Modern Rheumatology Case Reports最新文献_第7页

A review of rheumatoid meningitis with case studies. 类风湿性脑膜炎病例研究综述。

Modern Rheumatology Case Reports Pub Date : 2023-06-19 DOI: 10.1093/mrcr/rxad010

Merve Aktan Suzgun, Nursena Erener, Gokce Hande Cavus, Ayse Ozdede, Sabriye Guner, Serdal Ugurlu, Nil Comunoglu, Osman Kizilkilic, Sabahattin Saip

{"title":"A review of rheumatoid meningitis with case studies.","authors":"Merve Aktan Suzgun, Nursena Erener, Gokce Hande Cavus, Ayse Ozdede, Sabriye Guner, Serdal Ugurlu, Nil Comunoglu, Osman Kizilkilic, Sabahattin Saip","doi":"10.1093/mrcr/rxad010","DOIUrl":"10.1093/mrcr/rxad010","url":null,"abstract":"Rheumatoid arthritis (RA) is an autoimmune disease involving synovial joints, and it is known that extra-articular manifestations that may affect the central and peripheral nervous systems may develop during its course. Rheumatoid meningitis is very rare among all neurological involvements. In this study, cases diagnosed as rheumatoid meningitis with clinical, imaging, laboratory, and histopathological features are presented, and the aim of the study is to present current approaches in the diagnosis and treatment of rheumatoid meningitis in the light of case studies and current literature. The data of the patients who were followed up with the diagnosis of rheumatoid meningitis in neurology clinic between 2017 and 2021 were reviewed retrospectively. Three cases diagnosed with rheumatoid meningitis are presented in detail. In the first case, the diagnosis was reached by clinical, imaging, and laboratory findings as well as treatment response, while the diagnosis was made by histopathological verification in the second case. The third case shows that spontaneous remission can be observed in the course of rheumatoid meningitis. Rheumatoid meningitis, which is one of the rarest involvements in the course of RA, may present with headaches, focal neurological deficits, seizures, and altered consciousness. A meningeal biopsy is recommended when the differential diagnosis cannot be ruled out with imaging and laboratory findings. In the differential diagnosis Mucobacterium tuberculosis, syphilis, neuro-sarcoidosis, immunoglobulin G4-related disease, lymphoproliferative diseases, and systemic metastasis should be kept in mind. Aggressive RA management is recommended for treatment.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 2","pages":"340-346"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9670540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-TIF1γ antibody-positive dermatomyositis associated with nivolumab administration in a patient with advanced oesophageal squamous cell carcinoma: A case report and literature review. 晚期食管鳞状细胞癌患者抗tif1γ抗体阳性皮肌炎与纳武单抗相关:1例报告和文献综述

Modern Rheumatology Case Reports Pub Date : 2023-06-19 DOI: 10.1093/mrcr/rxad007

Takuya Sakurai, Junichiro Takahashi, Teppei Komatsu, Hidetaka Mitsumura, Yasuyuki Iguchi

引用次数: 0

Internet-based basic body awareness therapy in fibromyalgia syndrome: A report of three cases. 基于网络的基础身体意识治疗纤维肌痛综合征:附3例报告。

