Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)最新文献

{"title":"Correlation between the Characteristics and Quality of Life of Hypertensive Outpatients at a Private Hospital in Yogyakarta","authors":"Faridah Baroroh, A. Sari","doi":"10.2991/adics-phs-19.2019.30","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.30","url":null,"abstract":"Many factors can affect a person’s quality of life, including therapy with antihypertensive drugs that often have uncomfortable side effects and lead to decreased quality of life. This study aimed to determine the statistical relationship between the characteristics and quality of life of hypertensive outpatients at a private hospital in Yogyakarta, Indonesia. This cross-sectional study used the EQ5D questionnaire to measure the quality of life of 56 respondents, who had met the inclusion criteria, after three months of antihypertensive therapy. The data were processed by scoring the questionnaire items and then converting the EQ5D dimensions to EQ5D Index based on the Malaysian value set. The data analysis also included descriptive statistics andchi-square test. The results showed that the quality of life, as represented by the EQ-5D index, ranged from 0.375 (lowest) to 0.933 (highest). The severe problems in the quality of life were identified in three dimensions, namely anxiety/ depression (7.14%), pain/discomfort (5.36%), and usual activities (3.57%). Meanwhile, difficulties were not found in the other two dimensions, namely self-care (89.29%) and mobility (55.36%). The results showed that the patients’ characteristics, namely sex, age, employment, education, and complication, correlated with quality of life at different levels (p-values), i.e., 0.350, 0.418, 0.992, 0.726, and 0.099, respectively. As a conclusion, there is no significant relationship between patients’ characteristics and quality of life (p-values> 0.05). Keywords—characteristics, quality of life, hypertensive, outpatient.","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121143276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Pharmacoepidemiology Study of Antihypertensive and Antidiabetes Mellitus Drug in DM-Hypertensive Outpatient in a Private Hospital","authors":"A. Akrom, Muna Marzuqoh","doi":"10.2991/adics-phs-19.2019.10","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.10","url":null,"abstract":"","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122047357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causative Microorganism of Pneumonia and Antibiotics Sensitivity Pattern on Teaching Hospital in Surakarta, Indonesia","authors":"Yeni Farida, M. Hanafi, M. Maryani, Qisty A Khoiry, Hesti Diah Prahastiwi","doi":"10.2991/adics-phs-19.2019.2","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.2","url":null,"abstract":"Pneumonia still remains as a significant cause of mortality due to the virulence factors of the causative microorganism. The causative microorganism profile of pneumonia differs from one region to another. This study aimed to identify the etiology of pneumonia and bacterial sensitivity pattern to antibiotics. A cross-sectional study was conducted based on reports of bacteria isolates from the ward of Teaching Hospital, from May to October 2018. Microbiological isolates were collected from sputum patient. Identification of all causative microorganisms was performed by standard microbiologic methods. Susceptibility testing was performed using disk diffusion method. Among 47 patient, the subject was dominated by a male (51%) with mean age was 57±2.22. Streptococcus pneumoniae was the most common causative agent (28%) followed by Candida sp. (21%), Pseudomonas aeruginosa (8.8%), Klebsiella pneumoniae (8.8%) and Streptococcus viridans(8.8%). S pneumonia was sensitive to Levofloxacin (81.25%); Ceftriaxone (62.5%); and Ampicillin (75%). Cefoperazone was the only antibiotics showed high effectiveness against P. aeruginosa (83.3%) and K. pneumoniae (100%). Antibiotics susceptibility pattern surveillance should be done periodically. Keywords—antibiotics, causative microorganism, pneumonia, sensitivity pattern","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133709894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation of Actinomycetes from Sugarcane (Saccharum officinarum) Rhizosphere and the Ability to Produce Antibiotic.","authors":"N. Aini, N. Sulistyani","doi":"10.2991/adics-phs-19.2019.3","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.3","url":null,"abstract":"Actinomycetes are well-known microorganism as secondary metabolites producers which serve as antibiotics. In this study, sugar cane (Saccharum officinarum) rhizosphere soil samples were collected from Piyungan, Bantul, Yogyakarta. The aims of this study were to obtain Actinomycetes isolates from sugar cane (Saccharum officinarum) rhizosphere