Journal of Cytology / Indian Academy of Cytologists最新文献_第6页

Intraoperative diagnosis of central nervous system lesions: Comparison of squash smear, touch imprint, and frozen section 术中中枢神经系统病变的诊断:挤压涂片、触印、冰冻切片的比较

Journal of Cytology / Indian Academy of Cytologists Pub Date : 2015-07-01 DOI: 10.4103/0970-9371.168835

Vikram Nanarng, S. Jacob, Debahuti Mahapatra, J. Mathew

{"title":"Intraoperative diagnosis of central nervous system lesions: Comparison of squash smear, touch imprint, and frozen section","authors":"Vikram Nanarng, S. Jacob, Debahuti Mahapatra, J. Mathew","doi":"10.4103/0970-9371.168835","DOIUrl":"https://doi.org/10.4103/0970-9371.168835","url":null,"abstract":"Background: Intraoperative diagnosis of central nervous system (CNS) lesions is of utmost importance for neurosurgeons to modify the approach at the time of surgery and to decide on further plan of management. The intraoperative diagnosis is challenging for neuropathologists. Aims: The study was undertaken to determine the accuracy of cytological techniques (crush smears and touch imprints), frozen sections of space occupying lesions of the CNS and compare it with histopathological diagnosis. Materials and Methods: A total of 75 specimens received intraoperatively were subjected to cytology and frozen section study. Results: Neoplastic lesions formed the major group with 62 (82.7%) cases while 13 (17.3%) were nonneoplastic. The diagnostic accuracy of “squash smears” was found to be 89.2%. “Touch imprints” showed diagnostic accuracy of 78.4%. The low accuracy of touch imprints was attributed to poor cellular yield. The diagnostic accuracy of “frozen section” was 75.7%. However, the overall diagnostic accuracy was 96%. Conclusion: We believe that the cytololgical methods and frozen sections are complimentary to each other and both should be used to improve the intraoperative diagnostic accuracy in the CNS lesion.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125359641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

Author's response 作者的回应

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1994-12-01 DOI: 10.1080/00048679409080795

Neeta Kumar

引用次数: 0

Primary small cell carcinoma of the parotid: Fine needle aspiration and immunohistochemical features of a neuroendocrine variant 腮腺原发性小细胞癌:神经内分泌变异的细针穿刺和免疫组织化学特征

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175509

S. Altınay, P. Fırat, Senay Yalçin, Ümit Taşkın

引用次数: 1

Role of fine-needle aspiration cytology and core needle biopsy in diagnosing musculoskeletal neoplasms 细针穿刺细胞学和核心针活检在肌肉骨骼肿瘤诊断中的作用

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175478

Ivreet Kaur, U. Handa, R. Kundu, S. Garg, H. Mohan

{"title":"Role of fine-needle aspiration cytology and core needle biopsy in diagnosing musculoskeletal neoplasms","authors":"Ivreet Kaur, U. Handa, R. Kundu, S. Garg, H. Mohan","doi":"10.4103/0970-9371.175478","DOIUrl":"https://doi.org/10.4103/0970-9371.175478","url":null,"abstract":"Background: The management of musculoskeletal neoplasms requires an accurate diagnosis, histologic type, and degree of tumor differentiation. Aim: The present study was undertaken to compare the accuracy of fine-needle aspiration cytology (FNAC) and core needle biopsy (CNB) in the diagnosis of musculoskeletal tumors and further to compare the results with histopathological examination of surgical specimens. Grading of malignant tumors was also compared on these techniques. Materials and Methods: This prospective study was conducted on 50 patients with musculoskeletal neoplasms. Detailed history, clinical examination, and radiological investigations were undertaken. FNAC followed by CNB were performed in each case. The tumors were categorized as benign and malignant with a definitive histotype diagnosis. For malignant neoplasms, cytologic and histologic gradings were done into three grades. The sensitivity and specificity of FNAC and CNB were compared. Results: Of the 50 cases with musculoskeletal neoplasms, 32 (64%) were bone tumors and 18 (36%) were soft tissue tumors. The sensitivity of FNAC and CNB for categorizing bone tumors into benign and malignant was 94.7%. For soft tissue tumors, FNAC had a sensitivity of 90.9% and CNB had a sensitivity of 100%. The specificity of both the techniques, FNA and CNB for bone and soft tissue tumors was 100%. For malignant bone tumors, cytologic grade was concordant with CNB grade in 72.2% of the cases. Cytologic grade was concordant with the grade on CNB in 81.8% cases for malignant soft tissue neoplasms. Conclusion: FNAC and CNB alleviate the need for an open biopsy in diagnosing and grading musculoskeletal neoplasms, thus facilitating appropriate therapeutic intervention.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114958099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: A cytological dilemma 甲状腺嗜酸性粒细胞增多的硬化性黏液表皮样癌:细胞学上的困境