Modern Rheumatology Case Reports Pub Date : 2023-06-19 DOI: 10.1093/mrcr/rxad014

Özge Tahran, Burcu Ersöz Hüseyinsinoğlu, Günay Yolcu, Evrim Karadağ Saygı

{"title":"Internet-based basic body awareness therapy in fibromyalgia syndrome: A report of three cases.","authors":"Özge Tahran, Burcu Ersöz Hüseyinsinoğlu, Günay Yolcu, Evrim Karadağ Saygı","doi":"10.1093/mrcr/rxad014","DOIUrl":"https://doi.org/10.1093/mrcr/rxad014","url":null,"abstract":"Previous literature has shown that basic body awareness therapy (BBAT) may be an effective treatment for fibromyalgia syndrome (FMS). This study constitutes the first case study evaluating internet-based BBAT for FMS. The purpose of this case study was to describe the feasibility and preliminary outcomes of an internet-based BBAT training for a total of 8 weeks in three patients with FMS. The patients underwent a synchronous individual internet-based BBAT training. Outcomes were assessed using Fibromyalgia Impact Questionnaire Revised, Awareness-Body-Chart, Short-Form McGill Pain Questionnaire (SF-MPQ), and plasma fibrinogen level. These measures were administered at baseline and after the treatment. Patient satisfaction with the treatment was evaluated using a structured questionnaire. At the post-treatment evaluation, each patient showed improvements in all outcome measures. All patients had clinically significant changes in Fibromyalgia Impact Questionnaire Revised. The SF-MPQ total score in Patients 1 and 3 exceeded the minimal clinically important difference. All patients' pain severity exceeded the minimal clinically important difference for Visual Analogue Scale (SF-MPQ). Besides, we found some benefits in body awareness and the level of dysautonomia. At the end of the treatment, patient satisfaction with the programme was very high. Based on this case study, the application of internet-based BBAT seems feasible and promising for clinical benefits.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 2","pages":"464-469"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9724112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus. 妊娠期开始羟氯喹治疗可引起不良反应并改变妊娠结局:一例系统性红斑狼疮患者羟氯喹致急性全身性脓疱病。

Modern Rheumatology Case Reports Pub Date : 2023-06-19 DOI: 10.1093/mrcr/rxac089

Kotoi Tsurane, Kayoko Kaneko, Kazue Yoshida, Ryo Tanaka, Haruhiko Sago, Atsuko Murashima

{"title":"Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.","authors":"Kotoi Tsurane, Kayoko Kaneko, Kazue Yoshida, Ryo Tanaka, Haruhiko Sago, Atsuko Murashima","doi":"10.1093/mrcr/rxac089","DOIUrl":"https://doi.org/10.1093/mrcr/rxac089","url":null,"abstract":"Hydroxychloroquine (HCQ) is effective for treating a number of autoimmune diseases, including systemic lupus erythematosus. HCQ is generally safe and may be prescribed to pregnant women. Although current guidelines recommend initiating HCQ when considering pregnancy, the drug can cause adverse effects such as acute generalised exanthematous pustulosis (AGEP), which should be carefully evaluated. A 30-year-old pregnant woman with systemic lupus erythematosus at 16 + 5 gestational weeks was referred to National Center for Child Health and Development for persistent proteinuria and alopecia. Tacrolimus was initiated, and the dose of prednisone was increased. At 20 + 3 weeks of gestation, HCQ was administered to allow for a dose reduction of prednisolone. Proteinuria gradually improved as the pregnancy course stabilised. At 27 + 1 weeks of gestation, generalised pustular exanthema developed, presumably due to HCQ. Based on the clinical course and the analysis of the skin lesions, she was diagnosed to have either AGEP or generalised pustular psoriasis. Despite discontinuing HCQ, the skin lesions worsened dramatically, and infliximab therapy was required. After one course of infliximab treatment, exanthema gradually subsided. The final diagnosis was AGEP, based on the clinical course and pathological findings. At 30 weeks, pyothorax developed because of the pyogenic skin lesion and the compromised immune system, and long-term antibiotic therapy was required until 32 + 4 weeks, after which she underwent caesarean section. Although introducing HCQ is occasionally necessary during pregnancy, it is preferable to initiate HCQ in the preconception period and not after pregnancy because of the possible adverse effect, which can alter perinatal prognosis. Rheumatologists should consider the potential risks of HCQ.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 2","pages":"373-377"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9668284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A rare presentation of antisynthetase syndrome requiring intensive care in the midst of a COVID wave. 在COVID浪潮中罕见地出现需要重症监护的抗合成酶综合征。

