Journal of women's health最新文献

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Evaluating the Effect of Depression, Anxiety, and Post-Traumatic Stress Disorder on Anti-Müllerian Hormone Levels Among Women Firefighters. 评估抑郁、焦虑和创伤后应激障碍对女消防员抗<s:1>勒氏激素水平的影响。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2024-12-20 DOI: 10.1089/jwh.2024.0534
Michelle A Valenti, Leslie V Farland, Kaiwen Huang, Yiwen Liu, Shawn C Beitel, Sara A Jahnke, Brittany Hollerbach, Caitlin C St Clair, John J Gulotta, Jamie J Kolar, Derek J Urwin, Paola Louzado-Feliciano, Jordan B Baker, Kepra L Jack, Alberto J Caban-Martinez, Jaclyn M Goodrich, Jefferey L Burgess
{"title":"Evaluating the Effect of Depression, Anxiety, and Post-Traumatic Stress Disorder on Anti-Müllerian Hormone Levels Among Women Firefighters.","authors":"Michelle A Valenti, Leslie V Farland, Kaiwen Huang, Yiwen Liu, Shawn C Beitel, Sara A Jahnke, Brittany Hollerbach, Caitlin C St Clair, John J Gulotta, Jamie J Kolar, Derek J Urwin, Paola Louzado-Feliciano, Jordan B Baker, Kepra L Jack, Alberto J Caban-Martinez, Jaclyn M Goodrich, Jefferey L Burgess","doi":"10.1089/jwh.2024.0534","DOIUrl":"10.1089/jwh.2024.0534","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To assess whether depression, anxiety, and post-traumatic stress disorder (PTSD) are associated with serum anti-Müllerian hormone (AMH) levels. <b><i>Study Design:</i></b> We used data from a sample of women firefighters from the Fire Fighter Cancer Cohort Study. Participant demographics, reproductive history, and self-reported clinical diagnosis of anxiety, depression, and PTSD were collected with serum for AMH analysis at enrollment. <b><i>Main Outcome Measure:</i></b> Linear regression models were used to estimate the association between anxiety, depression, and PTSD and log transformed AMH levels adjusted for age years (continuous and squared) and body mass index. Percent difference in AMH was calculated by [exp(β) - 1] × 100. <b><i>Results:</i></b> Among 372 participants, with mean ± standard deviation age 32.54 ± 6.32, clinical diagnoses were reported as follows: depression (15%), anxiety (18.2%), or PTSD (8.7%). No statistically significant association was observed between depression and AMH levels (-22%Δ, 95% confidence interval [CI]: -47.3, 14.5). Women firefighters with a history of anxiety (-33%Δ, 95% CI: -53.5, -4.2) and PTSD (-66%Δ, 95% CI: -79.1, -44.6) had lower serum AMH compared with participants without those conditions. When individuals with concurrent PTSD were excluded, the association between anxiety ceased to be statistically significant (26.7%Δ, 95% CI: -17.9, 92.6). <b><i>Conclusion:</i></b> A history of clinically diagnosed anxiety or PTSD was associated with statistically significantly lower AMH levels. This association offers insight into the potential biological mechanisms through which mental health conditions may influence reproductive health.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"354-361"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender Differences in "Making Weight" Behaviors Among U.S. Iraq and Afghan War Veterans: Implications for Future Health. 美国伊拉克和阿富汗战争退伍军人 "减肥 "行为的性别差异:对未来健康的影响》。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2024-11-08 DOI: 10.1089/jwh.2024.0246
Amanda Cary, Kirstie M Herb Neff, Eugenia Buta, Lindsay M Fenn, Christine N Ramsey, Jennifer L Snow, Sally G Haskell, Robin M Masheb
{"title":"Gender Differences in \"Making Weight\" Behaviors Among U.S. Iraq and Afghan War Veterans: Implications for Future Health.","authors":"Amanda Cary, Kirstie M Herb Neff, Eugenia Buta, Lindsay M Fenn, Christine N Ramsey, Jennifer L Snow, Sally G Haskell, Robin M Masheb","doi":"10.1089/jwh.2024.0246","DOIUrl":"10.1089/jwh.2024.0246","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Failure to \"make weight\" carries significant consequences for military personnel including additional training burdens, stigma, possible demotion, or even separation from service. The aim of this study was to examine potential gender differences in, and investigate relationships between, military making weight behavior and obesity, eating pathology, and mental health later in life. <b><i>Method:</i></b> Iraq and Afghanistan war era Veterans (<i>N</i> = 1,126, 51.8% women) completed the Making