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175511

Chayanika Pantola, S. Kala, M. Athar, S. Thakur

引用次数: 14

Preoperative cytological diagnosis of mucinous carcinoma (MC) of male breast 男性乳腺粘液癌的术前细胞学诊断

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175531

P. Pawar, S. Poflee, Nandu P. Pande, A. Shrikhande

{"title":"Preoperative cytological diagnosis of mucinous carcinoma (MC) of male breast","authors":"P. Pawar, S. Poflee, Nandu P. Pande, A. Shrikhande","doi":"10.4103/0970-9371.175531","DOIUrl":"https://doi.org/10.4103/0970-9371.175531","url":null,"abstract":"We report a case of MC diagnosed preoperatively on the basis of cytology findings. A 60-year-old male with slowly enlarging, subareolar lump in left breast was referred for fine needle aspiration cytology (FNAC) presuming it to be gynecomastia. He had no other complaints, no history of any major illness in the past. The breast swelling was 1 cm × 1 cm, well-defined, mobile and firm in consistency. Cytology smears revealed moderate cellularity in the background of abundant mucinous material and chicken wire-like blood vessels [Figure 1a]. The cells were seen in groups, dispersed individually, showed moderate cytoplasm, large, round to oval eccentric nuclei with regular nuclear membrane, granular chromatin and one to two prominent nucleoli [Figure 1b]. Cytodiagnosis of MC was offered. Preoperative mammography and sonography revealed lobulated, hyperechoic mass in the central part of the left breast. On extensive clinical and radiological study, no mass lesion was found at any other body site. The patient’s modified radical mastectomy specimen showed a subareolar glistening white, firm tumor, of size 1.5 cm × 1.5 cm, along with six subcentimetric lymph nodes and axillary fat. Histopathology sections revealed malignant cells arranged in groups and cords within pools of mucin. Lymph nodes did not show evidence of metastasis. The diagnosis of primary MC of the breast was confirmed.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124630076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Primary granulosa cell tumor of retroperitoneal origin: A rare presentation with emphasis on cytomorphology 原发性腹膜后颗粒细胞瘤:一种罕见的表现，强调细胞形态学

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175527

P. Vasu, J. Leelamma, B. Mohammed, Jyotsna Yesodharan

{"title":"Primary granulosa cell tumor of retroperitoneal origin: A rare presentation with emphasis on cytomorphology","authors":"P. Vasu, J. Leelamma, B. Mohammed, Jyotsna Yesodharan","doi":"10.4103/0970-9371.175527","DOIUrl":"https://doi.org/10.4103/0970-9371.175527","url":null,"abstract":"The most frequently occurring retroperitoneal tumors are those of the kidneys, adrenal glands, and the pancreas. A primary retroperitoneal tumor composed of granulosa cells and developing far away from the normal location of the ovary is less frequently observed. A 69-year-old female patient presented with abdominal discomfort. Computerized tomography (CT) of the abdomen revealed a solid heterogeneous mass lesion measuring 11.2 cm × 8 cm × 12 cm consistent with retroperitoneal hematoma. Ultrasonography (USG)-guided aspiration smears revealed cytological features suggestive of adult-type granulosa cell tumor (AGCT). As the patient had a history of hysterectomy with bilateral salpingo-oophorectomy 22 years ago for leiomyoma, a diagnosis of extraovarian AGCT was made. Intraoperatively, the tumor was removed in piecemeal that showed yellowish areas with extensive necrosis and hemorrhage. Histopathological examination of the excised mass and inhibin positivity confirmed the diagnosis. Primary retroperitoneal extraovarian GCT is a rare tumor with only 12 cases reported in medical literature in English.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122959021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Utility of conventional transbronchial needle aspiration with rapid on-site evaluation (c-TBNA-ROSE) at a tertiary care center with endobronchial ultrasound (EBUS) facility 传统经支气管针吸与快速现场评估(c- tna - rose)在三级保健中心与支气管内超声(EBUS)设施的应用

