JSLS : Journal of the Society of Laparoendoscopic Surgeons最新文献

{"title":"Inflammatory Reaction and Formation of Adhesions after Intraperitoneal Application of Biological SIS Mesh.","authors":"Samir Delibegovic, Enes Idrizovic, Muhamed Katica, Jasminka Mustedanagic, Elmir Cickusic, Aida Katica, Haris Kuralic","doi":"10.4293/JSLS.2025.00059","DOIUrl":"10.4293/JSLS.2025.00059","url":null,"abstract":"<p><strong>Background: </strong>Biological mesh derived from porcine small intestinal submucosa (SIS) has a higher porosity and is more hydrophilic than tissue derived from bovine and cow dermal tissues. Therefore, we believe SIS mesh will lead to a milder inflammatory reaction than other, polypropylene and polypropylene-polydioxanone meshes, fewer adhesions, and less mesh shrinkage.</p><p><strong>Methods: </strong>Ninety rats were divided randomly into three groups: in group 1, polypropylene mesh was implanted; in group 2, polypropylene-polydioxanone; and in group 3, the SIS mesh. The meshes were fixed intra-abdominally, in the upper part of the abdomen. Ten animals from each group were sacrificed on days 7, 28, and 60 after the implantation. Relaparotomy was performed, with a left paramedial incision and the adhesions formed were assessed according to the Surgical Membrane Study Group (SMSG) score, along with the percentage of shrinkage of the mesh, and any inflammation.</p><p><strong>Results: </strong>There were no differences in terms of inflammatory reaction or the formation of adhesions between the meshes tested on the 7th day after implantation. However, the shrinkage of the SIS mesh was more expressed. On days 28 and 60, the SIS mesh caused less inflammatory reaction and formation of adhesions in relation to the other meshes tested. On day 60, there was no significant difference in the size of the meshes.</p><p><strong>Conclusion: </strong>This study confirmed that, despite conflicting views on biological mesh, SIS mesh results in less inflammatory reaction, less adhesion formation, and a lesser degree of shrinkage, and can take its place in hernia repair.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence on \"Assessing Immersive Virtual Reality as Learning Tool for Surgical Trainees\".","authors":"Daungsupawong Hinpetch, Wiwanitkit Viroj","doi":"10.4293/JSLS.2025.00051","DOIUrl":"10.4293/JSLS.2025.00051","url":null,"abstract":"","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Trio of Atypical Ectopic Pregnancies.","authors":"Bruce Lee, Emery M Salom, Alexa Marie Del Mazo","doi":"10.4293/JSLS.2025.00072","DOIUrl":"10.4293/JSLS.2025.00072","url":null,"abstract":"<p><p>Three cases of atypical ectopic pregnancies requiring surgical evaluation are presented. The first case represents an undiagnosed heterotopic pregnancy who initially presented with a 1^st trimester spontaneous abortion and subsequently a ruptured ectopic pregnancy. The second case represents an omental ectopic pregnancy vs an extruded tubal ectopic pregnancy following a salpingectomy requiring omentectomy and appendectomy. The third case showcases a chronic cornual ectopic pregnancy incidentally found during a robotic myomectomy. These cases highlight uncommon presentations of atypical ectopic pregnancies, diagnostic challenges, and surgical treatment.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Pressure-Controlled Volume-Guaranteed Ventilation on Pulmonary Function in Coal Workers with Pneumoconiosis Undergoing Laparoscopic Cholecystectomy.","authors":"Junfeng Zhang, Bin Li, Jiangbo Qu, Yanan Li, Jiahui Liu, Huibin Mao","doi":"10.4293/JSLS.2025.00032","DOIUrl":"10.4293/JSLS.2025.00032","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the effects of the pressure-controlled volume-guaranteed ventilation (PCV-VG) mode on pulmonary function in patients with pneumoconiosis undergoing laparoscopic cholecystectomy.</p><p><strong>Methods: </strong>Forty patients with pneumoconiosis scheduled for elective laparoscopic cholecystectomy under general anesthesia were randomly divided into two groups using a random number table method: the PCV-VG mode group and the volume-controlled ventilation (VCV) mode group. The primary outcome was lung ultrasound score (LUS) after entering the operating room (T0), at the end of surgery (T3), 30 minutes after tracheal extubation (T4), and 2 hours postoperatively (T5). Peak airway pressure (Ppeak) and plateau pressure (Pplat) were recorded 2 minutes before (T1) and 20 minutes after the initiation of artificial pneumoperitoneum (T2). Arterial blood gas analyses were performed at T0, T2, and T4 to calculate the oxygenation index (OI).