Weight Inventory (MWI), a measure of making weight behaviors engaged in during military service, and validated measures of eating behavior and mental health. Analyses compared participants who engaged in at least one making weight behavior (MWI+) versus those who did not (MWI-). <b><i>Results:</i></b> Overall, 41% (<i>n</i> = 462) of the sample was categorized as MWI+. The most frequently endorsed making weight behavior was excessive exercise (35.7%). Among those who were MWI+, there was a significantly greater proportion of women (58.2% versus 47.3%, <i>p</i> < 0.001). The MWI+ group had higher rates of obesity (52.4% versus 26.2%) and had significantly higher levels of dietary restraint, emotional eating, food addiction, depression, anxiety, and posttraumatic stress disorder than the MWI- group (<i>p</i>'<i>s</i> < 0.001). <b><i>Conclusions:</i></b> Military making weight behavior was associated with female gender, higher weight, eating pathology, and mental health later in life. Collectively, these findings suggest these factors may place female service members at a disadvantage for career advancement and salary. Efforts to better understand and address extreme making weight efforts in military populations, particularly in female service members and Veterans, are warranted.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"314-321"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association of Menopausal Age with Sex Hormones and Anthropometric Measures Among Postmenopausal Women in the Multi-Ethnic Study of Atherosclerosis Study. 多民族动脉粥样硬化研究中绝经后妇女性激素和人体测量指标与绝经年龄的关系
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2025-01-13 DOI: 10.1089/jwh.2024.0508
Imo A Ebong, Machelle Wilson, Susan B Racette, Duke Appiah, Pamela J Schreiner, Matthew Allison, Karol Watson, Alain G Bertoni, Erin D Michos
{"title":"The Association of Menopausal Age with Sex Hormones and Anthropometric Measures Among Postmenopausal Women in the Multi-Ethnic Study of Atherosclerosis Study.","authors":"Imo A Ebong, Machelle Wilson, Susan B Racette, Duke Appiah, Pamela J Schreiner, Matthew Allison, Karol Watson, Alain G Bertoni, Erin D Michos","doi":"10.1089/jwh.2024.0508","DOIUrl":"10.1089/jwh.2024.0508","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> We investigated associations of menopausal age category with body mass index (BMI), waist circumference, waist-hip ratio, and waist-height ratio. We also explored the moderating effect of anthropometric measures on associations of menopausal age category with prespecified sex hormones: estradiol, dehydroepiandrosterone (DHEA), sex hormone-binding globulin, bioavailable testosterone, and total testosterone-estradiol (T/E) ratio. <b><i>Methods:</i></b> In this cross-sectional study, we included 2,436 postmenopausal women from the Multi-Ethnic Study of Atherosclerosis who had menopausal age, anthropometric, and sex hormone data at baseline. Menopausal age was categorized as <45 years (early menopause), 45-49 years, 50-54 years (referent), and ≥55 years (late menopause). Linear models were used for analysis. <b><i>Results:</i></b> The mean (standard deviation) age was 64.7 (9.2) years. After multivariable adjustment, women who experienced late menopause had higher waist circumference (2.28 cm), waist-hip ratio (0.013 units), and waist-height ratio (0.014 units) but not BMI than those in the referent category. The interaction terms between menopausal age category and anthropometric measures were not significant for prespecified sex hormones (all <i>P<sub>interaction</sub></i> >0.05). When compared with the referent category, T/E ratio was 21% (4.72 - 39.8%) higher among women with late menopause while DHEA levels were 9% (1 - 16%) higher among women who experienced menopause between 45 and 49 years in multivariable adjusted models. <b><i>Conclusion:</i></b> Women with late menopause had higher abdominal adiposity but not generalized adiposity when compared with those who experienced menopause between 50 and 54 years of age. Androgenicity was higher among women who experienced menopause between 45 and 49 years of age and those with late menopause, based on DHEA and T/E ratios, respectively.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"294-306"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Stillbirth Calamity: Reenergized Congressional Relief Efforts. 死产灾难:重新激活国会救济努力。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2025-01-13 DOI: 10.1089/jwh.2024.1012
