Mansoura Journal of Forensic Medicine and Clinical Toxicology最新文献_第6页

Effects of Environmental Exposure to Lead and Cadmium on Male Fertility 环境接触铅和镉对男性生育能力的影响

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47202

A. Zaki, Fouad Aldabah, Mostafa Mohammad, T. Emran, A. Amer

{"title":"Effects of Environmental Exposure to Lead and Cadmium on Male Fertility","authors":"A. Zaki, Fouad Aldabah, Mostafa Mohammad, T. Emran, A. Amer","doi":"10.21608/mjfmct.2018.47202","DOIUrl":"https://doi.org/10.21608/mjfmct.2018.47202","url":null,"abstract":"Chronic exposure to heavy metals represents a medical challenge especially in developing countries. The aim of the present study was to measure the levels of (lead and cadmium) in infertile male and correlate these levels with male fertility. After free informed consent, the present study included 70 infertile couples (without female infertility factor) attending the infertility clinics (Dermatology and Venereology Department; Al-Azhar Faculty of Medicine; New Damietta); who were well-known to be exposed to lead and/or cadmium confirmed by measuring blood lead and cadmium levels, and another 30 healthy fertile males without evidence of environmental exposure were included as controls. All patients underwent history taking, clinical and andrological examination and laboratory investigations (complete blood count, blood glucose level, renal and liver function tests and hormonal profile (serum FSH, LH, estrogen and testosterone) with measurement of lead and cadmium levels using graphite furnace atomic absorption spectrophotometry. Finally, a sample of semen was obtained for semen analysis. It was concluded that there was high concentrations of lead and cadmium linked to male infertility as revealed by changes in hormonal profile and seminal parameters.","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86378880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Determination of Blood Age by Morphological Changes of Different White Blood Cells 不同白细胞形态变化测定血龄

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47197

Hayam Z. Thabet, Nagwa M. Ghandour, M. Bakr

引用次数: 0

L-Carnitine as an Adjuvant Treatment in Acute Organophosphorus Pesticides Poisoning: A Randomized Clinical Trial 左旋肉碱辅助治疗急性有机磷农药中毒:一项随机临床试验

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.46999

Mona M. Ghonem, H. Lashin, Aliaa Hodeib, N. Soliman

引用次数: 7

Estimation of Postmortem Interval from mRNA Degradation and Autolytic Changes in the Brain and Adrenal Gland 脑和肾上腺mRNA降解和自溶变化对死后时间间隔的估计

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47198

D. Ali, O. Hassan, M. Ramzy, N. Zenhom

引用次数: 4

Study of the Causes of Mortality in Acute Aluminium Phosphide Poisoning 急性磷化铝中毒死亡原因的研究

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47196

Hany M. Tawfik

{"title":"Study of the Causes of Mortality in Acute Aluminium Phosphide Poisoning","authors":"Hany M. Tawfik","doi":"10.21608/mjfmct.2018.47196","DOIUrl":"https://doi.org/10.21608/mjfmct.2018.47196","url":null,"abstract":"Aluminum phosphide (ALP) poisoning has aroused interest in the past three decades. The percentage of poisoning is low, but the mortality is high and no effective antidote available. The objective of this study was to find out predictors of mortality for patients with acute aluminium phosphide poisoning. All patients with acute aluminium phosphide poisoning admitted to Poisoning Control Center, Ain Shams University Hospital between the years 2015 to 2017 were prospectively studied and compared between survival and non survivor patients. Data collected include demographic data, clinical manifestations, laboratory parameters, ECG and treatment offered to the patients. A total 31 patients were enrolled comprising 20 males and 11 females, 84% were suicide and mortality rate was 35%. Shock and cardiac arrhythmia were observed in 52% and39% respectively, while 26% presented with coma. Abnormal blood sugar and metabolic acidosis were found in 19% and 45% respectively. Fifty two percent of the patients needed inotropic therapy and 32% received N-acetylcysteine (NAC). Risk factors increasing mortality were found as shock, tachycardia, coma, metabolic acidosis, hyperglycemia, cardiac arrhythmia and the need for inotropic drug therapy. The study concluded that aluminum phosphide is a low-cost highly-toxic rodenticide. The circulatory collapse, metabolic acidosis and cardiac arrhythmia are the major causes of death. The role of NAC must be reassessed in larger scale. So, intensive observation in ICU and aggressive symptomatic management should be urgently taken into consideration.","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90707048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Medicolegal Importance of the Foramen Ovale, in Determination of Sex, in Dried Adult Egyptians Human Skulls (Morphometric & Morphological Study) 卵圆孔在干燥的埃及成年人头骨性别测定中的法医学意义(形态计量学和形态学研究)

