Florian Bretin, M. Bahri, G. Warnock, A. Luxen, A. Seret, A. Plenevaux
{"title":"X-ray dose quantification for various scanning protocols with the GE eXplore 120 micro-CT","authors":"Florian Bretin, M. Bahri, G. Warnock, A. Luxen, A. Seret, A. Plenevaux","doi":"10.1109/NSSMIC.2012.6551866","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551866","url":null,"abstract":"The aim of this study was to quantify the dose delivered by several standard protocols on a GE eXplore 120 micro-CT (Gamma Medica I GE Healthcare) using the computed tomography dose index over 100 mm (CTDI100). Four different protocols with tube voltages of 70 kVp and 80 kVp were investigated by measuring the spatial dose distribution over 100 mm in the axial direction for 9 transaxial positions inside a custom-built cylindrical PMMA phantom. All dose measurements were performed using a mobileMOSFET Dose Verification System (Best Medical Canada, Canada). The axial dose profile of the transaxial center position was used for the CTDl100 calculation. The Fast scan (70 kVp, 0.512 mAs, 192°) delivered a mean dose of 13.92 ± 0.10 mGy, the Fast scan 360 (70 kVp, 0.512 mAs, 360°) 21.24 ± 0.26 mGy, the Soft Tissue Fast scan (70 kVp, 1.6 mAs, 192°) 38.37 ± 0.97 mGy and the Soft Tissue (80 kVp, 0.512 mAs, 192°, step & shoot) 19.63 ± 0.17 mGy. In order to compare the X-ray tube dose output per mAs the CTDI100 of the protocols with 192° were normalized to 360° gantry rotation. At 70 kVp tube voltage the dose output was 45.81 ± 3.92 mGy/mAs across all protocols and 71.89 mGy/mAs at 80 kVp. Protocols with 192° gantry rotation showed inhomogeneity of the dose distribution in the transaxial direction.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"222 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115529218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Chichester, S. Thompson, S. Watson, James T. Johnson, E. Seabury
{"title":"Estimation of the performance of multiple active neutron interrogation signatures for detecting shielded HEU","authors":"D. Chichester, S. Thompson, S. Watson, James T. Johnson, E. Seabury","doi":"10.1109/NSSMIC.2012.6551199","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551199","url":null,"abstract":"A comprehensive modeling study has been carried out to evaluate the utility of multiple active neutron interrogation signatures for detecting shielded highly enriched uranium (HEU). The modeling effort focused on varying HEU masses from 1 kg to 20 kg; varying types of shields including cement, wood, polyethylene, aluminum, and steel; varying depths of the HEU in the shields, and varying engineered shields immediately surrounding the HEU including steel, lead, and cadmium. Neutron and gamma-ray signatures were the focus of the study and false negative detection probabilities versus measurement time were used as a performance metric. To facilitate comparisons among different approaches an automated method was developed to generate receiver operating characteristic (ROC) curves for different sets of model variables for multiple background count rate conditions. This paper summarizes results or the analysis, including laboratory benchmark comparisons between simulations and experiments.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116074309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Streun, H. Noldgen, G. Kemmerling, S. van Waasen
{"title":"Position reconstruction in monolithic block detectors","authors":"M. Streun, H. Noldgen, G. Kemmerling, S. van Waasen","doi":"10.1109/NSSMIC.2012.6551733","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551733","url":null,"abstract":"In high resolution PET systems the detector generally uses a scintillator which consists of individual pixel elements. The scintillation light of such a pixel element will be identified and thus the interaction is localized by the pixel position. Consequently, the delivered position of such a detector can only take discrete values. A different approach is the monolithic scintillator detector. A continuous scintillator block spans over an area of several photodetector pixels and the position is reconstructed from the recorded light distribution. Manufacturing of this detector is easier and the sensitivity is generally higher as no scintillating material is wasted for optical isolation between the pixels. But the challenge is to find a dedicated algorithm in order to identify the interaction position with sufficient resolution. We will present measurements of a monolithic scintillator detector (21×18×10mm3 LYSO) and compare different reconstruction methods. Already a Least Square Optimization algorithm based on a rather simple model delivers a resolution similar to an Artificial Neural Network approach but which requires pre-registered data for training. The comparison of the resolution to that of a pixelated detector of similar size and 2×2×10mm3 pixels shows the superior performance of the continuous block.