Materials Today Communications最新文献

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Corrosion-microenvironment-responsive etidronate-loaded alkali lignin nanoparticle/silane coating for degradation regulation of ZE21C magnesium alloy 腐蚀-微环境响应的依地膦酸负载碱木质素纳米颗粒/硅烷涂层对ZE21C镁合金的降解调控
3区 材料科学
Materials Today Communications Pub Date : 2026-07-01 DOI: 10.1016/j.mtcomm.2026.115932
Wenjiang Huang, Xiaoao Li, Ruiyang Yao, Jianjiang Xin, Jiali Zhang, Yongzheng He
{"title":"Corrosion-microenvironment-responsive etidronate-loaded alkali lignin nanoparticle/silane coating for degradation regulation of ZE21C magnesium alloy","authors":"Wenjiang Huang, Xiaoao Li, Ruiyang Yao, Jianjiang Xin, Jiali Zhang, Yongzheng He","doi":"10.1016/j.mtcomm.2026.115932","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.115932","url":null,"abstract":"","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"55 1","pages":"115932-115932"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148861181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-response behavior of chitosan humidity sensors via tailored electrode structures 定制电极结构壳聚糖湿度传感器的双响应特性
3区 材料科学
Materials Today Communications Pub Date : 2026-04-01 DOI: 10.1016/j.mtcomm.2026.115285
Huangping Yan, Zhijun Ye, Yuyang Wang, Anna He, Jingqin Cui, Rui Zhou, Gaofeng Zheng
{"title":"Dual-response behavior of chitosan humidity sensors via tailored electrode structures","authors":"Huangping Yan, Zhijun Ye, Yuyang Wang, Anna He, Jingqin Cui, Rui Zhou, Gaofeng Zheng","doi":"10.1016/j.mtcomm.2026.115285","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.115285","url":null,"abstract":"Accurate humidity measurement is critical in environmental monitoring, industrial process control, medical diagnostics, and related fields. The use of humidity-sensitive materials exhibiting dual capacitance/resistance response characteristics offers a promising strategy to enhance sensor applicability. In this study, a chitosan humidity sensor was developed to systematically investigate its dual-response behavior under varying humidity conditions (6%–92%RH). Sensors with different interdigitated electrode configurations were fabricated and characterized at 1 kHz to evaluate their humidity sensing performance. Experimental results demonstrate outstanding sensor performance, including high response (5382.29% in capacitance and 99.99% in resistance) and rapid response/recovery times (within 10 s and 30 s, respectively). Among the configurations tested, the interdigitated electrodes design exhibits the most pronounced capacitance response, accompanied by a notable resistance response and the fastest response/recovery times, establishing it as the optimal electrode structure. The dual-response mechanism was elucidated using a water adsorption model, revealing distinct capacitance and resistance behaviors, while different electrode configurations modulate ion transport pathways and electric field distribution, accounting for the observed performance differences. Non-contact sensing tests further validate the practical potential of the dual-response characteristics. These findings provide valuable insights for optimizing the design and expanding the applicability of advanced humidity sensors.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"53 1","pages":"115285-115285"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined regulation of ammonium polyphosphate-coated hollow glass microspheres and SmMn2O5 mullite: Balancing flame retardancy, lightweight, and pressure resistance of epoxy composites 聚磷酸铵包覆中空玻璃微球和SmMn2O5莫来石的复合调控:平衡环氧复合材料的阻燃、轻质和耐压性能
3区 材料科学
Materials Today Communications Pub Date : 2026-03-01 DOI: 10.1016/j.mtcomm.2026.115048
Xingcan Lu, Tao Li, Zijian Feng, Xuan Wang, Ze Chen, Chaojun Yang, S Chen, S. Liu, Yu Li
