Study on the causal relationship and optimise the extraction procedure of herbal preparation from Herba Mimosae pudicae, FoliumErythrinae variegatae, Cortex Cinnamomiiners andHerbaet radixScopariae

Abstract

Herbal preparations from four herbs -Mimosa pudica, Erythrina variegata, Scoparia dulcis, and Cinnamomum iners -exhibit sedative effects, treat insomnia, and effectively reduce anxiety and depression.The chemical components present in these medicinal herbs, such as mimosine and coixol, are biologically active substances.This study investigates the causal relationship and optimises the extraction procedure to achieve higher extraction efficiency.Fourteen experiments were designed using Design-Expert software to evaluate the influence of three independent variables (number of extractions, extraction time, and solvent-to-material ratio) on four dependent variables (extraction efficiency of mimosine, extraction efficiency of coixol, total extraction efficiency, and production cost).The content of mimosine and coixol was determined using the high-performance