</p><p><strong>Results: </strong>Compared to the VCV group (n = 20), the PCV-VG group (n = 20) exhibited significantly improvement of median LUS at T3, T4, and T5 (all <i>P</i> < .05). Significantly lower Ppeak and Pplat were found in PCV-VG group at T1 (16.2 ± 1.81 and 14.6 ± 1.85) and T2 (24.3 ± 2.75 and 19.7 ± 3.08) (<i>P</i> < .05). Additionally, median OI significantly improved at T2 and T4 in PCV-VG group (<i>P</i> < .05). No early postoperative pulmonary complications were found in both groups.</p><p><strong>Conclusion: </strong>For patients with pneumoconiosis undergoing laparoscopic cholecystectomy, the PCV-VG mode can reduce intraoperative airway pressures and early postoperative LUS values, decrease ventilation loss, and improve perioperative oxygenation.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Medicine: A Specialty-Level Overview of Emerging AI Trends.","authors":"Jesse L Popover, Spencer P Wallace, Jeremie Feldman, George Chastain, Chris Kalathia, Adnan Imam, Majd Almasri, Paul G Toomey","doi":"10.4293/JSLS.2025.00041","DOIUrl":"10.4293/JSLS.2025.00041","url":null,"abstract":"<p><strong>Objective: </strong>Artificial intelligence (AI) is a turning point in medical advancement. Despite the burgeoning research in this field, there exists a general lack of overview of where AI is being most utilized. This study reviews and describes techniques and trends of AI in the major medical specialties.</p><p><strong>Method: </strong>A literature search was conducted through PubMed in 2024 using two different search methods. Twenty-nine medical specialties were included, including all 24 major medical board specialties and five additional subspecialties.</p><p><strong>Results: </strong>There were 143,578 publications involving AI identified with most these (87%) published in the last ten years (124,206) and 52% (74,239) in the last two years. Radiology and Pathology publications were the largest cohorts, 18% (25,319) and 17% (23,828), respectively. Plastic Surgery (1,053), Hepatobiliary (662), and Allergy/Immunology (449) were the least published. There has been a 10,859% growth rate in annual publications across all medical specialties, with Ophthalmology and Preventative Medicine being the fastest-growing areas of research despite Radiology and Pathology being the most researched to date.</p><p><strong>Conclusion: </strong>This review underscores AI's profound impact on medical research, highlighting its significant growth and utilization across various specialties. AI's influence is most pronounced in Radiology and Pathology, but the substantial increase in publications in Ophthalmology and Preventative Medicine suggests new emerging areas of focus. The ongoing expansion of AI in medicine presents a promising horizon for addressing complex healthcare challenges, fostering a deeper and more comprehensive integration across all specialties.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experiences with Standard Behavioral Restrictions after Total Laparoscopic Hysterectomy.","authors":"R Gina Silverstein, Katie LeCroy, Noor Dasouki Abu-Alnadi, Erin Carey, Asha McClurg","doi":"10.4293/JSLS.2025.00035","DOIUrl":"10.4293/JSLS.2025.00035","url":null,"abstract":"<p><strong>Background and objectives: </strong>After hysterectomy, patients are counseled on behavioral limitation, such as avoiding vaginal intercourse and heavy lifting, to try to optimize healing. There are limited data on the benefits of these restrictions and on the impact on patients. This study aimed to evaluate patients' adherence to and perception of behavioral restrictions after total laparoscopic hysterectomy.</p><p><strong>Methods: </strong>A cross-sectional survey study of patients who underwent total laparoscopic hysterectomy and completed the survey at their postoperative appointment between January 3 and March 31, 2023. Patients had been counseled to avoid submersion in water, strenuous exercise, and lifting > 10 pounds for at least 6 weeks, and to avoid vaginal penetration for 12 weeks after surgery. Convenience sampling was used.</p><p><strong>Results: </strong>A total of 71 patients were eligible and 50 (70%) participated. The mean time to postoperative appointment was 32 days. Participants reported inconsistent adherence to behavioral guidelines. 