MENNAT-ALLAH SAMY EL SAYED, N. Mahana, Ibrahim Rabea, A. Nigm, Osama Mostafa, A. Ashour
{"title":"AMELIORATING EFFECT OF CARICA PAPAYA L. FRUIT EXTRACT ON ENTAMOEBA HISTOLYTICA IN MICE","authors":"MENNAT-ALLAH SAMY EL SAYED, N. Mahana, Ibrahim Rabea, A. Nigm, Osama Mostafa, A. Ashour","doi":"10.21608/jesp.2022.257334","DOIUrl":"https://doi.org/10.21608/jesp.2022.257334","url":null,"abstract":"Entamoeba histolytica is a major public health problem in tropical and subtropical countries. Treatment failure with specific chemotherapy suggested the development of new plant origin therapy. Different parts of Carica papaya Linn. have anti-parasitic agent. The study evaluated the efficacy of C. papaya fruit methanolic and aqueous extracts against Entamoeba histolytica as compared with the used Albendazole ® in experimentally infected mice. Male CD-1 mice were divided into two groups of 50 each; immunocompetent (IC) and dexamethasone immunosuppressed (IS). Each group was subdivided into 5 subgroups, normal, infected and infected treated with crude & pure C. papaya extracts (500mg/kg) or albendazole (200mg/kg). Each mouse was infected orally with 1000 E. histolytica cysts. Six weeks after infection, treatment with pure and crude extracts (3doses/ week) for 3 weeks which started from the 3 rd week after oral administration of dexamethasone, significantly reduced the trophozoites (78.20% & 76.29%, respectively) in IC mice compared to albendazole (88.72% & 81.81%). Serum IgG, IgM, IgA antibody levels and IFN-P < 0.001) increased in treated mice compared to normal ones. Histopathological results showed improvement in the hepatic and intestinal architecture of infected mice treated with papaya extracts and albendazole with various degrees. Results of IS groups were the same as those of IC ones but, with lower levels.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86121031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hager M Helmy, S. Abd-ELrahman, A. Dyab, S. Mohamed
{"title":"PARASITOSIS IN CLARIAS GARIEPINUS AND ITS RELATION TO SOME ENVIRONMENTAL CONDITIONS IN ASSIUT GOVERNORATE, EGYPT","authors":"Hager M Helmy, S. Abd-ELrahman, A. Dyab, S. Mohamed","doi":"10.21608/jesp.2022.257330","DOIUrl":"https://doi.org/10.21608/jesp.2022.257330","url":null,"abstract":"Fish like any other organisms, are susceptible to ecto & endo-parasites, which have a risky impact in aquaculture specially those because skin infection with secondary bacterial infection. This study estimated the parasitic infections in freshwater Catfish ( Clarias gariepinus ) in Assiut Governorate, and evaluated environmental factors affecting them. A total of 100 samples of different sexes and sizes were randomly collected weekly over one year from different localities in Assiut City. The fish were examined parasitological for ecto-parasites and dissected for endo-parasites as well as histopathological examination of muscles. The results showed an overall parasitic rate of 82%. Ecto-parasites were Gyrodactylus , Dactylogrus , Henneguya and Icthyophthirius multifiliis (2%, 8%, 2% & 5%) respectively, while endoparasites were trematode (Orientocreadium batrachoides 26% ), cestode ( Polyochobothrium clarias and Monobothrioides 6% & 21% respectively), nematode ( Paracamallanus spp. 12%), encysted metacercaria (66%) and protozoa ( Entamoeba spp. 15%). The variation between the parasitic number length, weight, and sex seasonally were statistically analyzed.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75784539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saheb Nematollahi, B. Hajimohammadi, G. Eslami, M. Ehrampoush, A. Tafti
{"title":"PREVALENCE AND RISK FACTORS OF TOXOPLASMOSIS AMONG WOMEN OF REPRODUCTIVE AGE, SOUTHWESTERN IRAN","authors":"Saheb Nematollahi, B. Hajimohammadi, G. Eslami, M. Ehrampoush, A. Tafti","doi":"10.21608/jesp.2022.257707","DOIUrl":"https://doi.org/10.21608/jesp.2022.257707","url":null,"abstract":"Toxoplasma gondii is an obligate intracellular parasite that has a worldwide prevalence. This infection can lead to severe problems during pregnancy, including miscarriage, and fetal develop-mental retardation. This study assessed the seroprevalence of toxoplasmosis in women of reproductive age in Dehdasht, Iran. Blood samples were collected from 300 women referred to Health Center between Febr-uary and July 2020. Serum was separated and the anti- Toxoplasma IgG & IgM were assessed by using the ELISA. Also, all women were administered a questionnaire to record demographic and risk factors data such as age, residence, education level, marital status, contact with cats, consumption of raw vegetables, methods of cooking meat, occupation, raw liver consumption, contact with soil, and raw egg consumption. SPSS software v.23 and Chi-square test used for statistical analyses. The results showed that 32/300 (10.6%) women were seropositive for anti- Toxoplasma IgG, but negative for anti- Toxoplasma IgM. There was a significant relationship between the prevalence of toxoplasmosis with age, accommodation, contact with cats, and methods of washing vegetables, number of serving vegetables per day, method of cooking meat, occupation, liver consumption, and contact with soil. There was no significant relationship between toxoplasmosis with marital status, consumption of raw vegetables, number of servings of meat, and consumption of eggs.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79377346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Younis, A. Elkholy, G. Rashed, Azza S. Elghareeb, N. Youssef
