Minerva cardioangiologica最新文献

Systolic, mean and pulse pressure values in patients with acute coronary syndrome: worth keeping an eye on. 急性冠状动脉综合征患者的收缩压、平均压和脉压值:值得关注。

Minerva cardioangiologica Pub Date : 2021-01-11 DOI: 10.23736/S0026-4725.20.05434-1

R. Razzolini, G. Iannaccone

引用次数: 1

Instantaneous wave-free ratio-guided revascularization of non-culprit lesion in patients with ST-segment elevation myocardial infarction and multivessel coronary disease: design and rationale of the WAVE registry. 瞬时无波率引导st段抬高型心肌梗死和多支冠状动脉疾病患者非罪魁祸首病变血运重建术:波浪登记的设计和基本原理

Minerva cardioangiologica Pub Date : 2021-01-11 DOI: 10.23736/S0026-4725.20.05229-9

C. Musto, A. Nusca, G. Biondi‐Zoccai, F. De Felice, M. Scappaticci, M. Nazzaro, M. Viscusi, A. Ceccacci, F. Versaci

{"title":"Instantaneous wave-free ratio-guided revascularization of non-culprit lesion in patients with ST-segment elevation myocardial infarction and multivessel coronary disease: design and rationale of the WAVE registry.","authors":"C. Musto, A. Nusca, G. Biondi‐Zoccai, F. De Felice, M. Scappaticci, M. Nazzaro, M. Viscusi, A. Ceccacci, F. Versaci","doi":"10.23736/S0026-4725.20.05229-9","DOIUrl":"https://doi.org/10.23736/S0026-4725.20.05229-9","url":null,"abstract":"BACKGROUND\u0000The optimal management of patients with ST-elevation acute coronary syndromes and multivessel coronary artery disease is challenging. There is a growing body of evidence supporting invasive functional evaluation of multivessel disease with FFR or iFR has been added to the literature. In this regard, the WAVE study recently demonstrated the diagnostic accuracy of iFR functional assessment of non-culprit lesions in multivessel patients with STEMI. However, no studies have still verified the long-term clinical impact of an iFR-guided revascularization in this setting of patients.\u0000\u0000\u0000METHODS\u0000Patients undergoing primary PCI for STEMI and presenting multivessel disease will be enrolled. After the treatment of the culprit lesion, an iFR-guided functional assessment of non-culprit lesions will be done: if iFR ≤ 0.89 PCI will be performed during the index procedure or staged. Conversely, iFR> 0.89 will be direct the patient towards a conservative approach.\u0000\u0000\u0000RESULTS\u0000The study start date was May 1, 2018. The enrollement phase was completed on March 30, 2020. The primary endpoint is the occurrence of Target Lesion Failure (TLF), a composite of cardiovascular death, non-fatal myocardial infarction, and ischemia-driven revascularization of the vessel previously assessed with iFR. Secondary end points include MACE (Cardiovascular death, non-fatal MI, any revascularization).\u0000\u0000\u0000CONCLUSIONS\u0000The aim of the present study is to evaluate the long-term clinical impact of an iFR-guided revascularization of the non-culprit lesions in STEMI patients with multivessel coronary artery disease.","PeriodicalId":18565,"journal":{"name":"Minerva cardioangiologica","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75184625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Clinical features and outcomes between African American and Caucasian patients with Takotsubo Syndrome. 非裔美国人和白种人Takotsubo综合征患者的临床特征和预后。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05456-0

K. Ravindra, M. D. Del Buono, J. Chiabrando, P. Westman, E. Bressi, D. Kadariya, C. Maehara, M. Dell, Liangsuo Ma, J. van Wezenbeek, F. Moeller, L. Keyser-Marcus, L. Keen, Tamas S. Gal, A. Abbate