Eli Y Adashi, Daniel P O'Mahony, Glenn I Cohen
{"title":"The Stillbirth Calamity: Reenergized Congressional Relief Efforts.","authors":"Eli Y Adashi, Daniel P O'Mahony, Glenn I Cohen","doi":"10.1089/jwh.2024.1012","DOIUrl":"10.1089/jwh.2024.1012","url":null,"abstract":"","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"292-293"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contraception Update: A Focus on Safety and Efficacy. 避孕更新:关注安全性和有效性。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2025-01-08 DOI: 10.1089/jwh.2024.1063
Madeline Cohn, Rachel Novik, Pelin Batur
{"title":"Contraception Update: A Focus on Safety and Efficacy.","authors":"Madeline Cohn, Rachel Novik, Pelin Batur","doi":"10.1089/jwh.2024.1063","DOIUrl":"10.1089/jwh.2024.1063","url":null,"abstract":"<p><p>This clinical update serves as a brief summary of recently published and potentially practice changing journal articles. We review recent publications related to contraceptive safety and efficacy. The article discusses updated medical eligibility recommendations, effectiveness of progestin-only pills (including the newly approved over-the-counter pill), safety of estrogen containing contraceptives in those with migraine, topiramate interactions with hormonal contraception, and the use of nonsteroidal antiinflammatory drugs (NSAIDs) with oral emergency contraception to improve efficacy.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"280-283"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the Joint Effects of Epilepsy and Mental Health Conditions on Severe Maternal Morbidity. 检查癫痫和精神健康状况对严重孕产妇发病率的共同影响。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2024-12-04 DOI: 10.1089/jwh.2024.0705
Nicola C Perlman, Jonathan A Mayo, Stephanie A Leonard, Suzan L Carmichael, Kimford J Meador, Thomas F McElrath, Maurice L Druzin, Katherine L Wisner, Danielle M Panelli
{"title":"Examining the Joint Effects of Epilepsy and Mental Health Conditions on Severe Maternal Morbidity.","authors":"Nicola C Perlman, Jonathan A Mayo, Stephanie A Leonard, Suzan L Carmichael, Kimford J Meador, Thomas F McElrath, Maurice L Druzin, Katherine L Wisner, Danielle M Panelli","doi":"10.1089/jwh.2024.0705","DOIUrl":"10.1089/jwh.2024.0705","url":null,"abstract":"<p><p><b><i>Background:</i></b> Mental health conditions and epilepsy frequently coexist and have independently been associated with severe maternal morbidity (SMM). Since little is known about the risks of these conditions when they occur together in pregnancy, we evaluated the associations of mental health conditions, epilepsy, and SMM. <b><i>Methods:</i></b> We conducted a population-based study of births in California between 2007 and 2018. Antenatal epilepsy and mental health conditions (defined as depression, anxiety, posttraumatic stress disorder, and other) were identified using billing codes. We categorized individuals into the following mutually exclusive exposure groups: no epilepsy or mental health conditions (referent), mental health conditions alone, epilepsy alone, or both epilepsy and mental health conditions. Our primary outcome was SMM, defined by the 20-indicator Centers for Disease Control and Prevention Index. We conducted multivariable logistic regression models adjusted for sociodemographic and clinical confounding factors. <b><i>Results:</i></b> In a cohort of 5,275,994 births, SMM occurred more frequently in individuals with mental health conditions alone, epilepsy alone, and both mental health conditions and epilepsy (1.8%, 3.0%, 4.2%, respectively) compared with the referent group (0.8%). The odds of SMM were significantly increased for each exposure group: adjusted odds ratio (aOR) 2.13, 95% confidence interval (CI) 2.05-2.22 for mental health conditions; aOR 3.79, 95% CI 3.45-4.18 for epilepsy; and aOR 4.91, 95% CI 4.01-6.00 for both. <b><i>Conclusion:</i></b> Epilepsy and mental health conditions were independently associated with SMM, and individuals carrying both diagnoses had the highest odds of SMM. Our results highlight the need for awareness of SMM risks in this population.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"e426-e432"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncofertility Research: A Review of the Literature. 肿瘤生育研究:文献综述。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-03-01 Epub Date: 2024-11-18 DOI: 10.1089/jwh.2024.0235
