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Shining a light on structural genomics. 点亮结构基因组学的光芒。
Nature Structural Biology Pub Date : 1998-08-01 DOI: 10.1038/1334
S H Kim
{"title":"Shining a light on structural genomics.","authors":"S H Kim","doi":"10.1038/1334","DOIUrl":"https://doi.org/10.1038/1334","url":null,"abstract":"","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"643-5"},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/1334","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20615881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 108
Bright prospects for biological non-crystalline diffraction. 生物非晶衍射的光明前景。
Nature Structural Biology Pub Date : 1998-08-01 DOI: 10.1038/1340
T C Irving
{"title":"Bright prospects for biological non-crystalline diffraction.","authors":"T C Irving","doi":"10.1038/1340","DOIUrl":"https://doi.org/10.1038/1340","url":null,"abstract":"","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"648-50"},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/1340","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20615883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Protein dynamics from NMR. 来自NMR的蛋白质动力学。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/755
L E Kay
{"title":"Protein dynamics from NMR.","authors":"L E Kay","doi":"10.1038/755","DOIUrl":"https://doi.org/10.1038/755","url":null,"abstract":"<p><p>In the past several years a significant number of new multidimensional NMR methods have been developed to study molecular dynamics spanning a wide range of time scales. Applications involving a large number of biological systems have emerged and correlations with function established. Unique insights are obtained that are not available from structure alone, indicating the importance of dynamics studies for understanding function.</p>","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"513-7"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/755","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 174
Dipolar recoupling in MAS spectra of biological solids. 生物固体的MAS光谱中的偶极重耦合。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/749
R G Griffin
{"title":"Dipolar recoupling in MAS spectra of biological solids.","authors":"R G Griffin","doi":"10.1038/749","DOIUrl":"https://doi.org/10.1038/749","url":null,"abstract":"<p><p>In combination with magic angle spinning, dipolar recoupling yields solid state NMR spectral assignments and provides constraints on internuclear distances and torsion angles. The method offers a fresh approach to structural studies of a variety of systems that cannot be examined with conventional tools available to structural biology.</p>","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"508-12"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/749","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 287
New techniques in structural NMR--anisotropic interactions. 结构核磁共振的新技术——各向异性相互作用。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/756
J H Prestegard
{"title":"New techniques in structural NMR--anisotropic interactions.","authors":"J H Prestegard","doi":"10.1038/756","DOIUrl":"https://doi.org/10.1038/756","url":null,"abstract":"<p><p>Structure determination of biomolecules by NMR has traditionally been based on nuclear Overhauser effects (NOEs). Now there are additional sources of information that can complement NOEs in cases where positioning of remote parts of molecules is important, and where extension to larger and more complex systems is desired.</p>","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"517-22"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/756","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 156
Kinetic studies of protein folding using NMR spectroscopy. 用核磁共振光谱研究蛋白质折叠的动力学。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/744
C M Dobson, P J Hore
{"title":"Kinetic studies of protein folding using NMR spectroscopy.","authors":"C M Dobson,&nbsp;P J Hore","doi":"10.1038/744","DOIUrl":"https://doi.org/10.1038/744","url":null,"abstract":"","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"504-7"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/744","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 78
The second decade--into the third millenium. 第二个十年，进入第三个千年。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/728
K Wüthrich
{"title":"The second decade--into the third millenium.","authors":"K Wüthrich","doi":"10.1038/728","DOIUrl":"https://doi.org/10.1038/728","url":null,"abstract":"<p><p>NMR spectroscopy is one of the principal experimental techniques of structural biology, with abilities to determine atomic resolution structures as well as investigate dynamics and intermolecular interactions of biological macromolecules. There is plenty of room for continued progress of this young branch of science, based on further technical advances as well as innovative funding strategies and project organization.</p>","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"492-5"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/728","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 125
Equilibrium NMR studies of unfolded and partially folded proteins. 未折叠和部分折叠蛋白质的平衡核磁共振研究。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/739
H J Dyson, P E Wright
{"title":"Equilibrium NMR studies of unfolded and partially folded proteins.","authors":"H J Dyson,&nbsp;P E Wright","doi":"10.1038/739","DOIUrl":"https://doi.org/10.1038/739","url":null,"abstract":"","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"499-503"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 189
NMR of modular proteins. 模块蛋白的核磁共振。
Nature Structural Biology Pub Date : 1998-07-01 DOI: 10.1038/733
I D Campbell, A K Downing
{"title":"NMR of modular proteins.","authors":"I D Campbell,&nbsp;A K Downing","doi":"10.1038/733","DOIUrl":"https://doi.org/10.1038/733","url":null,"abstract":"<p><p>NMR studies of domains, dissected from large modular proteins, are described. Particular emphasis is placed on modules from the extracellular proteins fibrillin-1 and fibronectin.</p>","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 Suppl ","pages":"496-9"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/733","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20582532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 35
Picture story. Channels, channels everywhere. 图片故事。渠道，渠道无处不在。
Nature Structural Biology Pub Date : 1998-06-01
{"title":"Picture story. Channels, channels everywhere.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18848,"journal":{"name":"Nature Structural Biology","volume":"5 6","pages":"420"},"PeriodicalIF":0.0,"publicationDate":"1998-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20547664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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