{"title":"How to Ensure Equitable Access to Covid-19 Vaccine","authors":"R. Popovian","doi":"10.35248/2157-7560.20.11.430","DOIUrl":"https://doi.org/10.35248/2157-7560.20.11.430","url":null,"abstract":"","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"22 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76288375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunomodulation and its Therapeutic Applications","authors":"R. Ferner","doi":"10.35248/2157-7560.20.S8.E003","DOIUrl":"https://doi.org/10.35248/2157-7560.20.S8.E003","url":null,"abstract":"For the treatment of established infections, attempts to shift the immune reaction toward a Th1-type phenotype are desirable. For the treatment of cancer, efforts have focused mainly in making the cancer the well-liked target of the system of the patient. To the present effect, a spread of approaches are used, including cytokines, anti-CTL-4, tumor-specific antibodies and cellular therapies using tumor infiltrating lymphocytes and even somatic cell transplantation.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"20 1","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77108985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and Attitudes regarding influenza vaccination among pregnant women in Tunisia","authors":"G. Kharroubi","doi":"10.35248/2157-7560.20.11.E422","DOIUrl":"https://doi.org/10.35248/2157-7560.20.11.E422","url":null,"abstract":"Vaccination coverage among expectants remains suboptimal worldwide. To achieve a successful vaccination program, it is essential to understand reasons behind the acceptance of vaccination or its rejection. The present study aimed to describe knowledge and attitudes related to flu vaccine during pregnancy among Tunisian women. A national survey type Knowledge, and Attitudes was conducted during the 2018-19 flu season using a self-weighted two stages sampling method. Data were collected through face-to-face interviews with pregnant women present at the obstetrics outpatient consultations of the selected primary or secondary health care facilities. A total of 1157 pregnant women agreed to be interviewed. More than half of participants (60.3%) had heard about the influenza vaccine before. Among them, only 75 (10.9%) declared that they had enough information about safety and side effects of influenza vaccine. When asked about flu vaccine safety, most than half disagreed with those statements in disfavor of vaccine during pregnancy: the vaccine can be dangerous for pregnant women (62.2%), for the fetus (64.7%), for the newborn (66.7%) and can cause the flu (82.5%). Whereas, less than half were in agreement with those statements in favor of influenza vaccine effectiveness: flu vaccination of pregnant women helps to protect the mother (47.8%), the fetus (36.0%) and the unborn child (34.2%) against influenza.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"20 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82359923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Personalizing Vaccination for Infectious Disease in the 21st Century","authors":"R. Gorczynski","doi":"10.35248/2157-7560.20.S5:005","DOIUrl":"https://doi.org/10.35248/2157-7560.20.S5:005","url":null,"abstract":"Current approaches to vaccination have several underlying assumptions, namely that following immunization most individuals are at similar risk of the disease considered; will react immunologically in the same way (with protective antibodies and/or cell-mediated reactivity) with equivalent and minimal side effects; and that vaccination dosing and frequency of administration does not vary in the population at large. As a result, a widespread delivery of vaccines has been achieved for a number of infectious diseases, with effective control for many of those. It is clear that a weakness of this approach, made manifest with our increasing knowledge of the genomic and proteomic approach to medicine which has come to the fore in the last decade or so, is that it discounts the growing evidence for individual variability in risk; in immune responsiveness; and in response to different doses of vaccine. While this evidence grew from a focus on tailoring individual approaches to cancer therapy, and has revolutionized our thoughts on drug therapy, drug pharmacogenomics and toxicity and the importance of understanding at the individual, not population level, unique responses to treatment, application of the same approach to vaccines for infectious disease has not had a similar attention. Indeed, not only does consideration of individual specific factors challenge a traditional public-health level paradigm of infectious disease vaccinology, and confront newer approaches based on genetically encoded individuality in response to pathogen challenge, but the cost-benefit of such an approach has, to the author’s knowledge, not been considered at all. The review below will consider these issues in greater detail, with a final focus on how this might dictate our global responses to emerging infections.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"95 1","pages":"23-30"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82891260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Debasis Datta, S. Ghosal, B. Sinha, S. Datta, Twisha Chakraborty, K. Gangopadhyay, A. Dutta
{"title":"No Role of HCQ in COVID-19 Prophylaxis: A Survey amongst Indian Doctors","authors":"Debasis Datta, S. Ghosal, B. Sinha, S. Datta, Twisha Chakraborty, K. Gangopadhyay, A. Dutta","doi":"10.35248/2157-7560.20.S6.002","DOIUrl":"https://doi.org/10.35248/2157-7560.20.S6.002","url":null,"abstract":"The COVID-19 pandemic is being tackled on two fronts-prevention and treatment. In addition to behavioural strategies and vaccines (eagerly awaited), pharmacotherapy is also being employed in certain regions as a preventive strategy. In India, hydroxychloroquine (HCQ), ivermectin, a variety of vitamin supplements are being used, with HCQ being the most popular among healthcare professionals. In addition to the evidence-based recommendations, it is important to ascertain the situation on the ground. We conducted a multicentric survey among physicians from a wide range of specialities to ascertain the usage on HCQ and its effects of COVID-19 prevention. We did not find any significant impact of HCQ on the prevention of COVID-19 (p=0.54) independent of the duration of its usage. This pilot project has the potential to act as a backbone for a larger study exploring the impact of pharmacological intervention on COVID-19 prevention.