MOJ proteomics & bioinformatics最新文献

{"title":"Development and validation of a scale to measure exposure to violence in mexican adolescents: exploratory and confirmatory factor analysis","authors":"J. Galán-Jiménez","doi":"10.15406/mojpb.2018.07.00248","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00248","url":null,"abstract":"In Mexico, the Instituto Nacional de Estadística, Geografía e Informática (National Institute of Statistics, Geography and Computing; INEGI, 2014) reported that 30.9% of the houses had at least one victim of violence. The Global Peace Index (2013; 2015) ranked Mexico in the 131st place in 2014 and then in the 144th place in 2015 out of 161 countries.1 proposed that living in violent communities is harmful, especially for children and adolescents. Describe that the exposure to violence is not only experienced by the victim when there is a direct exposure but can also be experienced by an observer; an indirect exposure.2 The indirect exposure can occur when one is a witness or simply by being informed of the violence experienced by others, which is also supported.3 Violence exposure rates from direct victims of violence in different populations range between 20% and 50%. Furthermore, 30% to 95% of people reported being exposed to indirect violence.4‒8 Adolescents exposed to high levels of violence show emotional numbing (less distress) and anxiety symptoms that worsen with violence exposure.9 suggest that witnessed violence could affect perception, behavior, emotions and physique.10 found that community violence has a “decidedly larger and more significant effect” (p. 329) on the aggression reported two years later.11 propose that witnessed or experienced violence “increases the risk of running away from home, leaving school, pregnancy, suicidal attempts, and having contact with the criminal justice system during adolescence” (p. 2).12 Exposure to violence is related to violent behavior, depression, anxiety, posttraumatic stress, self‒esteem, aggression, transgression, and constant exposure could make violence seem as acceptable, expected or normal. All of these consequences may be related to the proximity or closeness to the aggressor, duration of the exposure, social norms, and values.12‒16 There are some instruments measuring some aspects of violence. Proposed the Conflict in Adolescent Dating Relationship Inventory (CADRI).17 developed the Index of Spouse Abuse, which measured both the physical and non‒physical aspects and,18 behavioral control. It was validated with the Scale of Sexual Assertiveness, and its alpha reliability ranges between 0.60 and 0.81. proposed the Questionnaire of Violence between Couples with 5170 people participants in Spain, Argentina and Mexico.19 The questionnaire has eight factors, labeled as types of abuse: emotional punishment, coercion, detachment, physical, gender, humiliation, instrumental and sexual. The model explains 51.3% of variance and it reported alphas between 0.58 and 0.81. This questionnaire includes physical, psychological and sexual components of violence. Reported the Out‒group Threat Perception Scale’s validity and reliability coefficients.20 presented the Exposure to Insecurity and Violence Questionnaire for Adolescents, developed in Mexico to measure mild to severe violence.21 although the questi","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82684275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer burden in Nepal: a call for action","authors":"B. Saud, S. Adhikari, Mamata Sherpa Awasthi","doi":"10.15406/MOJPB.2018.07.00247","DOIUrl":"https://doi.org/10.15406/MOJPB.2018.07.00247","url":null,"abstract":"According to World Health Organization (WHO), 9.6 million people died of cancer in 2018 of which 70% were from middle and low‒income countries. Cancer is also the second leading cause of deaths globally. The leading causes of deaths due to cancer worldwide were highest for lung cancer, followed by colorectal cancer, stomach cancer, liver cancer and breast cancer.1 A report published by WHO has shown that cancer mortality in Nepal is higher in females as compare to males‒7,400 and 6,900 respectively. The major risk factors are tobacco smoking, excessive alcohol consumption, household solid fuel, physical inactivity and obesity,2 along with others like environment pollution and excessive pesticides in vegetable and fruits.3,4 Based on hospitals’ data approximately 8,000‒10,000 new cases of cancer are identified every year in Nepal.5 Kathmandu, the capital of Nepal has been listed on top of the 10 most cancer affected districts in Nepal followed by Sunsari, Morang, Chitwan, Jhapa, Lalitpur, Rupandehi, Kaski, Nawalparasi and Bhaktapur.6 A retrospective study analysis data over the four year period between 2010 and 2013 of twelve hospital situated in Nepal showed that cancer of bronchus and lung, stomach and larynx are most common among men. In female, most common cancers were listed to be cervical/ uteri, breast, bronchus and lungs.7 According to a study conducted in central region of Nepal, of total 240 cancer patients, Newar were 30.42%, Chhetri were 22.92% and Brahmin were 20%. Most of the cancer cases were documented from Kathmandu, Lalitpur, Bhaktapur and Sindhupalchowk districts.8 Showed the age specific incidence of cancer in central Nepal. They showed that rapid increase in incidence was among 45‒49age group in male and 30‒34age group in female, the highest incidence rate was between age groups 70‒74years in male and 65‒69 age group in female.9 By 2020 the incidence rate of cancer per 100,000 is estimated to be 41.4 in female and 38.5 in male.10 Annual report published by Department of Health Services (DoHS), Nepal in 2018 depicted the morbidity of various cancers in all seven provinces between 2016 and 2017. A total of 13,997 cases were reported in Out Patients Department (OPD) attending patients all over Nepal. 