Macedonian Veterinary Review最新文献_第3页

Growth Dinamics on the Skin and the Coat in Normandian and Simmental Cattle During Adaptation to the Farming Technology in Southwestern Part of Bulgaria 保加利亚西南部诺曼底牛和西门塔尔牛在适应耕作技术过程中表皮和被毛的生长动态

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-12-31 DOI: 10.2478/macvetrev-2022-0029

N. Markov, S. Stoycheva, Tsvetomira Bancheva, Ljupcho Mickov, B. Atanasov, I. Esmerov, N. Adamov

{"title":"Growth Dinamics on the Skin and the Coat in Normandian and Simmental Cattle During Adaptation to the Farming Technology in Southwestern Part of Bulgaria","authors":"N. Markov, S. Stoycheva, Tsvetomira Bancheva, Ljupcho Mickov, B. Atanasov, I. Esmerov, N. Adamov","doi":"10.2478/macvetrev-2022-0029","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0029","url":null,"abstract":"Abstract The aim of the present study was to identify the adaptability of Normandy cows raised in a loose system to the climatic and technological conditions and to compare their adaptability with already acclimatized Simmental cows in one farm in Southwestern Bulgaria. Total of 20 cows at same age (II – IV lactation) and same body weight (630-660 kg) from both breeds were classified into 2 groups (each having 10 cows) and subjected to skin thickness measurement, fibers total weight determination and fiber categorization during the winter and summer season. The results have shown that during the winter season, the Normandy breed had significantly higher skin thickness at the elbow compared to the Simmental breed, whereas no differences were observed in the skin thickness between both breeds either at the neck or at the middle of the last rib. During the summer season, the differences on the skin thickness compared to the Simmental breed were observed at the neck (p<0.05), whilst at the elbow and at the middle of the last rib no differences were recorded (p>0.05). During the winter seasons, the coat of Normandy cows contained more soft fibers in comparison to the Simmentals cows. Furthermore, the changes in the observed parameters, influenced by climatic conditions showed similar pattern in both breeds. It can be concluded that the two breeds have emphasized their genetic potential and have a good adaptability to the temperate continental climate of the region.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"46 1","pages":"99 - 103"},"PeriodicalIF":0.4,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42906657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacokinetic Criteria of Ketoprofen and its Cyclooxygenase-2 Inhibition in Mice: Influence of Xylazine Administration 酮洛芬在小鼠体内的药代动力学标准及其对环氧合酶-2的抑制作用：二甲苯胺给药的影响

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-12-31 DOI: 10.2478/macvetrev-2022-0031

K. Khalil, Yaareb Jaafer Mousa, M. ALzubaidy

{"title":"Pharmacokinetic Criteria of Ketoprofen and its Cyclooxygenase-2 Inhibition in Mice: Influence of Xylazine Administration","authors":"K. Khalil, Yaareb Jaafer Mousa, M. ALzubaidy","doi":"10.2478/macvetrev-2022-0031","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0031","url":null,"abstract":"Abstract The objective of this study was to examine the effect of ketoprofen with or without combination with xylazine on the level of cyclooxygenase-2 in mice. The intraperitoneal (i.p.) dose of ketoprofen and xylazine that caused an analgesic response in half of the mouse population was 1.26 mg/kg and 6.63 mg/kg, respectively. Serum cyclooxygenase-2 concentration (activity) in the control mice was 16.94 ng/ml. The ketoprofen-treated group (2.52 mg/kg, i.p.) decreased the cyclooxygenase-2 concentration by 58% (7.16 ng/ml). The combined ketoprofen and xylazine treatment (13.26 mg/kg, i.p.) decreased the cyclooxygenase-2 by 94% (0.98 ng/ml). The ketoprofen plasma concentration in the combined treatment group was significantly higher compared to the ketoprofen treatment group. Ketoprofen plasma concentrations measured at 0.25, 0.5, 1, 2, 4, and 24 hours were 19.07, 18.94, 14.66, 6.53, 5.44, and 5.54 µg/ml, respectively. Plasma concentrations of ketoprofen and xylazine were raised to 28.74, 29.74, 15.32, 13.04, 14.64, and 11.95 µg/ml or by 51%, 56%, 5%, 100%, 169%, and 116%, respectively. Ketoprofen pharmacokinetic variables were increased (AUC0-∞ (515%), AUMC0-∞ (2389%), MRT (305%), t1/2β (375%), Tmax (100%), and Cmax (55%)), while other values were decreased (Kel (79%), Vss (25%), and Cl (88%)). Our findings suggested a synergistic interaction between ketoprofen and xylazine on the level of cyclooxygenase-2 (pharmacodynamic interaction) which was exerted by modification of the ketoprofen pharmacokinetic properties in mice.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"46 1","pages":"27 - 33"},"PeriodicalIF":0.4,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48545159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Changes in the Lactoferrin Concentration in the Bovine Colostrum During Postpartum Period 产后牛初乳中乳铁蛋白浓度的变化

