Mycopathologia最新文献_第10页

Onychomycosis of Hand and Foot due to Acremonium egyptiacum. 埃及癣菌（Acremonium egyptiacum）引起的手足癣菌病。

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00823-0

Rodrigo Cruz Choappa, Peggy Vieille Oyarzo, Melisa Noguera Gahona, Massimo Cogliati

引用次数: 0

Tinea Capitis Combined with Tinea Vellus in a 4-year-old Boy. 一名 4 岁男童的头癣合并黄癣。

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00816-z

Jiahao Li, Wenying Cai, Li Lin, Guiquan Lu, Xinzhe Xie, Sha Lu

引用次数: 0

Trends in the Incidence of Disseminated Cryptococcosis in Japan: A Nationwide Observational Study, 2015-2021. 日本播散性隐球菌病的发病趋势：2015-2021 年全国观察研究》。

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00814-1

Hidemasa Akazawa, Hideharu Hagiya, Toshihiro Koyama, Fumio Otsuka

{"title":"Trends in the Incidence of Disseminated Cryptococcosis in Japan: A Nationwide Observational Study, 2015-2021.","authors":"Hidemasa Akazawa, Hideharu Hagiya, Toshihiro Koyama, Fumio Otsuka","doi":"10.1007/s11046-023-00814-1","DOIUrl":"10.1007/s11046-023-00814-1","url":null,"abstract":"Background: Cryptococcus species can cause severe disseminated infections in immunocompromised hosts. This study investigated the epidemiological features and trends in disseminated cryptococcosis in Japan.Methods: We used publicly available Infectious Diseases Weekly Reports to obtain data on the incidence of disseminated cryptococcosis in Japan from 2015 to 2021. Patient information, including age, sex, and regional and seasonal data, were extracted. The Joinpoint regression program was used to determine the age-adjusted incidence rate (AAR) per 100,000 population, annual percentage change (APC), and average APC (AAPC).Results: A total of 1047 cases of disseminated cryptococcosis were reported, of which those aged ≥ 70 years accounted for 68.8%. The AAR in men was significantly higher than that in women (median: 0.13 vs. 0.09: p = 0.0024). APC for the overall cases increased by 9.9% (95% confidence interval [95% CI] - 5.4-27.7) from 2015 to 2018 and then decreased by 3.3% (95% CI - 15.5-10.7) from 2018 to 2021. AAPC for the entire study period was 3.1% (95% CI - 1.5-8.0), indicating a possible increase in its number, although not statistically significant. In terms of regional distribution, the average AAR was highest in Shikoku District (0.17) and lowest in Hokkaido District (0.04). Northern Japan exhibited a significantly lower median AAR (median [interquartile range]: 0.06 [0.05, 0.08]) than the Eastern (0.12 [0.12, 0.13]), Western (0.11 [0.10, 0.13]), and Southern (0.14 [0.12, 0.15]) regions. No seasonal variation in incidence was observed.Conclusion: The prevalence of disseminated cryptococcosis has not increased in Japan. Geographically, the incidence is lower in Northern Japan. Further investigations that incorporate detailed clinical data are required.","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":"189 1","pages":"8"},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176. 伊曲康唑减敏马杜氏菌 CBS 129176 型菌株的完整基因组序列。

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00807-0

Mickey Konings, Bert Gerrits van den Ende, Mirthe W J Raats, Ahmed Hassan Fahal, Wendy W J van de Sande, Ferry Hagen

引用次数: 0

Mixed Aspergillosis and Mucormycosis Infections in Patients with COVID-19: Case Series and Literature Review. COVID-19 患者的曲霉菌病和粘孢子菌病混合感染：病例系列和文献综述

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00808-z

Elahe Sasani, Farzad Pakdel, Sadegh Khodavaisy, Mohammadreza Salehi, Amir Salami, Marjan Sohrabi, Pouyan Aminishakiba, Iman Amirafzali, Arezoo Salami Khaneshan

