发布求助
文献互助 智能选刊 最新文献

Mycopathologia最新文献

筛选
英文 中文
Establishment of a Novel Short Tandem Repeat Typing Method for Exophiala dermatitidis. 建立皮炎嗜血杆菌的新型短串联重复分型方法
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00825-y
Hamide Zoqi, Dirk Schmidt, Ludwig Sedlacek, Peter-Michael Rath, Joerg Steinmann, Lisa Kirchhoff
{"title":"Establishment of a Novel Short Tandem Repeat Typing Method for Exophiala dermatitidis.","authors":"Hamide Zoqi, Dirk Schmidt, Ludwig Sedlacek, Peter-Michael Rath, Joerg Steinmann, Lisa Kirchhoff","doi":"10.1007/s11046-023-00825-y","DOIUrl":"10.1007/s11046-023-00825-y","url":null,"abstract":"<p><p>The opportunistic black yeast-like fungus Exophiala dermatitidis frequently colonizes the respiratory tract of cystic fibroses (CF) patients. Additionally, it can cause superficial, systemic, and cerebral forms of phaeohyphomycoses. The objective of this study was to develop and apply a microsatellite or short tandem repeat (STR) genotyping scheme for E. dermatitidis. In total, 82 E. dermatitidis isolates from various geographic origins (environmental = 9, CF = 63, invasive isolates = 9, melanin-deficient mutant = 1) were included in this study. After next-generation sequencing of a reference strain and sequence filtering for microsatellites, six STR markers were selected and amplified in two multiplex PCR reactions. The included isolates were discriminated in a genetic cluster analysis using the Pearson algorithm to reveal the relatedness of the isolates. The E. dermatitidis isolates clustered on basis of both, their source and their origin. The invasive isolates from Asia were unrelated to isolates from CF. Nearly all environmental isolates were grouped separately from patients' isolates. The Simpson index was 0.94. In conclusion, we were able to establish a STR genotyping scheme for investigating population genomics of E. dermatitidis.</p>","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Observation of a Bone Invasion Model of Aspergillus fumigatus In Vitro and Analysis of the Antifungal Susceptibility. 体外曲霉菌骨侵袭模型观察及抗真菌敏感性分析
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2024-01-17 DOI: 10.1007/s11046-023-00817-y
Yan Shao, Min Shen, Dan Peng, Wenxu Cheng, Chenggang Mao, Heng Zhang, Yi Sun
{"title":"Observation of a Bone Invasion Model of Aspergillus fumigatus In Vitro and Analysis of the Antifungal Susceptibility.","authors":"Yan Shao, Min Shen, Dan Peng, Wenxu Cheng, Chenggang Mao, Heng Zhang, Yi Sun","doi":"10.1007/s11046-023-00817-y","DOIUrl":"10.1007/s11046-023-00817-y","url":null,"abstract":"<p><strong>Background: </strong>Recently, the prevalence of invasive fungal infections has been on the rise, and one of the prevalent symptoms frequently observed is bone deterioration and bone loss.</p><p><strong>Materials and methods: </strong>Using an in vitro model we studied how Aspergillus fumigatus invades the bone. Pathological analysis was then employed to observe the structure and distinctive features of the invading fungal elements within the bone invasion model. Meanwhile, the antifungal effects of itraconazole, voriconazole, posaconazole, and amphotericin B were evaluated.</p><p><strong>Results: </strong>The pathological findings showed that in the experimental group, fungal spores and hyphae invaded the bone tissue or were observed growing in the vicinity of the bone edge tissues, as indicated by both HE and PAS staining. In contrast, no fungal elements were observed in the control group, indicating that the in vitro bone invasion model of A. fumigatus was successfully constructed. Furthermore, the findings from the antifungal sensitivity test demonstrated that the lowest effective concentrations of antifungal drugs against the bone invasion model were as follows: 4 μg/ml for itraconazole, 0.5 μg/ml for voriconazole, 2 μg/ml for posaconazole, and 2 μg/ml for amphotericin B.