Journal of Cytology / Indian Academy of Cytologists最新文献_第7页

Endometrial aspiration cytology in gynecological disorders 子宫内膜抽吸细胞学在妇科疾病中的应用

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175488

M. Jadhav, Anjali S. Phatke, N. Kadgi, S. R. Rane, K. Kulkarni

{"title":"Endometrial aspiration cytology in gynecological disorders","authors":"M. Jadhav, Anjali S. Phatke, N. Kadgi, S. R. Rane, K. Kulkarni","doi":"10.4103/0970-9371.175488","DOIUrl":"https://doi.org/10.4103/0970-9371.175488","url":null,"abstract":"Context: Endometrial aspiration is not a popular modality for the study of the endometrium despite its simplicity and potential utility. Aim: The present study was aimed at evaluating the utility of endometrial aspiration in various gynecological disorders. Materials and Methods: In this diagnostic accuracy study, 55 prospectively registered women with various gynecological disorders were evaluated clinically and subjected to endometrial aspiration cytology and study of endometrial histology. Endometrial aspiration was performed by infant feeding tube in 10 cases and intra cath cannula in 45 cases. The slides were stained with rapid Papanicolaou (PAP) stain and Leishman stain. Results: Endometrial aspiration cytology showed 90% and 94.6% sampling adequacy with infant feeding tube and intra cath cannula, respectively. Intra cath cannula was very convenient to handle and superior to infant feeding tube in aspirating the endometrium. Of the two stains used, rapid PAP stain was less time-consuming and superior to Leishman stain in studying the nuclear details. Leishman stain was helpful in detecting cytoplasmic vacuoles of secretory endometrium. Overall diagnostic accuracy of endometrial cytology was 90.4% while that for morphological hormonal evaluation was 97.6%. It enjoyed a sensitivity of 91.66%, a specificity of 88.23%, positive predictive value of 94.28%, and negative predictive value of 83.33%. Conclusion: Intra cath cannula emerged as an inexpensive, effective, and convenient device for endometrial aspiration. Endometrial aspiration proved to be a fairly effective, simple, and informative diagnostic modality.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123611861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Fine needle aspiration cytology of dermatopathic lymphadenitis in an asymptomatic female: A case report 无症状女性皮肤病性淋巴结炎细针吸细胞学分析1例

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175523

B. Srinivasamurthy, K. Saha, Swagatika Senapati, A. Saha

引用次数: 7

Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait 科威特非小细胞肺癌患者表皮生长因子受体突变

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175476

R. Al-Temaimi, K. Kapila, F. Al-Mulla, I. Francis, S. Al-Waheeb, B. Al‐Ayadhy

{"title":"Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait","authors":"R. Al-Temaimi, K. Kapila, F. Al-Mulla, I. Francis, S. Al-Waheeb, B. Al‐Ayadhy","doi":"10.4103/0970-9371.175476","DOIUrl":"https://doi.org/10.4103/0970-9371.175476","url":null,"abstract":"Context: Nonsmall cell lung carcinoma (NSCLC) is the most frequently diagnosed form of lung cancer in Kuwait. NSCLC samples from Kuwait have never been screened for epidermal growth factor receptor (EGFR) gene aberration, which is known to affect treatment options. Aims: This study investigated the feasibility of using fine-needle aspiration (FNA) material for mutational screening, and whether common EGFR mutations are present in NSCLC samples from Kuwait. Settings and Design: Eighteen NSCLC samples from five Kuwaitis and 13 non-Kuwaitis were included in this study. Materials and Methods: DNA was extracted from FNA cell blocks and screened for EGFR gene mutations using peptide nucleic acid (PNA)-clamp assay, and EGFR gene amplification using fluorescent in situ hybridization (EGFR-FISH). EGFR protein expression was assessed using immunohistochemistry. Results: Five EGFR mutations were detected in five non-Kuwaiti NSCLC patients (27.8%). EGFR gene amplification was evident in 10 samples (55.5%) by direct amplification or under the influence of chromosomal polysomy. Four samples had EGFR mutations and EGFR gene amplification, out of which only one sample had coexisting EGFR overexpression. Conclusions: Given the evidence of EGFR gene alterations occurring in NSCLC patients in Kuwait, there is a need to incorporate EGFR gene mutational screen for NSCLC patients to implement its consequent use in patient treatment.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125792547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Fine-needle aspiration cytology of cutaneous granular cell tumor: Report of two cases with special emphasis on cytological differential diagnosis 皮肤颗粒细胞瘤的细针穿刺细胞学检查:附2例报告，特别强调细胞学鉴别诊断

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175497

U. Khurana, U. Handa, H. Mohan

引用次数: 5

Erratum: Intraoperative diagnosis of central nervous system lesions: Comparison of squash smear, touch imprint, and frozen section 勘误:术中中枢神经系统病变的诊断:挤压涂片、触印和冰冻切片的比较