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-10-01 DOI: 10.2478/macvetrev-2022-0026

B. Trajkovska, Ljupche Kochoski, G. Dimitrovska, Z. Hajrulai-Musliu, Risto Uzunov, V. Petkov, P. Badgujar

{"title":"Changes in the Lactoferrin Concentration in the Bovine Colostrum During Postpartum Period","authors":"B. Trajkovska, Ljupche Kochoski, G. Dimitrovska, Z. Hajrulai-Musliu, Risto Uzunov, V. Petkov, P. Badgujar","doi":"10.2478/macvetrev-2022-0026","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0026","url":null,"abstract":"Abstract The health condition of the mammary gland is highly crucial for obtaining good quality colostrum. The lactoferrin (LF), as an iron-binding protein, plays a key role in the defense mechanisms of the mammary gland due to its’ bacteriostatic properties. The study aimed to investigate the factors affecting the LF concentration in the bovine colostrum milk during the postpartum period, and the effect of somatic cell count (SCC) on the LF concentration and milk composition. The cows were randomly selected at a dairy farm in Pelagonia region. Colostrum samples from 12 cows were collected. Samples were taken at different time intervals after parturition, 1, 6, 12, 24, 48, 72, 96, and 120 h after parturition. Cows in their second parity were found to have higher levels of LF compared to cows in the third and higher parity (p>0.05). Time had a significant effect on the LF concentration (p<0.01), with the highest value recorded 1 h after parturition remaining stable for one hour. LF concentration and SCC in the colostrum showed a weak positive correlation (r=0.40; p<0.01). The highest LF concentration was noticed when SCC was above 800,000 cells/mL. In conclusion, the colostrum LF concentration was significantly affected by the interactions of the two factors, i.e., time after parturition and SCC (p<0.05). Milk composition was affected by elevated SCC. Parity showed no association with LF. The SCC can be used as a reliable means of assessing colostrum quality.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"177 - 185"},"PeriodicalIF":0.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48940350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxic Effects of Sodium Lauryl Sulfate on Antioxidant Defense System and DNA Damage in Fish Primary Hepatocyte Cultures 十二烷基硫酸钠对鱼类原代肝细胞抗氧化防御系统和DNA损伤的毒性作用

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-10-01 DOI: 10.2478/macvetrev-2022-0027

