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Obesity and Its Co-Morbidities among School Teachers in Dhaka City 达卡市学校教师肥胖及其合并症
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.65137
Ripon Barua, Imranul Mawa, Rajib Chowdhury, Muhammad Alamgir Mandal
{"title":"Obesity and Its Co-Morbidities among School Teachers in Dhaka City","authors":"Ripon Barua, Imranul Mawa, Rajib Chowdhury, Muhammad Alamgir Mandal","doi":"10.3329/kyamcj.v13i4.65137","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.65137","url":null,"abstract":"Background: Obesity is an important cause for human morbidity and mortality. Objective: This study was aimed to determine the prevalence of obesity and its co-morbidities among school teachers in Dhaka city. Materials and Methods: This cross sectional study was carried out from May 2017 to October of 2017. Total 250 school teachers aged between 25-59 years were enrolled using cluster random sampling technique. Data on socio-demographic profile, co-morbidities, weight, height and blood pressure were recorded. Results: The prevalence of obesity among school teachers was 15.2%. The mean age of the participants was 46.1±8.2 years. Female teachers were more obese compared to male (20% vs 5.9%), this association was statistically significant (p=0.001). Majority obese participants belonging to the age group of 41-59 years with higher prevalence among female compared to male (25.2% vs 5.8%), this was statistically significant (p=0.030). About 53% obese teachers had hypertension (HTN). On the other hand, Pre-HTN was observed more among obese participants (42.1%) compared to overweight (14.8%). About one third of overweight and obese participants were diabetic (30.6% and 34.2% respectively) and dyslipidaemic (21.5% and 23.7% respectively). Conclusion: The prevalence of obesity and its co-morbidities such as HTN, diabetes mellitus (DM), dyslipidaemia etc was high among the study participants. By promoting healthy life style and behaviors can reduce the burden of obesity and its co-morbidities. \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 245-249","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78575331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dangers of Xenobiotics To Health and Ecosystem 外来生物制剂对健康和生态系统的危害
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.64927
A. Moniruddin
{"title":"Dangers of Xenobiotics To Health and Ecosystem","authors":"A. Moniruddin","doi":"10.3329/kyamcj.v13i4.64927","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.64927","url":null,"abstract":"Abstract not available \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 189-191","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78654573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spirulina platensis Attenuates Cold Allodynia and Chemical Allodynia in Streptozotocin induced Diabetic Rats 螺旋藻减轻链脲佐菌素诱导的糖尿病大鼠冷性和化学性异位性疼痛
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.65057
Munmun Ghosh, Satabdi Ghosh, Taskina Ali, Nahida Sultana Nipa, Shuvajit Roy, Fadia Tasnim, Md Bulbul Hossain, Md. Mahbubur Rahman
{"title":"Spirulina platensis Attenuates Cold Allodynia and Chemical Allodynia in Streptozotocin induced Diabetic Rats","authors":"Munmun Ghosh, Satabdi Ghosh, Taskina Ali, Nahida Sultana Nipa, Shuvajit Roy, Fadia Tasnim, Md Bulbul Hossain, Md. Mahbubur Rahman","doi":"10.3329/kyamcj.v13i4.65057","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.65057","url":null,"abstract":"Background: Diabetic neuropathic pain exerts strong as well as negative influence on both survival and quality of life of the patient. This pain is difficult to treat with conventional analgesics. Now a days, different medicinal herbs are highlighted due to their wide range of beneficial application with less side effects. In this regards Spirulina platensis is well known for its wide range of biological activities. Objective: To assess the effects of oral administration of Spirulina platensis on cold allodynia and chemical allodynia in diabetic neuropathic pain in Long Evans rats.Materials and Methods: This study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from March 2017 to February 2019. Twenty four (24) Long Evans rats, having 150 to 200 grams body weight (on the basis of treatments), the rats were divided into Group I (normal saline 5 ml/kg body weight) and Group II (Spirulina platensis 400 mg/kg body weight). All the supplementations were given once daily for consecutive 21 days orally and last doses were given one hour before the pain evaluation tests. Further on the basis of experiments, previously grouped rats were divided into subgroup ‘a’(cold tail immersion test), and ‘b’ (formalin test). Data were expressed as mean±SEM and were statistically analyzed by SPSS (Version 16) using independent sample ‘t’ test to compare mean value between two groups. (p 0.05 was considered as the level of significance).Results: Spirulina platensis showed significantly higher tail flick latency (p 0.001) in cold tail immersion test. S. platensis demonstrated significantly lowered jerking frequency (p 0.001,p 0.01,p 0.001, respectively); the duration of licking (p 0.001,p 0.05,p 0.001, respectively) and the duration of flexing (p 0.001, non-significant 0.01, respectively) in early, inter and late phases of formalin test in compared to those of control. Conclusion: S. platensis attenuates cold allodynia and chemical allodynia diabetic neuropathic pain in rat model.