9053 cases of different cancers were reported from Province 3 and 3865 from Province 4. The least number of cases were reported from Province 6 (70 cases). The higher number of cases reported in Province 3 and 4 may be due to easier accessibility to higher health care facilities and very low numbers in province 6 due to inaccessibility to better health care facilities. Overall, highest morbidity was noted for Breast and Lung cancer, 1863 and 1885 respectively, followed by Cervical/Uteri Cancer‒1425, Head and Neck Cancer‒866 all over Nepal as shown in Figure 1.11 Screening and early detection facilities are limited to the central cities of the nation. The rural communities are deprived of screening facility in primary public health ca","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85447531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal potential of some medicinal plants on selected pathogenic fungi","authors":"I. Umaru, Fasihuddin A. Badruddin, H. Umaru, K. I. Umaru","doi":"10.15406/MOJPB.2018.07.00246","DOIUrl":"https://doi.org/10.15406/MOJPB.2018.07.00246","url":null,"abstract":"Medicinal plants represent a rich source of antimicrobial agents. Plants are used medicinally in different countries and they are source of many potent and powerful drugs. A wide range of medicinal plant parts is used for extract as raw drugs. They possess varied medicinal properties, while some of these raw drugs are collected in small quantities by the local communities and traditional healers for local use.1 The plants represent a rich source iiof antimicrobial agents.2,3 Many of the plant materials used in traditional medicine are readily available in rural areas at relatively cheaper than modern medicine.4‒6 The activity of plant extracts on bacteria and fungi has been studied by a very large number of researchers in different parts of the world.7‒9 The plant metabolites and plant based pesticides appear to be one of the better alternatives as they are known to have minimal environmental impact and danger to consumers in contrast to the synthetic drugs.10,11 Leptadenia hastata (Pers) Decne (Family‒Asclepiadaceae), commonly known as hastata is edible non‒domesticated vegetable and it is collected in wild throughout Africa. It is a voluble herb with creeping latex stems, glabescent leaves, glomerulus and racemus flowers as well as follicle fruits. It is typically grown in tropical dry lands in sandy soil. Wild foods like Leptadenia hastata provide food security during seasonal changes and are used medicinally in many areas. The breeders commonly used the leaf and stems for their parasitic activity and against placental retention.12 This plant can be used as a probiotic supplements and foods to lower risk of infections, improved digestion and even a reduced risk for some chronic diseases as claimed by traditional healer.12 However, Barringtonia racemosa are mangrove plants. This specie which is also known as putat, fish poison tree or powder puff tree is a type of highly valuable plant species due to its medicinal values. They are geographically found to be widely distributed from eastern Africa and Madagascar to Micronesian, Asia and Polynesian Island, the species was said to have been associated very well in various tribes around the world with diverse ethno‒botanical uses. The therapeutic potential of this herb is as a result of the presence of diverse bioactive compounds such as Lupeol, Germanicol, Teraxanol Barringtogenic, Barringtogenol etc. However, most of the studies on Barringtonia racemosa are restricted to crude extracts, and many biologically active compounds are yet to be identified in order to claim the traditional uses of this","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81250919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of prevalense external parasite on different species","authors":"Kindu Wondmnew, Mohamed A. M. Hussien, W. Temesgen, Dagnachew Endalamaw","doi":"10.15406/mojpb.2018.07.00245","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00245","url":null,"abstract":"Ethiopia has the largest livestock inventories in Africa including about 40.7millions cattle, 25.5millions sheep and 23.4million goats (CSA. 2004). Its resource of cattle, sheep, and goats ranks 1st, 3rd and 2nd respectively in Africa.1 The development of leather industry requires great quality of raw materials of various origins, the principal source of which is livestock industry. Although the livestock production and tanning industry of the world are increasing in number, the source of the material for the tanning industry is limited both in quantity and quality.2 Ethiopia produce about 2.7millions of hides, 8.1millions of sheep skin and 7.5millions of goats skin per annum and is the leading export time of the country next to coffee with its finished and semi finished leather products.3 Although the number of tannery involved in production of this products increasing from time to time, the sectors and the country are losing revenue due to decline in leather quality and fall in export price.4 Of the total skin processed of tanneries, one fourth to one third of it is unsuitable to export due to various defects, 65%, which occur in pre‒slaughter, stage.5 The existence of various skin diseases (Dermotophillosis, Demodicosis, Sarcoptes and psoroptes manges, ticks and lice infestations affecting cattle, sheep and goats are frequently reported from different parts of