IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)最新文献

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Multivariate statistical analysis for dermatological disease diagnosis 皮肤病诊断的多变量统计分析
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864412
A. S. Barreto
{"title":"Multivariate statistical analysis for dermatological disease diagnosis","authors":"A. S. Barreto","doi":"10.1109/BHI.2014.6864412","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864412","url":null,"abstract":"The differential diagnosis of some erythemato-squamous diseases is a major problem in dermatology. This is the case with: psoriasis, seborrhoeic dermatitis, lichen planus, pityriasis rosea, chronic dermatitis, and pityriasis rubra pilaris. Further complicating diagnosis, they all share clinical features, with very few differences. Although biopsies could help physicians, these diseases also share many histopathological features. In this context, this research applies a multivariate statistical analysis to explore the Dermatology Data Set (available in the UCI data repository) and construct a classifier, based on the clinical features, as an aid to the medical diagnosis of erythemato-squamous dermatological diseases. The research results provide enhanced knowledge that can help to enrich dermatological diagnoses made by doctors. Also, the classifier developed using the Linear Discriminant Analysis obtains a high mean accuracy rate in relation to the 6 diseases (83.73% correct classifications). This rate means that patients have a strong chance of being treated adequately, while biopsies may also be solicited.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130983119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Fractal and image analysis of cytoskeletal changes in tumour cells due to the effects of maspin 肿瘤细胞因maspin作用而发生的细胞骨架变化的分形和图像分析
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864341
Mohammad A Al-Mamun, Lorna Ravenhill, Mohammed Alamgir Hossain, D. M. Farid, R. Bass
{"title":"Fractal and image analysis of cytoskeletal changes in tumour cells due to the effects of maspin","authors":"Mohammad A Al-Mamun, Lorna Ravenhill, Mohammed Alamgir Hossain, D. M. Farid, R. Bass","doi":"10.1109/BHI.2014.6864341","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864341","url":null,"abstract":"Maspin (SERPINB5) is a type II metastasis suppressor that influences multiple cellular functions. To date, maspin has been shown to increase adhesion and apoptosis and to decrease cell migration, proliferation, invasion and metastases in tumour malignancy. At the subcellular level, maspin influences morphological changes in the cell cytoskeleton which regulates complex biological processes including cell migration, cell adhesion and EMT (epithelial to mesenchymal transition). Here non-Euclidian fractal and image analyses have been applied to measure changes in the actin cytoskeleton using confocal microscopy images to confirm the effects of maspin. Results show that maspin contributes to maintaining the regular epithelial like shape, increases cell-cell adhesion and restricts tumour cells from showing the pre-migration and EMT characteristics. Characterization of these changes in the actin cytoskeleton using microscopic image analysis will establish maspin as a potential prognostic marker in future.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"211 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133801098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Colibri project: A multicenter shared database of magnetic resonance images about rare neurological diseases Colibri项目:一个关于罕见神经疾病的磁共振图像的多中心共享数据库
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864387
C. Altomare, G. Lanzola, R. Bellazzi, G. Reni
{"title":"The Colibri project: A multicenter shared database of magnetic resonance images about rare neurological diseases","authors":"C. Altomare, G. Lanzola, R. Bellazzi, G. Reni","doi":"10.1109/BHI.2014.6864387","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864387","url":null,"abstract":"Rare diseases occur infrequently or rarely in a population and among them, nearly 75% affect children. To date, their low prevalence and heterogeneity resulted in a lack of scientific knowledge and prevented an access to a quick and correct diagnosis. The sharing of multiple sources of information from different centers and actors may have a key role in this field. In order to address this issue, a network of Italian centers of excellence in pediatric neuroradiology launched the Colibri project with the aim to collect, share and process data about rare disease patients. The goal is to constitute a large dataset including Magnetic Resonance images and other clinical data of pediatric subjects in order to provide a service for the research and the consultation. The dataset will be made available through an architecture whose components are compliant with the DICOM Standard and will encompass a security mechanism to ensure subject privacy.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134186040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A web-tool to manage ophthalmologic electronic health records 管理眼科电子健康记录的网络工具
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864374
Monica Bonetto, P. Fraccaro, M. Nicolò, M. Giacomini