{"title":"Mixed Aspergillosis and Mucormycosis Infections in Patients with COVID-19: Case Series and Literature Review.","authors":"Elahe Sasani, Farzad Pakdel, Sadegh Khodavaisy, Mohammadreza Salehi, Amir Salami, Marjan Sohrabi, Pouyan Aminishakiba, Iman Amirafzali, Arezoo Salami Khaneshan","doi":"10.1007/s11046-023-00808-z","DOIUrl":"10.1007/s11046-023-00808-z","url":null,"abstract":"Background: Mucormycosis and aspergillosis are angioinvasive infections mainly occurring in immunocompromised patients. However, mixed infection with mucormycosis and aspergillosis in post-COVID-19 patients is rare. In this report, we will report four cases and comprehensively review the published literature on COVID-19 associated mixed infection of aspergillosis and mucormycosis.Method: Besides four of our cases, we searched for published articles using PubMed/MEDLINE, Scopus, and Web of Science databases from the beginning of 2020 until October 2023.Result: During the COVID-19 pandemic, we analyzed 52 cases (4 from our research and 48 from other studies). The most common underlying disease (59.6%) was diabetes mellitus. However, 19.2% of COVID-19 patients had no underlying condition. Interestingly, rhino-orbital-cerebral mucormycosis featured prominently in India and Iran, while other countries primarily reported a higher prevalence of pulmonary cases.Conclusion: In conclusion, this study highlights the presence of mixed aspergillosis and mucormycosis in COVID-19 patients who previously had common underlying diseases or even a healthy immune system. Therefore, managing COVID-19 patients should involve screening serum and respiratory samples using biomarkers to detect superinfections.","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":"189 1","pages":"10"},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subcutaneous Hyalohyphomycosis Caused by Scedosporium aurantiacum Treated with Posacanazole. 使用泊沙康唑治疗由枳壳壳孢子菌引起的皮下霉菌病

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00824-z

Kayo Kashiwada-Nakamura, Hiromitsu Noguchi, Takashi Yaguchi, Kazumi Urata, Shuichi Shimada, Soichiro Sawamura, Katsunari Makino, Ikko Kajihara, Katsumasa Ideo, Sara Higuchi, Satoshi Fukushima

引用次数: 0

Disseminated Basidiobolomycosis Caused by Basidiobolus omanensis in a Child with Acute Lymphoblastic Leukemia (ALL). Case Report and Literature Review. 一名急性淋巴细胞白血病（ALL）患儿因阿曼巴斯迪波洛斯菌引起的播散性巴斯迪波洛斯菌病。病例报告与文献综述。

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00820-3

Laila Al Yazidi, Sharifa Al Sinani, Badriya Al Adawi, Marwa Al Riyami, Yasser Wali, Abdulhakeem Al Rawas, Buthaina Al Musalhi, Jacques F Meis, Saif Al Housni, Ahmed Al-Harrasi, Abdullah M S Al Hatmi

{"title":"Disseminated Basidiobolomycosis Caused by Basidiobolus omanensis in a Child with Acute Lymphoblastic Leukemia (ALL). Case Report and Literature Review.","authors":"Laila Al Yazidi, Sharifa Al Sinani, Badriya Al Adawi, Marwa Al Riyami, Yasser Wali, Abdulhakeem Al Rawas, Buthaina Al Musalhi, Jacques F Meis, Saif Al Housni, Ahmed Al-Harrasi, Abdullah M S Al Hatmi","doi":"10.1007/s11046-023-00820-3","DOIUrl":"10.1007/s11046-023-00820-3","url":null,"abstract":"Basidiobolomycosis is an uncommon fungal infection caused by the genus Basidiobolus. In immunocompetent children, it usually causes cutaneous infection and rarely affects the gastrointestinal tract, and it is extremely rare for the disease to spread. The present study reports the first case of disseminated basidiobolomycosis caused by Basidiobolus omanensis in a child with acute lymphoblastic leukemia who died as a result of uncontrolled infection and multi-organ failure despite surgical and antifungal therapy with L-AMB and voriconazole. A review of the literature yielded 76 cases, including the current case with the majority of which were reported as invasive gastrointestinal infection. The median age was 4 years (61 male and 15 female) and the majority of these children were from the Middle East (80%), specifically Saudi Arabia (45%). Most patients were treated with systemic antifungal agents (mostly itraconazole and amphotericin B). Surgical intervention was done in 25% of these patients and the death rate was 12%.","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":"189 1","pages":"12"},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishment of a Novel Short Tandem Repeat Typing Method for Exophiala dermatitidis. 建立皮炎嗜血杆菌的新型短串联重复分型方法

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00825-y

Hamide Zoqi, Dirk Schmidt, Ludwig Sedlacek, Peter-Michael Rath, Joerg Steinmann, Lisa Kirchhoff

