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D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS最新文献

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Novel Non-Catalytic FAK Inhibition Downregulates Lung Fibroblast Matrix Production 新型非催化性FAK抑制下调肺成纤维细胞基质生成
D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5249
Y. Moreno Caro, W. Weiner, L. Naser, W.G. Grischo, M. Kala, L. Hecker, T. Wang, K. Knox, T. Marlowe
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引用次数: 0
Delivery of Soluble Klotho cDNA to the Lung Alleviates Acute Lung Injury 可溶性Klotho cDNA的肺传递减轻急性肺损伤
D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253
J. Gagan, D. M. Dane, C. Hsia
{"title":"Delivery of Soluble Klotho cDNA to the Lung Alleviates Acute Lung Injury","authors":"J. Gagan, D. M. Dane, C. Hsia","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5253","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125151433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Dynamic Contrast Enhancement Computed Tomography Analysis Models to Characterize Pulmonary Blood Flow in a Pig Model of ARDS 动态增强计算机断层扫描分析模型对ARDS猪模型肺血流特征的比较
D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255
T. Kim, Y. Xin, K. Martin, H. Song, A. Lenart, S. Gerard, M. Petrov, J. Shen, K. Rozenberg, J. Herrmann, L. Staelin, S. Humayun, P. Shah, U. Sidhu, S. Bathula, K. Reutlinger, M. Staley, P. Delvecchio, J. Barakat, S. Sarfaraz-Khan, I. Duncan, L. Berra, R. Rizi, M. Cereda
{"title":"Comparison of Dynamic Contrast Enhancement Computed Tomography Analysis Models to Characterize Pulmonary Blood Flow in a Pig Model of ARDS","authors":"T. Kim, Y. Xin, K. Martin, H. Song, A. Lenart, S. Gerard, M. Petrov, J. Shen, K. Rozenberg, J. Herrmann, L. Staelin, S. Humayun, P. Shah, U. Sidhu, S. Bathula, K. Reutlinger, M. Staley, P. Delvecchio, J. Barakat, S. Sarfaraz-Khan, I. Duncan, L. Berra, R. Rizi, M. Cereda","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5255","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127743488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D Fibrotic Lung Extracellular Matrix Hydrogels Trigger Pro-Fibrotic Responses in Primary Lung Fibroblasts 3D纤维化肺细胞外基质水凝胶触发原代肺成纤维细胞的促纤维化反应
D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245
M. Nizamoglu, T. Koster, M. Thomas, W. Timens, C. Koss, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess
{"title":"3D Fibrotic Lung Extracellular Matrix Hydrogels Trigger Pro-Fibrotic Responses in Primary Lung Fibroblasts","authors":"M. Nizamoglu, T. Koster, M. Thomas, W. Timens, C. Koss, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5245","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115784392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PLN-74809, an Oral, Dual-Selective αvβ6/αvβ1 Inhibitor in Phase 2 Clinical Trials for Idiopathic Pulmonary Fibrosis (IPF), Sustainably Reduces Transforming Growth Factor Beta (TGF-β) Activity in the Lungs of Healthy Participants with Once-Daily Dosing PLN-74809是一种口服双选择性αvβ6/αvβ1抑制剂，在治疗特发性肺纤维化(IPF)的2期临床试验中，每日一次给药可持续降低健康受试者肺部转化生长因子β (TGF-β)活性
D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251
G. Cosgrove, M. Decaris, S. Wong, E. Park, S. Turner, E. Adegbite, E. Lefebvre
{"title":"PLN-74809, an Oral, Dual-Selective αvβ6/αvβ1 Inhibitor in Phase 2 Clinical Trials for Idiopathic Pulmonary Fibrosis (IPF), Sustainably Reduces Transforming Growth Factor Beta (TGF-β) Activity in the Lungs of Healthy Participants with Once-Daily Dosing","authors":"G. Cosgrove, M. Decaris, S. Wong, E. Park, S. Turner, E. Adegbite, E. Lefebvre","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5251","url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131727518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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