{"title":"Combined regulation of ammonium polyphosphate-coated hollow glass microspheres and SmMn2O5 mullite: Balancing flame retardancy, lightweight, and pressure resistance of epoxy composites","authors":"Xingcan Lu, Tao Li, Zijian Feng, Xuan Wang, Ze Chen, Chaojun Yang, S Chen, S. Liu, Yu Li","doi":"10.1016/j.mtcomm.2026.115048","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.115048","url":null,"abstract":"Epoxy resin-hollow glass microsphere composites (EHC) exhibit low density and excellent mechanical properties, making them promising candidates for marine/aerospace applications. However, their high flammability severely restricts broader use. To improve flame retardancy while maintaining low density, ammonium polyphosphate-coated hollow glass microspheres (APP-HGM) were utilized to fabricate flame-retardant epoxy composites (EAHC). EAHC achieved improved flame retardancy and maintained low density, but it suffered from insufficient flame-retardant efficiency and notable mechanical degradation. To address these drawbacks, SmMn 2 O 5 mullite nanoparticles (SMO) were further incorporated to fabricate the multi-component flame-retardant epoxy composite (SMO-EAHC). Systematic characterizations including thermogravimetric analysis (TG), limiting oxygen index (LOI), vertical burning (UL-94) and cone calorimeter test confirmed that APP-HGM serves as both a flame-retardant filler and a lightweight matrix component, while SMO catalyzes the decomposition of APP and promotes the formation of compact char layers. SMO-EAHC achieved a LOI of 27.6% and a UL-94 V-1 rating, and presented remarkable reductions of 58.81%, 38.67%, 73.65% and 62.96% in peak heat release rate (pHRR), total heat release (THR), peak smoke production rate (pSPR) and total smoke production (TSP) compared with unmodified EHC. Meanwhile, SMO-EAHC exhibited a compressive strength of 23.84 MPa, representing a 32.08% improvement relative to EAHC, while maintaining a low density of 0.66 g/cm³. In summary, this work proposes a targeted two-step modification strategy, involving APP-HGM functionalization followed by SMO complementation, to address the flammability of EHC. This strategy realizes the balanced integration of flame retardancy, lightweight characteristic and pressure resistance, providing technical support for the application of polymer composites in extreme environments. • Prepare SMO-EAHC by integrating APP-HGM and SmMn₂O₅ into modified epoxy. • SMO catalyzes APP decomposition, consolidates char layer. • SMO-EAHC attains LOI 27.6% (UL-94 V-1), 58.81% pHRR & 73.65% pSPR cuts vs EHC. • Retains low density (0.66 g/cm³) and high pressure resistance (23.84 MPa). • Offers technical support for flame-retardant composites in marine/aerospace.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"52 1","pages":"115048-115048"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct growth of TiO2 nanotubes with well-morphology and high {001} facets exposure ratio by H3PO4/HF-assisted anodic oxidation H3PO4/ hf辅助阳极氧化直接生长形貌良好、高{001}面曝光率的TiO2纳米管
3区 材料科学
Materials Today Communications Pub Date : 2026-01-19 DOI: 10.1016/j.mtcomm.2026.114703
Wei Gan, Can Jiang, Yao Wang, Min Ling, Shengfu Zhang
{"title":"Direct growth of TiO2 nanotubes with well-morphology and high {001} facets exposure ratio by H3PO4/HF-assisted anodic oxidation","authors":"Wei Gan, Can Jiang, Yao Wang, Min Ling, Shengfu Zhang","doi":"10.1016/j.mtcomm.2026.114703","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.114703","url":null,"abstract":"It is challenging to develop well-designed photocatalysts with high activity. In this work, TiO 2 nanotubes (TiO 2 -NTs,TNT) with well-morphology and high {001} facets exposure ratio were directly synthesized by H 3 PO 4 /HF-assisted two-step anodic oxidation. The results show that the addition of 3 wt% H 3 PO 4 and 0.5 wt% HF into the electrolyte facilitates the preparation of TiO 2 -NTs with an average crack density of 0 % and {001} facets exposure ratios up to 80.00 %. Moreover, the PO 4 3- and HPO 4 2- in the anode effectively hinder the generation of electron current and release of oxygen bubbles on the surface of Ti substrate, which reduces the surface cracks of TiO 2 -NTs. The F - in the electrolyte is adsorbed on the {001} facets of the TiO 2 -NTs, which decreases the energy of the O-Ti-O, thus achieving the purpose of high {001} facets exposure ratio. Ultimately, the excellent optical