which potentially produce antibiotics and to analyse the Thin Layer Chromatography (TLC) profile of ethyl acetate extract of active Actinomycetes isolates. The method used in primary screening to evaluate Actinomycetes antibacterial activity from the sugar cane rhizosphere are agar block method and cup-plate method, and the extract activity assay used Kirby-Bauer method. Determination of antibiotic activity was observed by measuring the diameter of inhibition zone. Extract component was analyzed by Thin Layer Chromatography (TLC). The results of this research was found 39 isolates of Actinomycetes classified into 7 groups based on color grouping. The result of agar block test was revealed that among 39 isolates, four isolates (10.25%) were able to inhibit Staphylococcus aureus. They were Te.234, Te.235, Te.236, and Te.325 isolates. Inhibition zone of crude extracts from these isolates against Staphylococcus aureus were Te.234=7.67 mm, Te.235=3.75 mm, Te.236=12.42 mm, and Te.325=19.16 mm. However, none of these isolates were able to inhibit Escherichia coli. Results of TLC profile showed that the suspected compounds contained in ethyl acetate extract of culture broth are alkaloid, polypeptide, steroid, alcohol, phenol and ketone/aldehyde compounds. Based on the results, it can be concluded that Actinomycetes can be isolated from sugar cane rhizosphere which has potential as an antibiotic producer by narrow spectrum to inhibit Gram-positive bacteria such as Staphylococcus aureus. Keywords—actinomycetes, isolation, rhizosphere, antibiotic, sugar cane, TLC profile","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114479620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technical Efficiency of Maternal and Child Health Program at Public Health Center in Indonesia","authors":"Dedik Sulistiawan, Insan Rekso Adiwibowo, M. F. Kurniawan, L. Trisnantoro, W. Budiarto","doi":"10.2991/adics-phs-19.2019.26","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.26","url":null,"abstract":"The limited availability of health resources in the high public demand requires the health programs and service providers, especially in Public Health Center (Puskesmas) to make efficiency. This study aims to provide information about the level of technical efficiency of Puskesmas in Indonesia in organizing the Maternal and Child Health (MCH) program. This study also tries to investigate several factors that contribute to the level of Puskesmas efficiency in organizing MCH programs. This study was quantitative research with cross-sectional approach. This study used secondary data derived from Health Financing Research (Health Financing Research: RPK) in 2015 for Puskesmas level. The data analyzed by the non-parametric technique using DEAP software version 2.1 to obtain technical efficiency score of each Puskesmas. After getting the technical efficiency score, the researchers conducted multivariate analysis using Tobit Regression, with the dependent variable was technical efficiency score of MCH program and predictors were the category of public health development index, fiscal capacity index, financial management authority status (BLUD status), geographical status, and region category. The technical efficiency of the MCH program at Puskesmas level was 0.81 ±0.12. The efficiency scores were affected by geographic areas-where urban Puskesmas were more efficient than rural and remote areas-and regional fiscal capacity-where Puskesmas in areas with high fiscal capacity were more efficient than Puskesmas in areas with medium and low fiscal capacity. Areas with geographic limitations require more considerable health resources to obtain the same output than areas with more comfortable geographic conditions. Keywords—technical efficiency, data envelopment analysis, input-output","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120938571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Adsorption and Reduction of Au(III) on Esterified Humic Acid","authors":"Dian Prasasti, S. J. Santosa, S. Sudiono","doi":"10.2991/adics-phs-19.2019.5","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.5","url":null,"abstract":"Electronic waste is increasing every year, one of which is electronic waste metal. Gold mining is less profitable than taking gold from electronics. One of the adsorbents that can be used is humic acid. To study the effect of functional groups on the adsorption of Au (III) ions, the adsorptionreduction of Au (III) ions using esterified humic acid was studied. Humic acid that will be esterified is isolated from peat soil from Rawa Pening, Central Java. Esterification was performed by reaction with ethanol in acidic conditions and doing repeated. Estesterified humic acid was characterized by Fourier-Transform Infrared spectroscopy (FTIR), X-Ray Diffraction (XRD), ash