{"title":"EFFECT OF THYMOL EXTRACT ON TRICHINELLOSIS COMPARED TO ALBENDAZOLE AMONG EXPERIMENTALLY INFECTED MICE","authors":"M. Younis, A. Elkholy, G. Rashed, Azza S. Elghareeb, N. Youssef","doi":"10.21608/jesp.2022.257459","DOIUrl":"https://doi.org/10.21608/jesp.2022.257459","url":null,"abstract":",","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86839512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PATHOGENS DIARRHEA IN CHILDREN, RISKS AND TREATMENT","authors":"S. Ahmad, A. Morsy","doi":"10.21608/jesp.2022.257457","DOIUrl":"https://doi.org/10.21608/jesp.2022.257457","url":null,"abstract":"Diarrhea is the condition of having at least three (or more than in normal individual), loose, liquid, or watery bowel movements each day, or for few days resulting in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behavior by decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclu-sively breastfed, however, are normal. Frequent passing of formed stools is neither diarrhea, nor is the passing of loose, \"pasty\" stools by breastfed babies. Diarrhea is usually a symptom of an infection in intestinal tract caused by many bacterial, viral and parasitic organisms. Infection is spread through contaminated food or water, or from person-to-person as a result of poor hygiene.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83396621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AN OVERVIEW NEEDLE STICKS OR SHARPS RELATED INJURIES AND BLOOD-BORNE PATHOGENS","authors":"H. Hussein, L. Megahed, Reham EL SADANY, T. Morsy","doi":"10.21608/jesp.2022.257711","DOIUrl":"https://doi.org/10.21608/jesp.2022.257711","url":null,"abstract":"Blood-borne pathogens are infectious microorganisms in human blood that can cause disease in humans. These pathogens include, not limited to, hepatitis B (HBV), hepatitis C (HCV), human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (ADIS), but also extended to other viruses, bacterial and protozoa infectious diseases. Needle-sticks and other sharps-related injuries may expose workers to blood-borne pathogens. ACGME core competencies: medical knowledge, practice-based learning and improvement, professionali-sm needle stick injury (NSI) became a major issue and most of the research focuses on Nurses, Doctors and other health care workers, but at the same time nursing students in clinical duties are at high risk. This is a short selected overview of nosocomial blood-borne pathogens transmitted to health care workers by injuries.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77236422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Morsy, Mamdouh M M El Bahnasawy, Rafaat Abdelrahman
{"title":"AN OVERVIEW ON BLOOD DONORS MEDICAL HISTORY AND RISK OF DISEASES TRANSMISSION: WITH SPECIAL REFERENCE TO EGYPT","authors":"T. Morsy, Mamdouh M M El Bahnasawy, Rafaat Abdelrahman","doi":"10.21608/jesp.2022.257453","DOIUrl":"https://doi.org/10.21608/jesp.2022.257453","url":null,"abstract":"A blood transfusion provides blood or blood components to a save patient life who lost blood due to an injury, during surgery or have certain medical conditions that affect blood or its components. Before transfusion, a nurse must check blood pressure, pulse and temperature, make sure the donor blood type is a match for patient blood type and make sure that the sup-plied blood is the product ordered by your doctor and is labeled with patient name. During transfusion, she must recheck blood pressure and pulse after 15 minutes, and recheck patient blood pressure and pulse at the transfusion end. But, viruses, parasites and specific bacteria can be transmitted in donated blood through a transfusion to the recipient. This reviewed the commonest infectious diseases to prevent spread of such diseases by blood transfusion.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87105396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reham A. Mostafa, M. Elarousy, M. Shalaby, A. Abdelaal, S. Mahmoud, M. Badawi, S. Ismail, Reham K. Nahnoush
