Ministry of Science and Technology, Vietnam最新文献

{"title":"Synthesis of tetrahydroquinoline derivatives re-sensitising methicillin-resistant Staphylococcus aureus to cefuroxime","authors":"Tinh Luong, Thanh Thao Vu, Vu H. Nguyen, Ngoc Chau Tran","doi":"10.31276/vjst.67(9).48-54","DOIUrl":"https://doi.org/10.31276/vjst.67(9).48-54","url":null,"abstract":"The methicillin-resistant Staphylococcus aureus (MRSA) infections are becoming more and more difficult to treat due to the reduced number of effective antibiotics available.The restoration of antibiotic sensitivity to drugresistant bacterial strains by antibiotic adjuvants is a potent strategy.Six tetrahydroquinoline derivatives (1)-(6) were synthesised based on a nucleophilic substitution reaction (S N ).The structures of the studied compounds were elucidated by spectroscopic methods.The cefuroxime adjuvant activity was investigated using the broth microdilution method against 3 MRSA strains: ATCC 33591 and two clinical strains (MRSA 29 and MRSA 84), which were isolated from human nasal cavities at Clinical Department 3, Ho Chi Minh City Hospital of Dermato Venereology, from June to September 2022 (in accordance with the Ethics Committee approval No. CAIN457F2342).The fractional inhibitory concentration (FIC) value of the potential combination was determined according to the checkerboard method.At a concentration below 1/4 of the minimum inhibitory concentration (MIC), compounds (1) and (3) demonstrated synergistic action with cefuroxime on two clinical strains, 29 and 84.Structure activity relationship study suggests that tetrahydroquinoline derivatives containing an ortho-substituted benzyl group have the ability to sensitise MRSA to cefuroxime.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":"67 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://b.vjst.vn/index.php/ban_b/article/download/3688/1788/10635","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147916479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the causal relationship and optimise the extraction procedure of herbal preparation from Herba Mimosae pudicae, FoliumErythrinae variegatae, Cortex Cinnamomiiners andHerbaet radixScopariae","authors":"Oanh Hoang Hua, Van-Thi-Thanh Nguyen, Nam Phan, Kiet-Khang Chung, Quyen-Hong-To Duong","doi":"10.31276/vjste.2024.0102","DOIUrl":"https://doi.org/10.31276/vjste.2024.0102","url":null,"abstract":"Herbal preparations from four herbs -Mimosa pudica, Erythrina variegata, Scoparia dulcis, and Cinnamomum iners -exhibit sedative effects, treat insomnia, and effectively reduce anxiety and depression.The chemical components present in these medicinal herbs, such as mimosine and coixol, are biologically active substances.This study investigates the causal relationship and optimises the extraction procedure to achieve higher extraction efficiency.Fourteen experiments were designed using Design-Expert software to evaluate the influence of three independent variables (number of extractions, extraction time, and solvent-to-material ratio) on four dependent variables (extraction efficiency of mimosine, extraction efficiency of coixol, total extraction efficiency, and production cost).The content of mimosine and coixol was determined using the high-performance","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":"Online First 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://vietnamscience.vjst.vn/index.php/vjste/article/download/1293/538/2597","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147886469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating climate change-related perceptions that hinder stakeholders’ willingness to protecttheocean","authors":"Phuong-Tri Nguyen, Minh-Phuong Thi Duong, Hong-Hue Thi Nguyen, A.I. for Social Data Lab (AISDL), Vuong & Associates, Yen Nghia Ward, Ha Dong District, Hanoi, Vietnam, Viet‐Phuong La, A.I. for Social Data Lab (AISDL), Vuong & Associates, Yen Nghia Ward, Ha Dong District, Hanoi, Vietnam, Minh‐Hoang Nguyen, A.I. for Social Data Lab (AISDL), Vuong & Associates, Yen Nghia Ward, Ha Dong District, Hanoi, Vietnam, Quan‐Hoang Vuong, A.I. for Social Data Lab (AISDL), Vuong & Associates, Yen Nghia Ward, Ha Dong