content, total acidity, -COOH content, and -OH content, then used for adsorption-reduction of Au (III). Esterified humic acid has studied the effect of pH adsorption, adsorption kinetics, and adsorption isotherm on adsorption reduction process of Au (III). The Au metal formed was confirmed by XRD diffractogram and photo-optical microscope. Esterified humic acid has 0.78% ash content, total acidity of 1022 cmol/kg, COOH content of 217 cmol/kg, and OH content of 805 cmol/kg. pH optimum on adsorption reduction Au(III) using esterified humic acid was 6. The adsorption capacity is 625 mg/g with Langmuir isotherm model esterified humic acid. The adsorption rate constant (k) is 1.50.10-3 g/mg min with Ho kinetic model for esterified humic acid. Peaks of gold particles in the diffractogram are detected on 2θ = 38, 44, and 64. Keywords—adsorption, reduction, Au (III), humic acid, esterification","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122768779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Gotu Kola (Centella asiatica) Extract Toward Expression of Caspase 3 of Hippocampus Pyramidal Cells on Dementia Model Rats Induced by Trimethyltin.","authors":"S. Yuliani, Nikmawati Linar","doi":"10.2991/adics-phs-19.2019.12","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.12","url":null,"abstract":"Hippocampus is part of brain that has an important role in the process of memory. Hippocampus is very sensitive to oxidative stress. Oxidative stress in the hippocampus can cause apoptosis of neurons associated with the pathogenesis of dementia. Gotu kola (Centella asiatica) has antioxidants effect that can prevent apoptotic cells. The aim of the study was to find out the effects of gotu kola extracts toward expression of caspase 3 in CA1 and CA2-CA3 regions of hippocampus on trimethyltin (TMT)-induced dementia rats. The rats were divided randomly into six groups consisting of 5 rats of each.The normal group was given oral CMC-Na solution and injection of 0.9% saline intraperitonealy (ip); the negative control group was given oral CMC-Na solution and TMT dissolved in 0.9% saline (ip); the positif control group was given oral 200 mg/kg body weight (bw) of citicoline solution and TMT; and the extract groups were treated with oral 100, 200, and 300 mg/kg bw, respectively, of gotu kola extract and TMT. The extract and citicoline solutions were given at day 1 up to day 35 of experiment, whereas the TMT chloride was injected as a single dose of 8 mg/kg bw at day 8 of experiment. On the 36 th day the rats were sacrificed. The hippocampus was taken to observe caspase 3 expression in CA1 and CA2-CA3 regions with immunohistochemical staining. The data of a percentage of the number of cells expressing caspase 3 in CA1 and CA2CA3 regions were statistically analyzed using one-way anova continued by Tukey-HSD test at significant level 0.05. The injection of TMT could signifcantly increase caspase 3 expression in the CA1 and CA2-CA3 regions of hippocampus. Administration of gotu cola extract dose 100, 200, and 400 mg /kg bw could reduce caspase 3 expression and significantly different compare to negative control. Gotu kola extract may have antiapoptotic effect on the hippocampal pyramidal cells of the dementia model rats induced by trimethyltin. Keywords—hippocampus, caspase 3, gotu kola (centella asiatica), dementia, TMT","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128774316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Complience of Hypertensive Patients in Health Center Pengasih I Kulon Progo","authors":"A. Sari, M. A. Cakrawardana","doi":"10.2991/adics-phs-19.2019.27","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.27","url":null,"abstract":"Hypertension is a condition where blood vessels have persistent high blood pressure. Compliance is a behavior to adhere to doctor's advice about using medicine. The purpose of this study is to determine the compliance, the use of antihypertensive and the relationship between characteristics of patients with their adherence in hypertensive patients in health center Pengasih I Kulon Progo period September-October 2018. This study used an observational analytic method with prospective cross-sectional approach. The inclusion criteria were male and female who hypertensive outpatients, aged 17-85 years old. Otherwise, the exclusion criteria were patient who had unconscious or mental disorders, complications of diabetes or coronary heart disease, gestational disease and using treatment for less than 3 months. Respondents will be given a MARS questionnaire. Data were analyzed statistically by SPSS using the Chi-square test with a confidence level of 95%. The results showed that 35 patient who compliance (36%) and 62 patient who non-compliance (64%). Hypertension drug treatment that used were Captopril 65 patients (67%) and