Modern Rheumatology Case Reports Pub Date : 2023-06-19 DOI: 10.1093/mrcr/rxac088

Akhila Arya, Sanu Anand, Sandesh Kumar, Carl Britto

{"title":"A rare presentation of antisynthetase syndrome requiring intensive care in the midst of a COVID wave.","authors":"Akhila Arya, Sanu Anand, Sandesh Kumar, Carl Britto","doi":"10.1093/mrcr/rxac088","DOIUrl":"https://doi.org/10.1093/mrcr/rxac088","url":null,"abstract":"A 24-year-old female with pneumonia two months prior presented with fever, cough, and worsening dyspnoea in the midst of a COVID-19 spike. Her initial episode was treated as COVID-19 pneumonia. On presentation, her chest computed tomography was suggestive of bilateral lower zone organising pneumonia with mild fibrosis and was attributed to post-COVID sequelae with an infective exacerbation. Oral steroids and antibiotics were administered, following which she had initial improvement and then subsequent deterioration requiring intensive care unit (ICU) care. A detailed clinical examination (in-person and virtually) at this point revealed the presence of pigmented rashes over the knuckles and weakness of hip muscles. Laboratory work showed elevated creatine kinase levels and positive anti-Ro and anti-Jo1 antibodies, which pointed to a diagnosis of antisynthetase syndrome. Unique attributes of this case include younger age of presentation in an atypical ethnic group, which are possibly incited by COVID-19 infection in the peak of a COVID-19 wave. The work-up, diagnosis, and initial management of this patient were carried out through a hybrid ICU model, which functioned as a traditional ICU in the day and a tele-ICU at night with an appropriate network of subspecialists including rheumatologists consulting, thus highlighting a collaborative model in a low-resource setting capable of managing rare cases even in the midst of increasing critical care needs during the pandemic.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 2","pages":"394-398"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Giant cell arteritis with myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity in a patient with systemic sclerosis. 更正：一名系统性硬化症患者患有伴有髓过氧化物酶抗中性粒细胞胞浆抗体血清阳性的巨细胞动脉炎。

Modern Rheumatology Case Reports Pub Date : 2023-02-17 DOI: 10.1093/mrcr/rxad013

引用次数: 0

IgA vasculitis following COVID-19 vaccination. 新冠肺炎疫苗接种后IgA血管炎。

Modern Rheumatology Case Reports Pub Date : 2023-01-03 DOI: 10.1093/mrcr/rxac014

Naoya Nishimura, Yasuko Shiomichi, Satoshi Takeuchi, Shun Akamine, Reiko Yoneda, Seiji Yoshizawa

{"title":"IgA vasculitis following COVID-19 vaccination.","authors":"Naoya Nishimura, Yasuko Shiomichi, Satoshi Takeuchi, Shun Akamine, Reiko Yoneda, Seiji Yoshizawa","doi":"10.1093/mrcr/rxac014","DOIUrl":"10.1093/mrcr/rxac014","url":null,"abstract":"Abstract IgA vasculitis is generally triggered by infectious causes, but it has also been reported after immunization with various vaccines. Herein, we report two cases of IgA vasculitis after receiving the first or second dose of the Pfizer-BioNTech BNT16B2b2 mRNA vaccine. Two men, aged 22 and 30 years, developed palpable purpura on the extremities and arthritis. One patient also complained of fever and gastrointestinal symptoms. Laboratory findings revealed mild leukocytosis and slightly elevated C-reactive protein level, although platelet count and coagulation profile were within normal levels in both cases. Proteinuria and microhematuria were seen in one patient. Skin biopsies were performed in both patients and revealed leukocytoclastic vasculitis. The deposit of IgA and C3 was shown on immunofluorescence studies in one patient. Both patients were diagnosed with IgA vasculitis and treated with prednisolone, and their symptoms resolved within 1 week after initiation of treatment. The COVID-19 mRNA vaccine could trigger IgA vasculitis; however, a coincidence cannot be ruled out.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 1","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903512/pdf/rxac014.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Cardiomyopathy following COVID-19 vaccination in a patient with systemic lupus erythematosus. 系统性红斑狼疮患者COVID-19疫苗接种后的心肌病

Modern Rheumatology Case Reports Pub Date : 2023-01-03 DOI: 10.1093/mrcr/rxac070

Avreena Kaur Bhullar, Chew Zhi Chee, Ong Ping Seung, Khor Chiew Gek, Nor Hanim Mohd Amin

引用次数: 1

Septic arthritis induced by Streptococcus pneumoniae occurring in rheumatoid arthritis treated with abatacept and methotrexate: A case report. 类风湿关节炎合并阿巴接受和甲氨蝶呤治疗时肺炎链球菌引起的脓毒性关节炎1例。