\u0000KYAMC Journal Vol. 13, No. 04, January 2023: 208-213","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83082874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Pregnancy Induced Hypertension on Babies 妊娠高血压对婴儿的影响
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.65085
Sirajum Monira, Mosammat Afroza Jinnat, Md Tafazzal Hossain Khan, M A Salim, Mashura Musharraf
{"title":"Impact of Pregnancy Induced Hypertension on Babies","authors":"Sirajum Monira, Mosammat Afroza Jinnat, Md Tafazzal Hossain Khan, M A Salim, Mashura Musharraf","doi":"10.3329/kyamcj.v13i4.65085","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.65085","url":null,"abstract":"Background: Pregnancy-induced hypertension (PIH) is a relatively common pregnancy disorder that causes variable maternal and fetal problems. This may increase the number of perinatal asphyxia, sepsis, still birth etc. It also has a significant affect on birth weight which is also related to gestational age. Objectives: To observe the impact of pregnancy induced hypertension on their newborn babies and compare the findings with the babies of normotensive mother. Materias and Methods: This case control study was conducted from July 2016 to December 2016. The study group was selected from the babies of pregnancy induced hypertension (PIH) mothers and control group selected from babies of a normotensive mother attending in Obstetrics department of Dhaka Medical College Hospital, Dhaka having the inclusion and exclusion criteria. The total number of 100 neonates were included consecutively in this study. 50 neonates born to mothers with pregnancy-induced hypertension were grouped as cases and 50 neonates born to normotensive mothers were grouped as control. Results: The study revealed that, the highest frequency of neonatal morbidities were perinatal asphyxia (22%) among the babies of PIH mother. Stillbirth it was found 12 % . The duration of pregnancy were also affected by PIH where most of the babies were preterm (88%) and complete-term pregnancy found only (12%). It should be mentioned that those mother having history of preeclampsia delivered more premature babies (p <0.001). Another important outcome birth weight related to gestational age was also very important which were measured as the highest for SGA 92% and AGA 8%. The weight of the baby were significantly (p<0.001) reduced in those who had a history of PIH and the mean weight was 1592.78 ± 470.06. Conclusion: Prematurity, Small for gestational-age babies and perinatal asphyxia are more common in Pregnancy induced hypertension group than in the normotensive group. \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 204-207","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87136165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stress and Coping Status Among the Caregivers of Psychiatrist Patients 精神科病人照护者的压力与应对状况
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.65104
Mohammad Sayeed Ahmad, Md Abdullah Al Mamun, Sadia Chowdhury, Md Ahsan Habib
{"title":"Stress and Coping Status Among the Caregivers of Psychiatrist Patients","authors":"Mohammad Sayeed Ahmad, Md Abdullah Al Mamun, Sadia Chowdhury, Md Ahsan Habib","doi":"10.3329/kyamcj.v13i4.65104","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.65104","url":null,"abstract":"Background: Mental disorder account for 13% global burden of disease which has affected more than 970 million people worldwide in 2017. About 1 in 17 suffers from serious mental illness in worldwide. Therefore, the affected person is dependent on caregiver and their wellbeing is directly related to nature and quality of care provided by caregiver. Caregiver are especially vulnerable as they face complex, high burden care situation resulting in higher caregiver stress. The aim of this study is to determine the level of stress and coping of caregivers of Psychiatric patients. Materials and Methods: This cross sectional study was conducted among 171 caregivers, aged more than 18 years in National Institute of Mental Health (NIMH) Shyamoli, Dhaka. Study period was from 1 January to 31 December 