Sumatera Medical Journal最新文献

{"title":"ASSOCIATION BETWEEN SERUM ALP LEVELS AND PRE-OPERATIVE LDH TOWARDS CLINICAL PROGNOSIS OF OSTEOSARCOMA PATIENTS IN H. ADAM MALIK HOSPITAL, MEDAN","authors":"Gerhard Christoffel Tampubolon, Otman Siregar, Andriandi","doi":"10.32734/sumej.v6i1.8991","DOIUrl":"https://doi.org/10.32734/sumej.v6i1.8991","url":null,"abstract":"Background: The prognosis of osteosarcoma is very unsatisfactory due to frequent tumor metastases to the lung or resistance to chemotherapy. A marker is needed to identify the prognosis of patients with osteosarcoma when diagnosed with the aim of being able to receive cancer treatment as soon as possible to improve a better prognosis. Alkaline phosphatase (ALP) and Lactate dehydrogenase (LDH) have potential in assessing the prognosis in osteosarcoma. \u0000Purpose and Objectives: The researcher wanted to investigate the relationship between preoperative serum ALP and LDH levels on the clinical prognosis of osteosarcoma patients. \u0000Methods: This research is analytic retrospective with the source of data is medical records and was conducted at the Department of Surgery FK-USU/RSUP Haji Adam Malik Medan with research code of ethics No. 426/KEPK/USU/2022. The subjects of this study were patients with osteosarcoma who were treated at Division of Orthopedic Surgery at Haji Adam Malik Hospital Medan from January 2015-December 2017 who met the inclusion criteria. \u0000Results: There was no significant relationship between ALP and LDH with five-year survival with p-values ​​of 0.557 and 0.179 (p>0.05). ALP has a weak correlation with five-year survival with an r value of -0.019 which means the higher the ALP, the lower the five-year survival of the patient. Meanwhile, LDH has a weak correlation with an r value of 0.093, which means the higher the LDH, the higher the patient's five-year survival. The ALP value in this study had a median value of 212 U/L and an LDH value of 489 U/L. ALP has sensitivity of 61.1% and specificity of 57.1% with a cut-off of 217.5 U/L. Meanwhile, LDH sensitivity was 61.2% and specificity was 51.4% with a cut-off of 488.5 U/L. \u0000Conclusion: There is no significant relationship between ALP and LDH with five-year survival.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115494260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors Associated with Maskne in the Era of the COVID-19 Pandemic","authors":"S. Az-Zahra, N. K. Jusuf","doi":"10.32734/sumej.v6i1.8015","DOIUrl":"https://doi.org/10.32734/sumej.v6i1.8015","url":null,"abstract":"The necessity to always use a mask in the era of the COVID-19 pandemic has given rise to a new term called maskne. Maskne is the appearance of acne that is triggered by wearing a mask. It usually occurs specifically in the area covered by the mask, focused on the cheeks, chin, and nose. This study aims to determine the risk factors associated with the occurrence of maskne. A cross-sectional study was conducted on the Faculty of Medicine students, Universitas Sumatera Utara class 2018. This study uses primary data from questionnaires and observation of respondents' face photos. Based on statistical analysis, 99 out of 221 respondents (44.8%) experienced maskne. Bivariate analysis shows p-values <0.05  for gender, duration of mask use, and previous acne history. On the other hand, it was obtained p-value >0.05 for the type of mask and mask changing habit. Based on multivariate analysis, the p-value <0.05 for gender indicates that gender is the most dominant risk factor in the incidence of maskne. Furthermore, there is a significant association between gender and the occurrence of maskne. Females are twice as likely to experience maskne.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1578 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127889404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of Knowledge among Medical Student Regarding The Role of Vitamin C For Skin Health in Universitas Sumatera Utara","authors":"Hening Yumi, Wardoyo Putri, Nova Z airina Lubis","doi":"10.32734/sumej.v5i1.6514","DOIUrl":"https://doi.org/10.32734/sumej.v5i1.6514","url":null,"abstract":"BACKGROUND: The main function of vitamin C for skin health is as an antioxidant, combating environmental oxidative stress, which helps the natural regeneration of environmental oxidative stressors, collagen formation and brightening the skin. Humans cannot synthesize their own vitamin C, so to meet the vitamin C needs of the body, humans must consume vitamin C from fresh fruits and vegetables. In addition to oral and topical use, the practice of using vitamin C by injection has also been widely spread in major cities in Indonesia. Taking vitamin C is not something bad, but using vitamin C that is not according to the recommended dosage can have unwanted effects on health. \u0000OBJECTIVE: This study aims to determine the level of knowledge of students at the Faculty of Medicine, Universitas Sumatera Utara to regarding the role of vitamin C for skin health in 2020. \u0000METHODS: This study used a descriptive observational method with a cross sectional design. The sample size in this study was 247 people. The