combination of Captopril and Amlodipine 32 patients (33%). The respondent’s characteristics were obtained by female sex (73%), age range <55 years (42%), not working (32%), education level ≤ high school 94 patients (97%), and long suffering from hypertension <5 years (22%). Result from Chi Square test obtained that the value of p value> 0.05 which means there was no significant relationship between characteristics and compliance in the use of treatment for hypertension. Based on the results of the study, it can be concluded that 36% of patients adhere to taking drugs, and antihypertensive drug treatment which used are captopril and combination of captopril-amlodipine. There is no relationship between the characteristics of respondents and the adherence to their treatment. Keywords— hypertension, compliance, health center, MARS","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121392119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biscuits Substitution with Tempe and Catfish Flour Increase Birth Weight of Infants Born from Mothers with Chronic Energy Deficiency","authors":"S. Sunarti, M. Ahda, Ahmad Ahid Mudayana, Diva Hanim, K. Kusnandar, M. Angwar","doi":"10.2991/adics-phs-19.2019.24","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.24","url":null,"abstract":"Chronic energy deficiency (CED) and anemia in pregnant women, is still a significant public health problem in Indonesia. CED on pregnant women the risk of low birth weight on newborn. Tempe and catfish are available for daily consumption and rich in protein and Fe but has been understudied to prevent low birth weight in pregnant mothers with CED Objective: The study aims to investigate the effect of biscuits substitution from mixed soybean fermentation (Tempe) and catfish flour in increasing birth weight of infants born from mothers with CED. Methods: This was quasi-experimental design involving 62 pregnant mothers in third trimester, but 10 mothers discontinued participation. At the follow-up study, the intervention group comprised 26 mothers, whereas the control group included 26 mothers. The intervention group received daily biscuits substitution from mixed tempe and catfish flour (70 grams) during 60 days, whereas the control group received daily supplementary feeding according to the national standard. The research subject was monitored until delivery. MUAC and hemoglobin were remeasured at the end of the intervention (60 days). The data from both groups compared using independent sample t-test. Results: The average of infant birth weight in the intervention group (3163.46; 414.622) was higher than the control group (2680.77; 521.551), p 0.001. Biscuits substitution with soy bean fermented (tempe) and catfish flour increased the birth weight of infants born from mothers with CED and anemia. Therefore, these biscuits should be promoted to prevent low birth weight in babies born from mothers with CED and anemia. Keywords—low birth weight, biscuit, chronic energy def","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125542386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Amount of βCarotene, Total Phenolic and Total Flavonoid of Ethanol Extract of Leaf Moringa Oleifera with Variation Concentration of Solvent","authors":"N. Sugihartini, Dessy Erliani Mugita Sari, M. Bachri, S. Yuliani","doi":"10.2991/adics-phs-19.2019.22","DOIUrl":"https://doi.org/10.2991/adics-phs-19.2019.22","url":null,"abstract":"The use of Moringa leaves is increasing because it contains β carotene, phenolic compounds and flavonoids which are efficacious as antioxidants. The solvent concentration is a factor that affects the active content in the extract. This study aims to determine the effect of ethanol concentration on β carotene levels, total phenolic and total flavonoids in ethanol extract of Moringa leaves. In this study the variation of ethanol solvent concentration was 50%, 70% and 96% for extracting Moringa leaves by maceration method at a ratio of 1:40. The extract obtained was determined as β carotene levels by using HPLC, total phenolic content and total flavonoids contend by spectrophotometer. The results of each test were analyzed by using one-way ANOVA to see a significant difference between solvent concentrations for each test parameter. The test results showed that in each ethanol extract 50%, 70%, 96% had β carotene levels of 0.24 ± 0.01; 0.40 ± 0.00; 5.33 ± 0.15; total phenolic 122.26 ± 1.49; 132.54 ± 2.56; 84.62 ± 2.44; total flavonoids 2.51 ± 0.06; 5.03 ± 0.08; 13.15 ± 0.47, respectively. The highest solvent containing active ingredients is 96% ethanol. Keywords—moringa oleifera, β carotene, total phenolic, total flavonoid, solvent","PeriodicalId":186082,"journal":{"name":"Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121593674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}