Modern Rheumatology Case Reports Pub Date : 2023-01-03 DOI: 10.1093/mrcr/rxac072

Kazuya Abe, Yuichi Ishikawa, Tatsuro Takahashi, Michio Fujiwara, Yasuhiko Kita

{"title":"Septic arthritis induced by Streptococcus pneumoniae occurring in rheumatoid arthritis treated with abatacept and methotrexate: A case report.","authors":"Kazuya Abe, Yuichi Ishikawa, Tatsuro Takahashi, Michio Fujiwara, Yasuhiko Kita","doi":"10.1093/mrcr/rxac072","DOIUrl":"https://doi.org/10.1093/mrcr/rxac072","url":null,"abstract":"Septic arthritis occurs more frequently in elderly patients with rheumatoid arthritis (RA), with Staphylococcus aureus being the most common aetiologic agent. Rarely, Streptococcus pneumoniae (pneumococcus) is the cause of septic arthritis. Biological disease-modifying antirheumatic drugs (bDMARDs) are widely used in RA, but it is unknown whether bDMARDs could be a risk factor for pneumococcal septic arthritis in such patients. Here, we report the case of a patient with RA treated with bDMARDs (abatacept) who developed pneumococcal septic arthritis. The patient is a 64-year-old female complicated with RA for >10 years. She was treated with abatacept and methotrexate and has been in remission for 2 years. She had not received any pneumococcal vaccination. She consulted at our hospital for left ankle arthralgia and fever. Blood culture and puncture of the left ankle joints detected pneumococcus, and the pneumococcal urine antigen test was positive. The patient was diagnosed with pneumococcal septic arthritis, and she recovered after the administration of antibiotics. This is the first case report discussing these circumstances, suggesting that bDMARDs may be a risk of pneumococcal septic arthritis in patients with RA. To prevent this, pneumococcal vaccination should be encouraged in such patients. Furthermore, if RA is in remission, we may consider the spacing or withdrawal of bDMARDs to avoid severe infection.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 1","pages":"39-42"},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10852942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A case of C-ANCA-positive systematic lupus erythematous and ANCA-associated vasculitis overlap syndrome superimposed by COVID-19: a fatal trio. c - anca阳性系统性红斑狼疮和anca相关血管炎重叠综合征叠加COVID-19病例:致命的三人组

Modern Rheumatology Case Reports Pub Date : 2023-01-03 DOI: 10.1093/mrcr/rxab007

Baharnaz Mashinchi, Armin Aryannejad, Mansoor Namazi, Soroush Moradi, Zahra Masoumi, Amirhossein Parsaei, Maryam Masoumi

{"title":"A case of C-ANCA-positive systematic lupus erythematous and ANCA-associated vasculitis overlap syndrome superimposed by COVID-19: a fatal trio.","authors":"Baharnaz Mashinchi, Armin Aryannejad, Mansoor Namazi, Soroush Moradi, Zahra Masoumi, Amirhossein Parsaei, Maryam Masoumi","doi":"10.1093/mrcr/rxab007","DOIUrl":"https://doi.org/10.1093/mrcr/rxab007","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) poses a substantial challenge for rheumatologists and rheumatologic patients. They are concerned about the reciprocal interaction between connective tissue diseases, such as systemic lupus erythematosus (SLE), and the virus. Here, we report a 21-year-old female SLE patient presented to the emergency department with gastrointestinal symptoms and kidney involvement evidence. Based on the pathology and laboratory assessments, she was suspected of C-antineutrophil cytoplasmic antibody (ANCA) positive SLE and ANCA-associated vasculitis overlap syndrome (SLE/AAV OS), and plasmapheresis was performed every other day due to this diagnosis alongside the high titer of C-ANCA. We also administered methylprednisolone [1 g/day, intravenous (IV)] for 3 days, followed by dexamethasone with the maintenance dosage (1 mg/kg/day, IV). Although the patient's general condition improved the next days, her condition deteriorated suddenly on the 7th day of hospitalisation. She got intubated and went to the intensive care unit. Despite taking possible measures to manage the patient's condition, she eventually passed away due to severe acute respiratory distress syndrome, triggered by COVID-19. The distinct role of C-ANCA in SLE/AAV vascular damage and activating neutrophil cytokine release accompanied by the impaired immune system while facing COVID-19 seems to lead to increased morbidity and mortality in such patients. This report is presented to bring into consideration the possible role of C-ANCA in the prognosis of COVID-19 in SLE/AAV OS patients.","PeriodicalId":18677,"journal":{"name":"Modern Rheumatology Case Reports","volume":"7 1","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499895/pdf/rxab007.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4