Medecine et sante tropicales最新文献

A pain in the rear. 麻烦

Medecine et sante tropicales Pub Date : 2020-02-07 DOI: 10.1684/mst.2019.0916

A Deh, B A Diatta, S Diadie, A M Gaye, K Diop, M Ndiaye, M Diallo, O S Niang

{"title":"A pain in the rear.","authors":"A Deh, B A Diatta, S Diadie, A M Gaye, K Diop, M Ndiaye, M Diallo, O S Niang","doi":"10.1684/mst.2019.0916","DOIUrl":"10.1684/mst.2019.0916","url":null,"abstract":"Tuberculosis is an endemic disease in Senegal. Cutaneous forms are rare and are characterized by their clinical polymorphism. They account for 2% of the extrapulmonary locations of tuberculosis [1, 2]. We report an observation of a tuberculous gumma of the buttock that led to the discovery of an active pulmonary localization in an immunocompetent adult. A 47-year-old man was admitted for a painful swelling of the right buttock that had been developing for four years. The physical examination noted an indurated, multinodular, and polyfistulized plaque, with confluent yellowish pus emission, on the inferomedial face of the right buttock, associated with bilateral inguinal lymphadenopathy. Cutaneous tuberculosis was found in the histology, which showed TB granuloma, and the gastric tube fluid was positive for acid-fast bacilli. Thoracoabdominopelvic CT showed multiple basal acinar micronodules in both lungs. Serology was negative for both HIV and HBV. All signs of tuberculosis disappeared after six months of treatment. In endemic zones, cutaneous tuberculosis is characterized by its clinical polymorphism. It must also be looked for in any perineal abscess. Early management greatly improves the prognosis.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37630672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Human Gastrointestinal Microbiota by Culturomics in Africa. 非洲人类胃肠道微生物群的培养组学研究。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0943

S I Traoré, M Bilen, F Cadoret, S Khelaifia, M Million, D Raoult, J C Lagier

{"title":"Study of Human Gastrointestinal Microbiota by Culturomics in Africa.","authors":"S I Traoré, M Bilen, F Cadoret, S Khelaifia, M Million, D Raoult, J C Lagier","doi":"10.1684/mst.2019.0943","DOIUrl":"https://doi.org/10.1684/mst.2019.0943","url":null,"abstract":"The interest in studying gut microbiota has been rekindled with the advent of molecular techniques, in particular, metagenomics. Culturomics (high throughput microbial culture with identification of the colonies by Maldi-TOF) has demonstrated its complementarity with metagenomics for comprehensive study of the microbiota. The main metagenomic studies have revealed an increase in biodiversity, with in particular an increase of Spirochaetes and Prevotella in subjects of African origin compared with Western subjects. Studies on malnutrition have shown a reduction of all bacteria and in particular of anaerobic bacteria and methanogenic archaea. Of the 1,162 bacteria isolated by culturomics studies, 476 were isolated only from non-African samples, 445 were isolated in African and non-African groups, and 241 bacteria were isolated from samples of African origin including 68 new species. Further studies of African microbiota by culturomics and metagenomics will make it possible to assess whether some bacteria have particular specificities and if these might play a role in certain pathologies such as malnutrition.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"366-370"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An atypical keloid in a Brazilian man. 一名巴西男子的非典型瘢痕疙瘩。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0947

M Garcia, R Chanlin, D Blanchet, M Demar, P Couppie, R Blaizot

引用次数: 1

Burkholderia et abcès de prostate. 前列腺伯克霍尔德氏杆菌。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0933

P Bourée

引用次数: 0

Building a center of excellence in biomedical research in an unfavorable environment: the Malaria Research and Training Center in Mali. 在不利的环境中建立一个卓越的生物医学研究中心:马里疟疾研究和培训中心。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0938