{"title":"CLOVE OIL OR COMBINED WITH PRAZIQUANTEL DOWN REGULATED TGF-Β1 AND REVERSED FIBROGENIC DYNAMIC PROGRESSION CAUSED BY CHRONIC SCHISTOSOMIASIS MANSONI IN MICE","authors":"Reham A. Mostafa, M. Elarousy, M. Shalaby, A. Abdelaal, S. Mahmoud, M. Badawi, S. Ismail, Reham K. Nahnoush","doi":"10.21608/jesp.2022.257335","DOIUrl":"https://doi.org/10.21608/jesp.2022.257335","url":null,"abstract":"The most serious form of chronic schistosomiasis is the life-threatening hepatosplenic disease, accompanied by severe periportal fibrosis, a permanent condition once established. Reversion of ration and the process of scar formation is ensued. In the current work, clove oil alone and combined with PZQ were used to investigate their anti-fibrotic effect on hepatic fibrosis resulted from acute and chronic schistosomiasis mansoni in mice. To determine the state of hepatic fibroblasts, local expression of TGF- 1, a chief profibrogenic molecule was quantified using digital real-time image analysis and compared with the conventional parasitological and histopathological analysis. PZQ monotherapy caused a significant reduction in ova count, granuloma number and size. Local expression of TGF-gave better data as compared to acute and chronic infected treated mice (11.91±2.53- 20.34±3.05 vs. 7.51±2.11-11.23±2.23) with clove alone treatment & 4.95±1.95-7.51±1.92 in combined therapy (p=0.0000)), indicated low potential in achieving liver tissue repair. Significant drop in TGF- 1 expression with clove oil treatment, especially when combined with PZQ, indicated anti-fibrotic potentiality and good impact on liver cells proceeded towards regeneration supported by such drop. A significant positive correlation between mean TGF- 1 values and mean granuloma parameters in number and size of different infected groups (R² = 0.680 & 0.988, respectively in acute infection, 0.363 & 0.505 respectively, in chronic phase of infection, P value <0.05).","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"3527 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86657561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Nasr, Abeer Said AL- ANTABLY, M. Ismail, Marwa M. Zein, Shimaa ABDEL AAL
{"title":"PARASITOLOGICAL STUDIES AMONG EGYPTIAN PATIENTS ATTENDED DIAGNOSTIC & RESEARCH UNIT OF PARASITIC DISEASES, KASR AL-AINY TEACHING HOSPITALS: A FIVE-YEAR RETROSPECTIVE STUDY","authors":"D. Nasr, Abeer Said AL- ANTABLY, M. Ismail, Marwa M. Zein, Shimaa ABDEL AAL","doi":"10.21608/jesp.2022.257458","DOIUrl":"https://doi.org/10.21608/jesp.2022.257458","url":null,"abstract":"This is a retrospective study on recorded parasitic infections for in- and outpatients attended Diagnostic & Research Unit of Parasitology, Medical Parasitology Department, Kasr Al-Ainy Teaching Hospitals from 2017 to 2021. A total of 10557 samples were examined for parasites, Helicobacter pylori antigen detection and occult blood in stool. Stool samples ( 1%) were infected with 15 species of intestinal parasites. These were Blastocystis hominis (13%), Giardia lamblia (3%), Entamoeba histolytica (3%), Entamoeba coli (1%), mixed infections (1.6%), H. pylori co-infection (2%), and occult blood with parasites (0.3%). Male to female infection ratio was 50.3% to 49.7%. The highest prevalence season of infection was autumn (31.5%). But, all these results were statistically non-significant (p>0.05).","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"121 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91408590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. AlBalakosy, M. Hussein, M. Khalil, H. Hussein, M. Abdallah, Safaa R Askar
{"title":"EPIDEMIOLOGY OF FEVER OF UNKNOWN ORIGIN (FUO) AT IMBABA FEVER HOSPITAL, GIZA GOVERNORATE, EGYPT","authors":"A. AlBalakosy, M. Hussein, M. Khalil, H. Hussein, M. Abdallah, Safaa R Askar","doi":"10.21608/jesp.2022.257329","DOIUrl":"https://doi.org/10.21608/jesp.2022.257329","url":null,"abstract":"Fever of unknown origin (FUO) is caused by various diseases, and infections were the most frequent causes of FUO. The progress of the diagnostic techniques may have changed the breakdown of diseases causing FUO. This prospective study aimed to explore the clinical spectrum of fevers of undetermined origin (FUO) among adult patients treated at the Imbaba Fever Hospital from June 2018 to May 2019. All Egyptian patients who met the FUO criteria and were hospitalized during this period were followed up until they were diagnosed. They were 350 of whom186 females (53.1%) and 164 males (46.9%), with ages ranged from 18 to 82 years (32.77±14.4). The commonest FUO cause was infections (72%), followed by autoimmune diseases (20%), malignancies accounted (2%) of the total with the diagnosis unknown in 4.6%. Brucellosis and pneumonia were considered major causes of infections.","PeriodicalId":17289,"journal":{"name":"Journal of the Egyptian Society of Parasitology","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82743061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}