{"title":"Clinical features and outcomes between African American and Caucasian patients with Takotsubo Syndrome.","authors":"K. Ravindra, M. D. Del Buono, J. Chiabrando, P. Westman, E. Bressi, D. Kadariya, C. Maehara, M. Dell, Liangsuo Ma, J. van Wezenbeek, F. Moeller, L. Keyser-Marcus, L. Keen, Tamas S. Gal, A. Abbate","doi":"10.23736/S0026-4725.20.05456-0","DOIUrl":"https://doi.org/10.23736/S0026-4725.20.05456-0","url":null,"abstract":"BACKGROUND\u0000Takotsubo syndrome (TS) is an acute, reversible form of heart failure, often mimicking an acute coronary syndrome (ACS). Data regarding racial differences in TS are inconsistent. The aim is to assess clinical features associated with unfavorable in-hospital outcomes between African American (AA) and Caucasian (CAU) patients.\u0000\u0000\u0000METHODS\u0000A retrospective electronic health record query identified 44 AA patients and 110 CAU patients with a diagnosis of TS. Our primary outcome was a composite of death, stroke, and cardiogenic shock during hospitalization. Variables associated with an increased risk of the primary composite outcomes were included in a logistic regression model.\u0000\u0000\u0000RESULTS\u0000Compared to CAU patients, AA patients were a more comorbid population, and presented a higher prevalence of history of illicit drug use (27.3% vs 13.6% p=0.044). There were no significant differences regarding in-hospital complication rates between AA and CAU patients. In the logistic regression model, infection was associated with greater risk of developing the primary outcome in AA patients (OR=7.26 95% CI [1.22-43.17], p=0.029), whereas angina was a protective factor (OR=0.11 95% CI [0.02-0.65], p=0.015). In CAU patients, severely depressed ejection fraction and worse peak creatinine during hospitalization increased risk of developing the primary outcome (OR=5.88 95% CI [2.01-17.17], p<0.001 and OR=1.64 95% CI [1.15-2.58], p=0.031, respectively). Meanwhile, emotional stressors were protective (OR=0.16 95% CI [0.03-0.88], p=0.004).\u0000\u0000\u0000CONCLUSIONS\u0000Despite experiencing the same rate of in-hospital complications, the clinical profiles of AA patients are distinct from CAU patients admitted for TS, and clinical variables correlated with worse in-hospital outcomes also differ by race.","PeriodicalId":18565,"journal":{"name":"Minerva cardioangiologica","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76013512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Racial differences in Takotsubo Cardiomyopathy: more alike than different? Takotsubo心肌病的种族差异:相似多于不同?

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05571-1

E. Michos, P. Sabouret

引用次数: 0

Stent Oversizing or not-oversizing? An unresolved dilemma. 支架尺寸过大还是不过大?一个悬而未决的困境。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05570-X

Simone Calcagno, V. Sucato, F. Versaci

引用次数: 1

Cannabis, health and prevention. 大麻、健康和预防。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05602-9

G. Testino, P. Balbinot, R. Pellicano

引用次数: 0

The role of chronic obstructive pulmonary disease in acute coronary syndrome patients: a critical risk factor for lipid plaque burden? 慢性阻塞性肺疾病在急性冠状动脉综合征患者中的作用:脂质斑块负担的关键危险因素?

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05555-3

F. Piroli, A. Leone, Simone Calcagno

引用次数: 0

Left ventricular global longitudinal strain assessment in patients with Takotsubo Cardiomyopathy: a call for an echocardiography-based classification. Takotsubo心肌病患者左心室整体纵向应变评估:超声心动图分类的呼吁。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05386-4

Gemma Reddin, Brian J. Forrestal, H. Garcia-Garcia, D. Medvedofsky, Manavotam Singh, F. Asch, H. Ribeiro, C. Campos