A Djimde, S Ranque, M A Thera

{"title":"Building a center of excellence in biomedical research in an unfavorable environment: the Malaria Research and Training Center in Mali.","authors":"A Djimde, S Ranque, M A Thera","doi":"10.1684/mst.2019.0938","DOIUrl":"https://doi.org/10.1684/mst.2019.0938","url":null,"abstract":"By choosing a capacity-building strategy based on human resources, the late Professor Ogobara Doumbo and Professor Yeya Toure have succeeded in establishing a center devoted to malaria research in the economically unfavorable environment of Mali. By taking advantage of the advent of a pluralist democracy in Mali in 1991, the Malaria Research and Training Centre (MRTC) has become a model of excellence in training in biomedical research and a renowned clinical research center. Since 2003, MRTC researchers have conducted more than 20 phase-1 and -2 clinical trials of antimalarial vaccines, thus becoming a reference both in Africa and globally. The MRTC owes its success to several factors. While the focus on human capacity building has been critical for sustainability, the quality of the partnerships and the density of the partnership network have also played a critical role. The NIH partnership enabled us to construct new buildings to house modern laboratories. These facilities made it possible to conduct leading-edge research programs, the results of which in turn provided access to significant other funding sources, not only to finance new projects, but also to purchase modern heavy equipment. Lastly, it has been possible to set up a policy for training Malian researchers at the Masters and PhD levels, with the aim of fueling a critical mass of scientific expertise. The combination of each of these factors has created an environment conducive to sustainable research and whose recent results have heightened expectations for a rich future.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"343-347"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

New technologies for controlling emerging infectious diseases in Guinea and the Democratic Republic of the Congo: their role in response to the Ebola epidemic. 几内亚和刚果民主共和国控制新出现传染病的新技术:它们在应对埃博拉疫情中的作用。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0942

A Ayouba, P Mbala-Kingebeni, A K Keita, N Vidal, A Lacroix, A Touré, J-J Muyembe-Tamfum, E Delaporte, M Peeters, S Ahuka-Mundeke

{"title":"New technologies for controlling emerging infectious diseases in Guinea and the Democratic Republic of the Congo: their role in response to the Ebola epidemic.","authors":"A Ayouba, P Mbala-Kingebeni, A K Keita, N Vidal, A Lacroix, A Touré, J-J Muyembe-Tamfum, E Delaporte, M Peeters, S Ahuka-Mundeke","doi":"10.1684/mst.2019.0942","DOIUrl":"https://doi.org/10.1684/mst.2019.0942","url":null,"abstract":"Emerging infectious diseases appear recurrently and represent a threat to global health security. Africa is particularly exposed to the risks of infectious epidemics, due to both the number of circulating infectious agents, especially in wildlife, and the social and environmental factors that promote their epidemic spread. Ebola outbreaks in West Africa in 2014 and those in the DRC that began in 2018 were an opportunity to develop and deploy new diagnostic techniques in laboratories in Guinea and the Democratic Republic of the Congo (DRC). These tools made it possible to identify the infectious agent rapidly, to trace contamination chains in real time to enable effective interventions, and to develop a reliable serological tool for differential diagnoses. Today, equipped and functional facilities exist in both countries, led by Guinean and Congolese researchers trained to high levels of competence and benefiting from unique experience and field knowledge.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"362-365"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Occurrence of phlebitis related to peripheral venous catheterization in the emergency services of the Souro Sanou National Teaching Hospital in Burkina Faso. 布基纳法索souo Sanou国立教学医院急诊服务中与外周静脉导管置入相关的静脉炎的发生

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0927

Z C Méda, S T A Thiombiano, H Hien, L Hien, I Traoré, B Ilboudo, L Couibaly, H Kpoda, L Sakana, G B L Savadogo, I Sombié

{"title":"Occurrence of phlebitis related to peripheral venous catheterization in the emergency services of the Souro Sanou National Teaching Hospital in Burkina Faso.","authors":"Z C Méda, S T A Thiombiano, H Hien, L Hien, I Traoré, B Ilboudo, L Couibaly, H Kpoda, L Sakana, G B L Savadogo, I Sombié","doi":"10.1684/mst.2019.0927","DOIUrl":"https://doi.org/10.1684/mst.2019.0927","url":null,"abstract":"Patients must receive high-quality and safe health care. Peripheral venous catheterization (PVC) exposes patients to complications, mostly phlebitis. This study investigated the incidence of phlebitis and its PVC-related risk factors among patients in the medical and surgical emergency departments of the Souro Sanou University Hospital Center (CHUSS) in Bobo Dioulasso, Burkina Faso. This prospective cross-sectional study took place from July 4 to August 3, 2018. The incidence of PVC-related phlebitis was calculated and its risk factors were identified by logistic regression, with SPSS software version 20 (entry option), with significance set at 5%. The 511 patients included in the study had a mean age of 44.7 (95% CI 43.1-46.3) years. The mean duration of PVC was 3.1 days. Of these patients, 149 developed phlebitis, for an incidence of 29.2% (95% CI 25.0%-33.0%). There was no statistically significant difference between the two emergency (medical and surgical) departments. Second-degree phlebitis accounted for slightly more than half the cases (53%). Risk factors associated with the occurrence of PVC-related phlebitis were female gender, catheterization duration more than 3 days, small size of the catheter, and the healthcare worker's failure to use friction in washing with a hydroalcoholic hand solution. Preventive measures are essential.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"424-430"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequelae of thoracic tuberculosis: manifestations and patients'quality of life. 胸结核后遗症:表现与患者生活质量。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0949