49/50 (98%) patients avoided vaginal penetration, 46/50 (92%) avoided submerging in water, 21/49 (43%) avoided lifting > 10 pounds. Within 4 weeks, > 90% of patients returned to driving, housework, and shopping and 21/36 (58%) of employed patients returned to work. 21/47(45%) of participants reported that adhering to postoperative restrictions was at least \"a little bit challenging,\" with home responsibilities cited as the primary challenge.</p><p><strong>Conclusion: </strong>Patients inconsistently followed behavioral restrictions after total laparoscopic hysterectomy and described them as difficult to follow due to other responsibilities. Future studies should explore the necessity of postoperative restrictions and strategies for improving adherence to restrictions that optimize patient safety.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Port and Conventional Laparoscopic Appendectomy in Children with Acute Appendicitis.","authors":"Menglei Wang, Jianyu Wang, Bingshan Xia, Hai Zhou, Chunbao Guo","doi":"10.4293/JSLS.2025.00061","DOIUrl":"10.4293/JSLS.2025.00061","url":null,"abstract":"<p><strong>Objective: </strong>The aim is to evaluate and contrast the effectiveness of single-port versus conventional laparoscopic appendectomy in pediatric cases, providing a rigorous assessment of their respective therapeutic impacts.</p><p><strong>Methods: </strong>A retrospective study was performed on pediatric appendicitis cases operated on by a single primary surgeon using either single-port or conventional laparoscopic techniques between July 2015 and June 2024. The study encompassed variables such as age, onset timing, operative duration, hospital stay, and pathological classification, to compare the therapeutic outcomes of both surgical approaches.</p><p><strong>Results: </strong>The retrospective review included 1,435 pediatric cases of acute appendicitis, with 1,239 in the conventional laparoscopic group and 196 in the single-port laparoscopic group. The conventional laparoscopic procedure utilized a 3-port technique, whereas the single-port laparoscopic group employed a silicone 3-port Trocar. Statistical analysis of age, onset timing, operative duration, and hospital stay revealed no significant differences between the 2 groups. Pathological examination of appendicitis types, as determined by the χ² test, indicated no significant disparities in distribution across the groups.</p><p><strong>Conclusion: </strong>Given that pediatric surgeons possess adept laparoscopic surgical skills, single-port laparoscopic surgery is a viable alternative to conventional laparoscopic surgery for the treatment of acute appendicitis in children, offering comparable therapeutic benefits.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hand-Assisted Laparoscopic Colectomy for Complicated Colorectal Disease in Emergency Settings.","authors":"Donghyoun Lee, Yoon Hyung Kang, Yongbog Kim, Sung Ryol Lee, Hyung Ook Kim, Hungdai Kim, Ho-Kyung Chun, Kyung Uk Jung","doi":"10.4293/JSLS.2025.00039","DOIUrl":"10.4293/JSLS.2025.00039","url":null,"abstract":"<p><strong>Background and objectives: </strong>The safety and effectiveness of laparoscopic approaches for emergency colorectal surgery are not yet fully established, though their use is increasing with studies reporting laparoscopic colectomy is safe and feasible for appropriately selected patients. Hand-assisted laparoscopy (HAL) involves inserting one hand into the abdomen through a small incision, offering advantages that may facilitate laparoscopic procedures in emergencies. This study reports our experience with emergency HAL colectomy.</p><p><strong>Methods: </strong>This was a retrospective review of consecutive colorectal emergency cases treated with HAL colectomy in a tertiary referral center. Patient demographics, indications for surgery, operative details, and postoperative outcomes were analyzed. Survival rates were calculated for cases with malignancy.</p><p><strong>Results: </strong>From February 2015 to July 2019, HAL was applied to all emergency colectomy cases in patients with an American Society of Anesthesiologists (ASA) score of I-III. A total of 50 patients treated with HAL colectomy for complicated colorectal disease were reviewed. Twenty-five patients (50%) had an obstruction which required an intraoperative decompression procedure or intraoperative antegrade colonic irrigation. Thirty-eight patients (76%) had perforation. There were 2 cases of open conversion (4%). The median duration of the operation was 160 minutes. The median amount of estimated blood loss was 250 mL. The median time of postoperative stay was 12 days. The postoperative complication rate associated with the operation was 26% (13/50). There were 2 postoperative mortalities.