</p><p><strong>Discussion: </strong>The successful construction of the bone invasion model of A. fumigatus has provided a solid basis for future investigations into the mechanisms underlying A. fumigatus bone invasion and the study of its virulence factors. Utilizing bone models is of utmost importance in advancing the development of novel antifungal treatment approaches, as well as in effectively preventing and treating fungal bone invasion and osteolytic diseases.</p>","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 associated Pulmonary Aspergillosis in Patients Admitted to the Intensive Care Unit: Impact of Antifungal Prophylaxis 入住重症监护室患者中与 COVID-19 相关的肺曲霉菌病：抗真菌预防措施的影响
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2024-01-13 DOI: 10.1007/s11046-023-00809-y
Jonas Frost, Maximilian Gornicec, A. Reisinger, Philipp Eller, Martin Hoenigl, J. Prattes
{"title":"COVID-19 associated Pulmonary Aspergillosis in Patients Admitted to the Intensive Care Unit: Impact of Antifungal Prophylaxis","authors":"Jonas Frost, Maximilian Gornicec, A. Reisinger, Philipp Eller, Martin Hoenigl, J. Prattes","doi":"10.1007/s11046-023-00809-y","DOIUrl":"https://doi.org/10.1007/s11046-023-00809-y","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139437241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Loop-Mediated Isothermal Amplification for the Detection of Prototheca bovis Directly from Milk Samples of Dairy Cattle 开发环路介导等温扩增技术，直接从奶牛牛奶样本中检测牛原虫
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2024-01-13 DOI: 10.1007/s11046-023-00806-1
S. M. Rivelli Zea, Megumi Itoh, Takahito Toyotome
{"title":"Development of Loop-Mediated Isothermal Amplification for the Detection of Prototheca bovis Directly from Milk Samples of Dairy Cattle","authors":"S. M. Rivelli Zea, Megumi Itoh, Takahito Toyotome","doi":"10.1007/s11046-023-00806-1","DOIUrl":"https://doi.org/10.1007/s11046-023-00806-1","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139437146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Verification of Trichophyton in the Brazilian URM Culture Collection 巴西 URM 培养物中毛癣菌的分子验证
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2024-01-13 DOI: 10.1007/s11046-023-00811-4
Tatiana F. Oliveira, C. A. Valeriano, M. D. S. Buonafina-Paz, C. M. Souza-Motta, A. R. Machado, Rejane P. Neves, J. D. Bezerra, T. D. Arantes, S. Hoog, O. Magalhães
{"title":"Molecular Verification of Trichophyton in the Brazilian URM Culture Collection","authors":"Tatiana F. Oliveira, C. A. Valeriano, M. D. S. Buonafina-Paz, C. M. Souza-Motta, A. R. Machado, Rejane P. Neves, J. D. Bezerra, T. D. Arantes, S. Hoog, O. Magalhães","doi":"10.1007/s11046-023-00811-4","DOIUrl":"https://doi.org/10.1007/s11046-023-00811-4","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139437470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstracts from 11th Trends in Medical Mycology 第 11 届医学真菌学趋势会议摘要
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2023-12-07 DOI: 10.1007/s11046-023-00805-2
{"title":"Abstracts from 11th Trends in Medical Mycology","authors":"","doi":"10.1007/s11046-023-00805-2","DOIUrl":"https://doi.org/10.1007/s11046-023-00805-2","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138554386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Mist Under Woods Lamp: fungal infection covered by eyedrops. 木灯下的雾:眼药水覆盖的真菌感染。
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2023-12-01 Epub Date: 2023-09-05 DOI: 10.1007/s11046-023-00789-z
Xiaoyu Sun, Yangyang Ma, Wenting Hu
{"title":"A Mist Under Woods Lamp: fungal infection covered by eyedrops.","authors":"Xiaoyu Sun, Yangyang Ma, Wenting Hu","doi":"10.1007/s11046-023-00789-z","DOIUrl":"10.1007/s11046-023-00789-z","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10527272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Amplification PCR (LA-PCR) Detection of Azole Resistant Trichophyton indotineae. 长扩增聚合酶链式反应（LA-PCR）检测耐偶氮毛癣菌。