2020. The research participants were selected following the convenient sampling method based on defined selection criteria. A semi-structured questionnaire was developed and the respondents were interviewed face to face individually while maintaining privacy and confidentiality. Result: Distribution of the socio demographic status of the study participants were females74% and male 26%. Their mean age was 40.09(±13.31) years. In educational level 33.9 % of the participants were illiterate, secondary level education up to 21.1%. In occupation housewife 57.9%, service holder 18.7%. Caregiver having 76.6% moderate stress, low stress 21.6% and 1.8% having high perceived stress. Association between stress and coping average, good coping 74.8% and 88.2% had moderate stress respectively. Their significant P value .009(p<0,05). The person’s correlation present between stress and coping was positive. The correlation co-efficient was .06 (p<0.05). So, there was a weak positive correlation between level of stress and coping status. Conclusion: Health care personal may screen the stress level of caregivers and if there is any functional impairment is present, they could proper evaluation and therapeutic intervention. \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 240-244","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77093089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep Quality among Undergraduate Public Medical and University Students: A Comparative Study 公立医学院本科生与普通高校学生睡眠质量的比较研究
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.64857
Md Golam Abbas, Somaya Mostarin, Sumaya Hossin Rimmi, Riazin Sultana, Showlin Hossain, Mohammad Nurunnabi
{"title":"Sleep Quality among Undergraduate Public Medical and University Students: A Comparative Study","authors":"Md Golam Abbas, Somaya Mostarin, Sumaya Hossin Rimmi, Riazin Sultana, Showlin Hossain, Mohammad Nurunnabi","doi":"10.3329/kyamcj.v13i4.64857","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.64857","url":null,"abstract":"Background: Sleeping is the body's natural means of recharging, which aids in repair, healing, and learning from all interactions and activities during the day. To maintain their focus, concentration, and academic performance, students need to get enough sleep at night. Objective: To determine and compare the sleep quality of 278 undergraduate medical and university students. Materials and Methods: This online-based cross-sectional study was conducted by using a pre-tested semi-structured questionnaire with Pittsburgh Sleep Quality Index (PSQI) scale. Results: The mean age of medical students were 22.6±1.5 years and university students were 22.0±1.2 years. The mean study hours in a day, spending time on digital media and BMI were almost similar in both settings students. The mean PSQI scores were 7.2±3.3 in medical students and 6.4±3.3 in university students respectively. Majorities of the students (71.2% and 58.3%) had poor sleep quality, but subjective sleep quality was good in both settings of students (60.4% and 51.8%). Educational backgrounds were significantly associated with level of sleep quality, level of subjective sleep quality and mean of PSQI scores (p<0.05). Conclusion: This study demonstrates that sleep quality is poor among public medical college students compared to university students. \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 223-228","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83055594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compare the Effect of Zinc–Probiotic versus Zinc Therapy in Acute Watery Diarrhea in Children 锌-益生菌与锌治疗儿童急性水样腹泻的疗效比较
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.64890
Rumy Tabrez Hyder, Shafi Ahmed, ATM Faruque Ahmed
{"title":"Compare the Effect of Zinc–Probiotic versus Zinc Therapy in Acute Watery Diarrhea in Children","authors":"Rumy Tabrez Hyder, Shafi Ahmed, ATM Faruque Ahmed","doi":"10.3329/kyamcj.v13i4.64890","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.64890","url":null,"abstract":"Background: Acute watery diarrhea still remains a major health problem among under 5 children worldwide. Apart from oral rehydration solution, continued feeding and oral zinc therapy the administration of adequate amounts of probiotics seems beneficial for acute diarrheal episodes in children in the developing world. Objective: To compare the efficacy of zinc-probiotic combination therapy versus zinc-only therapy in children with acute watery diarrhea. Materials and Methods: This was a hospital based randomized controlled clinical trial (RCT) conducted from July 2019 to June 2021 in the Department of Pediatrics, Khwaja Yunus Ali Medical College & Hospital. Total 70 children aged 6 months to 5 years admitted in hospital with acute watery diarrhea (AWD) with severe dehydration or some dehydration with intractable vomiting were included in this study. Patients were equally divided into 2 groups. Group A received oral zinc sulfate 20 mg/day for 10 days combined with oral Bacillus clausii probiotic 4million spores/day for 5 days. Group B received only oral zinc sulfate at the same dosage as group A. We also studied the relationship between mother`s education, knowledge of ORS preparation and child’s feeding practices and nutritional status with the occurrence of diarrhea in children. Results: Frequency of diarrhoea was significantly higher in group B (Zinc only) in comparison to group A (Zinc and probiotic). Mean frequency of diarrhea, Mean duration of diarrhea and Mean length of hospital stay was significantly higher in group B (Zinc) than group A (Zinc+Probiotic). Conclusion: Compared to oral Zinc therapy only; the combination of oral zinc and probiotic therapy is clinically more effective in reducing the frequency of acute watery diarrhea in under 5 years children.\u0000KYAMC Journal Vol. 13, No. 04, January 2023: 218-222","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88959032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between Effects of Fentanyl and Fenofol as Sedative in Elective Caesarean Section under Subarachnoid Anaesthesia 芬太尼与非诺酚在选择性剖宫产蛛网膜下腔麻醉中的镇静效果比较
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.40949
Md Enayet Karim, Mohammad Saleh Akram, RAM Mustafijur Rashid, Reza Ershad, Md Muzibur Rahman
{"title":"Comparison between Effects of Fentanyl and Fenofol as Sedative in Elective Caesarean Section under Subarachnoid Anaesthesia","authors":"Md Enayet Karim, Mohammad Saleh Akram, RAM Mustafijur Rashid, Reza Ershad, Md Muzibur Rahman","doi":"10.3329/kyamcj.v13i4.40949","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.40949","url":null,"abstract":"Background: Regional anaesthesia has become an important anaesthetic technique now a days. Pharmacologically induced tranquility improves acceptance of regional technique. Objective: To compare Fentanyl and Fenofol (Fentanyl+Propofol) in terms of onset and recovery of sedation, haemodynamic effects, respiratory effects and adverse effects of both the drugs during elective Caesarian section under spinal(subarachnoid) anaesthesia. Materials and Methods: This randomized clinical trial included 60 ASA (American Society of Anaesthesiologists) grade I or II patients between age 20-40 years undergoing elective Caesarean sections under Subarachnoid anaesthesia during the period January 2022 to June 2022. Patients were randomly allocated to one of two groups: Fentanyl group (Group F, n=30), who received Fentanyl in a single dose of 0.5mcg/kg and Fenofol group (Group FP, n=30), who received Fenofol in a single dose of Fentanyl-0.5mcg/kg+Propofol-0.5mg/kg. Spinal anaesthesia was conducted by injecting a hyperbaric solution of 0.5% bupivacaine 3ml through a 25G spinal needle at L3-4 level. All parameters were documented at 5 min intervals until arousal of the patient. The onset of sedation i.e. time from iv (intravenous) injection of Fentanyl or Fenofol to closure of eye lids (OAA/S score of 3) and the arousal time from sedation i.e. time from closing of the eye lids to OAA/S score of 5 ( patient is awake clinically) were noted. Any complication during operation was documented. The patient’s satisfaction with the sedation was assessed by the 5 point ‘Likert verbal rating scale.’ Results: There was no significant difference of mean blood pressure and mean heart rate between the two groups in different time intervals (P>0.05). Time of onset of sedation and the arousal time i.e. duration of sedation was comparable between the two groups (P>0.05). Significant percentage of patients required O2 supplementation in Fenofol group due to hypoventilation (66.66% vs 10%, P<0.001). Pain in arm during drug administration was significantly more with Fenofol (46.66% vs 6.66%, P<0.001). Conclusion: As a significantly higher percentage of patients required O2 supplementation during sedation with Fenofol and pain in arm during drug administration was significantly more in Fenofol group, it is recommended that Fentanyl is a better choice than Fenofol for sedation in single dose technique during subarachnoid block for Caesarean section.\u0000KYAMC Journal Vol. 13, No. 04, January 2023: 234-239","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74732654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Kidney Injury Is A Predictor Of Mortality In Patients Hospitalized With Covid-19 急性肾损伤是Covid-19住院患者死亡率的预测因子
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.65031
Md Maqsudur Rasul, Emran Hossain, Miskat Joha, Dewan Mohaimenul Haque