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175533

引用次数: 1

Fine needle aspiration cytology of chondroblastoma: A report of two cases with brief review of pitfalls 成软骨细胞瘤的细针穿刺细胞学:两例报告并简要回顾其缺陷

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175514

A. Krishnappa, S. Shobha, SVijay Shankar, Sushma Aradhya

引用次数: 9

Review of the touch preparation cytology of spindle epithelial tumor with thymus-like differentiation 胸腺样分化梭形上皮肿瘤触觉准备细胞学研究进展

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175495

Kijong Yi, A. Rehman, S. Jang, S. Paik

{"title":"Review of the touch preparation cytology of spindle epithelial tumor with thymus-like differentiation","authors":"Kijong Yi, A. Rehman, S. Jang, S. Paik","doi":"10.4103/0970-9371.175495","DOIUrl":"https://doi.org/10.4103/0970-9371.175495","url":null,"abstract":"We experienced a case of spindle epithelial tumor with thymus-like differentiation (SETTLE) with touch preparation cytology performed during the intraoperative frozen section diagnosis in a 22-year-old woman. The tumor was partially encapsulated by fibrous capsule. It was a highly cellular biphasic tumor characterized by fasciculated spindle cells with streaming pattern and tubulopapillary epithelial component. The tumor cells were positive for cytokeratin, vimentin, c-kit, epithelial membrane antigen (EMA), and thyroid transcription factor-1 (TTF-1). However, the tumor cells were negative for thyroglobulin, calcitonin, CD99, S-100 protein, CD34, smooth muscle actin, HBME-1, and galectin-3. The reviewed touch smears showed tight clusters with high cellularity. Most cellular clusters showed papillary configuration. However, some clusters showed spindle cells with streaming pattern. The spindle tumor cells showed elongated and cigar-shaped nuclei. Although the incidence is very rare, SETLLE should be included in the differential diagnosis when a spindle cell neoplasm is encountered in touch preparation cytology in young patients with a thyroid mass.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124201776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Cytodiagnosis of primary cutaneous aspergillosis in an immunocompetent host 免疫正常宿主原发性皮肤曲霉病的细胞诊断

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175532

P. Rocha, R. G. Pinto, S. Rodrigues, M. J. Rodrigues, Adhisha Ambili Sudhakaran, Kanika Mahajan

引用次数: 4

Utility of fine-needle aspiration cytology in the identification of parathyroid lesions 细针穿刺细胞学在甲状旁腺病变鉴别中的应用

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175490

N. Kumari, Deepti Mishra, Roma V Pradhan, A. Agarwal, N. Krishnani

{"title":"Utility of fine-needle aspiration cytology in the identification of parathyroid lesions","authors":"N. Kumari, Deepti Mishra, Roma V Pradhan, A. Agarwal, N. Krishnani","doi":"10.4103/0970-9371.175490","DOIUrl":"https://doi.org/10.4103/0970-9371.175490","url":null,"abstract":"Objectives: Fine-needle aspiration cytology (FNAC) is a first-line investigation in the evaluation of neck nodules. In an attempt to search for reliable cytomorphological criteria for parathyroid lesions, we systematically evaluated cytomorphology of FNAC of parathyroid lesions. Study Design: FNAC of 15 parathyroid and 15 hyperplastic thyroid nodules with histological confirmation were reviewed for following features: Cellularity, follicles, bare nuclei, cohesiveness, vascular profiles, cytoplasmic granularity, intracytoplasmic vacuolation, mitosis, macrophages, and colloid. Results: Vascular proliferation, bare nuclei, intracytoplasmic fat vacuolation, absence of colloid, and high cellularity showed significant association with parathyroid lesions (P ≤ 0.05). Intracytoplasmic fat vacuolation was 53.3% sensitive and 100% specific for parathyroid. Follicular pattern and papillaroid clusters were also important; however, they achieved nearly significant statistical difference (P = 0.05 and P = 0.06, respectively). The combination of vascular proliferation and intracytoplasmic fat vacuolation were significantly associated with parathyroid (P = 0.006) whereas the absence of bare nuclei and the presence of background colloid were associated with thyroid cytomorphology (P = 0.03). Conclusion: No single cytological feature is helpful in differentiating parathyroid from thyroid lesion. Vascular proliferation, bare nuclei, intracytoplasmic fat vacuolation, high cellularity, and the absence of colloid were significantly associated with the parathyroid origin. The combination of at least two features — vascular proliferation and intracytoplasmic fat vacuoles — were highly suggestive of parathyroid origin.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114235068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

“A fine needle aspiration cytology in time saves nine” — cutaneous phaeohyphomycosis caused by Exophiala jeanselmei in a renal transplant patient: Diagnosis by fine needle aspiration cytology “一次细针吸细胞学检查及时挽救9例”——肾移植患者由jeanselmeexophiala引起的皮肤褐丝菌病:细针吸细胞学诊断

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175529

P. Joshi, S. Agarwal, Geetika Singh, I. Xess, D. Bhowmik

引用次数: 6