Ethiopia.6 These different diseases in Ethiopia are documentable for considerable economic losses culling and occasional mortalities and related with cost of treatment and prevention disease.7 The potential economic losses necessitate the nationwide investigation on the distribution of skin disease and organize efforts between farmers, trader, tanners and government to at least minimize these enormous loses. Hence in socio‒economically important city like Kutaber words so far limited studies has been made to investigate the overall prevalence of the skin diseases in domestic ruminants. Therefore, the objectives of these studies are:","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"161 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86428312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The long‒term complications of hyperglycemia in both type1 and type 2 diabetic patients","authors":"D. K. Aristarkus","doi":"10.15406/mojpb.2018.07.00244","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00244","url":null,"abstract":"","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76675255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on factors causing parkinson’s syndrome","authors":"Shanmughavel Piramanayagam, Suganya Selvaraj","doi":"10.15406/mojpb.2018.07.00243","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00243","url":null,"abstract":"Parkinson’s disease (PD) was medically reported as a neurological syndrome by James Parkinson, who first explained it in “An Essay on the Shaking Palsy” in 1817.1 He illustrated this disease as started with slow, progressive involuntary tremors, followed by a complication in walking, speech, and swallowing.2 Other than motor symptoms, Parkinson’s disease patients gradually experience remarkable non‒ motor symptoms as well as cognition decline, sensory abnormalities, behavioral changes, fatigue, sleep disturbances, and other autonomic dysfunctions.3‒5 After Alzheimer’s disease (AD), PD is the most common age‒ related neurodegenerative disease. Although the central pathological feature of Parkinson’s disease (PD) was found to be the degradation of neurons in the substantia nigra pars compacta (SNpc), (Figure 1) the loss of SNpc neurons accelerate striatal dopamine (DA) deficiency.6 Which is accountable for the key motor and nonmotor symptoms of PD.4,5 PD tremor decreases the voluntary movement, so naturally, impair the daily life activities. Rigidity refers to the increased resistance (stiffness) to passive movement of a patient’s limbs. Bradykinesia (very slow body movements) could considerably worsen the standared of life as a result of it takes for much longer to perform daily tasks like consumption of food or dressing, hypokinesia (reduction in movement amplitude), and akinesia (absence of normal oblivious movements, like arm swing in walking) evident as a range of symptoms, such as decreased voice volume (hypophonia), paucity of pronormal facial expression (hypomimia), drooling (inability to swallow without pondering it), diminished stride length during walking and slow writing. In addition, PD patients continuously enhance stooped attitude and will lose ordinary postural impulses, resulting in falls and, sometimes, confinement to a wheelchair. Abnormalities and cognition also occur frequently; delayed responses to queries, and slow cognitive process (bradyphrenia).6,7 Many shreds of evidence suggest that phosphatidylinositol‒3 kinase (PI3K)/Akt (protein kinase‒B)/mammalian target of the rapamycin (mTOR) pathway (PI3K/Akt/mTOR) pathway signaling related to dopaminergic neuron degeneration in PD.46‒48 The neuron degeneration concurrently influences the wider region of the brain responsible for dementia. In PD, dementia is not a presenting feature; it develops at least four years after PD motor symptoms start. Among PD patients, who do not primarily experience dementia the yearly occurrence varies from 2.6% to 9.6%, the additive risk of dementia by the age of 85 years was over 65%.8 Dopamine deficiency in the brain is the known causing factor of PD, yet why this initially occurs is less clear. However, the better understanding of the pathology of Parkinson’s disease is helping to identify potential drug targets for disease management.","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84480817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a label‒free nanolc/ms/ms assay for monitoring the changes in the proteomic landscape of thrombin‒activated human platelets","authors":"Cristina C. Clement, J. González, A. Babińska, Ebenezer L.V. Ewul, Edem Timpo, M. Salifu, D. Monika","doi":"10.15406/MOJPB.2018.07.00242","DOIUrl":"https://doi.org/10.15406/MOJPB.2018.07.00242","url":null,"abstract":"Platelets are small anucleated blood particles derived from megakaryocytes in the bone marrow, and they play a key role in the control of bleeding and hemostasis.1‒10 Platelets need to be activated to perform their functions, a process mediated by many physiological activators. The best known and characterized activators at the level of signaling transduction mechanisms are: thrombin, arachidonic acid and its derivatives (thromboxane A2), collagen, and the adenosine nucleotides (ADP and ATP).2‒8 Activated platelets undergo vast cytoskeleton, organelles, and secretory protein reorganization accompanied by many posttranslational modifications (PTM).5‒14 Due to their anucleate nature, platelets have limited protein synthesis, and therefore it is expected that most of the changes encountered at the level of the proteome under different pathophysiological conditions will be determined mostly by changes in protein expression (translational and