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2023-12-01 Epub Date: 2023-09-26 DOI: 10.1007/s11046-023-00793-3
Tsuyoshi Yamada, Honoka Nojo, Rui Kano
{"title":"Long Amplification PCR (LA-PCR) Detection of Azole Resistant Trichophyton indotineae.","authors":"Tsuyoshi Yamada, Honoka Nojo, Rui Kano","doi":"10.1007/s11046-023-00793-3","DOIUrl":"10.1007/s11046-023-00793-3","url":null,"abstract":"<p><p>Trichphyton indotineae, a species newly designated in 2020 independent of T. interdigitale, comprises highly terbinafine (TRF)-resistant dermatophytosis that is epidemic in North India and spreding to worldwide. Some clinical isolates of T. indotineae have been resistance both TRF and azoles that might be caused the treatment failure. To detect the azole resistance strains, we developed a long amplification PCR (LA-PCR) detection method for the tandem repeat of the CYP51B (encoding sterol 14a-demethylase gene) in T. indotineae. Contrasting the drug susceptibility test results with the LA-PCR results confirmed a trend toward low susceptibility to azole antifungal agents in strains with amplifications of 9.5 kbp or greater (3 or more copies of CYP51B). Our results suggest that the method could be detected rapidly of low-susceptibility strains to azole antifungal agents.</p>","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41141481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: The Domestic Isolation of Terbinafine- and Itraconazole Resistant Trichophyton indotineae in Chinese Mainland. 更正：中国大陆国内分离到的耐特比萘芬和伊曲康唑的印度毛癣菌。
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2023-12-01 DOI: 10.1007/s11046-023-00804-3
Xue Kong, Ge Song, Huan Mei, Hailin Zheng, Chao Tang, Sybren de Hoog, Xiaofang Li, Xiaodong She, Weida Liu, Guanzhao Liang
{"title":"Correction to: The Domestic Isolation of Terbinafine- and Itraconazole Resistant Trichophyton indotineae in Chinese Mainland.","authors":"Xue Kong, Ge Song, Huan Mei, Hailin Zheng, Chao Tang, Sybren de Hoog, Xiaofang Li, Xiaodong She, Weida Liu, Guanzhao Liang","doi":"10.1007/s11046-023-00804-3","DOIUrl":"10.1007/s11046-023-00804-3","url":null,"abstract":"","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71425240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Candida Infectious Endocarditis and Implantable Cardiac Device Infections. 念珠菌感染性心内膜炎和植入式心脏装置感染。
IF 5.5 3区 生物学
Mycopathologia Pub Date : 2023-12-01 Epub Date: 2023-06-05 DOI: 10.1007/s11046-023-00745-x
Risa Fuller, Samantha E Jacobs
{"title":"Candida Infectious Endocarditis and Implantable Cardiac Device Infections.","authors":"Risa Fuller, Samantha E Jacobs","doi":"10.1007/s11046-023-00745-x","DOIUrl":"10.1007/s11046-023-00745-x","url":null,"abstract":"<p><p>Intravascular diseases due to Candida species, including endocarditis and cardiac device-associated infections, are rare yet devastating manifestations of invasive candidiasis affecting an already vulnerable population. Despite their significant associated morbidity and mortality, limited prospective data exist to inform the optimal diagnostic and therapeutic approaches to these entities. Herein, we review the existing literature pertaining to the epidemiology, diagnosis, and management of infectious endocarditis, rhythm management device infections, and circulatory support device infections caused by Candida species and suggest areas for future research.</p>","PeriodicalId":19017,"journal":{"name":"Mycopathologia","volume":null,"pages":null},"PeriodicalIF":5.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9577469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信