M Fafa Cisse, Y Dia Kane, I N Abessolo Amougou, F B Mbaye, K Thiam, N O Touré

{"title":"Sequelae of thoracic tuberculosis: manifestations and patients'quality of life.","authors":"M Fafa Cisse, Y Dia Kane, I N Abessolo Amougou, F B Mbaye, K Thiam, N O Touré","doi":"10.1684/mst.2019.0949","DOIUrl":"https://doi.org/10.1684/mst.2019.0949","url":null,"abstract":"For many patients, a history of tuberculosis is synonymous with disabling sequelae, impaired quality of life, and high morbidity and mortality. This retrospective study reviewed the files of patients hospitalized for sequelae of thoracic tuberculosis during 2017, to assess its various manifestations and their impact on quality of life. Of the 176 patients included, 75 % were aged from 35 to 65 years. They were predominantly male, with a sex ratio of 3.76. The socioeconomic level was mostly low (70 %). Only one episode of tuberculosis sufficed to cause sequelae in 89.8 % of cases. Smoking was often noted (52.3 %). Functional signs were dominated by coughs (90.3 %) and dyspnea (72.7 %). Pulmonary sequelae with fibrous scarring were observed in 52.2 % of the patients. Bacterial and/or viral superinfection was the leading cause of hospitalization (50 %). The death rate during hospitalization was 19 %. An improvement followed by discharge was observed for 81 %, 14.2 % of them with chronic respiratory insufficiency. In all, 13.28 % of the discharged patients died within the 6 months that followed. The sequelae of thoracic tuberculosis should be considered as long-term chronic conditions and deserve the same treatment.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"440-445"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The University Hospital Institute Mediterrannée Infection from Marseille to Dakar. 大学医院研究所研究了从马赛到达喀尔的地中海感染。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0941

C Sokhna, H Basséne, G Diatta, N Diagne, S Doucouré, A Diallo, E H Ba, F Fenollar, O Mediannikov, P Gautret, M Drancourt, J-C Lagier, D Raoult, P Parola

{"title":"The University Hospital Institute Mediterrannée Infection from Marseille to Dakar.","authors":"C Sokhna, H Basséne, G Diatta, N Diagne, S Doucouré, A Diallo, E H Ba, F Fenollar, O Mediannikov, P Gautret, M Drancourt, J-C Lagier, D Raoult, P Parola","doi":"10.1684/mst.2019.0941","DOIUrl":"https://doi.org/10.1684/mst.2019.0941","url":null,"abstract":"In Senegal, we have developed technology-driven research based on observation and technology transfer especially in molecular biology, genomics, culturomics, and proteomics with the use of the first Maldi-TOF mass spectrometer in clinical microbiology in Africa. This strategy is associated with a policy of training students from the South and helping them to return back. This technology transfer and expertise has enabled us to explore the causes of non-malarial fevers of unknown causes, with the study of the repertoire of infectious pathogens in humans and arthropod vectors, to diagnose infectious diseases in rural areas with Point of Care laboratories, to isolate new bacteria, and to study pathologies linked to mass gatherings. They have also allowed us to develop transdisciplinary research including the study of the microbiota in malnourished children. We wish to continue this technological development, which provides the foundation for high-level research in Senegal.","PeriodicalId":18307,"journal":{"name":"Medecine et sante tropicales","volume":"29 4","pages":"354-360"},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37498277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Nutritional approach to management of Buruli ulcer in Côte d'Ivoire. Côte科特迪瓦布鲁里溃疡的营养管理方法。

Medecine et sante tropicales Pub Date : 2019-11-01 DOI: 10.1684/mst.2019.0935

Y D Koffi, A G Konan, J Delmont, A A Adjet, J L Rey

引用次数: 0