{"title":"A web-tool to manage ophthalmologic electronic health records","authors":"Monica Bonetto, P. Fraccaro, M. Nicolò, M. Giacomini","doi":"10.1109/BHI.2014.6864374","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864374","url":null,"abstract":"The solution described in this paper is a web tool to access and manage patients' data in Ophthalmology. Clinical data are collected in a database through a system that can be easily utilized by physicians and internal information can be extracted for statistical purposes. The platform is also available for simultaneous Multicenter Clinical Trials. A specific algorithm and extraction tool were developed to allow physicians to extract data for research purposes. Users can simply add and manage patients, records, follow-up visits, treatments, diagnosis, clinical history; all the information can be modified and reused whenever required. Physicians can also enter specific extraction criteria, in order to exploit the full potential of the available information. Once the extraction of data is completed, it is possible to view and save data in an Excel format. The Ophthalmology Clinic of the San Martino Hospital in Genoa has been working with this web tool since April 2013. By the end of November 2013, 568 patients and 2668 visits had been registered. The web-platform allows effective management, sharing and reuse of information within primary care and clinical research. In the near future, there is a plan to share the system with other Italian centers.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134457044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Monitoring physical activity and energy expenditure with smartphones 用智能手机监测身体活动和能量消耗
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864451
Bruno Aguiar, Joana Silva, Tiago Rocha, S. Carneiro, I. Sousa
{"title":"Monitoring physical activity and energy expenditure with smartphones","authors":"Bruno Aguiar, Joana Silva, Tiago Rocha, S. Carneiro, I. Sousa","doi":"10.1109/BHI.2014.6864451","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864451","url":null,"abstract":"Monitoring physical activity and energy expenditure is important for maintaining adequate activity levels with an impact in health and well-being. This paper presents a smartphone based method for classification of inactive postures and physical activities including the calculation of energy expenditure. The implemented solution considers two different positions for the smartphone, the user's pocket or belt. The signal from the accelerometer embedded in the smartphone is used to classify the activities resorting to a decision tree classifier. The average accuracy of the classification task for all activities is 99.5% for the pocket usage and 99.4% when the phone is used in the belt. Using the output of the activity classifier we also compute an estimation of the energy expended by the user. The proposed solution is a trustworthy smartphone based activity monitor, classifying the activities of daily living throughout the entire day and allowing to assess the associated energy expenditure without causing any change in user's routines.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131349362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Detection of artifacts in oscillometric pulsations signals 振荡脉冲信号中伪影的检测
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864462
J. Havlík, Zuzana Martinovska, J. Dvořák, L. Lhotská
{"title":"Detection of artifacts in oscillometric pulsations signals","authors":"J. Havlík, Zuzana Martinovska, J. Dvořák, L. Lhotská","doi":"10.1109/BHI.2014.6864462","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864462","url":null,"abstract":"A measurement of blood pressure is a basic diagnostic technique for examining of the cardiovascular system. There are a lot of methods for determination of the blood pressure, but an oscillometric measurement (investigation of oscillometric pulsations) is one of the most frequent methods used in modern electronic tonometers. The results given by oscillometric measurements are very dependent on the cleanness of the signal. The method is very sensitive for example for motion artifacts, which produce significant damage of the signal. For the proper processing of the signal it is very important to detect all artifacts precisely before signal processing. The paper deals with the methods for artifacts detection in oscillometric pulsations signals. The methods based on predicted heart rate detection, heart rate variability (standard deviation method) and comparison of oscillometric pulsations with ECG signal are described in the paper. The section Results includes a comparison of the methods and a discussion of their advantages and disadvantages. The authors conclude that the algorithm based on detection of heart rate variability (standard deviation method) seems as the most suitable algorithm for automated detection of artifacts in the signal of oscillometric pulsations.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114837087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Verification of effectiveness on position correction system using HRV analysis with obstructive sleep apnea 利用HRV分析阻塞性睡眠呼吸暂停患者位置校正系统的有效性验证
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864470
B. Choi, S. Ye, S. Park, Sung Min Kim
{"title":"Verification of effectiveness on position correction system using HRV analysis with obstructive sleep apnea","authors":"B. Choi, S. Ye, S. Park, Sung Min Kim","doi":"10.1109/BHI.2014.6864470","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864470","url":null,"abstract":"Obstructive sleep apnea (OSA) is a sufficiently common disease that may negatively affect high-quality sleeping. Reduction in muscle strain of body and laxity in the respiratory tract during sleeping can cause apnea in sleep period. OSA decreases blood oxygen saturation and increases effort to breathe to cause arousal via reaction of neurologic mechanisms, indicating that it induces autonomic imbalance by enhancing activities in the sympathetic nervous system. In this context, the purpose of this paper is to identify freeing airways via changing positions during sleeping in order to alleviate causes of airway blockage by muscular laxity while sleeping. The authors caused changes in sleeping positions and airway blockage while sleeping, analyzing the time and the frequency domains of the Heart rate variability (HRV) signals. Among the parameters used in this study, there were statistically significant differences in OSA section and the transformation of those parameters in the standard deviation of NN interval (SDNN) of the time domain and the NLF, the NHF, and the low frequency (LF)/high frequency (HF) of the frequency domain. In conclusion, sleep apnea symptoms may be alleviated via changing positions during sleep apnea.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131770360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-time apnea detection using pressure sensor and tri-axial accelerometer 利用压力传感器和三轴加速度计进行实时呼吸暂停检测
