Causative Microorganism of Pneumonia and Antibiotics Sensitivity Pattern on Teaching Hospital in Surakarta, Indonesia

Yeni Farida, M. Hanafi, M. Maryani, Qisty A Khoiry, Hesti Diah Prahastiwi
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Abstract

Pneumonia still remains as a significant cause of mortality due to the virulence factors of the causative microorganism. The causative microorganism profile of pneumonia differs from one region to another. This study aimed to identify the etiology of pneumonia and bacterial sensitivity pattern to antibiotics. A cross-sectional study was conducted based on reports of bacteria isolates from the ward of Teaching Hospital, from May to October 2018. Microbiological isolates were collected from sputum patient. Identification of all causative microorganisms was performed by standard microbiologic methods. Susceptibility testing was performed using disk diffusion method. Among 47 patient, the subject was dominated by a male (51%) with mean age was 57±2.22. Streptococcus pneumoniae was the most common causative agent (28%) followed by Candida sp. (21%), Pseudomonas aeruginosa (8.8%), Klebsiella pneumoniae (8.8%) and Streptococcus viridans(8.8%). S pneumonia was sensitive to Levofloxacin (81.25%); Ceftriaxone (62.5%); and Ampicillin (75%). Cefoperazone was the only antibiotics showed high effectiveness against P. aeruginosa (83.3%) and K. pneumoniae (100%). Antibiotics susceptibility pattern surveillance should be done periodically. Keywords—antibiotics, causative microorganism, pneumonia, sensitivity pattern
印尼泗水市教学医院肺炎病原微生物及抗生素敏感性分析
由于致病微生物的毒力因素,肺炎仍然是导致死亡的一个重要原因。肺炎的病原微生物特征因地区而异。本研究旨在确定肺炎的病因和细菌对抗生素的敏感性模式。根据2018年5月至10月教学医院病房的细菌分离报告进行横断面研究。从患者的痰中采集微生物分离株。所有病原微生物的鉴定采用标准微生物学方法进行。药敏试验采用纸片扩散法。47例患者中以男性为主(51%),平均年龄57±2.22岁。最常见的病原体是肺炎链球菌(28%),其次是念珠菌(21%)、铜绿假单胞菌(8.8%)、肺炎克雷伯菌(8.8%)和翠绿链球菌(8.8%)。S型肺炎对左氧氟沙星敏感(81.25%);头孢曲松钠(62.5%);氨苄青霉素(75%)。头孢哌酮是唯一对铜绿假单胞菌(83.3%)和肺炎克雷伯菌(100%)有效率的抗生素。应定期进行抗生素药敏型监测。关键词:抗生素;病原微生物;肺炎
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