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Specifics of the Taxonomic Composition of Bacterial Microflora in the Respiratory Microbiome of Patients with Chronic Dust Bronchitis 慢性粉尘支气管炎患者呼吸道微生物群中细菌微生物群的分类组成特点
4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-06-01 DOI: 10.3103/s0891416823020076
S. A. Paradnikova, V. G. Druzhinin, E. D. Baranova, P. S. Demenkov, A.V. Larionov
{"title":"Specifics of the Taxonomic Composition of Bacterial Microflora in the Respiratory Microbiome of Patients with Chronic Dust Bronchitis","authors":"S. A. Paradnikova, V. G. Druzhinin, E. D. Baranova, P. S. Demenkov, A.V. Larionov","doi":"10.3103/s0891416823020076","DOIUrl":"https://doi.org/10.3103/s0891416823020076","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Genetic Variants of the Cholera Agent and Their Distribution in Endemic Countries and Russia 霍乱病原体的新基因变异及其在流行国家和俄罗斯的分布
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010093
N. Smirnova, D. A. Rybal’chenko, N. A. Plekhanov, Yu. V. Lozovsky, A. Fedorov, V. Kutyrev
{"title":"New Genetic Variants of the Cholera Agent and Their Distribution in Endemic Countries and Russia","authors":"N. Smirnova, D. A. Rybal’chenko, N. A. Plekhanov, Yu. V. Lozovsky, A. Fedorov, V. Kutyrev","doi":"10.3103/S0891416823010093","DOIUrl":"https://doi.org/10.3103/S0891416823010093","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"18 1","pages":"8-15"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82971734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The First Detection of Ebinur Lake Virus (Orthobunyavirus, Peribunyaviridae) in Russia 俄罗斯首次发现艾比纳湖病毒(原布尼亚病毒，环布尼亚病毒科)
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010020
E. Avdiusheva, D. N. Luchinin, N. Borodai, A. Antonov, D. Ustinov, E. Molchanova, I. Shpak, D. Viktorov, A. Toporkov
{"title":"The First Detection of Ebinur Lake Virus (Orthobunyavirus, Peribunyaviridae) in Russia","authors":"E. Avdiusheva, D. N. Luchinin, N. Borodai, A. Antonov, D. Ustinov, E. Molchanova, I. Shpak, D. Viktorov, A. Toporkov","doi":"10.3103/S0891416823010020","DOIUrl":"https://doi.org/10.3103/S0891416823010020","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"90 1","pages":"41-46"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89785170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determining the Antibacterial Effect of Recombinant CpsA-CpsC-L-ACAN Fusion Peptide against E. coli and Staphylococcus aureus 重组CpsA-CpsC-L-ACAN融合肽对大肠杆菌和金黄色葡萄球菌抑菌效果的研究
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010032
Elmira Babakanrad, T. Mohammadian, D. Esmaeili, P. Behzadi
{"title":"Determining the Antibacterial Effect of Recombinant CpsA-CpsC-L-ACAN Fusion Peptide against E. coli and Staphylococcus aureus","authors":"Elmira Babakanrad, T. Mohammadian, D. Esmaeili, P. Behzadi","doi":"10.3103/S0891416823010032","DOIUrl":"https://doi.org/10.3103/S0891416823010032","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"23 1","pages":"47-52"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73715870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Haplotype AH8.1 Normalizes the Level of Tumor Necrosis Factor in the Blood Sera of Breast-Cancer Patients 自身免疫单倍型AH8.1使乳腺癌患者血清肿瘤坏死因子水平正常化
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S089141682301007X
T. Malivanova, T. Astrelina, I. Kobzeva, V. Nikitina, Y. Suchkova, A. S. Ostashkin, D. Usupzhanova, E. I. Dobrovolskaya, V. Brunchukov, A. Rastorgueva, E. E. Lomonosova, E. Lubaeva, E. Y. Kretova, N. G. Stepanyants, M. Sukhova, A. Samoilov
{"title":"Autoimmune Haplotype AH8.1 Normalizes the Level of Tumor Necrosis Factor in the Blood Sera of Breast-Cancer Patients","authors":"T. Malivanova, T. Astrelina, I. Kobzeva, V. Nikitina, Y. Suchkova, A. S. Ostashkin, D. Usupzhanova, E. I. Dobrovolskaya, V. Brunchukov, A. Rastorgueva, E. E. Lomonosova, E. Lubaeva, E. Y. Kretova, N. G. Stepanyants, M. Sukhova, A. Samoilov","doi":"10.3103/S089141682301007X","DOIUrl":"https://doi.org/10.3103/S089141682301007X","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"133 1","pages":"34-40"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86252990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proteomic Analysis in Microbiology 微生物学中的蛋白质组学分析
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010081
T. Sharov, D. Viktorov, A. Toporkov
{"title":"Proteomic Analysis in Microbiology","authors":"T. Sharov, D. Viktorov, A. Toporkov","doi":"10.3103/S0891416823010081","DOIUrl":"https://doi.org/10.3103/S0891416823010081","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"23 1","pages":"1-7"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86349779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Pseudomonas syringae pv. phaseolicola NPS3121 the Regulator HrpL is Required for Siderophore Biosynthesis 在丁香假单胞菌pv。调控因子HrpL是铁载体生物合成所必需的
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010044
Lizeth Guardado-Valdivia, Alejandra Chacón-López, José Luis Hernández-Flores, L. Xoca-Orozco, E. Montalvo-González, Selene Aguilera