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116518679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of discrete versus continuous prior image in sparse-view CT","authors":"Sajid Abbas, Seungryong Cho","doi":"10.1109/NSSMIC.2012.6551557","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551557","url":null,"abstract":"Sparse-view CT is a viable option for low-dose CT, and much efforts have been made to develop image reconstruction algorithms for sparse-view CT. Iterative image reconstruction algorithms are choices of reconstruction which discretize a continuous imaging model by voxelizing the image and by approximating the x-ray transform based on the voxels. Prior image has been utilized to further reduce the number of views in sparse-view CT, but the utilization of such a prior image in discrete domain may result in a suboptimal image quality due to the approximation. In this paper, we present a comparison study on the effects of using projections from a continuous prior image versus a discrete prior image. We implemented a total-variation (TV) minimization algorithm that can reconstruct the image from sparse-view data using prior image knowledge. It is shown that higher-quality images can be obtained by use of the projections of a continuous prior image in the sparse-view CT.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116526726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal experimentation for nuclear medicine imaging system design","authors":"Didar Talat, S. Beylergil, A. Guvenis","doi":"10.1109/NSSMIC.2012.6551615","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551615","url":null,"abstract":"We investigated the potential applications of the response surface methodology (RSM) for nuclear medicine imaging systems optimization. RSM is a technique used to improve system or process design in a wide range of applications in engineering. RSM is essentially a technique and body of knowledge that helps find the set of design parameters that will achieve the best system performance by conducting a minimal number of experiments. It also helps us determine the effect of parameters and their interactions on the system. While traditional approaches to experimentation consider the effect of each parameter separately, RSM relies on the simultaneous optimization with respect to all parameters. This technique is particularly suitable for nuclear medicine imaging systems since the cost of real or simulated experiments is very high and therefore a systematic and efficient experimentation with a simultaneous parameter optimization scheme is essential. RSM can also be used for multiple objective optimization problems where more than one system performance variable is optimized. In this paper, we first present the foundations of RSM and its applications in various fields. We then give an example from a breast scintigraphy collimator optimization problem to illustrate the use of RSM in nuclear medicine imaging systems optimization.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122599535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rebinning of conical projection data in compton imaging","authors":"Mi No Lee, Soojin Lee","doi":"10.1109/NSSMIC.2012.6551540","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551540","url":null,"abstract":"This paper presents a rebinning method for the reconstruction from Compton scattered conical projection data. Our rebinning method converts the 3-D conical projection data set into a stack of 2-D parallel projection data set so that a variety of existing 2-D analytical reconstruction methods developed for conventional emission tomography can be directly used for Compton imaging. In our rebinning method, the following three steps are performed. (i) A cone surface is sampled with a serial of lines that pass through the apex of the cone. (ii) By using the rotating imaginary planes, which are perpendicular to the transaxial (x-y) plane and parallel to the z axis, the sampled projection lines, which are mostly perpendicular to the imaginary planes, are sorted at each rotation angle. (iii) The sorted lines, most of which are oblique in the transaxial plane, are approximated to equivalent 2-D parallel projections in the transaxial plane using the Fourier rebinning (FORE) technique. Since our method is very fast, it can be useful for rapidly reconstructing Compton scattered data using fast analytical reconstruction methods.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122981457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparisons motion correction methods for PET studies","authors":"I. Hong, Z. Burbar, C. Michel","doi":"10.1109/NSSMIC.2012.6551750","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551750","url":null,"abstract":"Motion in PET studies degrades the image quality and introduces bias which is critical for high resolution scanners such as mCT, mMR, and HRRT. There are many publications related to motion correction in PET. They consider either Rigid-body or Non Rigid-body motion and use three methods for motion correction. In this work we will describe and compare three motion correction methods. The first method performs motion correction in image space, while the second method performs motion correction in sinogram (or LOR) space and then reconstruct the motion corrected sinogram. The third method performs motion correction during the reconstruction process. Amongst the three methods, one should be selected depending on the amount of motion, the selected isotope, and the application: brain, cardiac, or whole body. In this work, three rigid body motion correction methods are compared for brain application.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114253491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Baesso, D. Cussans, Paul Glaysher, C. Thomay, J. Velthuis, Caroline Vassallo