{"title":"Establishment of a Novel Short Tandem Repeat Typing Method for Exophiala dermatitidis.","authors":"Hamide Zoqi, Dirk Schmidt, Ludwig Sedlacek, Peter-Michael Rath, Joerg Steinmann, Lisa Kirchhoff","doi":"10.1007/s11046-023-00825-y","DOIUrl":"10.1007/s11046-023-00825-y","url":null,"abstract":"The opportunistic black yeast-like fungus Exophiala dermatitidis frequently colonizes the respiratory tract of cystic fibroses (CF) patients. Additionally, it can cause superficial, systemic, and cerebral forms of phaeohyphomycoses. The objective of this study was to develop and apply a microsatellite or short tandem repeat (STR) genotyping scheme for E. dermatitidis. In total, 82 E. dermatitidis isolates from various geographic origins (environmental = 9, CF = 63, invasive isolates = 9, melanin-deficient mutant = 1) were included in this study. After next-generation sequencing of a reference strain and sequence filtering for microsatellites, six STR markers were selected and amplified in two multiplex PCR reactions. The included isolates were discriminated in a genetic cluster analysis using the Pearson algorithm to reveal the relatedness of the isolates. The E. dermatitidis isolates clustered on basis of both, their source and their origin. The invasive isolates from Asia were unrelated to isolates from CF. Nearly all environmental isolates were grouped separately from patients' isolates. The Simpson index was 0.94. In conclusion, we were able to establish a STR genotyping scheme for investigating population genomics of E. dermatitidis.","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":"189 1","pages":"5"},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Observation of a Bone Invasion Model of Aspergillus fumigatus In Vitro and Analysis of the Antifungal Susceptibility. 体外曲霉菌骨侵袭模型观察及抗真菌敏感性分析

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00817-y

Yan Shao, Min Shen, Dan Peng, Wenxu Cheng, Chenggang Mao, Heng Zhang, Yi Sun

{"title":"Observation of a Bone Invasion Model of Aspergillus fumigatus In Vitro and Analysis of the Antifungal Susceptibility.","authors":"Yan Shao, Min Shen, Dan Peng, Wenxu Cheng, Chenggang Mao, Heng Zhang, Yi Sun","doi":"10.1007/s11046-023-00817-y","DOIUrl":"10.1007/s11046-023-00817-y","url":null,"abstract":"Background: Recently, the prevalence of invasive fungal infections has been on the rise, and one of the prevalent symptoms frequently observed is bone deterioration and bone loss.Materials and methods: Using an in vitro model we studied how Aspergillus fumigatus invades the bone. Pathological analysis was then employed to observe the structure and distinctive features of the invading fungal elements within the bone invasion model. Meanwhile, the antifungal effects of itraconazole, voriconazole, posaconazole, and amphotericin B were evaluated.Results: The pathological findings showed that in the experimental group, fungal spores and hyphae invaded the bone tissue or were observed growing in the vicinity of the bone edge tissues, as indicated by both HE and PAS staining. In contrast, no fungal elements were observed in the control group, indicating that the in vitro bone invasion model of A. fumigatus was successfully constructed. Furthermore, the findings from the antifungal sensitivity test demonstrated that the lowest effective concentrations of antifungal drugs against the bone invasion model were as follows: 4 μg/ml for itraconazole, 0.5 μg/ml for voriconazole, 2 μg/ml for posaconazole, and 2 μg/ml for amphotericin B.Discussion: The successful construction of the bone invasion model of A. fumigatus has provided a solid basis for future investigations into the mechanisms underlying A. fumigatus bone invasion and the study of its virulence factors. Utilizing bone models is of utmost importance in advancing the development of novel antifungal treatment approaches, as well as in effectively preventing and treating fungal bone invasion and osteolytic diseases.","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":"189 1","pages":"4"},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 associated Pulmonary Aspergillosis in Patients Admitted to the Intensive Care Unit: Impact of Antifungal Prophylaxis 入住重症监护室患者中与 COVID-19 相关的肺曲霉菌病：抗真菌预防措施的影响

IF 5.5 3区生物学

Mycopathologia Pub Date : 2024-01-13 DOI: 10.1007/s11046-023-00809-y

Jonas Frost, Maximilian Gornicec, A. Reisinger, Philipp Eller, Martin Hoenigl, J. Prattes

引用次数: 0