post‒translational regulated), at the level of PTM, proteolysis, or secretion during platelets degranulation processes associated with their activation.11‒15 It is well documented that selected platelet messages are translated into proteins after activation, regulating the inflammatory and hemostatic responses of the platelet.2‒8 Platelets can be affected by many physiological conditions during blood circulation that can ultimately lead to vascular complications initiated by thrombus formation.12‒16 During activation, release of platelet microparticles can generate various pathophysiological effects, such as initiation and exacerbation of stroke.16,17 One of the most advanced studies applied to the research of platelets biology under different activation states is the mass spectrometry coupled with profiling of protein changes applied to both resting and activated whole platelet proteomes, or to platelet subproteomes, including the platelet granules (alpha and dense), membrane systems, lipid rafts, and enriched phosphoproteome. Research conducted in the last five years acknowledges the identification of 5000‒5500 expressed proteins in human platelets, a proteome that is highly similar between different healthy individuals.10‒21 Recent emerging analytical technologies coupling the fractionation of the cellular proteome with the multidimensional nano LC/ESI/MS/MS sequencing, together with systems biology approaches empowered by bioinformatics analysis and data mining enabled a revolution in platelet proteomics that led to the development of new, mass spectrometric‒based assays for","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77641325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing telemedicine through video conferencing","authors":"D. K. Aristarkus, S. Palaniappan","doi":"10.15406/MOJPB.2018.07.00241","DOIUrl":"https://doi.org/10.15406/MOJPB.2018.07.00241","url":null,"abstract":"When a number of users become far higher than the available bandwidth in a network, transmission delay in traffic delivery becomes unavoidable.2 These constitutes part of the technical factors that affects the reliability of internet service. However, reliable bandwidth subscription would enhance the performance of the network for impressive service delivery. Use of quality devices on the network is also a network performance milestone.3 Diagnosing a network that provides a week internet service would help in discovering loop holes and proffering a means of improving the network services.4 Characterizing a campus environment for proper view of what could serve as bottleneck or free connectivity would enhance the process of network diagnoses towards minimising any possible problems.5","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"138 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79087627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 19th century origins of the dormant stage in cancer metastasis","authors":"W. Onuigbo","doi":"10.15406/mojpb.2018.07.00240","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00240","url":null,"abstract":"","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78118812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of system for research in health with computation in cloud using artificial intelligence","authors":"Carlos Henrique Kuretzki, J. S. Pinto, José Claudio Vianna","doi":"10.15406/mojpb.2018.07.00239","DOIUrl":"https://doi.org/10.15406/mojpb.2018.07.00239","url":null,"abstract":"The health sector is one of the largest in most countries and can significantly benefit from high‒quality, real‒time and location‒ independent data. However, many healthcare professionals are not familiar with information technology solutions, business and information or are reluctant to apply them in their work area. The term Medical Informatics originated in the 1970s, inspired by the French word for Computer Science (informatique) thus passing the English‒speaking community to adopt the Medical Informatics form; previously the term related to biomedical research was vaguely defined. During the 1980s in Europe this term became broader than Medical Computing, including subjects such as Medical Statistics, Record Keeping, as well as others related to Medical Informatics itself. Over the years the word “medical” applied to this terminology gave a restrictive connotation of application to the medical field, thus, being replaced by the word health, leading to Health Informatics.1 Nowadays there are many areas that make use of technologies based on Health Informatics. Solutions that can give equal or better results than those provided by professionals. These solutions are called specialized systems. The main purpose of these systems is to find a solution to problems that are usually solved by specialized professionals in the field, and therefore the system is able to decide on its own, only based on specific and selected knowledge. This knowledge is given by the skilled professionals and based on real cases.2 Cognitive computing systems are perceptual‒sensitive systems that react to external signals and learn to do something with excellence through data analysis. That is, they receive numerous unstructured data entries and process them in order to obtain information in response to a given question or task. Cognitive technology, as a rule, proposes to perform tasks that only humans have so far been able to do, is only supposed to do it faster and more accurately.3","PeriodicalId":18585,"journal":{"name":"MOJ proteomics & bioinformatics","volume":"172 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77307231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}