{"title":"Left ventricular global longitudinal strain assessment in patients with Takotsubo Cardiomyopathy: a call for an echocardiography-based classification.","authors":"Gemma Reddin, Brian J. Forrestal, H. Garcia-Garcia, D. Medvedofsky, Manavotam Singh, F. Asch, H. Ribeiro, C. Campos","doi":"10.23736/S0026-4725.20.05386-4","DOIUrl":"https://doi.org/10.23736/S0026-4725.20.05386-4","url":null,"abstract":"BACKGROUND\u0000Takotsubo Cardiomyopathy (TTC) is classified into 4 types dependent on anatomical area affected identified on gross visual assessment. We have sought to understand if it is feasible and advantageous to use left ventricular global longitudinal strain (LVGLS), LV segmental longitudinal strain and right ventricle free wall strain (RVFWS) to classify TTC.\u0000\u0000\u0000METHODS\u0000We conducted a retrospective observational study on twenty-five patients who meet the Modified Mayo Clinic Criteria for TTC [1]. Two independent reviewers performed strain analysis, they were both blinded to patient's diagnosed classification and outcomes.\u0000\u0000\u0000RESULTS\u0000Based on classification by traditional assessment the 92% (n=23) were diagnosed with typical TTC, indicating apical involvement. The entire LV was affected, 67% (n=16) had abnormal strain (STE>-18) in all three LV regions (base, mid ventricle and apex). 71% of patients (n=17) had abnormal LVGLS (>-18). Abnormal strain across all three LV regions was associated with higher prevalence (70%, n=8 Vs 30%, n=4 respectively) of composite cardiovascular events and longer length of hospital stay. There was a statistically significant difference in average length of hospital stay in those patients who had abnormal strain in all three region compared to those that did not have abnormal strain across all three regions (8 days compared to 3.44 days, p value 0.02).\u0000\u0000\u0000CONCLUSIONS\u0000A new classification of TCC based on strain analysis should be developed. The traditional model is arbitrary; it fails to recognize that in most patients the entire LV is affect, it does not have prognostic significance and the most prevalent typical variant indicates apical involvement. Our study suggests that the entire LV is affected, and strain analysis has prognostic significance.","PeriodicalId":18565,"journal":{"name":"Minerva cardioangiologica","volume":"428 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75906940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Diabetic cardiomyopathy and inflammation: development of hostile microenvironment resulting in cardiac damage. 糖尿病性心肌病和炎症:不良微环境的发展导致心脏损伤。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05454-7

E. Elia, S. Ministrini, F. Carbone, F. Montecucco

{"title":"Diabetic cardiomyopathy and inflammation: development of hostile microenvironment resulting in cardiac damage.","authors":"E. Elia, S. Ministrini, F. Carbone, F. Montecucco","doi":"10.23736/S0026-4725.20.05454-7","DOIUrl":"https://doi.org/10.23736/S0026-4725.20.05454-7","url":null,"abstract":"Diabetes mellitus is emerging as a major risk factor for heart failure. Diabetic cardiomyopathy is defined as a myocardial dysfunction that is not caused by underlying hypertension or coronary artery disease. Studies about clinical features, natural history and outcomes of the disease are few and often conflicting, because a universally accepted operative definition of diabetic cardiomyopathy is still lacking. Hyperglycemia and related metabolic and endocrine disorders are the triggering factors of myocardial damage in diabetic cardiomyopathy through multiple mechanisms. Among these mechanisms, inflammation has a relevant role, similar to other chronic myocardial disease, such as hypertensive or ischemic heart disease. A balance between inflammatory damage and healing processes is fundamental for homeostasis of myocardial tissue, whereas diabetes mellitus produces an imbalance, promoting inflammation and delaying healing. Therefore, diabetes-related chronic inflammatory state can produce a progressive qualitative deterioration of myocardial tissue, which reflects on progressive left ventricular functional impairment, which can be either diastolic, with prevalent myocardial hypertrophy, or systolic, with prevalent myocardial fibrosis. The aim of this narrative review is to summarize the existing evidence about the role of inflammation in diabetic cardiomyopathy onset and development. Ultimately, potential pharmacological strategies targeting inflammatory response will be reviewed and discussed.","PeriodicalId":18565,"journal":{"name":"Minerva cardioangiologica","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90432651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Exercise and adverse ventricular remodeling. The cornerstone of heart failure. 运动和不良心室重构。心脏衰竭的基础。

Minerva cardioangiologica Pub Date : 2021-01-01 DOI: 10.23736/S0026-4725.20.05442-0

J. Chiabrando, M. Feola

引用次数: 0