</p><p><strong>Conclusion: </strong>HAL appears to be a feasible option in emergency colectomy for ASA I-III patients and may be beneficial in specific surgical practice contexts.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic Management of Grade C Anastomotic Leak following Left-Sided Colorectal Resection.","authors":"Chinasa P Okonkwo, Martin Infante Altamirano, Amunu Adogowa, Henry J Lujan","doi":"10.4293/JSLS.2025.00053","DOIUrl":"10.4293/JSLS.2025.00053","url":null,"abstract":"<p><strong>Background: </strong>Management of left-sided colorectal Grade C anastomotic leak (AL) has traditionally been managed via laparotomy. However, with the growing adoption of minimally invasive techniques, recent literature suggests that laparoscopic surgery provides a safe and viable alternative for managing Grade C leaks.</p><p><strong>Methods: </strong>This study is a case series that consists of 7 adults that underwent laparoscopic reintervention of purulent or feculent peritonitis from left-sided colorectal AL during the period of 2016-2024 at our institution. Outcomes measured included days to presentation, operative times, hospital stay, morbidity, mortality, and rates of stoma closure.</p><p><strong>Results: </strong>Of the 7 patients, 6 of them had purulent peritonitis and one had feculent peritonitis. The average time from index operation to clinically evident AL was 6 days. The patients were managed with laparoscopic with drainage, colorrhapy and Hartmann's procedure.Complications include subhepatic fluid collection, hematoma, infected seroma. The average operative time was 145.3 min. The average length of hospital stay (LOS) after reoperation was 11 days. All patients had their stoma reversed within an average of 90 days. No deaths occurred.</p><p><strong>Conclusion: </strong>MIS approach to Grade C AL in left-sided colorectal resection is safe and feasible. It can be performed with low morbidity and mortality and high rates of stoma closure.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Positional Peripheral Nerve Injury in Robotic Laparoscopic Radical Prostatectomy.","authors":"Şenay Göksu, Gülşah Karaören, Ahmet Tahra, Abdurrahman İnkaya, Eyüp Veli Küçük, Nurten Bakan","doi":"10.4293/JSLS.2025.00031","DOIUrl":"10.4293/JSLS.2025.00031","url":null,"abstract":"<p><strong>Background and objectives: </strong>One of the responsibilities of the anesthesiologist is to maintain the physiologic anatomic position during surgery. Postoperative positional peripheral nerve injury (PPPNI) inevitably may occur during robot-assisted laparoscopic radical prostatectomy (RARP) in steep-Trendelenburg-lithotomy positioning. The primary aim of the study was to identify incidence and risk factors for the development of PPPNI in the RARP and the secondary aim was to identify the most common types and duration of PPPNI.</p><p><strong>Methods: </strong>After ethics committee and patients approval, patients who underwent RARP in past 7 years were retrospectively evaluated. Patients with known peripheral neuropathy were excluded. Patient demographics, American Society of Anesthesiologists (ASA) score, body mass index (BMI), Charlson comorbidity index (CCI), operative time (OT), and Trendelenburg time (TT) were obtained from the records. Patients were asked if they had PPPNI and other descriptive questions.</p><p><strong>Results: </strong>A total of 868 patients were included in the study. The mean age, BMI, ASA risk score, and CCI were 63.44 ± 6.68 years, 27.46 ± 2.75 kg/m², 1.76 ± 0.62, and 2.41 ± 0.89, respectively. PPPNI rate was 5.6% (49 patients). The mean OT, TT and recovery time were 168.83 ± 52.1 minutes, 110.74 ± 46.33 minutes, and 6.5 ± 2.81 months, respectively. The BMI, OT, and TT values of patients with PPPNI were significantly higher than those of patients without PPPNI (<i>P</i> < .01). The cutoff values were 29, 212, and 157 minutes, respectively. Of the 49 patients with PPPNI, 55.1% had upper extremity injuries (pain 51.9%), 51% had lower extremity injuries (motor deficit 58.3%), and 6.1% had injuries to both. Six patients claimed PPPNI.</p><p><strong>Conclusion: </strong>The RARP is associated with an elevated risk of PPPNIs, particularly in cases of prolonged OT, TT, and high BMI.</p>","PeriodicalId":17679,"journal":{"name":"JSLS : Journal of the Society of Laparoendoscopic Surgeons","volume":"29 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}