samples used were students of Faculty of Medicine at the Universitas Sumatera Utara class 2017, 2018, and 2019. Data on student knowledge levels collected from the results of filling out the questionnaire will be grouped using the Guttman scale and forwarded for further data processing using the Statistical Package for Social Sciences (SPSS) program 25 . \u0000RESULTS : In this study it was found that 86.3% of respondents had sufficient knowledge about the role of vitamin C for skin health, 91.2% of female respondents had sufficient knowledge, 81.5% of male respondents had sufficient knowledge. Based on how to use vitamin C, it can be seen that 41.9% of students have high knowledge about the use of vitamin C orally, 60% of respondents have sufficient knowledge about the use of vitamin C topically, and 50.4% of respondents have sufficient knowledge about its use vitamin C by injection. \u0000CONCLUSION: The level of knowledge of students at the Faculty of Medicine at the Universitas Sumatera Utara, for 2017, 2018 and 2019 regarding the role of vitamin C for skin health is sufficient. There are differences in the level of knowledge according to gender in this study, it was found that women have a better level of knowledge than men.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125999730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARISON OF ASSESSMENT OF ABBREVIATED BURN SEVERITY INDEX (ABSI) AND BELGIAN OUTCOME OF BURN INJURY (BOBI) AT H. ADAM MALIK GENERAL HOSPITAL","authors":"Rifwanul Basir Nasution","doi":"10.32734/sumej.v5i2.8966","DOIUrl":"https://doi.org/10.32734/sumej.v5i2.8966","url":null,"abstract":"Background: Assessment of length of stay and mortality in patients with burn injuries is essential to support clinicians in making clinical decisions. In Indonesia, there are several scoring systems used by hospital centers to assess the mortality of burn patients, such as the Belgian Outcome of Burn Injury (BOBI) and the Abbreviated Burn Severity Index (ABSI). However, different results were obtained in studies that examined the comparison of the results of the scoring system. \u0000Method: The type of research used in this research is unpaired comparative analysis research using a cross-sectional design. The data to be used is secondary data taken from medical records. \u0000Results: Respondents with death status were found in the serious, severe, and maximum ABSI categories, p=0.001 (p<0.05) and the BOBI 50% category as many as three people and 85% as many as one person, p=0.0001 (0<0.05). Length of stay based on the ABSI score for the length of stay was 23 days with an ABSI score of 12-13 (maximum), and based on the BOBI Score, the majority was 28 days with a BOBI score of 8 (85%). ABSI in this study had a sensitivity of 100% and a specificity of 86.4%, while the use of BOBI in this study had a sensitivity of 100% and a specificity of 88.1%. \u0000Discussion: The BOBI scoring system is more accurate than the ABSI. This difference may occur due to differences in demographics and quality of service in each region. Therefore, the analysis of the validity of the scoring model before the research is carried out in a new population is considered crucial to be carried out.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"11 1-2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120930474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSOCIATION OF GLYCOSYLLATED HEMOGLOBIN (HbA1C) LEVELS TO THE SEVERITY OF DIABETIC FOOT ULCER IN TYPE 2 DIABETES MELLITUS PATIENTS IN RSUP. H. ADAM MALIK MEDAN","authors":"Muhammad Imran Porkas Lubis","doi":"10.32734/sumej.v5i1.9060","DOIUrl":"https://doi.org/10.32734/sumej.v5i1.9060","url":null,"abstract":"Abstrak \u0000Introduction: Diabetic ulcers with neuropathy require amputation or time to fully heal. The worse blood sugar control, it will worsen the condition of complications such as diabetic ulcers, diabetic neuropathy, and other complications. Wound healing in diabetic ulcers is influenced by controlled HbA1c levels. \u0000Methods: This study is an observational analytic study with a retrospective design used in this study with secondary data. This study is analytical because it aims to obtain the correlation of HbA1c with the severity of diabetic ulcers in patients with diabetes mellitus at H. Adam Malik Hospital. \u0000Results: The average age of the patients was 62 with the majority of respondents being male. The dominance of respondents came with Grade IV as many as 17 people, with uncontrolled HbA1c levels as many as 39 people. Using Spearman Corelation test, the value of r = 0.735, 0.736, and 0.785, respecttively for the corelation between HbA1c, Hb and ESR levels with the severity of diabetic foot ulcers ,with a value (p = 0.0001). \u0000Conclusion: We found a strong correlation and a significant relationship between HbA1c, Hb, and ESR levels with the severity of diabetic foot ulcers.