Andreea I Dinicu, Emily H Frisch, Hanna Kim, Camilla Yu, Lindsey Beffa, Elliott G Richards
{"title":"Oncofertility Research: A Review of the Literature.","authors":"Andreea I Dinicu, Emily H Frisch, Hanna Kim, Camilla Yu, Lindsey Beffa, Elliott G Richards","doi":"10.1089/jwh.2024.0235","DOIUrl":"10.1089/jwh.2024.0235","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To examine publication trends pertaining to fertility-sparing management in patients of reproductive age with gynecological malignancies. <b><i>Methods:</i></b> Ovid MEDLINE was used to aggregate all publications on gynecological cancers and fertility between 1946 and 2022. Original research, reviews, case series/reports, and editorials were included. Publication information was extracted from Ovid MEDLINE. Individual authors' subspecialty credentials were individually reviewed and confirmed. Descriptive statistics were generated. <b><i>Results:</i></b> The initial query generated 2,057 publications. Of these, 1,057 (51.4%) publications met search criteria, with the first study being published in 1991 and with 16.6% published in the last 2 years. Only 34 (5.5%) studies were published with collaboration between reproductive endocrinology and infertility (REI) and gynecological oncology physicians in the United States. Gynecological oncologists comprised most senior authors (50.9%), followed by REI specialists (18.6%). Topics of the publications centered on fertility-sparing surgical management (43.1%), medical management of gynecological malignancies (11.3%), and oocyte/ovarian tissue preservation (6.0%). Most publications focused on ovarian malignancies (349, 33.3%), followed by cervical cancer (299, 28.5%), and uterine/endometrial cancer (258, 24.6%). While the number of publications regarding fertility-sparing management has increased over the last 30 years, the majority are retrospective studies and case reports/series. In the last 10 years, only five studies were randomized controlled trials. <b><i>Conclusions:</i></b> There is an urgent need for more prospective research in oncofertility. While fertility care in the setting of gynecological cancer is a collaborative effort between the specialties of gynecological oncology and REI, this partnership is not reflected in the authorship of current literature.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":"e409-e415"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Fertility Forecasts Through 2100: Relevance for Fertility Specialists.
IF 3 3区 医学
Journal of women's health Pub Date : 2025-02-28 DOI: 10.1089/jwh.2025.0090
Alexander M Quaas, Alan S Penzias, Eli Y Adashi
{"title":"Global Fertility Forecasts Through 2100: Relevance for Fertility Specialists.","authors":"Alexander M Quaas, Alan S Penzias, Eli Y Adashi","doi":"10.1089/jwh.2025.0090","DOIUrl":"https://doi.org/10.1089/jwh.2025.0090","url":null,"abstract":"","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Price and Prejudice: Reimbursement of Surgical Care on Male Versus Female Anatomies. 价格与偏见:男性与女性解剖手术的报销。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-02-21 DOI: 10.1089/jwh.2024.0984
Madeline Penn, Donessa Colley, Pratistha Koirala, Louise King, Jocelyn Fitzgerald
{"title":"Price and Prejudice: Reimbursement of Surgical Care on Male Versus Female Anatomies.","authors":"Madeline Penn, Donessa Colley, Pratistha Koirala, Louise King, Jocelyn Fitzgerald","doi":"10.1089/jwh.2024.0984","DOIUrl":"https://doi.org/10.1089/jwh.2024.0984","url":null,"abstract":"<p><p><b><i>Background:</i></b> Gender bias is a pervasive issue in health care, contributing to poorer health outcomes for women compared with men. In the United States, studies have shown a slowly improving, but persistent, disparity exists for gender-specific procedures' relative value units (RVUs). This study aims to build on existing literature and conduct a large-scale analysis examining comparable gender-specific surgical procedures to determine whether there remains a disparity in RVUs/reimbursements for care provided to female patients. <b><i>Methods:</i></b> Using 110 CPT codes, we