A. Yeltekin, A. Oğuz

{"title":"Toxic Effects of Sodium Lauryl Sulfate on Antioxidant Defense System and DNA Damage in Fish Primary Hepatocyte Cultures","authors":"A. Yeltekin, A. Oğuz","doi":"10.2478/macvetrev-2022-0027","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0027","url":null,"abstract":"Abstract Synthetic detergents which have a major role in environmental pollution accumulate over time and reach levels that harm nature. The surfactants which are abundantly used as cleaning components are discharged into the Van Lake with the sewage water. These chemicals accumulating in the lake may reach a level that could affect the only fish species of the lake, the Van fish. This study aimed to determine the antioxidant levels of Van fish hepatocyte cell culture medium treated with sodium lauryl sulphate (SLS) and to assess the DNA damage. The effect of SLS was assessed by its dose (1x10−5, 1x10-6, 1x10−7 M) and treatment time (24 h, 48 h). Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), and DNA damage (8-OHdG) were determined in the SLS hepatocyte culture. SOD and GSH-Px were higher on 24 h and 48 h compared to the control group. A significant increase was observed in CAT level in the first 24 h, especially in 1x10−6 and 1x10-5 M concentration. At 48 h, it was observed that the CAT level decreased significantly as the concentration increased. It was determined that MDA and 8-OHdG levels increased depending on concentration and time. In conclusion, different concentrations of SLS affected antioxidant levels in the primary hepatocyte culture of Van Fish and were found to cause an increase in the levels of MDA and 8-OHdG.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"169 - 175"},"PeriodicalIF":0.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49535903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Suppression Effects of Excessively Expressed Gene BCL-2 in Cell Lines of Prostate Cancer 过度表达基因BCL-2在前列腺癌细胞系中的抑制作用

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-10-01 DOI: 10.2478/macvetrev-2022-0028

I. Esmerov, B. Atanasov, Aleksandra Angelevska, Radmila Chrcheva, L. Mickov, L. Angelovski, Slavica Josifovska, Nikolaj Markov, N. Adamov

{"title":"Suppression Effects of Excessively Expressed Gene BCL-2 in Cell Lines of Prostate Cancer","authors":"I. Esmerov, B. Atanasov, Aleksandra Angelevska, Radmila Chrcheva, L. Mickov, L. Angelovski, Slavica Josifovska, Nikolaj Markov, N. Adamov","doi":"10.2478/macvetrev-2022-0028","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0028","url":null,"abstract":"Abstract The aim of this study was to construct two plasmid-specific shRNA transcripts of the bcl-2 gene in order to prepare for reverse of cell apoptosis. The plasmid was designed according to a previously published sequence of interfering RNA following an appropriate reference, using appropriate software. By annulling complementary oligonucleotides, double-stranded inserts were formed. Recombinant shRNA-encoding plasmids were constructed by digestion of psiRNA-x7SKGFPzeo plasmid (psiRNA-x7SKGFPzeo, with restrictive endonuclease BbsI electrophoresis in ultra-pure agarose with low melting point (LMP-Agarose). For each of the constructs, a suitable double-stranded insert downstream of x7SK (strong RNA III promoter) with T4 DNA ligase was cloned. The control plasmid psiRNAScr was used directly for transformation. The PC-3 cell lines were transfected with 2 plasmids, psiRNA-Bcl-2 and psiRNAScr to suppress the bcl-2 gene construct. The results have shown that the lowest level of bcl-2 genes was 48 h, and even lower 72 h after the transfer, and the mRNA levels returned to normal in 120 h. An increase in the percentage of cells with spontaneous apoptosis has been observed with successful inhibition of the bcl-2 gene. The induction of apoptosis in transfected cells increased the percentage of necrotic cells proportionally. The percentage of apoptotic cells transfected with psiRNA-bcl-2 plasmid increased proportionally to the increase of hydrogen peroxide concentration. The transfection of the PC-3 cell line from prostate cancer with constructed shRNA plasmid has induced suppression of bcl-2 gene expression versus control Scr plasmid. Suppression of bcl-2 gene expression significantly increased cell sensitivity to apoptosis induction.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"187 - 199"},"PeriodicalIF":0.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47058111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphometric and Histochemical Features of the Harderian Gland in Rabbits with Different Types of Autonomous Regulation 不同自主调节类型家兔哈德氏腺的形态计量学和组织化学特征