District, Hanoi, Vietnam","doi":"10.31276/vmostjossh.2024.0014","DOIUrl":"https://doi.org/10.31276/vmostjossh.2024.0014","url":null,"abstract":"While community and stakeholder support for marine and coastal ecosystem conservation policies is important, there is a shortage of multinational studies examining how perceptions of climate change impact stakeholders' willingness to protect the ocean.Therefore, this study, employing Mindsponge Theory and Bayesian Mindsponge Framework analytics, examines which climate change-related perceptions can hinder the willingness to support marine protection efforts, addressing a gap in existing literature.Our findings reveal that perceived high socio-economic costs for climate change mitigation (i.e., society is doing too much to address climate change and responses to climate change can damage the country's economy) and high potential of technologies in addressing climate change (i.e., new technologies can solve climate change) can hinder stakeholders' willingness to support ocean protection actions.Based on these results, we suggest a comprehensive strategy supporting climate change mitigation, marine conservation, and socio-economic growth simultaneously.The study also highlights the danger of exceptionalism, which refers to the risky tendency of relying too heavily on technology to solve environmental challenges, posing a significant risk to both climate change mitigation and marine protection efforts.We propose fostering collaborative partnerships, incorporating indigenous knowledge, and promoting ecocentrism to ensure globally informed, locally relevant, and impactful marine conservation.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":"online first 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://vmostscience.vjst.vn/index.php/vmost_jossh/article/download/378/352/1564","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147882462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of TiO2 and temperature on fabrication of porous Al2O3- based porous ceramic by pressureless sintering","authors":"Minh Hong Duong, Chu Hoàng Hà, Vietnam Industry Agency, Ministry of Industry and Trade, 54 Hai Ba Trung Street, Tran Hung Dao Ward, Hoan Kiem District, Hanoi, Vietnam, D. Nguyen, Trong Nghia Vu, Xuan Truong Nguyen, Quoc Khanh Dang, Thi Thao Nguyen","doi":"10.31276/vjst.66(10db-hh).02-07","DOIUrl":"https://doi.org/10.31276/vjst.66(10db-hh).02-07","url":null,"abstract":"","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":"66 10DB-HH","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://b.vjst.vn/index.php/ban_b/article/download/3031/1587/9118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147912480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification of catalpol in root of Rehmannia glutinosa varieties 19 collected in Phu Tho province by high-performance liquid chromatography","authors":"Thanh Loan Pham","doi":"10.31276/vjst.66(3).20-24","DOIUrl":"https://doi.org/10.31276/vjst.66(3).20-24","url":null,"abstract":"The active ingredient catalpol in the Rehmannia glutinosavariety 19 roots is an important chemical component. Catalpol has hypoglycemia, diuretic, and laxative effects; it is used to support the treatment of diabetes, ischemic cerebral, and dementia, and it is regulated by Vietnamese Pharmacopoeia V (2017) as a marker to check the quality of medicinal herbs. This study aimed to develop a procedure for quantifying catalpol in the root of Rehmannia glutinosa varieties 19 by high-performance liquid chromatography (HPLC) to evaluate the quality of medicinal herbs. The research results have selected suitable chromatographic conditions using the Gemini C18 column (250x4.6 mm, 5 μm), detector at 210 nm, mobile phase acetonitrile - phosphoric acid 0.1%, and flow rate at 0.6 ml/min. The peak area and catalpol concentration have a strong linear correlation with r=0.9999, Y = 21887X + 26213. The procedure has good accuracy and repeatability with a relative standard deviation (RSD) <2%. Quantitative results of catalpol in the root of the R. glutinosa varieties 19 reached 1.25%. The HPLC method is suitable for quantifying catalpol in the root of R. glutinosa varieties 19.