Journal of the Chinese Medical Association最新文献

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Winners of the 2022 honor awards for excellence at the annual meeting of the Chinese Medical Association-Taipei: Part II. 中华医学会台北分会2022年年会优秀奖得奖者名单(下)。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-07-27 DOI: 10.1097/JCMA.0000000000000971
Peng-Hui Wang, Teh-Ia Huo
{"title":"Winners of the 2022 honor awards for excellence at the annual meeting of the Chinese Medical Association-Taipei: Part II.","authors":"Peng-Hui Wang, Teh-Ia Huo","doi":"10.1097/JCMA.0000000000000971","DOIUrl":"10.1097/JCMA.0000000000000971","url":null,"abstract":"","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the detection accuracy of SARS-CoV-2 rapid antigen test in children and adolescents: An updated meta-analysis. 评估儿童和青少年SARS-CoV-2快速抗原检测的准确性:一项最新的荟萃分析
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-09-08 DOI: 10.1097/JCMA.0000000000000987
Cheng-Chieh Chen, Mei-Hui Lee, Shih-Yen Chen, Shou-Cheng Lu, Chyi-Huey Bai, Yu-Ling Ko, Chien-Ying Wang, Yuan-Hung Wang
{"title":"Assessment of the detection accuracy of SARS-CoV-2 rapid antigen test in children and adolescents: An updated meta-analysis.","authors":"Cheng-Chieh Chen, Mei-Hui Lee, Shih-Yen Chen, Shou-Cheng Lu, Chyi-Huey Bai, Yu-Ling Ko, Chien-Ying Wang, Yuan-Hung Wang","doi":"10.1097/JCMA.0000000000000987","DOIUrl":"10.1097/JCMA.0000000000000987","url":null,"abstract":"<p><strong>Background: </strong>Real-time and appropriate antigen tests play a pivotal role in preventing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. However, a previous meta-analysis reported that the antigen test had lower sensitivity for the detection of SARS-CoV-2 in children. To provide a comprehensive evaluation of diagnostic efficiency, we performed an updated meta-analysis to assess the detection accuracy of SARS-CoV-2 antigen tests stratified by days after symptom onset and specimen type in children and adolescents.</p><p><strong>Methods: </strong>We comprehensively searched for appropriate studies in the PubMed, Embase, and Cochrane Library databases. Studies on the diagnostic accuracy of antigen tests for SARS-CoV-2 in children and adolescents were included. The relevant data of the included studies were extracted to construct a 2 × 2 table on a per-patient basis. The overall sensitivity and specificity of the SARS-CoV-2 antigen tests were estimated using a bivariate random-effects model.</p><p><strong>Results: </strong>Seventeen studies enrolling 10 912 patients were included in the present meta-analysis. For the detection accuracy of SARS-CoV-2 antigen tests, the meta-analysis generated a pooled sensitivity of 77.9% (95% confidence interval [CI]: 67.3%-85.8%) and a pooled specificity of 99.6% (95% CI: 98.9%-99.8%). The subgroup analysis of studies that examined antigen tests in symptomatic participants ≦7 days after symptom onset generated a pooled sensitivity of 79.4% (95% CI: 47.6%-94.2%) and a pooled specificity of 99.4% (95% CI: 98.2%-99.8%). Another subgroup analysis of studies that evaluated nasal swab specimens demonstrated a pooled sensitivity of 80.1% (95% CI: 65.0%-89.7%) and a pooled specificity of 98.5% (95% CI: 97.3%-9.2%).</p><p><strong>Conclusion: </strong>Our findings demonstrated that the antigen test performed using nasal swab specimens exhibited high sensitivity for the detection of SARS-CoV-2 within 7 days after symptom onset. Therefore, antigen testing using nasal swabs may be effective in blocking SARS-CoV-2 transmission in children.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10186555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Donor lymphocyte infusion for prophylaxis and treatment of relapse in pediatric hematologic malignancies after allogeneic hematopoietic stem cell transplant. 供体淋巴细胞输注预防和治疗儿童异基因造血干细胞移植后恶性血液病复发。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-09-12 DOI: 10.1097/JCMA.0000000000000992
Ming-Hsin Hou, Chih-Ying Lee, Cheng-Yin Ho, Ting-Yen Yu, Giun-Yi Hung, Fang-Liang Huang, Tzeon-Jye Chiou, Chun-Yu Liu, Hsiu-Ju Yen
