Minerva ginecologica最新文献

{"title":"Could art cycles have a detrimental effect on ovarian reserve? A retrospective case control study.","authors":"Lucia Riganelli,&nbsp;Lucia Merlino,&nbsp;Cesare Aragona,&nbsp;Oriana Capri,&nbsp;Silvia Franceschetti,&nbsp;Antonella Linari,&nbsp;Marianna Mariani,&nbsp;Giulietta Micara,&nbsp;Daniela Pietrangeli,&nbsp;Maria G Porpora,&nbsp;Maria G Piccioni","doi":"10.23736/S0026-4784.20.04542-6","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04542-6","url":null,"abstract":"<p><strong>Background: </strong>Even if it is supposed damage of repeated ART (assisted reproductive technology) cycles on oocyte pool, there is still no evidence in literature. Aim of the study is to investigate whether infertile women who undergo to several ART cycles can show a lower ovarian reserve measured by AMH (Anti-Mullerian hormone) levels.</p><p><strong>Methods: </strong>The study includes 282 infertile women, between 18 and 42 years, and allocated into two groups: 159 women previously submitted to two or more ART cycles (group A) and 123 women never submitted naïve to-ART cycles (group B). We tested whether AMH, FSH, LH and E2 levels were significantly different between the two groups, stratifying according to age.</p><p><strong>Results: </strong>Regardless to the age ranges bands, the AMH in group A was statistically significant lower than in group B with a statistical significance (P=0.047). In particular women aged over 35 previously submitted to one or more ART cycles showed lower AMH levels, than those paired with age, which had never been treated with ART.</p><p><strong>Conclusions: </strong>Despite the limitations of the study, our data demonstrate a reduced AMH levels in women aged over 35 previously submitted to two or more repeated ART-cycles compared to patients never treated before. The strength of this study is the actuality of the topic that has not been discussed before in detail.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 2","pages":"75-81"},"PeriodicalIF":1.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37931347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience in the use of synthetic prosthetic material in genital prolapse surgery.","authors":"Anuar I Korkan,&nbsp;Assem S Aketayeva,&nbsp;Assiya K Turgambayeva,&nbsp;Dulat M Imashpayev,&nbsp;Kulzhami Ospanova,&nbsp;Aliya Alimbayeva","doi":"10.23736/S0026-4784.20.04507-4","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04507-4","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 2","pages":"119-120"},"PeriodicalIF":1.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37931350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Gestational diabetes].","authors":"G. Ferraris, P. Gaido, A. Russo, L. Corbetta","doi":"10.31525/ct1-nct04270578","DOIUrl":"https://doi.org/10.31525/ct1-nct04270578","url":null,"abstract":"During pregnancy the body goes through a change in its metabolism that affects the way sugar is processed. In early pregnancy, blood sugar is more easily absorbed by the cells in the body. This prevents that too much glucose reaches the baby, which could be dangerous for its development. Around the middle of the pregnancy, the blood sugar will tend to be less absorbed by the cells, which means there is more sugar in the blood available for the baby to grow – this process is called “glucose intolerance”. If there is too much sugar circulating in the blood this can become a problem for the baby. When the woman has GD her body may have more difficulty regulating its blood sugar by itself which can lead to “hyperglycemia” (elevated blood sugar).","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"31 5 1","pages":"337-45"},"PeriodicalIF":1.0,"publicationDate":"2020-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48180221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Congenital toxoplasmosis].","authors":"P. Ritossa","doi":"10.32388/8y4w8s","DOIUrl":"https://doi.org/10.32388/8y4w8s","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"17 15 1","pages":"738-44"},"PeriodicalIF":1.