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphology, anatomy, and quantitative determination of corosolic acid in Lagerstroemia calyculata Kurz in the Southeast region, Vietnam","authors":"Minh Tu To, Thi Xuyen Do, Thi Tuyet Hoang, Van Truong Phan, Minh Tu Dang, Thanh Huyen Pham","doi":"10.31276/vjst.66(3).25-30","DOIUrl":"https://doi.org/10.31276/vjst.66(3).25-30","url":null,"abstract":"Objectives: To describe the morphological characteristics, anatomy (stem, leaves), and quantify the corosolic acid in the leaves of Lagerstroemia calyculata Kurz collected in the Southeast region, Vietnam. Subjects and methods: Using the comparative morphological method to determine the scientific name of species. Studying the microscopic characteristics of Lagerstroemia calyculataKurz according to the research method of N. Ba (2009) [1] and quantifying the content of corosolic acid in the leaves according to the United States Pharmacopeia 2017 (USP 40), with adjustments to suit the conditions of the laboratory. Results: Lagerstroemia calyculata Kurz is tree, deciduous, height 30-35 m, smooth bark. Leaves lanceolate, lateral veins 9-11 pairs, hairy. Inflorescence paniculate, small white flowers. Capsules ovoid, 6-valved. Seeds are numerous, brown, and smooth. The stem has a bicollateral vascular bundle, conduction tissue arranged continuously, double phloem pillars and leaf veins exposed on both sides. The outer epidermis has multicellular stellate hairs. Scattered in soft tissue there are crystalline particles. Stomata are present only on the underside of leaves. The quantification of corosolic acid in three leaf samples of Lagerstroemia calyculata Kurz was from 0.05 to 0.12%. Conclusions: This study has detailed morphological, anatomical characteristics, and quantitative determination of corosolic acid in three leaf samples of Lagerstroemia calyculata Kurz collected in the Southeast region.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of solid-phase extraction materials from ion liquids for the analysis of carbamate pesticide","authors":"Van Duy Le, Thai The Nguyen, Hoang Phuong Tran, Anh Mai Nguyen","doi":"10.31276/vjst.66(3).45-54","DOIUrl":"https://doi.org/10.31276/vjst.66(3).45-54","url":null,"abstract":"In this study, ionic liquid immobilised onto silica gel material SiO2-(CH2)3-N(Oct)3Br was successfully synthesised and characterised by Fourier-transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). This material was applied as the stationary phase of solid-phase extraction for the enrichment of trace amounts of carbamate pesticides in water. The cartridge was eluted with 5 ml of acetonitrile (ACN), blow-dried with nitrogen gas, and re-dissolved in ACN:H2O (40:60, v/v) and analysed by high-performance liquid chromatography - ultraviolet (HPLC-UV) at 210 and 245 nm. Within this process, elution of the cartridge with 5 ml of acetonitrile (ACN) was followed by nitrogen gas blow-drying and subsequent re-dissolution in ACN:H2O (40:60, v/v), culminating in analysis by HPLC-UV at 210 and 245 nm. Optimisation of conditions facilitated the analysis of carbamate pesticides, with the limit of quantitation (LOQ)ranging from 0.36-2.00 μg/l for tap water and 0.4-3.5 μg/l for river water. Furthermore, the method exhibited favourable repeatability, with a relative standard deviation (RSD) of less than 10%, thereby meeting the Association of Official Analytical Collaboration (AOAC) standards.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of geomechanical changes in faulted rock mass around underground structures subjected to earthquakes","authors":"Q. Nguyen, Ngoc Hue Nguyen, Quang Minh Nguyen, V. Nguyen, Tuan Minh Tran","doi":"10.31276/vjst.66(3).13-19","DOIUrl":"https://doi.org/10.31276/vjst.66(3).13-19","url":null,"abstract":"Faults are a type of geological structure that often leads to geological disasters in underground structures under normal conditions and especially when earthquakes occur, thereby requiring careful study.This article introduces some numerical simulation results on the seismic wave propagation process, on changes in stress and displacement states in the rock mass with a small fault of a dip angle of 45o, around a circular cross-section tunnel, using the discrete element method (Universal distinct element Code - UDEC). Three cases are simulated: a) The tunnel is located in the hanging wall rock, the fault is located 10m from the centre of the tunnel on the vertical axis; b) The fault runs through the centre of the tunnel and c) The tunnel is located in the footing wall rock, the fault is located 10m from the centre of the tunnel on the vertical axis. The results obtained show a very clear influence of the position and location of the fault on the geomechanical changes in the rock mass around the tunnel, contributing to the reasonable design of tunnels subjected to earthquakes.