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124449921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report VP shunt in Non Communicating Hydrocephalus due to Intracerebral Hemorrhage","authors":"F. Muharam, Rully Hanafi Dahlan, Seyline Estethia Ompusunggu","doi":"10.32734/sumej.v5i1.9383","DOIUrl":"https://doi.org/10.32734/sumej.v5i1.9383","url":null,"abstract":"Stroke is one of the top three cause of death and disability globally. Approximately, only 10% to 15% of first-ever stroke are intracerebral hemorrhages (ICHs), but the rates of disability and death are significantly higher. Hydrocephalus may occur in more than 50% of patients with intraventricular hemorrhage (IVH), which is secondary to ICH.  Intraventricular hemorrhage (IVH), an accumulation of blood to ventricles that may be cause by extension of ICH, occurs in up to 50% of patients with primary ICH.  Hydrocephalus itself may serves as a predictor of poor outcome after ICH.1,2,3 \u0000A 71 years old male came to the hospital with the complaint of loss of consciousness, difficulty in communicating, and weakness of extremities on the left side of the body since 12 hours ago. The complaint was preceded by headache that did not alleviate with medication since 1 day before admission and there was history of slurred speech. A head CT scan without contrast was done and the result showed an intracerebral hemorrhage and a suggestive obstructive hydrocephalus. The patient was diagnosed noncommunicating hydrocephalus due to spontaneous intracerebral haemorrhage (ICH) at the right thalamus with intraventricular haemorrhage due to suspect hypertension with differential diagnosis of cerebral amyloid angiopathy with emergency hypertension. The patient was advised to underwent an emergency VP shunt placement. \u0000Implantation of a ventriculoperitoneal (VP) shunt is the most widely used treatment of hydrocephalus. Considered to be a major privonce of neurosurgery, it accounts for 70.000 hospital admission in the US. Even though, VP shunting of CSF reduces the morbidity and mortality of post-hemorrhagic. hydrocephalus, it is associated with potential complications requiring multiple surgical procedures, as well as shunt revision due to its failure during the patient’s lifetime.4","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124138638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RISK FACTOR ANALYSIS OF LOW BACK PAIN IN EMPLOYEES OF DRINKING WATER STORE IN MEDAN SELAYANG SUB-DISTRICT","authors":"Andri Josua Barutu, Heru Rahmadhany","doi":"10.32734/sumej.v5i3.8040","DOIUrl":"https://doi.org/10.32734/sumej.v5i3.8040","url":null,"abstract":"Background. Low back pain is defined as feeling of pain and discomfort in the area between the costal margin and inferior gluteal fold, with or without radiating pain. In Indonesia, LBP was fifth ranks in term of disability-adjusted life years (DALYs). Aim. This study aims to determine risk factors for LBP in employees of drinking water store in Medan Selayang sub-District, Medan. Method. This research is an observational analytic study with cross-sectional design. This study used consecutive sampling method. Minimum sample size in this study was 97 samples. Subjects in this study were employees of drinking water store in Medan Selayang sub-District. Data used in this study was primary data from samples through filling out questionnaires. Analysis used in this study was univariate analysis, bivariate with chi-square, and multivariate with logistic regression. Result. From 100 samples, 39 respondents (39%) experienced LBP. Based on bivariate analisis, p value ≤ 0.05 was found  for age, body mass index, and duration of work. P value ≥ 0.05 was obtained for years of work and lifting frequency. Based on multivariate analysis with regression logistic, p value ≤ 0.05 was obtained for body mass index (p = 0.089) and work duration (p = 0.011) which indicated that work duration was the most dominant risk factor. Conclusion. There’s a relationship between age, body mass index, and work duration with the work duration being the most dominant risk factor for the incidence of low back pain in water gallon worker. .  ","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133125285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Diabetic Retinopathy Degree With Visual Acuity And Retinal Nerve Fiber Layer Thickness In Type 2 Diabetes Mellitus Patients","authors":"Felanda Ahsanu Nadia","doi":"10.32734/sumej.v5i3.9190","DOIUrl":"https://doi.org/10.32734/sumej.v5i3.9190","url":null,"abstract":"Introduction: Diabetic retinopathy is an ocular complication of diabetes mellitus (DM), and is one of the leading causes of visual impairment and blindness worldwide.. More than one third of people with diabetes have signs of diabetic retinopathy. \u0000  \u0000Methods: This was an analytic observational study with cross-sectional design. The sample was type 2 diabetes mellitus patients with diabetic retinopathy who visited the eye clinic at the University of Sumatera Utara General Hospital from September 2021-December 2021. The sample were then analyzed with the Mann-Whitney and Kruskal Wallis test to find the relationship between diabetic retinopathy degree with visual acuity and retinal nerve fiber layer thickness in type 2 diabetes mellitus patients. \u0000  \u0000Results: The sample of this study were 20 subjects with diabetic retinopathy and 20 