JRSM Open最新文献

{"title":"Acute subcutaneous emphysema: A rare clinical presentation of large bowel perforation.","authors":"Matthew Dunckley, Frank Smedley, Brian Andrews","doi":"10.1177/20542704231153529","DOIUrl":"10.1177/20542704231153529","url":null,"abstract":"<p><p>These atypical presentations of colonic perforation illustrate the importance of considering acute intra-abdominal pathology when subcutaneous emphysema is identified.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 2","pages":"20542704231153529"},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/ad/10.1177_20542704231153529.PMC9912557.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10707041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long recurrence-free survival of localized rectal melanoma after abdominoperineal resection in comparison to partial excision and highlighting the place of immunotherapy: A case report.","authors":"Othmane Bourouail, Noureddine Njoumi, Youssef Elmahdaouy, Mohamed Fahssi, Mbarek Yaka, Abderrahmane Hejjouji, Abdelmounaim Ait Ali","doi":"10.1177/20542704221148059","DOIUrl":"10.1177/20542704221148059","url":null,"abstract":"<p><p>Rectal malignant melanomas (RMM) are remarkably uncommon, the rectal location represents less than one percent of all rectal cancer. Because of its low global survival rate, the surgical strategy is a subject of controversy for attaining a r0 resection. the palliative treatment is also debateable, but recently; radiotherapy and immunotherapy became the preferred treatment and offer the best outcome. to ensure r0 resection, abdominoperineal resection (apr) is considered the main surgical option, but because of its morbidity and functional limitations, local excision techniques such as endoscopic mucosal resection (emr) combined with chemoradiotherapy are being increasingly performed to preserve the quality of life and reduce local recurrence rate. In this report, we evaluate the place that apr still keeps as surgical procedure in comparison to partial excision. we report a case of a 72 years old patient, who presented rectal syndrome with rectorrhagia for 2 months, the diagnosis of localized rectal melanoma was confirmed by endoscopy, magnetic resonance imaging, histological analysis tissue with immunohistochemistry. the procedure strategy was a surgical treatment with apr. After a long recurrence-free survival period, the patient develops local recurrence and immunotherapy-resistant metastasis.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 2","pages":"20542704221148059"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/3f/10.1177_20542704221148059.PMC9905026.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9410360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antipsychotic drugs may contribute to venous thromboembolism - a case report and review literature.","authors":"Adnan Hajjiah,&nbsp;Ossama Maadarani,&nbsp;Zouheir Bitar,&nbsp;Khaled Alfasam,&nbsp;Boutros Hanna,&nbsp;Mohamad Elhabibi","doi":"10.1177/20542704221132142","DOIUrl":"https://doi.org/10.1177/20542704221132142","url":null,"abstract":"<p><p>Use of antipsychotic drugs has been associated with increased risk of venous thromboembolism in several observational studies with unclear mechanism. We present a case of a patient who experienced a significant event of venous thromboembolism after a few months exposure to atypical antipsychotic drug for his bipolar mood disorders.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 1","pages":"20542704221132142"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/66/10.1177_20542704221132142.PMC9829988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9119100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical stenosis of left main coronary artery as a late presentation after transcatheter aortic valve replacement: A case report and review literature.","authors":"Jadan Alsaddah,&nbsp;Abdullah Alenezi,&nbsp;Ossama Maadarani,&nbsp;Zouheir Bitar,&nbsp;Rahaf Alfadhli","doi":"10.1177/20542704221132135","DOIUrl":"https://doi.org/10.1177/20542704221132135","url":null,"abstract":"<p><p>Transcatheter aortic valve replacement (TAVR) is an alternative treatment for selected patients with severe aortic valve stenosis who are at high risk for conventional surgery. Critical stenosis of left main coronary artery as a late complication after TAVR is quite rare.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 12","pages":"20542704221132135"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8d/6b/10.1177_20542704221132135.PMC9729988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10332629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of the Indian clinical practice guidelines for the management of cardiovascular conditions.","authors":"Rupasvi Dhurjati,&nbsp;Vidya Sagar,&nbsp;Raju Kanukula,&nbsp;Nusrath Rehana,&nbsp;Padinhare P Mohanan,&nbsp;Mark D Huffman,&nbsp;Soumyadeep Bhaumik,&nbsp;Abdul Salam","doi":"10.1177/20542704221127178","DOIUrl":"https://doi.org/10.1177/20542704221127178","url":null,"abstract":"<p><p>To assess the quality of Indian clinical practice guidelines (CPG)s for the management of cardiovascular conditions, MEDLINE, Embase, Google Scholar and websites of relevant medical associations and government organisations