properties, in conjunction with the synergistic effect of {001} facets-selective orientation and O V , significantly enhanced the photocatalytic activity of TiO 2 -NTs, resulting in the removal of 90.32 % Rhodamine B in 120 min under visible light illumination. This work could shed light on the new approach to the rational design of high-efficiency TiO 2 -NTs-based photocatalysts. • Well-morphology TiO2-NTs with high {001} facets exposure ratio were directly prepared. • PO43- is the main reason for reducing electron current generation and oxygen release. • Beneficial oxygen vacancies (OV) were constructed on TiO2-NTs by F-. • Degradation efficiency of RhB by the optimized TiO2-NTs up to 90.32 % within 120 min.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"51 1","pages":"114703-114703"},"PeriodicalIF":0.0,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and compositional synergy in (CCWs/rGOAs):PANI composites for high-efficiency microwave absorption 高效微波吸收的聚苯胺(CCWs/rGOAs)复合材料的结构和成分协同作用
3区 材料科学
Materials Today Communications Pub Date : 2026-01-18 DOI: 10.1016/j.mtcomm.2026.114686
Kun Wang, Dongdong Deng, Yuxiang Nie, Chao Liu, Hongxiao Yu, Tongxu Cui, Bin Yao, Bingqi Xia
{"title":"Structural and compositional synergy in (CCWs/rGOAs):PANI composites for high-efficiency microwave absorption","authors":"Kun Wang, Dongdong Deng, Yuxiang Nie, Chao Liu, Hongxiao Yu, Tongxu Cui, Bin Yao, Bingqi Xia","doi":"10.1016/j.mtcomm.2026.114686","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.114686","url":null,"abstract":"Biomass-derived carbonized cicada wings (CCWs) exhibit unique microstructures and demonstrate promise as lightweight microwave-absorbing materials. However, their practical application is hindered by inherently inadequate dielectric loss capabilities and poor impedance matching. To address this limitation, ternary CCWs/Reduced graphene oxide aerogels (rGOAs)/polyaniline (PANI) composites were fabricated through mechanical grinding of CCWs with rGOAs and PANI particles. The synergistic integration of rGOAs and PANI significantly enhanced the dielectric loss capacity and optimized impedance matching behavior, substantially improving electromagnetic wave attenuation performance. The minimum reflection loss ( RL min ) of −61.36 dB at 1.8 mm, and an effective absorption bandwidth ( RL ≤ −10 dB) of 5.2 GHz (12.8–18 GHz). This study reveals the significant potential of (CCWs/rGOAs):PANI composites as promising candidates for lightweight, high-performance microwave-absorbing materials.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"51 1","pages":"114686-114686"},"PeriodicalIF":0.0,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147899478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermophysical and mechanical modulation of RE3NbO7 ceramics via compositional entropy design 基于成分熵设计的RE3NbO7陶瓷的热物理和力学调制
3区 材料科学
Materials Today Communications Pub Date : 2026-01-18 DOI: 10.1016/j.mtcomm.2026.114688
Shenglan Xiang, Yuhang Wu, Dierui Hu, M. Zhang, Wei Wen
{"title":"Thermophysical and mechanical modulation of RE3NbO7 ceramics via compositional entropy design","authors":"Shenglan Xiang, Yuhang Wu, Dierui Hu, M. Zhang, Wei Wen","doi":"10.1016/j.mtcomm.2026.114688","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.114688","url":null,"abstract":"High-entropy ceramics, renowned for their exceptional thermal insulation and stability, hold significant potential for thermal barrier coating applications in extreme environments. In this study, two rare-earth niobate ceramics—(Sc 1/4 Ho 1/4 Er 1/4 Yb 1/4 ) 3 NbO 7 (SHEY) and (Sc 1/5 Gd 1/5 Ho 1/5 Er 1/5 Yb 1/5 ) 3 NbO 7 (SGHEY)—were synthesized via solid-state reaction. The influence of rare-earth element composition on the thermal and mechanical properties was systematically investigated. SHEY and SGHEY exhibit nearly identical thermal expansion coefficients (TEC), with TECs at 1200 °C of 10.57 × 10 -6 K -1 and 10.52 × 10 -6 K -1 , respectively, indicating good thermal expansion matching with typical substrate and bond-coat materials in thermal barrier coating systems. Compared with SHEY, SGHEY possesses a finer grain size (3.17 μm vs. 4.70 μm), lower thermal conductivity at 1200 °C (1.38 vs. 1.76 W·m -1 ·K -1 ), and slightly higher fracture toughness (1.34 vs. 1.31 MPa·m 1/2 ), suggesting that incorporating Sc and Gd improves the balance between thermal insulation and mechanical robustness in the high-entropy niobate system.