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"2012 1","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83159279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhance and Expand Access to Vaccines","authors":"R. Popovian, David Hering","doi":"10.35248/2157-7560.20.S5:006","DOIUrl":"https://doi.org/10.35248/2157-7560.20.S5:006","url":null,"abstract":"If recent events have taught us one thing, it is that vaccines are a critical tool to help combat today’s public health challenges and prevent those yet to come. The recent drop in pediatric vaccination rates has led to a resurgence of vaccine-preventable diseases such as measles. Meanwhile, the coronavirus outbreak shows us that when pandemics occur, our healthcare system needs to have a way to quickly react and get preventative treatments to a broad population in a timely manner.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"42 1","pages":"31-32"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90900470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-organization and Effective Cutaneous Vaccination","authors":"Q. Wangi","doi":"10.35248/2157-7560.20.11.E414","DOIUrl":"https://doi.org/10.35248/2157-7560.20.11.E414","url":null,"abstract":"11 years ago the first journal devoted entirely to the publication of research in Journal of Vaccines & Vaccination. There are some journals about the findings of international comparisons show that countries with health system based on strong primary care have better health at lower costs. The journal covers a broad spectrum of topics for study that discusses theoretical and empirical aspects of Vaccines like leadership, management, and administration of public health systems, Human Vaccine Trials, Veterinary Vaccines, Cancer Vaccines, Vaccine Adjutants and hospital networks. The journal solicits manuscripts that discuss technical and medical advancements in Decision Science, Children Vaccines, HIV Vaccine Care Management, Vaccines, Quality and Access. Where we encourage authors to provide insight into their recently published journal.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"31 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90401187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 in India: Health Implications and Treatment Needs of People Who Use Drugs (PWUD) and Patients with Substance Use Disorders (SUD)","authors":"G. Ghosh","doi":"10.35248/2157-7560.20.11.427","DOIUrl":"https://doi.org/10.35248/2157-7560.20.11.427","url":null,"abstract":"Introduction: The Covid-19 actuated lockdown in India had put huge number of People who use drugs (PWUD) in panicky over their hankering for substance use with flexibly chain interruptions. Point of this paper was to comprehend the Covid-19 incited issues looked by PWUD and those with Substance Use Disorders (SUD) in India. Techniques: A fast subjective exploration was directed distantly from May to early June 2020, during lockdown period in India, with assent situated inside and out meetings with key partners from national organizations and medication deaddiction focus in East and Northern-East India. Results: The current general wellbeing emergency raises genuine extra worries for the prosperity of PWUD as they run similar dangers of disease by COVID-19 because of fundamental ceaseless ailments. During the current Covid-19 pandemic, there has been steady missing of treatment administrations for Patients with Substance Use Disorders (SUD). The individuals who required treatment during lockdowns confronted issues as government upheld sedate deaddiction habitats, which halted new affirmation however of late began new confirmation yet in diminished numbers. The outpatient administrations of medication treatment focuses (DTC) at some administration emergency clinics couldn't work. The Opioid Substitution Therapy focuses, however began apportioning of methadone on fortnightly and buprenorphine on seven-day top off premise, yet there remained travel related issues and detailed badgering during lockdown stage. Conclusion: Specific measures to mitigating health service needs of PWUD in India should be put inplace, taking lessons from the current pandemic situation.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"22 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78090726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiology and Public Health 2020: Reasons Leading to Influenza Vaccine Acceptance and Decline among Tunisian Healthcare Workers","authors":"G. Kharroubi","doi":"10.35248/2157-7560.20.11.E421","DOIUrl":"https://doi.org/10.35248/2157-7560.20.11.E421","url":null,"abstract":"Despite of recommendations, influenza vaccine (IV) coverage among healthcare workers remains low in many countries. We aimed in this study to assess the main reasons leading to flu vaccine acceptance and decline among Tunisian healthcare workers through a study of knowledge, attitudes and practices towards influenza immunization. It was a cross sectional study conducted in Tunisian primary and secondary healthcare facilities from March to May 2019. Health professionals were enrolled according to a self-weighted multistage sampling. A face to face questionnaire was administered to participants. Reasons leading to IV acceptance and decline were assessed through open-ended questions. A total of 1230 HCWs were included in the study with a mean age of 44.5±9.3 years and a sex-ratio (M: F) of 0.25. Among participants, 43.1% (95%CI: [40.3-46.0]) were willing to receive the flu vaccine if recommended to caregivers and provided for free. According to participating healthcare workers, the main three reasons leading to vaccine acceptance were: self-protection (73.8 % [71.3-76.3]) and family and patients’ protection (49.2% [46.4-52.0] and 28.2% [25.8-30.7] respectively). Regarding reasons leading to IV decline, fear of the vaccine side effects (48.0% [40.3-46.0]), feeling not concerned by the flu vaccine (31.8% [29.3-34.4]) and doubt about vaccine efficacy (31.6% [28.8-34.3]) were the most frequent cited reasons. Less than half of participants were willing to receive the IV. Fear of flu vaccine side effects was the most frequently reported reason leading to vaccine decline. Health authorities should thus organize regular training sessions in healthcare facilities aiming to educate caregivers about IV composition and safety.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"18 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85228002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19: Waiting for the Vaccine. What Needs to be Done","authors":"M. Scialpi, A. Blasi, Longo Ferdin","doi":"10.35248/2157-7560.20.S6.003","DOIUrl":"https://doi.org/10.35248/2157-7560.20.S6.003","url":null,"abstract":"An increase of confirmed asymptomatic COVID-19 patients emerges from the second phase of the COVID-19 pandemic. Waiting for the vaccine, the employment of large-scale testing to identify and isolate asymptomatic individuals is the only solution to contain and control the spread of the disease.","PeriodicalId":17656,"journal":{"name":"Journal of Vaccines and Vaccination","volume":"21 1","pages":"7-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81780801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}