subjects without diabetic retinopathy as the control group. The mean visual acuity in subjects with mild diabetic retinopathy was 0.65+0.48. Average visual acuity in subjects with the degree of moderate diabetic retinopathy was 0.83+0.46. The mean visual acuity in subjects with a proliferative degrees diabetic retinopathy was 0.77+0.64. Mann Whitney test revealed no statistically significant relationship between the degree of diabetic retinopathy and visual acuity (p=0.734). Using the Kruskal Wallis test revealed that there was no significant relationship between the degree of retinopathy diabetic with Avg RNFL (p=0.495), superior RNFL (p=0.385), inferior RNFL (p=0.111), temporal RNFL (p=0.064), nasal RNFL (p=0.535). \u0000  \u0000Discussion: Controlling blood glucose levels becomes more important than the duration of diabetes in preventing the development of retinopathy. Most patients are advised to have an HbA1c of 7% or lower, and for certain patients it is recommended to be lower than6.5%. Diabetic retinopathy slowly damages the retinal blood vessels or the optic nerve layer, leading to leakage, thus resulting in accumulation of fluid containing lipid and blood in the retina which will gradually lead to visual impairment, and even blindness. \u0000  \u0000Conclusion: There is no significant relationship between diabetic retinopathy degree with visual acuity and retinal nerve fiber layer thickness in type 2 diabetes mellitus patients.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116690275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Comparison Level of Parent’s Knowledge Towards Interdigital Tinea Pedis (Athlete’s foot) in Parents with and without Interdigital Tinea Pedis in Namu Trasi","authors":"Meirin Yustisya","doi":"10.32734/sumej.v5i3.7925","DOIUrl":"https://doi.org/10.32734/sumej.v5i3.7925","url":null,"abstract":"Background: Tinea pedis occurs in 30-70% of the world's population. In Indonesia, some data are known, such as statistical data on the prevalence of tinea pedis in several teaching hospitals, such as RS. Dr. Soetomo, RSCM, RS. Dr. Hasan Sadikin, RS. Dr. Sardjito obtained a relative yield of 16%. Therefore, public knowledge about tinea pedis is something that is very relatively owned by the community to respond to, control, and prevents the occurrence of tinea pedis. Objective: The purpose of this study was to compare the level of parental knowledge of Interdigital Tinea Pedis (Athlete’s foot) in parents with and without Interdigital Tinea pedis in Namu Trasi. Method: This research was conducted using an analytical method of cross-sectional design with a collection technique using a questionnaire to be filled out by the respondent and then analyzed using a statistical program application.  Results: The level of knowledge of parents with and without Interdigital Tinea pedis in Namu Trasi Village was 45.8% with good knowledge, 34.7% with sufficient knowledge, and 19.4% with poor knowledge. Conclusion: There is a significant difference between the level of parental knowledge of Interdigital Tinea pedis (Athlete’s foot) in patients and non-patients with Interdigital Tinea pedis in Namu Trasi","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115094306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report The Evaluation of Malondialdehyde Level on Acne Vulgaris Treatment","authors":"Muhammad Ridlo, N. Jusuf","doi":"10.32734/sumej.v5i2.6633","DOIUrl":"https://doi.org/10.32734/sumej.v5i2.6633","url":null,"abstract":"Abstract: Acne vulgaris (AV) is a multifactorial disease of the pilosebaceous unit with varying degrees of severity, recurrent and characterized by polymorphic lesions. Recent studies have found that the etiopathogenesis of AV is caused by oxidative stress. Each factor that causes AV is interrelated and is under the control of hormones and immunity. Measurement of malondialdehyde (MDA) level in the blood becomes a biological marker or an indicator of cell and tissue damage caused by oxidative stress. Case: A 23-years-old female private employee visited the clinic for multiple comedones and papulopustular lesions scattered over cheeks, nose, and chin that spread to the whole face four months ago. There were multiple comedones, papules, pustules, nodules on the maxillary, nasalis, left and right zigomatic, mentalis and frontalis region. We also found multiple scars on the left and right buccal. She was diagnosed with Severe AV. Serum MDA level was measured according to the enzyme-linked immunosorbent assay (ELISA) method before and after therapy. She was treated with doxycycline 100 mg, 0.025% tretinoin cream, 5% benzoyl peroxide, 1.2% clindamycin gel, and broadspectrum sunscreen with SPF 50. Result: After eight weeks of treatment, there were noticeable improvements in acne lesions and overall healthier-looking skin. Serum MDA levels are decreased (22.6 nmol/ml  to 17.9 nmol/ml) as the impact of the therapy. \u0000Keyword: Acne Vulgaris, Malondialdehyde, Oxidative Stress","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"17 15-16","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133170529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}