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-09-15 DOI: 10.2478/macvetrev-2022-0024

Аndrii Tybinka, M. Zakrevska, O. Shchebentovska

{"title":"Morphometric and Histochemical Features of the Harderian Gland in Rabbits with Different Types of Autonomous Regulation","authors":"Аndrii Tybinka, M. Zakrevska, O. Shchebentovska","doi":"10.2478/macvetrev-2022-0024","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0024","url":null,"abstract":"Abstract The tonus of autonomous centers reflected in the morpho-functional features of the organs in mammals. The study aimed to establish the influence of the autonomous regulation and its’ typological peculiarities on the structural features of the rabbits’ Harderian gland. Clinically healthy male rabbits, four months old, weighing 3.6-3.9 kg, were selected for the research. Based on the study of heart rate variability, three types of autonomous regulation were outlined, according to which three groups of rabbits were formed: ST rabbits (sympathetic dominant regulation), PS rabbits (parasympathetic dominant regulation), and NT rabbits (combined sympathetic and parasympathetic regulation). After euthanasia, the Harderian gland was dissected in all animals. Histological specimens were prepared and a morphometric examination was performed. ST rabbits corresponded to the minimal indicators in the tubular alveoli in both parts of the gland, as well as the maximum indicators of capsule thickness. NT rabbits corresponded to the maximum values of the acini area in the pink lobe, and in the white lobe - the maximal values of the cross-sectional area of the tubular alveoli, its wall area, and the epithelium height. The maximum acini area corresponded to PS rabbits in the white lobe, and in the pink lobe - the maximum indicators of the tubular alveoli cross-sectional area, and epithelial height. The pink and white lobes’ structure of the rabbit’s Harderian gland was affected by the combined tonus of the sympathetic and parasympathetic centers. The findings elucidate the regulatory and trophic effects on the Harderian gland in rabbits.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"157 - 168"},"PeriodicalIF":0.4,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48568791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Use of Probiotic Bacillus megaterium NCH 55 for Treatment of Subclinical Mastitis in Cows – Preliminary Study 益生菌巨型芽孢杆菌NCH 55治疗奶牛亚临床乳腺炎的初步研究

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-09-15 DOI: 10.2478/macvetrev-2022-0023

O. Shkromada, A. Pikhtirova, E. Pecka-Kiełb, O. Skliar, Y. Musiienko

引用次数: 1

Morphological, Morphometric and Radiographic Studies on the Skull of Lesser Mole-Rats (Nannospalax leucodon) 小鼹鼠(Nannospalax leucodon)颅骨的形态学、形态计量学和放射学研究

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-09-15 DOI: 10.2478/macvetrev-2022-0025

Amina Rizvanović, N. Hadžiomerović, P. Bejdić, J. Mulaomerović

引用次数: 0

Assessment of Hematological and Serum Biochemistry Parameters in Dogs with Acute Diarrhea Due to Different Etiologies 不同病因急性腹泻犬血液学和血清生化指标的评价

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-08-10 DOI: 10.2478/macvetrev-2022-0022