were searched, from inception until August 2020, to identify Indian CPGs for the management of cardiovascular disease (CVD) conditions, produced in or between 2010 and 2019. Excluded were CPGs that were not specific to India, focused on alternative systems of medicine, of non-CVD conditions (even if they included a component of CVD), and those related to the electronic devices, cardiac biomarkers, or diagnostic procedures. Quality of the each included CPG was assessed using the AGREE II tool by four reviewers in duplicate, independently. Each AGREE II domain score and overall quality score was considered low (≤40%), moderate (40.1%-59.9%), and high (≥60%). Of the 23 CPGs included, six (26%) were reported to be adapted from other CPGs. Fourteen (61%) CPGs were produced by medical associations, six (26%) by individual authors and three (13%) by government agencies. Based on the AGREE II overall quality score, two (9%) CPGs were of high quality, four (17%) and seventeen (74%) CPGs were of moderate and low quality, respectively. Except for scope and purpose, and clarity of presentation all other domains were rated low. The quality of most Indian CPGs for managing CVD conditions assessed using the AGREE II tool was moderate-to-low. Combined efforts from different stakeholders are needed to develop, disseminate and implement high-quality CPGs while identifying and addressing barriers to their uptake to optimize patient care and improve outcomes.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 12","pages":"20542704221127178"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/36/10.1177_20542704221127178.PMC9730011.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10337288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open science and conflict of interest policies of medical and health sciences journals before and during the COVID-19 pandemic: A repeat cross-sectional study: Open science policies of medical journals.","authors":"Antoni D Gardener, Ellen J Hick, Chloe Jacklin, Gifford Tan, Aidan G Cashin, Hopin Lee, David Nunan, Elaine C Toomey, Georgia C Richards","doi":"10.1177/20542704221132139","DOIUrl":"10.1177/20542704221132139","url":null,"abstract":"<p><strong>Objectives: </strong>To audit the transparent and open science standards of health and medical sciences journal policies and explore the impact of the COVID-19 pandemic.</p><p><strong>Design: </strong>Repeat cross-sectional study.</p><p><strong>Setting: </strong>19 journals listed in Google Scholar's Top Publications for health and medical sciences.</p><p><strong>Participants: </strong>Blood, Cell, Circulation, European Heart Journal, Gastroenterology, Journal of Clinical Oncology, Journal of the American College of Cardiology, Nature Genetics, Nature Medicine, Nature Neuroscience, Neuron, PLoS ONE, Proceedings of the National Academy of Sciences, Science Translational Medicine, The British Medical Journal, The Journal of the American Medical Association, The Lancet, The Lancet Oncology, and The New England Journal of Medicine.</p><p><strong>Main outcome measures: </strong>We used the Transparency and Openness Promotion (TOP) guideline and the International Committee of Medical Journal Editors (ICMJE) requirements for disclosing conflicts of interest (COIs) to evaluate journals standards.</p><p><strong>Results: </strong>TOP scores slightly improved during the COVID-19 pandemic, from a median of 5 (IQR: 2-12.5) out of a possible 24 points in February 2020 to 7 (IQR: 4-12) in May 2021, but overall, scores were very low at both time points. Journal policies scored highest for their adherence to data transparency and scored lowest for preregistration of study protocols and analysis plans and the submission of replication studies. Most journals fulfilled all ICMJE provisions for reporting COIs before (84%; n  =  16) and during (95%; n  =  18) the COVID-19 pandemic.</p><p><strong>Conclusions: </strong>The COVID-19 pandemic has highlighted the importance of practising open science. However, requirements for open science practices in audited policies were overall low, which may impede progress in health and medical research. As key stakeholders in disseminating research, journals should promote a research culture of greater transparency and more robust open science practices.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":" ","pages":"20542704221132139"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ec/1c/10.1177_20542704221132139.PMC9666860.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40487734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute ECG changes in a woman presenting to coronary care with fluctuating consciousness.","authors":"Hannah Parker,&nbsp;Ahmed El-Medany,&nbsp;Robert Crossley","doi":"10.1177/20542704221123438","DOIUrl":"https://doi.org/10.1177/20542704221123438","url":null,"abstract":"<p><p>We present the case of a 67-year-old woman brought into the coronary care unit (CCU) with a suspected ST-segment elevation myocardial infarction (STEMI) due to lateral ST-segment elevation on her 12-lead electrocardiogram (ECG) and a significant troponin rise, but no reported chest pain and a fluctuating consciousness level. Whilst in CCU, she deteriorated further with a reduction in consciousness and sluggish pupillary reflexes, warranting urgent computed tomography (CT) of her brain, which confirmed extensive subarachnoid haemorrhage (SAH) with early evidence of hydrocephalus. She was therefore transferred to the local tertiary neurosurgical centre for endovascular coiling. ECG changes alongside a raised troponin are not uncommon findings in SAH and clinicians should exercise vigilance and consider urgent brain imaging in the absence of chest pain and presence of neurological deficit, to prevent adverse events from unnecessary antiplatelet or anticoagulant therapy, and invasive coronary angiography. SAH is a medical emergency and prompt recognition and referral for neurosurgical intervention is integral for optimal patient outcome.