID-19 is the development of monoclonal antibody preparations that effectively lower risk","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74209493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PCI vs. CABG for Left Main Coronary Artery Disease","authors":"D. Cohen","doi":"10.1056/NEJM-JW.NA54313","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54313","url":null,"abstract":"Patients with significant left main coronary artery disease (LMCAD) traditionally have been treated with coronary artery bypass graft surgery (CABG) —","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82930987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Longer-Term Follow-Up in Patients Receiving AAV Gene Therapy for Hemophilia A","authors":"B. Stein, Mhs","doi":"10.1056/NEJM-JW.NA54280","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54280","url":null,"abstract":"Major aims in the treatment of hemophilia A include reducing bleeding events, avoiding severe arthropathy, and improving quality of life. Among the","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80394856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Further Evidence to Support a Low-Sodium, High-Potassium Diet","authors":"A. Brett","doi":"10.1056/NEJM-JW.NA54291","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54291","url":null,"abstract":"Studies with various limitations generally have shown that high sodium intake and low potassium intake are associated with higher risk for hypertension","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75431977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influenza Vaccination in Children: Recommendations for the 2021–2022 Season","authors":"D. Lehman","doi":"10.1056/NEJM-JW.NA54091","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54091","url":null,"abstract":"Sponsoring Organization: American Academy of Pediatrics (AAP)BackgroundThe AAP annually reviews its recommendations for routine influenza immunization;","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82671428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should Steroid Dosing in COPD Exacerbations Be Individualized","authors":"N. Winawer, Sfhm","doi":"10.1056/NEJM-JW.NA54315","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54315","url":null,"abstract":"Evidence suggests that shorter courses of systemic corticosteroids are preferable for patients hospitalized with acute exacerbations of chronic","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76043617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuropathy with Neurofascin-155 Immunoglobulins: Clinical Profile and Prognosis","authors":"Leana Doherty","doi":"10.1056/NEJM-JW.NA54230","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54230","url":null,"abstract":"Little is known about long-term outcomes in patients with neuropathy and neurofascin-155 immunoglobulin G4 (NF155-IgG4) antibodies, and even less about","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81960796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Surviving Sepsis Guidelines","authors":"P. Kritek","doi":"10.1056/NEJM-JW.NA54288","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54288","url":null,"abstract":"Sponsoring Organizations: Society of Critical Care Medicine (SCCM); European Society of Intensive Care Medicine (ESICM)BackgroundThis is the fourth","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83697662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Comatose Survivors of Out-of-Hospital-Cardiac Arrest, Colder Isn't Better","authors":"A. Calderon, Facp., Sfhm","doi":"10.1056/NEJM-JW.NA54209","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54209","url":null,"abstract":"Current guidelines recommend targeted temperature management between 32°C and 36°C for a minimum of 24 hours in all comatose patients with return of","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73476431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FOLFIRINOX Not Better Than Gemcitabine-Cisplatin in Biliary Cancer","authors":"D. Ilson","doi":"10.1056/NEJM-JW.NA54286","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54286","url":null,"abstract":"Standard chemotherapy agents for advanced biliary cancer are gemcitabine and cisplatin. Recent data suggest a modest benefit for use of second-line","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89041944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}