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864415
P. Pierleoni, Luca Pernini, Alberto Belli, Lorenzo Palma
{"title":"Real-time apnea detection using pressure sensor and tri-axial accelerometer","authors":"P. Pierleoni, Luca Pernini, Alberto Belli, Lorenzo Palma","doi":"10.1109/BHI.2014.6864415","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864415","url":null,"abstract":"Respiratory disorders, if diagnosed late and untreated, may cause the advancement of many pathologies especially pertaining the cardiovascular system. This study proposes a method for a fast and certain detection of apnea events. For this purpose we used a commercial device that contains a pressure sensor helpful for the measurement of breath and a tri-axial accelerometer necessary to improve the detection reliability. There are numerous commercial devices able to detect breathing, but the totality of them is oriented to sport activity monitoring and so calibrated on the upper thresholds of respiratory rate. These devices are therefore not directly used as biomedical devices specific for the detection of sleep apneas or as life-saving devices in the case of “voluntary” apneas that occur in patients with severe neurological or pathological disorders. Then, we have developed complex algorithms to process the signals in real-time for the detection of apnea events with a maximum delay of 10 s, a sensitivity of 99%, and a specificity of 100%. This paper shows how an inexpensive approach is possible to control dependably the occurrence of apneas, avoiding hospitalization and the use of complex, invasive, and expensive devices.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134390235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Using semantic web technologies for quality measure phenotyping algorithm representation and automatic execution on EHR data 利用语义网技术对电子病历数据进行质量测量、表现型算法表示和自动执行
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864419
F. Shen, Dingcheng Li, Hongfang Liu, Yugyung Lee, Jyotishman Pathak, C. Chute, C. Tao
{"title":"Using semantic web technologies for quality measure phenotyping algorithm representation and automatic execution on EHR data","authors":"F. Shen, Dingcheng Li, Hongfang Liu, Yugyung Lee, Jyotishman Pathak, C. Chute, C. Tao","doi":"10.1109/BHI.2014.6864419","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864419","url":null,"abstract":"In this paper, we introduce our efforts on an application of semantic web technologies to phenotyping algorithms in Electronic Health Records (EHR) data for the purpose of facilitating the reasoning and inferring processes of some patients groups in an intelligent manner.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134550782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Designing interactive health care systems: Bridging the gap between patients and health care professionals 设计互动式卫生保健系统:弥合病人和卫生保健专业人员之间的差距
IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) Pub Date : 2014-06-01 DOI: 10.1109/BHI.2014.6864347
L. Graham, Mohammad Moshirpour, Michael R. Smith, B. Far
{"title":"Designing interactive health care systems: Bridging the gap between patients and health care professionals","authors":"L. Graham, Mohammad Moshirpour, Michael R. Smith, B. Far","doi":"10.1109/BHI.2014.6864347","DOIUrl":"https://doi.org/10.1109/BHI.2014.6864347","url":null,"abstract":"As patients become more proactive about their health and turn to technologies such as the Internet to acquire knowledge, the patient-health care professional relationship has been changing. Traditionally, information has flowed from health care professional to patient, but change to a two-way dialogue is taking place. In this study, we examine a high level design of a perceived medical system and determine the implications of adding patients as active contributors. The main challenge of modifying existing systems to incorporate patient interaction is preserving system integrity. We propose a systematic approach to support scaling health care systems while preserving system integrity. Distributed systems such as personal health records and eHealth systems provide two ways in which patients can become more involved with their own health care with or without the involvement of health care professionals. It is important that modifications to such systems do not compromise patient record integrity regardless of whether the patient is working alone or with their health care professional. The lack of central control in distributed systems added to the complexity of health systems poses challenges for design and modification. Of particular interest is the identification of emergent behavior (behavior not explicitly specified in the specifications) in distributed systems not explicitly defined in the requirements of its individual components. Use of the new emergent behavior detection (EBD) tool offers potentially considerable cost savings by proactively identifying such behaviors during the design rather than the deployment phase of a project. Based on high level message sequence charts, the EBD tool highlighted a data synchronization issue between the main database and the patient's interface to the system. This provides valuable feedback of the early health system design which benefits future design development.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133309251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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