{"title":"Medication Harms Leading to Emergency Department Visits","authors":"D. Dressler, Mhm, Facp.","doi":"10.1056/NEJM-JW.NA54263","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54263","url":null,"abstract":"Harms related to medications occur commonly. However, the frequency of emergency department (ED) visits and types of medications that lead to harm have","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91520158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Aspirin Use Before Stroke Improve Functional Outcome","authors":"S. Chaturvedi","doi":"10.1056/NEJM-JW.NA54249","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54249","url":null,"abstract":"Despite changing recommendations, aspirin is widely used for both primary and secondary prevention of vascular events such as myocardial infarction and","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82039849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Clinical Care Pathway” for Nonalcoholic Fatty Liver Disease","authors":"A. Brett","doi":"10.1056/NEJM-JW.NA54262","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54262","url":null,"abstract":"Sponsoring Organization: American Gastroenterological Association (AGA)BackgroundBecause the prevalence of nonalcoholic fatty liver disease (NAFLD) is","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87184449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liposome Encapsulated Irinotecan Is Active in Cholangiocarcinoma","authors":"D. Ilson","doi":"10.1056/NEJM-JW.NA54260","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54260","url":null,"abstract":"Standard first-line chemotherapy for advanced cholangiocarcinoma is gemcitabine and cisplatin. Recent data support the use of FOLFOX as a second-line","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87259878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccination-Associated Injection-Site Infections Before the COVID-19 Era","authors":"S. Baum","doi":"10.1056/NEJM-JW.NA54228","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54228","url":null,"abstract":"Vaccination has become a highly charged issue during the COVID-19 pandemic — but previously, millions of U.S. children and adults received","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74738312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment Failure in Patients with Moderately Severe Community-Acquired Pneumonia","authors":"A. Parsons","doi":"10.1056/NEJM-JW.NA54212","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54212","url":null,"abstract":"Previously identified risk factors for treatment failure for community-acquired pneumonia (CAP) included advanced age, smoking, malnutrition, and","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89080005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anakinra: Timely Targeted Anticytokine Therapy for Severe COVID-19","authors":"N. Ampel","doi":"10.1056/NEJM-JW.NA54236","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54236","url":null,"abstract":"Identifying patients at excess risk for severe COVID-19 is critical for devising treatment strategies (particularly those involving immune modulation)","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87119403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is Complete Rest Really the Best Treatment for Sports-Related Concussions?","authors":"J. Feinstein","doi":"10.1056/NEJM-JW.NA54190","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54190","url":null,"abstract":"Clinicians who care for adolescents with sports-related concussions typically recommend strict cognitive and physical rest, but some recent evidence","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87833456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial Superinfection Is Found in a Minority of Patients Admitted with COVID-19 Respiratory Failure","authors":"P. Kritek","doi":"10.1056/NEJM-JW.NA54261","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54261","url":null,"abstract":"When patients with COVID-19 are admitted to the intensive care unit, guidelines recommend empirical coverage for bacterial superinfection with","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90665898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Second Doses of COVID-19 mRNA Vaccines Are Important in Pregnancy","authors":"A. Komaroff","doi":"10.1056/NEJM-JW.NA54254","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54254","url":null,"abstract":"The immune system of a pregnant woman maintains a delicate balance: It must tolerate the “foreign” antigens of the fetus while still protecting the","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86240148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}