E. Gülersoy, Yusuf Emre Ekici

{"title":"Assessment of Hematological and Serum Biochemistry Parameters in Dogs with Acute Diarrhea Due to Different Etiologies","authors":"E. Gülersoy, Yusuf Emre Ekici","doi":"10.2478/macvetrev-2022-0022","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0022","url":null,"abstract":"Abstract Acute diarrhea (AD) has a complex etiology and may lead to life-threatening conditions. Hematological and serum biochemistry analyses can be useful for a differential diagnosis and for determining the severity of diarrhoea. Dogs with AD (n=72) were divided into Isospora (n=18), Toxocara (n=18), Parvoviral Enteritis (n=18), and Dietary Diarrhea (n=18) subgroups following clinical and laboratory examinations. The study aimed to evaluate the diagnostic value of certain hematological and serum biochemistry parameters. Clinical examinations, rapid diagnostic tests, complete blood count (CBC), and biochemical analyses were performed. White blood cell count (WBC), granulocyte, and mean hemoglobin concentration (MCH) levels were lower in the Parvoviral Enteritis Group compared with the other groups (p<0.01). Isospora, Parvoviral Enteritis, and Toxocara groups had lower glucose and total protein, and higher creatinine levels than those of the Control and Dietary Diarrhea groups (p<0.0001). The albumin level of the Dietary Diarrhea Group was higher compared with the other groups (p<0.0001). Parvoviral Enteritis and Isospora groups had higher ALP levels than those of the other groups (p<0.0001). Blood urea nitrogen (BUN), alanine aminotransferase (ALT), C-reactive protein (CRP), and cholesterol levels were determined to be highest in the Parvoviral Enteritis Group (p<0.0001). The total bilirubin level was higher in Parvoviral Enteritis and Toxocara groups compared with the Control, Isospora, and Dietary Diarrhea groups (p<0.0001). As a result, it was concluded that in cases of AD due to parvoviral enteritis and Toxocara canis, serum biochemistry abnormalities may be more severe, can provide more clinical information than CBC, and can be useful in forming a differential diagnosis list, especially in triage.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"149 - 156"},"PeriodicalIF":0.4,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44544149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Carbohydrate Metabolism in Diabetic Rat’s Heart – The Effects of Acetylsalicylic Acid and Heat Preconditioning as HSP70 Inducers 糖尿病大鼠心脏碳水化合物代谢-乙酰水杨酸和热预处理作为HSP70诱导剂的作用

IF 0.4

Macedonian Veterinary Review Pub Date : 2022-08-02 DOI: 10.2478/macvetrev-2022-0021

M. Dervisevik, Suzana Dinevska-Kjovkarovska, S. Panov, Elena Rafailovska, I. Celeska, B. Miova

{"title":"Carbohydrate Metabolism in Diabetic Rat’s Heart – The Effects of Acetylsalicylic Acid and Heat Preconditioning as HSP70 Inducers","authors":"M. Dervisevik, Suzana Dinevska-Kjovkarovska, S. Panov, Elena Rafailovska, I. Celeska, B. Miova","doi":"10.2478/macvetrev-2022-0021","DOIUrl":"https://doi.org/10.2478/macvetrev-2022-0021","url":null,"abstract":"Abstract The myocardium of diabetic subjects displays reduced HSP70 protein level and weak myocardial protection. However, the heart possesses an ability to produce heat shock proteins (HSPs) after exposure to sublethal heat stress. Acetylsalicylicacid (ASA) has the property of pharmacological induction of HSPs. We evaluated the common effects of single dose ASA-pretreatment, prior to heat preconditioning (HP), over carbohydrate metabolism-related enzymes and substrates in the heart of diabetic rats. Streptozotocin-diabetes caused significant decrease of HSP70 protein level, stimulation of the gluconeogenic processes and inhibition of glycolytic processes in the heart. HP-diabetic hearts have significantly higher HSP70 protein level, lower glycogen, glucose-6-phosphate content, glycogen phosphorylase and hexokinase activity, and higher glucose levels and PFK activity. ASA-pretreatment of HP-diabetic animals caused additional increase of HSP70, additional decrease of glycogen, glucose-6-phosphate, glycogen phosphorylase and hexokinase, and additional increase of glucose and PFK in the heart. In conclusion, HP is physiological inducer of HSP70 level in heart and tends to reverse carbohydrate - related disturbances in diabetic rats. ASA, given prior to HP, is a potent HSP70 co-inducer and causes additional increase of HSP70 protein level in heart. ASA, given in a combination to HP, have shown more evident protective effects against subsequent intense of stress.","PeriodicalId":18099,"journal":{"name":"Macedonian Veterinary Review","volume":"45 1","pages":"137 - 148"},"PeriodicalIF":0.4,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44262719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0