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of TiO2 by hydrothermal method using deep eutectic solvent for application in dye-sensitised solar cell","authors":"Doan Thanh Thuy Nguyen, De Nguyen, Huynh Trung Le Ly, Tuyet Phuong Nguyen","doi":"10.31276/vjst.66(3).06-12","DOIUrl":"https://doi.org/10.31276/vjst.66(3).06-12","url":null,"abstract":"Raw TiO2 powder from a commercial source was used as a precursor in the hydrothermal process with deep eutectic solvent (DES) of choline chloride and urea with a molar ratio of 1:2 at different temperatures and interval times. The synthesised TiO2 was further utilised to produce diffracting TiO2 paste for application in dye-sensitised solar cells (DSCs) to improve the power conversation efficiency of devices. The TiO2 product analysed by X-ray diffraction (XRD) showed a similar phase and crystallinity to the raw material. However, scanning electron microscope (SEM) images showed that the hydrothermal TiO2 product had less particle aggregation than the raw one. The particle size was exceedingly 100 nm. The TiO2 pastes were prepared with a mixture of ethyl acetate and terpineol at volume ratios of 3:7 and 4:6. The paste was suitable to make thin films by the screen-printing method as a diffusion layer in cells. DSC devices using the TiO2 produced by the hydrothermal process with DES at 140oC for 18, 24, and 36 hours, respectively, enhanced the power conversion efficiency by 6.7-6.9%, which was higher than the ones using raw TiO2 by about 7%. Therefore, TiO2 powder modified by the hydrothermal process in DES solvent has great potential for application in DSC manufacture.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 60","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research and development of a predictive system for fall armyworm early warning on maize crop","authors":"Thi Diep Hoang, Thi Anh Duong Nguyen, Kien Thai Duong Nguyen, Duy Vu Nguyen, Thi Quynh Trang Luu, Thi Thu Phuong Tran, Minh Trien Pham","doi":"10.31276/vjst.66(3).38-44","DOIUrl":"https://doi.org/10.31276/vjst.66(3).38-44","url":null,"abstract":"The rapid increase in fall armyworms (FAW, Spodoptera frugiperda) in recent years has posed major challenges to maize growers around the globe. To keep larval density below the economic threshold, we need interdisciplinary agricultural solutions like plant protection epidemiology, the Internet of Things, and scientific data techniques for early detection, monitoring, forecasting, and making informed decisions. Pest control should be planned ahead of time to prevent indiscriminate pesticide spraying, waste, and a negative effect on the environment. In this study, the authors plan to create a comprehensive iFAWcast software system that will automatically predict, alert, and gather research data on fall armyworms on maize crops in Vietnam. The system is comprised of three major components: (i) An automatic forecasting and alerting tool for fall armyworm outbreaks on the web platform; (ii) An agriculture reporting, forecasting, alerting, and user management tool on the web platform; and (iii) A mobile app that provides forecasting and alerting services on fall armyworms to farmers based on their geographical location. The iFAWcast system includes a central computation that dynamically updates weather forecasts from the Visual Crossing API and the OpenWeatherMap API, as well as a formula for the effective cumulative temperature based on the characteristics of fall armyworms on maize crops in Vietnam. The developed system was tested using data collected straight from the field, yielding extremely accurate and dependable results.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}