{"title":"Muon scattering tomography with resistive plate chambers","authors":"P. Baesso, D. Cussans, Paul Glaysher, C. Thomay, J. Velthuis, Caroline Vassallo","doi":"10.1109/NSSMIC.2012.6551060","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551060","url":null,"abstract":"Muon Scattering Tomography is a scanning technique which uses cosmic muons as probes to gather information on the content of the inspected volume. Because the scattering angle depends on the Z2 of the materials in the volume, it is possible to obtain a 3D image of the volume content by carefully tracking the muon paths. This has very interesting potential applications in several fields, from engineering to homeland security, where MST could be used to inspect shipping containers and trucks in search of special nuclear materials (SNM). For such applications to be feasible it is necessary to have large area detectors (10-100 square meters) while maintaining the efficiency and angular resolution necessary to discriminate between low-Z and high-Z materials. Resistive Plate Chambers (RPCs) are very good candidates. RPCs are widely adopted in high energy physics experiments thanks to their excellent performance in terms of time resolution, charged particle detection efficiency and low cost per unit area. In collaboration with the UK Atomic Weapon Establishment we have built and tested a prototype based on 12 RPCs (50 cm × 50 cm). To obtain the required spatial resolution we adopted a novel approach for the RPC readout, coupling each detector with 300 fine pitch strips (1.5 mm) and using multiplexing analog readout chips to reduce the amount of readout channels. The prototype performs very well: all the chambers have efficiency above 99% and purity above 95%. The signal-to-noise for the electronic readout ranges from 25 to 90. The spatial resolution for the layers is better than 1 mm and we show that this is sufficient to successfully image a block of lead of 10 cm × 10 cm × 15 cm. We are now in the process of upgrading the electronics with new ASICs which feature built-in ADCs. The first test","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114262716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Blasco, E. Sanchis, D. Granero, V. González, J. D. Martin, D. Barrientos, F. J. Egea
{"title":"Simulation study and validation of the read-out electronics design for a high-resolution Plastic Scintillating Fiber based hodoscope for beam positioning","authors":"J. Blasco, E. Sanchis, D. Granero, V. González, J. D. Martin, D. Barrientos, F. J. Egea","doi":"10.1109/NSSMIC.2012.6551208","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551208","url":null,"abstract":"This work presents a study of a high-resolution Plastic Scintillating Fiber (PSF) based hodoscope for beam positioning and beam calibration. The aim of this work is to provide useful information to carry out a sound comparison between the results obtained from the electronics read-out designed for the hodoscope versus the results obtained from Geant4 simulations of the PSF detector; therefore, to validate the correct functioning of the device with the proposed read-out electronics design. To carry out this task, the physical properties of the hodoscope and its geometry have been described in the simulations as close as possible to the real detection system, as well as the real test conditions. Hence, we present, on the one hand, simulations in which β particles impinge the device: these simulations will be validated by comparing them with real measurements obtained when irradiating the PSF hodoscope with a Sr-90 (33 MBq) source. On the other hand, we present simulation results of the modeled detector when a proton source with different energies is placed over the device: in this case, simulations results will prove the feasibility of the proposed detector in applications such as hadrontherapy.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122018207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of undoped CeF3 scintillators at room and liquid nitrogen temperature","authors":"W. Klamra, P. Sibczyński, M. Moszynski, V. Kozlov","doi":"10.1109/NSSMIC.2012.6551115","DOIUrl":"https://doi.org/10.1109/NSSMIC.2012.6551115","url":null,"abstract":"In this paper properties of various undoped CeF3 scintillators were investigated at room and liquid nitrogen (LN2) temperature. The study was focused on measurements of radioluminescence spectra, decay time, non-proportional response on X- and γ-rays and energy resolution at different temperature environment. Surprisingly, the pure CeF3 crystals show comparable non-proportionality curves, which are very similar to that presented by inorganic scintillators. The investigation of the phenomenon occurring in CeF3 scintillators would be another step to get a better knowledge of the scintillators nature, which still haven't been entirely understood.","PeriodicalId":187728,"journal":{"name":"2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116618012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}