{"title":"Acute Kidney Injury Is A Predictor Of Mortality In Patients Hospitalized With Covid-19","authors":"Md Maqsudur Rasul, Emran Hossain, Miskat Joha, Dewan Mohaimenul Haque","doi":"10.3329/kyamcj.v13i4.65031","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.65031","url":null,"abstract":"Background: Common biomarkers used to determine the disease severity and prognosis of corona virus disease -19 (Covid-19) are well determined. Among these biomarkers only few can reliably predict disease outcome but they are not easily available and costly. So organ-specific functional status especially acute kidney injury (AKI) can be use as predictor of prognosis. Objective: To determine the kidney disease indicator as a marker in predicting the severe disease in COVID-19 patients. Material & Methods: We studied the health records for all purposively selected hospitalized Covid-19 patients for three months from 1st May to 31st July, 2020, at combined military hospital Dhaka, Bangladesh. Those who were more than 18 years old and hospitalized RT-PCR positive for COVID-19 patients were enrolled. Those having history of renal replacement therapy (RRT) and unwilling to participate were excluded from the study. Kidney disease significance between survivors and deceased were examined using Cox proportional hazard regression analysis. In-hospital death was ascertained by using the Kaplan-Meier method.Results: Total 470 patients were enrolled in this study. Mean age of study population was 54.7 (± 14.3) years and male to female ratio was about 2:1. Hypertension (51.91%) and diabetes mellitus (43.19%) were the most common co morbidity. During hospital stay 106 (22.55%) patients developed AKI. Total 23 (4.89%) patients were died of the total study population. Among them 19 (82.60%) had AKI. Mortality rate was significantly (P value<.001) higher among patients who developed AKI than those who did not (82.60 % vs 17.40%).Conclusion: Monitoring functional status of kidney should be given due importance to all Covid-19 patients even with mild disease. Early diagnosis and appropriate treatment of kidney injury and avoidance of nephrotoxic medications may help to reduce mortality and improve prognosis of COVID-19. \u0000KYAMC Journal Vol. 13, No. 04, January 2023: 192-197","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74854407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcome after Downstaging in Locally Advanced Breast Carcinoma-A Clinical Study of 50 Cases 局部晚期乳腺癌降分期后的手术效果——附50例临床分析
KYAMC Journal Pub Date : 2023-03-30 DOI: 10.3329/kyamcj.v13i4.63191
Shaikh Adnan Rakib, S. B. Sharif, Morsalin Rahman, F. Islam, Kazi Shaila Najnin
{"title":"Surgical Outcome after Downstaging in Locally Advanced Breast Carcinoma-A Clinical Study of 50 Cases","authors":"Shaikh Adnan Rakib, S. B. Sharif, Morsalin Rahman, F. Islam, Kazi Shaila Najnin","doi":"10.3329/kyamcj.v13i4.63191","DOIUrl":"https://doi.org/10.3329/kyamcj.v13i4.63191","url":null,"abstract":"Background: The number of deaths related to breast cancer is increasing at an alarming pace worldwide. In Bangladesh, the incidence rate of breast cancer was about 22.5 per 100000 females. Almost everyone has a palpable lump, and 40% of them have locally advanced breast cancer. The typical treatment for patients with LABC is neoadjuvant chemotherapy followed by surgery.\u0000Materials and Methods: From January 2018 to December 2022, 50 newly diagnosed locally advanced breast cancer (LABC) patients were enrolled in this prospective study at the Bangladesh Medical College Hospital, Dhaka; to assess the clinical and pathological response of the disease after chemotherapy and surgery. The size of the primary tumor and the size of the axillary nodes were measured and compared to the previous record. The patients had a surgery and axillary excision after three to six weeks of neoadjuvant treatment. The pathological response of the primary tumor and axillary node was examined using histopathology. Other biological markers were tested, including the estrogen receptor (ER), progesterone receptor (PR) and Human epidermal growth factor receptor (Her-2).\u0000Results: 44 patients (88.0%) responded clinically after four cycles of neoadjuvant chemotherapy, with 7 patients (14.0%) showing complete clinical response (cCR) and 41 patients (82.0%) showing partial response (pCR). In 22 individuals, surgical specimens revealed complete pathological response (cPR) (10 percent).\u0000Conclusions: The neoadjuvant chemotherapy schedule for locally advanced breast cancer has good surgical outcome.\u0000KYAMC Journal Vol. 13, No. 04, January 2023: 229-233","PeriodicalId":17948,"journal":{"name":"KYAMC Journal","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80868084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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