compared work RVU and reimbursement rates for facility and nonfacility procedures within the 2023 dataset for anatomically similar gender-specific procedures, verified by a group of gynecologists and urologists. We analyzed the procedures over a 20-year period with RVUs from 2003 to 2023 to determine how the difference between the gender-specific procedures was changing over time. We also used the same design and 22 current procedural terminology (CPT) codes as Goff (1997) and Benoit (2015) to compare RVUs between 1997, 2015, and 2023. <b><i>Results:</i></b> For the 55 gender-specific procedures, 41 (75%) had lower RVUs for procedures on female patients in 2023. RVUs for procedures on male patients were 30% higher on average. For facility reimbursement, 35 (64%) were higher for procedures on male patients-with a 25.6% higher reimbursement on average, correlating to an average reimbursement of $75.73 more for male procedures. For nonfacility reimbursements, male procedures were reimbursed 20% higher on average. Between 2003 and 2023, there were no statistically significant improvements in the reimbursement disparities for male versus female procedures, with male procedures consistently having an average RVU 31-34% higher. The disparity narrowed minimally between 1997, 2015, and 2023. <b><i>Conclusion:</i></b> There remain significant disparities between gender-specific procedures, with lower RVUs/reimbursements for procedures on female patients and minimal change over the past three decades. Addressing these disparities is crucial for achieving gender equity in health care and ensuring equally valued medical services.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Latent Class Analysis of Pre-Pregnancy Multimorbidity Patterns in a Delivery Cohort at a Safety-Net Hospital. 安全网医院分娩队列中孕前多病模式的潜类分析。
IF 3 3区 医学
Journal of women's health Pub Date : 2025-02-21 DOI: 10.1089/jwh.2024.0927
Michelle Huezo Garcia, Samantha E Parker, Collette N Ncube, Christina D Yarrington, Martha M Werler
{"title":"A Latent Class Analysis of Pre-Pregnancy Multimorbidity Patterns in a Delivery Cohort at a Safety-Net Hospital.","authors":"Michelle Huezo Garcia, Samantha E Parker, Collette N Ncube, Christina D Yarrington, Martha M Werler","doi":"10.1089/jwh.2024.0927","DOIUrl":"https://doi.org/10.1089/jwh.2024.0927","url":null,"abstract":"<p><p><b><i>Background:</i></b> Multimorbidity affects approximately 1 in 3 adults and is associated with adverse health outcomes. However, there is a paucity of information describing patterns of multimorbidity among the birthing population. The objective of this study was to describe the clustering of pre-pregnancy chronic conditions in the birthing population by age, race and ethnicity, insurance status, and parity using latent class analysis (LCA). <b><i>Study design:</i></b> We conducted a retrospective cohort study of deliveries using medical record data between 2015 and 2019. Multimorbidity was defined as having at least two chronic conditions before the start of the index pregnancy, using adapted versions of obstetric comorbidity indices. The final LCA model was selected based on clinical interpretability and statistical fit. We also compared the distribution of sociodemographic factors across classes. <b><i>Results:</i></b> Of 6,455 deliveries, 1,870 (29%) deliveries were to patients with multimorbidity. LCA resulted in a 3-class model: Class 1 (45% of individuals with multimorbidity) was characterized by mood/anxiety and substance use disorders; class 2 (39%) was defined by body mass index ≥30 kg/m<sup>2</sup> and chronic hypertension; and class 3 (16%) was characterized by reproductive conditions and infertility. Individuals who were <25 years or non-Hispanic White were more frequently in class 1; individuals who were ≥35 years or non-Hispanic Black were disproportionately in class 2. Nulliparas and individuals with private insurance were more frequently in class 3. <b><i>Conclusion:</i></b> Multimorbidity is prevalent in pregnancy and distinct chronic condition clusters vary across sociodemographic sub-groups, demonstrating the need for integrative approaches to periconceptional care for birthing individuals with multimorbidity.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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