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175493

N. Madan, K. Madan, D. Jain, R. Walia, A. Mohan, V. Hadda, S. Mathur, V. Iyer, G. Khilnani, R. Guleria

{"title":"Utility of conventional transbronchial needle aspiration with rapid on-site evaluation (c-TBNA-ROSE) at a tertiary care center with endobronchial ultrasound (EBUS) facility","authors":"N. Madan, K. Madan, D. Jain, R. Walia, A. Mohan, V. Hadda, S. Mathur, V. Iyer, G. Khilnani, R. Guleria","doi":"10.4103/0970-9371.175493","DOIUrl":"https://doi.org/10.4103/0970-9371.175493","url":null,"abstract":"Background: Conventional transbronchial needle aspiration (c-TBNA) is an underutilized bronchoscopic modality. Endobronchial ultrasound (EBUS) guided-TBNA though efficacious is an expensive modality, facilities of which are available at only limited centers. c-TBNA is cost-effective and has potential for wide utilization especially in resource-limited settings. Rapid on-site evaluation (ROSE) improves the yield of c-TBNA. Materials and Methods: A retrospective review of the bronchoscopy records (May 2012 to July 2014) was performed. The patients who underwent c-TBNA with ROSE were included in the study and their clinical details were extracted. Convex probe EBUS-TBNA was being regularly performed during the study period by the operators performing c-TBNA. Results: c-TBNA with ROSE was performed in 41 patients with mean age of 42.4 (16.2) years. The most frequently sampled node stations (>90% patients) were the subcarinal and lower right paratracheal. Representative samples could be obtained in 33 out of the 41 patients (80.4%). c-TBNA was diagnostic in 32 [tuberculosis (TB)-8, sarcoidosis-9, and malignancy-15] patients out of the 41 patients. The overall diagnostic yield (sensitivity) of c-TBNA with ROSE was 78%. Mean procedure duration was 18.4 (3.1) min and there were no procedural complications. Conclusion: c-TBNA with ROSE is a safe, efficacious, and cost-effective bronchoscopic modality. When it was performed by operators routinely performing EBUS-TBNA, diagnostic yields similar to that of EBUS-TBNA can be obtained. Even at the centers where EBUS facilities are available, c-TBNA should be routinely performed.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122986808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Unusual presentation of filariasis as an abscess: A case report 罕见的丝虫病表现为脓肿:1例报告

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175520

M. Ahuja, S. Pruthi, Renu Gupta, P. Khare

引用次数: 8

Metastatic prostatic adenocarcinoma diagnosed in a bronchoalveolar lavage specimen: An unusual presentation of a common tumor 支气管肺泡灌洗标本中诊断的转移性前列腺癌:常见肿瘤的不寻常表现

Journal of Cytology / Indian Academy of Cytologists Pub Date : 1900-01-01 DOI: 10.4103/0970-9371.175517

Adrienne E. Moul, C. Rojas, C. Kovacs, P. Ganjei‐Azar

{"title":"Metastatic prostatic adenocarcinoma diagnosed in a bronchoalveolar lavage specimen: An unusual presentation of a common tumor","authors":"Adrienne E. Moul, C. Rojas, C. Kovacs, P. Ganjei‐Azar","doi":"10.4103/0970-9371.175517","DOIUrl":"https://doi.org/10.4103/0970-9371.175517","url":null,"abstract":"Metastatic prostatic adenocarcinoma presenting as a primary lung disease is rare. We present a 52-year-old male with a 3-month history of cough, shortness of breath, and weight loss with clinical and radiological findings suggestive of a primary lung disease: Bilateral interstitial and alveolar opacities with blunting of the costophrenic angles, multiple diffuse foci of consolidations and nodules, predominantly subpleural and located in the lower lobes, and diffuse interlobular septal thickening and peribronchial thickening. The patient underwent bronchoscopy and bronchoalveolar lavage (BAL) was obtained. Cytospin smears were diagnostic for a low-grade adenocarcinoma. Clinically, the patient had elevated serum prostate-specific antigen (PSA) levels greater than 5,000 ng/mL. Because of this, immunocytochemistry for PSA was performed which was positive, confirming the diagnosis of metastatic prostatic adenocarcinoma. This unusual case of metastatic adenocarcinoma of the prostate first diagnosed by BAL highlights the significance of available clinical information and the use of immunocytochemistry for proper diagnosis.","PeriodicalId":182593,"journal":{"name":"Journal of Cytology / Indian Academy of Cytologists","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129039729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0