{"title":"In Pseudomonas syringae pv. phaseolicola NPS3121 the Regulator HrpL is Required for Siderophore Biosynthesis","authors":"Lizeth Guardado-Valdivia, Alejandra Chacón-López, José Luis Hernández-Flores, L. Xoca-Orozco, E. Montalvo-González, Selene Aguilera","doi":"10.3103/S0891416823010044","DOIUrl":"https://doi.org/10.3103/S0891416823010044","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"3 1","pages":"53-60"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81547533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of MYBPC3 Gene Mutations in Russian Patients with Hypertrophic Cardiomyopathy 俄罗斯肥厚性心肌病患者MYBPC3基因突变的患病率
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S0891416823010068
A. L. Klass, N. Krylova, A. Lysenko, I. Vlasov, M. Maslova, G. I. Salagaev, E. Kovalevskaya, N. Poteshkina, M. Shadrina, P. Slominsky, E. V. Filatova
{"title":"Prevalence of MYBPC3 Gene Mutations in Russian Patients with Hypertrophic Cardiomyopathy","authors":"A. L. Klass, N. Krylova, A. Lysenko, I. Vlasov, M. Maslova, G. I. Salagaev, E. Kovalevskaya, N. Poteshkina, M. Shadrina, P. Slominsky, E. V. Filatova","doi":"10.3103/S0891416823010068","DOIUrl":"https://doi.org/10.3103/S0891416823010068","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"7 1","pages":"16-20"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78948407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nitrosonium Cation NO^+ Inhibits Nitric-Oxide Functions in the Regulation of Pseudomonas aeruginosa Biofilm Formation 亚硝基离子NO^+抑制一氧化氮在铜绿假单胞菌生物膜形成中的作用
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2023-03-01 DOI: 10.3103/S089141682301010X
S. Vasilieva, N. V. Alekseeva, Y. Romanova, A. F. Vanin
{"title":"Nitrosonium Cation NO^+ Inhibits Nitric-Oxide Functions in the Regulation of Pseudomonas aeruginosa Biofilm Formation","authors":"S. Vasilieva, N. V. Alekseeva, Y. Romanova, A. F. Vanin","doi":"10.3103/S089141682301010X","DOIUrl":"https://doi.org/10.3103/S089141682301010X","url":null,"abstract":"","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"50 1","pages":"29-33"},"PeriodicalIF":0.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87580858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Efficiency of Bacteriophage Lytic Enzymes in the Course of Bacterial Ghost Generation 噬菌体裂解酶在细菌幽灵生成过程中的效率
IF 0.5 4区 生物学
Molecular Genetics, Microbiology and Virology Pub Date : 2022-12-25 DOI: 10.3103/s0891416822030077
M. E. Platonov, A. S. Vagaiskaya, A. S. Trunyakova, D. V. Grinenko, V. N. Gerasimov, S. V. Dentovskaya, A. P. Anisimov
{"title":"The Efficiency of Bacteriophage Lytic Enzymes in the Course of Bacterial Ghost Generation","authors":"M. E. Platonov, A. S. Vagaiskaya, A. S. Trunyakova, D. V. Grinenko, V. N. Gerasimov, S. V. Dentovskaya, A. P. Anisimov","doi":"10.3103/s0891416822030077","DOIUrl":"https://doi.org/10.3103/s0891416822030077","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Bacterial ghosts (BGs) are gram-negative bacteria cell membranes without cytoplasmic content obtained by lysis as a result of cell-wall perforation mediated by the φX174 bacteriophage E protein. Introducing into a lytic plasmid lysis gene from other bacteriophages, which target alternative molecular targets, in addition to the E protein gene of bacteriophage φX174, can lead to an increase in the efficiency of lysis and, in some cases, to an increase in the immunogenicity of preparations. <i>Escherichia coli</i> strains carrying plasmids with various combinations of genes encoding protein E of phage φ174 with cassettes of lytic genes of the “choline–endolysin” systems of phages λ or L-413C, providing different degrees of destruction of the cell wall, were obtained for the subsequent selection of the most promising lytic structures. The formation of <i>E. coli</i> ghosts and the release of cell contents was confirmed by transmission electron microscopy. When the cultivation temperature was increased from 28 to 42°C, the lysis of <i>E. coli</i> cultures DH5α/pEYR'-E, DH5α/pEYR'-Y-K, DH5α/pEYR'-E-Y-K, and DH5α/pEYR'-E-Sam7-R-Rz was observed. Lysis was practically not detected during the growth of the DH5α/pEYR'-S-R-Rz culture, as in the control strain DH5α/pEYR'. The results of the analysis of ultrathin sections of BGs preparations by transmission electron microscopy (TEM) were comparable with the data on optical density and the results of inoculation of induced cultures of engineered strains, and also made it possible to assess the fine structure of bacterial cells carrying various combinations of lytic phage genes. BGs of gram-negative bacteria are promising for the creation of highly effective inactivated candidate vaccines that could replace currently available bacterial heat-inactivated and formol vaccines.</p>","PeriodicalId":19005,"journal":{"name":"Molecular Genetics, Microbiology and Virology","volume":"76 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138542320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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