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"51 1","pages":"114688-114688"},"PeriodicalIF":0.0,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147921184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioengineered silk fibroin/chitosan nanofibrous scaffolds: A biomimetic platform for advanced skin tissue regeneration and repair 生物工程丝素/壳聚糖纳米纤维支架:用于高级皮肤组织再生和修复的仿生平台
3区 材料科学
Materials Today Communications Pub Date : 2026-01-01 DOI: 10.1016/j.mtcomm.2026.114623
Shu-Dong Wang, Ke Wang, Jin Yan, Chen Ding, Youzhu Zhang
{"title":"Bioengineered silk fibroin/chitosan nanofibrous scaffolds: A biomimetic platform for advanced skin tissue regeneration and repair","authors":"Shu-Dong Wang, Ke Wang, Jin Yan, Chen Ding, Youzhu Zhang","doi":"10.1016/j.mtcomm.2026.114623","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2026.114623","url":null,"abstract":"","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"50 1","pages":"114623-114623"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147915378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multifunctional polyacrylamide-based interfacial evaporator with enhanced photothermal conversion and biofouling resistance for efficient solar desalination 一种基于聚丙烯酰胺的多功能界面蒸发器,具有增强的光热转换和抗生物污染能力,用于高效太阳能海水淡化
3区 材料科学
Materials Today Communications Pub Date : 2025-12-29 DOI: 10.1016/j.mtcomm.2025.114588
Tuanzhang Li, Xiaolei Li, Zuning Luo, Jiehua Li, Shujie Chang, Hu Zhang, SIDONG LI, Chuanming Yu, L X Li
{"title":"A multifunctional polyacrylamide-based interfacial evaporator with enhanced photothermal conversion and biofouling resistance for efficient solar desalination","authors":"Tuanzhang Li, Xiaolei Li, Zuning Luo, Jiehua Li, Shujie Chang, Hu Zhang, SIDONG LI, Chuanming Yu, L X Li","doi":"10.1016/j.mtcomm.2025.114588","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2025.114588","url":null,"abstract":"Solar-driven interfacial evaporation (ISE) has been identified as a potentially viable solution to the global water scarcity problem, with the capability of enabling energy-efficient desalination under ambient conditions. However, current ISE systems frequently exhibit signs of performance degradation, often attributable to salt accumulation and microbial contamination during extended operation. In this study, we present a multifunctional polyacrylamide-based interfacial evaporator (CAP) that integrates in situ synthesized carbon nanotubes/silver nanoparticles (CNTs/AgNPs) composites. The AgNPs exhibit robust antibacterial activity, while the CNTs contribute to broadband photothermal absorption. The hydrogel matrix features tunable crosslinking density, which is optimised to facilitate water mobility and reduce the evaporation enthalpy. In conditions of illumination from a single sun, the CAP demonstrates a high evaporation rate of 2.3 kg·m -2 ·h -1 , exhibiting exceptional resistance to biofouling and salt crystallisation. Furthermore, the CAP produces freshwater with ion concentrations below 1 ppm, meeting WHO drinking standards. This work provides a scalable strategy to overcome the dual challenges of biofouling and salinity, paving the way for next-generation sustainable desalination technologies.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"50 1","pages":"114588-114588"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectorite/polyimide films with superior atomic oxygen resistance by a dual-protection strategy 累托石/聚酰亚胺薄膜通过双重保护策略具有优异的抗氧原子性
3区 材料科学
Materials Today Communications Pub Date : 2025-12-29 DOI: 10.1016/j.mtcomm.2025.114587
Ruiheng Feng, Qiang Wei, Chuanjin Huang, Libin Zhao