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47060223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paget Disease of the Vulva","authors":"","doi":"10.32388/9eoloa","DOIUrl":"https://doi.org/10.32388/9eoloa","url":null,"abstract":"An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei. Qeios · Definition, February 7, 2020","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69627136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of primary Sjogren's syndrome on female sexual function.","authors":"Maria G Piccioni,&nbsp;Lucia Merlino,&nbsp;Marianna Deroma,&nbsp;Federica Del Prete,&nbsp;Sara Tabacco,&nbsp;Marco Monti,&nbsp;Pierluigi Benedetti Panici","doi":"10.23736/S0026-4784.20.04494-9","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04494-9","url":null,"abstract":"<p><strong>Introduction: </strong>Sjogren syndrome (SS) is a chronic autoimmune disease that usually affects women more than man with a 9:1 ratio. It leads to a progressive functional impairment of exocrine glands. Tipically, its clinical presentation is characterized by xerostomia and xerophtalmia, but it can also affect, among others, female genital apparatus, causing vaginal dryness and dyspareunia.</p><p><strong>Evidence acquisition: </strong>PubMed and Google Scholar were searched for articles in English indexed from January 1995 to November 2019 to assess evidence on the impact of primary Sjogren's syndrome on female sexual function. Our attention was directed specifically on the quality of sexual life of patients affected by primary SS.</p><p><strong>Evidence synthesis: </strong>SS is associated with sexual dysfunction and it can significantly worsen patient's quality of life.</p><p><strong>Conclusions: </strong>The genital disorders secondary to SS can strongly alter the quality of female life both physically and psychologically as they alter sexuality. However, the observation of certain behavioral norms and the use of appropriate local substances can alleviate the symptoms and effectively contribute to reducing the discomfort.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 1","pages":"50-54"},"PeriodicalIF":1.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37720675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An open trial of a visnadine emulgel topical application in post-menopausal superficial dyspareunia: daily vs. on-demand use.","authors":"A. Caputo, Adele Sparavigna, A. Natoli, C. Mandelli","doi":"10.23736/S0026-4784.19.04402-2","DOIUrl":"https://doi.org/10.23736/S0026-4784.19.04402-2","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47978768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV genotype distribution and age correlation in a selected Italian population undergoing conization.","authors":"Francesca Malentacchi,&nbsp;Cecilia Bussani,&nbsp;Dora Pavone,&nbsp;Karin L Anderson,&nbsp;Massimiliano Fambrini,&nbsp;Chiara Cocco,&nbsp;Giulia Fantappiè,&nbsp;Annalisa Pieralli,&nbsp;Valeria Dubini,&nbsp;Felice Petraglia,&nbsp;Flavia Sorbi","doi":"10.23736/S0026-4784.20.04506-2","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04506-2","url":null,"abstract":"BACKGROUND\u0000Detection and genotyping of human papillomavirus (HPV) has gained increasing importance in cervical cancer prevention and treatment of cervical intraepithelial neoplasia (CIN). This study aims to determine the HPV type distribution in cervical specimens obtained from women diagnosed with CIN. We evaluated in a selected Italian population the distribution of HPV genotypes.\u0000\u0000\u0000METHODS\u0000Cervical samples were collected from women undergoing laser CO2 conization for high grade at Colposcopic Laser Surgery Unit of the Careggi University Hospital and at the Colposcopy Service of Local Health Unit Toscana Centro in Florence, Italy, between September 2014 and February 2017. HPV genotyping was performed using the LINEAR ARRAY® HPV Genotyping Test.\u0000\u0000\u0000RESULTS\u0000Three hundred and six patients were enrolled. HPV infection was detected on 244 samples (79.7%). A different rate of mono- and poly-infections was observed, with higher poly-infection rates in younger women. Moreover, depending on different age groups (clustered in 5-years interval from 22 to 69 years old) significant different distribution of HPV was fund as genotype, phylogenetic type and cancer-related risk.\u0000\u0000\u0000CONCLUSIONS\u0000Our results suggest that some physiological conditions (i.e. menopause), could influence selection and clearance of specific HPV genotypes. The results of this study represent the basis for supporting the HPV genotyping as clinical tool providing benefits in the management of women with high CIN grade.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 1","pages":"1-11"},"PeriodicalIF":1.