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 11","pages":"20542704221123438"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/bf/10.1177_20542704221123438.PMC9663640.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare infective cause for recurrent exacerbations and poor asthma control - <i>Mycobacterium kumamotonense</i>.","authors":"Ben G Marshall, Parsa Keyvani, Adrian R Martineau","doi":"10.1177/20542704221124013","DOIUrl":"10.1177/20542704221124013","url":null,"abstract":"","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 10","pages":"20542704221124013"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/35/84/10.1177_20542704221124013.PMC9561674.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33514840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative study of factors influencing COVID-19 vaccine hesitancy among South Asians in London.","authors":"Raj S Chandok,&nbsp;Poonam Madar,&nbsp;Azeem Majeed","doi":"10.1177/20542704221123430","DOIUrl":"https://doi.org/10.1177/20542704221123430","url":null,"abstract":"<p><strong>Objectives: </strong>This qualitative study sought to elicit the views and experiences of patients and health-care professionals to identify the factors associated with COVID-19 vaccine hesitancy among South Asians in London.</p><p><strong>Design: </strong>In-depth semi-structured telephone and virtual interviews.</p><p><strong>Setting: </strong>UK.</p><p><strong>Participants: </strong>Convenience and purposive sample of 12 individuals including patients, clinicians, and a medical receptionist.</p><p><strong>Main outcome measures: </strong>Our dataset identifies and explains the reasons for distinguishing between those individuals who are <i>COVID-19 vaccine-hesitant,</i> and those who are <i>COVID-19 vaccine-anxious.</i></p><p><strong>Results: </strong>COVID-19 vaccine hesitancy and the decision on whether to - or not to - vaccinate against COVID-19 involves ongoing and unresolved inner conflict about COVID-19 vaccines. Our findings therefore suggest that some individuals may be existing in a state of <i>inbetweeness;</i> where they are neither pro nor anti vaccination, while simultaneously questioning the many 'truths' surrounding COVID-19 and not just one truth such as the safety of COVID-19 vaccines. We argue that this <i>in-between</i> state is intensified by technology and social media; culminating in the <i>Rashomon Effect,</i> whereby a combination of truths, fractured truths, subjective realities, and unreliable or contradictory sources impact on our perceptions of COVID-19.</p><p><strong>Conclusions: </strong>Given the complexities arising from the multiple factors influencing vaccine hesitancy and scepticism, 'quick fixes' and 'one size fits all' solutions to address COVID-19 vaccine hesitancy will be ineffective. Therefore, promoting trust and prioritising good after-care as well as on-going care as a response to the effects of the pandemic is vital.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 10","pages":"20542704221123430"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/dc/10.1177_20542704221123430.PMC9536136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33498340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial Mediterranean fever: a differential diagnosis for the surgical abdomen.","authors":"Nikita Cliff-Patel,&nbsp;Baasil Syed Yusuf,&nbsp;Shazia Hamdani,&nbsp;Veqas Ziauddin","doi":"10.1177/20542704221123433","DOIUrl":"https://doi.org/10.1177/20542704221123433","url":null,"abstract":"<p><p>FMF is characterised by dysregulation of the inflammatory process in the body, presenting as recurrent episodes of serositis. Patients with FMF commonly present with episodes of fever, peritonitis, synovitis, pleuritis, arthritis, and occasionally pericarditis. We present a case of a young 19-year old female, who presented to hospital four times over several months with intermittent fevers, abdominal pain and pleuritic chest pain. After being initially admitted under the surgical team, she was reviewed by the medical team who referred her for genetic testing, which subsequently confirmed the diagnosis. She was started on colchicine, and her symptoms remain well controlled one-year post diagnosis.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"13 9","pages":"20542704221123433"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/71/10.1177_20542704221123433.PMC9445484.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33455369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}