{"title":"Rectorite/polyimide films with superior atomic oxygen resistance by a dual-protection strategy","authors":"Ruiheng Feng, Qiang Wei, Chuanjin Huang, Libin Zhao","doi":"10.1016/j.mtcomm.2025.114587","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2025.114587","url":null,"abstract":"Polyimide (PI) has become an indispensable key material for low-Earth orbit (LEO) spacecraft due to its excellent performance. However, it is highly susceptible to atomic oxygen (AO) erosion, which severely limits the service lifetime of spacecraft. Herein, a dual-protection (matrix modification and coating) strategy is proposed to improve the anti-AO capacity of PI by introducing rectorite nanosheets (RNs) with outstanding AO resistance. The dual-protected rectorite/PI film shows lower AO erosion yield (only 4.04% of the pristine PI film) and more stable mechanical properties after AO irradiation. The AO-resistant mechanism is attributed to the blocking and adsorbing AO of RNs based on the experiment investigation and molecular dynamic simulation. The key advantage of this method is that, even if the coating is compromised, the RNs embedded in the matrix can still provide resistance against AO erosion. Consequently, this protection strategy provides a new approach for constructing superior AO-resistant PI films applicable in LEO conditions. • Rectorite nanosheets are simply and quickly fabricated by ball milling • Dual-protected rectorite/polyimide films show exceptional atomic oxygen resistance • The advantages of the dual-protection strategy are thoroughly explored • The blocking and adsorbing mechanisms of rectorite nanosheets are deeply revealed","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"50 1","pages":"114587-114587"},"PeriodicalIF":0.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147331874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curcumin encapsulated PLGA-chitosan nanocarrier: Fabrication, characterization, and in vitro differentiation evaluation on PC12 cells 姜黄素包封plga -壳聚糖纳米载体的制备、表征及对PC12细胞的体外分化评价
3区 材料科学
Materials Today Communications Pub Date : 2025-12-23 DOI: 10.1016/j.mtcomm.2025.114549
Renzhang Liang, Cuilian Yu, Dong Ma, Xiaohan Cao, Liying Bai, Yulan Li, Jingxian Zhang, Jiayue Liu, Xia Qiao, Bingren Tian
{"title":"Curcumin encapsulated PLGA-chitosan nanocarrier: Fabrication, characterization, and in vitro differentiation evaluation on PC12 cells","authors":"Renzhang Liang, Cuilian Yu, Dong Ma, Xiaohan Cao, Liying Bai, Yulan Li, Jingxian Zhang, Jiayue Liu, Xia Qiao, Bingren Tian","doi":"10.1016/j.mtcomm.2025.114549","DOIUrl":"https://doi.org/10.1016/j.mtcomm.2025.114549","url":null,"abstract":"Curcumin, a polyphenolic compound, demonstrates neuroprotective potential through its antioxidant, anti-inflammatory, and anti-amyloid activities. To enhance its delivery, we fabricated poly(lactic-co-glycolic acid) (PLGA) nanoparticles encapsulating curcumin and stabilized them with chitosan. Successful formulation was confirmed by FTIR, XRD, and SEM analyses. Zeta potential measurement confirmed a surface charge reversal from -28.1 mV (uncoated PLGA) to + 14.7 mV after chitosan coating. The nanoparticles exhibited favorable drug loading (4.09 ± 0.02 % to 5.67 ± 0.01 %) and encapsulation efficiency (14.33 ± 0.08 % to 19.85 ± 0.04 %), and provided a sustained release profile (>24 h) enhanced by chitosan. The curcumin encapsulated PLGA-chitosan nanocarriers demonstrated potent antioxidant activity (>80 % DPPH scavenging at 0.75 mg/mL) and no significant cytotoxicity against PC12 cells at concentrations up to 80 μg/mL. In HCT116 cells, the chitosan coating enhanced cellular uptake and cytoplasmic distribution. Crucially, the nanocarriers promoted PC12 cells differentiation, resulting in a high proportion of neurite-bearing cells. These findings indicate that the designed chitosan-coated PLGA nanoparticles are a promising delivery system for promoting neuronal differentiation.","PeriodicalId":18477,"journal":{"name":"Materials Today Communications","volume":"50 1","pages":"114549-114549"},"PeriodicalIF":0.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147331533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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