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.46828

A. Nagy, Ashraf Nasr A.Y, Abdelmoty Kabbash

引用次数: 2

Incidence and Factors Influencing Acute Tramadol Toxicity-Inducing Seizures in Damietta Governorate 达米埃塔省曲马多中毒致急性癫痫发作的发生率及影响因素

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47200

Hamada Adree, Fouad Aldabah, Waleed E Abo Baraka, S. Alshazly

{"title":"Incidence and Factors Influencing Acute Tramadol Toxicity-Inducing Seizures in Damietta Governorate","authors":"Hamada Adree, Fouad Aldabah, Waleed E Abo Baraka, S. Alshazly","doi":"10.21608/mjfmct.2018.47200","DOIUrl":"https://doi.org/10.21608/mjfmct.2018.47200","url":null,"abstract":"An increased rate of seizures due to tramadol poisoning has been observed. However, the actual incidence and related factors are not well-studied. The purpose of this work was to investigate the relationship between the incidence of seizures and plasma tramadol level in patients with tramadol-inducing seizures. In addition, we reported the pattern of tramadol overdoses in selected patients. The study was conducted from 1st January 2017 to 28th February 2018. It involved 102 cases who recruited from toxicological units of AlAzhar University Hospital (New Damietta). After free informed consent to contribute in this study and within one hour after arrival to a toxicological unit, 10 mL of blood were separated and the serum was used for extraction of tramadol residues by using a highperformance liquid chromatography (HPLC) and other blood samples were stored at _ 8oC for the following assays to all patients; fasting blood sugar, hemoglobin levels, serum urea, serum creatinine and liver enzymes. Then clinical examination to all patients included vital signs with a special attention to central nervous system (CNS) manifestations, gastrointestinal (GIT) manifestation. The frequency of seizures (27.4%) with acute tramadol poisoning in humans is not dose dependent and seizures occurred with therapeutic doses and there were no relation between blood tramadol level and seizures. We concluded that risk of seizures increase in cases took other drugs with tramadol as alcohol and heroin. The frequency of seizures is not dose dependent; seizures occurred with therapeutic doses.","PeriodicalId":18180,"journal":{"name":"Mansoura Journal of Forensic Medicine and Clinical Toxicology","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87323013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Possible Correlation Between Some Chronic Pesticides Exposure and Disturbance in Thyroid Hormones Levels and Some Biochemical Markers. 某些慢性农药暴露与甲状腺激素水平及生化指标紊乱的可能相关性

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.46817

Mostafa Mohamed, K. Taha

引用次数: 0

Repeated Tramadol Administration Induced Bleeding in Albino Rats 曲马多重复给药诱导白化大鼠出血

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.47201

Hanem Roshdy, R. Abdel-Rahman, H. Azzam, A. El-Bakary

引用次数: 2

Cholinesterase Enzymes as Predictors for Severity Among Acutely Organophosphorus Intoxicated Patients 胆碱酯酶作为急性有机磷中毒患者严重程度的预测因子

Mansoura Journal of Forensic Medicine and Clinical Toxicology Pub Date : 2018-07-01 DOI: 10.21608/mjfmct.2018.46820

A. Othman, H. A. El-Atta, S. El-Hak, A. Ghanem

引用次数: 1