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Bone marrow necrosis and hyperinflammation after treatment with inotuzumab ozogamicin for B-cell acute lymphoblastic leukaemia. B 细胞急性淋巴细胞白血病患者接受伊妥珠单抗-奥佐加米星治疗后的骨髓坏死和高炎症反应
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)01826-9
Curtis Marcoux, Pinkesh Thakkar, David M Conrad, Allam A Shawwa, Luke Y C Chen
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引用次数: 0
Populations "woefully unprepared" for climate crisis. 人们对气候危机 "准备不足"。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)02133-0
John Zarocostas
{"title":"Populations \"woefully unprepared\" for climate crisis.","authors":"John Zarocostas","doi":"10.1016/S0140-6736(24)02133-0","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)02133-0","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Offline: Xenotransplantation-a new era beckons. 离线：异种移植--新时代在召唤。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)02130-5
Richard Horton
{"title":"Offline: Xenotransplantation-a new era beckons.","authors":"Richard Horton","doi":"10.1016/S0140-6736(24)02130-5","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)02130-5","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jens Juul Holst: physician-scientist and co-discoverer of GLP-1. Jens Juul Holst：医生科学家，GLP-1 的共同发现者。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)02083-X
Geoff Watts
{"title":"Jens Juul Holst: physician-scientist and co-discoverer of GLP-1.","authors":"Geoff Watts","doi":"10.1016/S0140-6736(24)02083-X","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)02083-X","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Department of Error. 错误部。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 Epub Date: 2024-09-16 DOI: 10.1016/S0140-6736(24)01933-0
{"title":"Department of Error.","authors":"","doi":"10.1016/S0140-6736(24)01933-0","DOIUrl":"10.1016/S0140-6736(24)01933-0","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term ill health in sepsis survivors: an ignored health-care challenge? 败血症幸存者长期健康状况不佳：被忽视的医疗挑战？
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 Epub Date: 2024-09-11 DOI: 10.1016/S0140-6736(24)01754-9
Abi Beane, Manu Shankar-Hari
{"title":"Long-term ill health in sepsis survivors: an ignored health-care challenge?","authors":"Abi Beane, Manu Shankar-Hari","doi":"10.1016/S0140-6736(24)01754-9","DOIUrl":"10.1016/S0140-6736(24)01754-9","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mildred Stahlman. 米尔德里德-斯塔尔曼
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)02085-3
Andrew Green
{"title":"Mildred Stahlman.","authors":"Andrew Green","doi":"10.1016/S0140-6736(24)02085-3","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)02085-3","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physician heal thyself. 医者自医
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)02087-7
Daniel Marchalik, Diane Rehm
{"title":"Physician heal thyself.","authors":"Daniel Marchalik, Diane Rehm","doi":"10.1016/S0140-6736(24)02087-7","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)02087-7","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Lancet Countdown on health and climate change: representation matters - Authors' reply. 柳叶刀》关于健康与气候变化的倒计时：代表性问题--作者的答复。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 DOI: 10.1016/S0140-6736(24)01915-9
Marina Romanello, Paul J Beggs, Wenjia Cai, Georgiana Gordon-Strachan, Stella Hartinger, Kris Murray, Cathryn Tonne
{"title":"The Lancet Countdown on health and climate change: representation matters - Authors' reply.","authors":"Marina Romanello, Paul J Beggs, Wenjia Cai, Georgiana Gordon-Strachan, Stella Hartinger, Kris Murray, Cathryn Tonne","doi":"10.1016/S0140-6736(24)01915-9","DOIUrl":"https://doi.org/10.1016/S0140-6736(24)01915-9","url":null,"abstract":"","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipoprotein(a) and cardiovascular disease. 脂蛋白（a）与心血管疾病。
IF 98.4 1区 医学
Lancet Pub Date : 2024-09-28 Epub Date: 2024-09-12 DOI: 10.1016/S0140-6736(24)01308-4
Børge G Nordestgaard, Anne Langsted
{"title":"Lipoprotein(a) and cardiovascular disease.","authors":"Børge G Nordestgaard, Anne Langsted","doi":"10.1016/S0140-6736(24)01308-4","DOIUrl":"10.1016/S0140-6736(24)01308-4","url":null,"abstract":"<p><p>One in five people are at high risk for atherosclerotic cardiovascular disease and aortic valve stenosis due to high lipoprotein(a). Lipoprotein(a) concentrations are lowest in people from east Asia, Europe, and southeast Asia, intermediate in people from south Asia, the Middle East, and Latin America, and highest in people from Africa. Concentrations are more than 90% genetically determined and 17% higher in post-menopausal women than in men. Individuals at a higher cardiovascular risk should have lipoprotein(a) concentrations measured once in their lifetime to inform those with high concentrations to adhere to a healthy lifestyle and receive medication to lower other cardiovascular risk factors. With no approved drugs to lower lipoprotein(a) concentrations, it is promising that at least five drugs in development lower concentrations by 65-98%, with three currently being tested in large cardiovascular endpoint trials. This Review covers historical perspectives, physiology and pathophysiology, genetic evidence of causality, epidemiology, role in familial hypercholesterolaemia and diabetes, management, screening, diagnosis, measurement, prevention, and future lipoprotein(a)-lowering drugs.</p>","PeriodicalId":18014,"journal":{"name":"Lancet","volume":null,"pages":null},"PeriodicalIF":98.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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