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37722244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive outcome after operative hysteroscopy for uterine septum: scissors or diathermy?","authors":"Angelos Daniilidis,&nbsp;Antonis Kalpatsanidis,&nbsp;Uzeyir Kalkan,&nbsp;Stamatis Kasmas,&nbsp;George Pados,&nbsp;Stefano Angioni","doi":"10.23736/S0026-4784.20.04444-5","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04444-5","url":null,"abstract":"<p><strong>Introduction: </strong>Hysteroscopic septoplasty is a safe and routinely used procedure for the treatment of septate uterus. The aim of this paper is to determine which hysteroscopic technique (scissors, monopolar/bipolar diathermy) is superior for post-treatment reproductive outcome.</p><p><strong>Evidence acquisition: </strong>Two different hysteroscopic septoplasty instruments (scissors and monopolar/bipolar diathermy) were compared, focusing on the pregnancy outcome. In addition, all published studies and reviews regarding pregnancy outcomes that occurred after operative hysteroscopy using different techniques (bipolar, monopolar electrodes, resectoscope, VERSAPOINT™ [Ethicon LLC] and scissors) were reviewed. Dichotomous analysis, with use of the Mantel-Haenszel method, was performed for all five outcomes, with fixed effect analysis model and odds ratio (OR) as the effect measure. Analysis details included totals and subtotals with 95% confidence interval. The Multinomial CI package for the R statistical language was also used.</p><p><strong>Evidence synthesis: </strong>Out of 26 full-text articles available in the literature, two studies were finally selected as eligible, with a total number of 125 patients. Pregnancy rate for scissors was 88.8% and for resectoscope was 75.6% (OR: 2.13, I2=29%; P=0.23). Delivery rate for scissors was 78.1% and for resectoscope was 75.0% (OR: 1.29, I2=0%; P=0.53). Miscarriage rate for scissors was 21.8% and for resectoscope was 27.1% (OR: 0.78, I2=0%; P=0.53). Preterm delivery rate for scissors was 6.2% and for resectoscope was 6.7% (OR: 0.85, I2=0%; P=0.94). Term delivery rate for scissors was 71.8% and for resectoscope was 66.1% (OR: 1.32, I2=0%; P=0.47). The lack of evidence in literature regarding the potential influence in the reproductive outcome of the instrument used when performing a hysteroscopy to treat a septate uterus became radically clear.</p><p><strong>Conclusions: </strong>No statistically significant differences were observed in reproductive outcomes between women treated for septate uterus using resectoscope or scissors.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 1","pages":"36-42"},"PeriodicalIF":1.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37722249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-year follow-up in patients with urinary stress incontinence treated with Altis® single-incision sling.","authors":"Gloria D'alessandro,&nbsp;Maurizio Leone,&nbsp;Jacopo Antolini,&nbsp;Simone Ferrero,&nbsp;Paolo Sala,&nbsp;Guglielmo Melloni,&nbsp;Giuseppe Fasolis,&nbsp;Claudio Gustavino","doi":"10.23736/S0026-4784.20.04496-2","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04496-2","url":null,"abstract":"<p><strong>Background: </strong>The purpose of the study is to report three years follow-up of single incision slings for the treatment of stress urinary incontinence (SUI). The main outcomes are to evaluate the efficacy of the device and to assess safety, adverse events, quality of life, demographic features of treated women and prognostic factors for SUI.</p><p><strong>Methods: </strong>We performed a retrospective, double-center, single-arm study. Data were collected by medical records and a telephone interview 3 years after the implant of the mini-sling. Complication rate, subjective efficacy and degree of satisfaction were investigated.</p><p><strong>Results: </strong>Fifty-four patients were treated between March 2015 and March 2017, of which 47 answered the survey. Forty-one of 47 procedures (87.2%) were considered effective. Among more relevant complications, there was one case of extrusion of mesh and three cases of new onset of urinary disfunction, of which two cases of urgency urinary incontinence (UUI) and one case of de-novo SUI. Most complications were solved within few days after the procedure. Concerning the subjective impression of improvement, investigated by using the Patient Global Impression of Improvement (PGI-I) questionnaires, 41 patients reported subjective satisfaction, three reported no change in quality of life and three patients had worsening of symptoms.</p><p><strong>Conclusions: </strong>The procedure was safe and effective for the treatment of SUI but more data are needed to confirm our preliminary results.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 1","pages":"12-18"},"PeriodicalIF":1.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37722245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}