{"title":"Donor lymphocyte infusion for prophylaxis and treatment of relapse in pediatric hematologic malignancies after allogeneic hematopoietic stem cell transplant.","authors":"Ming-Hsin Hou, Chih-Ying Lee, Cheng-Yin Ho, Ting-Yen Yu, Giun-Yi Hung, Fang-Liang Huang, Tzeon-Jye Chiou, Chun-Yu Liu, Hsiu-Ju Yen","doi":"10.1097/JCMA.0000000000000992","DOIUrl":"10.1097/JCMA.0000000000000992","url":null,"abstract":"<p><strong>Background: </strong>Donor lymphocyte infusion (DLI) is effective for managing patients with hematologic malignancies after allogeneic hematopoietic stem cell transplant (HSCT). However, few studies have explored its optimal use in pediatric populations. Herein, we report our single-center experiences of DLI and factors for predicting its outcomes.</p><p><strong>Methods: </strong>This retrospective study included pediatric patients who had received DLI (between June 1998 and December 2022) after allogeneic HSCT. Data regarding patient characteristics, preemptive DLI disease status, and DLI characteristics were collected. The primary outcomes were overall survival (OS), event-free survival (EFS), and graft-vs-host-disease (GVHD) development.</p><p><strong>Results: </strong>The study cohort comprised 17 patients with acute leukemia, 3 with chronic leukemia, and 3 with lymphoma. Prophylactic, preemptive, and therapeutic DLI were used in seven, seven, and nine patients, respectively. Patients' median age and DLI dose were 9 years and 4.6 × 10 7 CD3 + cells/kg, respectively. The 5-year OS, EFS, and nonrelapse mortality were 43.5%, 38.3%, and 13.3%, respectively. Approximately 39% of the patients developed grade III or IV acute GVHD, whereas moderate/severe chronic GVHD (cGVHD) occurred in 30% of the evaluable patients. Patients' disease status before HSCT ( p = 0.009) and DLI ( p = 0.018) were the key factors influencing EFS. The implementation of a dose escalation schedule was associated with a marginal reduction in the risk of moderate/severe cGVHD ( p = 0.051). A DLI dose of ≥5 × 10 7 CD3 + cells/kg was significantly associated with a high moderate to severe cGVHD risk ( p = 0.002) and reduced OS ( p = 0.089).</p><p><strong>Conclusion: </strong>Patients' disease status before HSCT and DLI may help predict EFS. The use of DLI as a prophylactic and preemptive modality leads to a favorable 5-year EFS. To safely deliver DLI in children, clinicians must maintain vigilant monitoring and prepare patients in advance when escalating the dose to ≥5 × 10 7 CD3 + cells/kg.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10213905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of early clinical exposure and interprofessional collaboration: Commonalities between Taiwan and Japan in the field of community medicine. 早期临床接触与跨专业合作的重要性:台湾与日本在社区医学领域的共同点。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-09-15 DOI: 10.1097/JCMA.0000000000000996
Manabu Murakami, Akiko Takeuchi, Shigeki Jin, Kotaro Matoba
{"title":"The importance of early clinical exposure and interprofessional collaboration: Commonalities between Taiwan and Japan in the field of community medicine.","authors":"Manabu Murakami, Akiko Takeuchi, Shigeki Jin, Kotaro Matoba","doi":"10.1097/JCMA.0000000000000996","DOIUrl":"10.1097/JCMA.0000000000000996","url":null,"abstract":"","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10260164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between serum CA-125 level and recurrence in surgical stage I endometrial cancer patients. 手术期子宫内膜癌患者血清CA-125水平与复发的关系。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-08-29 DOI: 10.1097/JCMA.0000000000000985
Hua-Hsi Wu, Hung-Tse Chou, Jen-Yu Tseng, I-San Chan, Yi-Jen Chen
{"title":"The relationship between serum CA-125 level and recurrence in surgical stage I endometrial cancer patients.","authors":"Hua-Hsi Wu, Hung-Tse Chou, Jen-Yu Tseng, I-San Chan, Yi-Jen Chen","doi":"10.1097/JCMA.0000000000000985","DOIUrl":"10.1097/JCMA.0000000000000985","url":null,"abstract":"<p><strong>Background: </strong>The majority of patients diagnosed with early stage endometrial cancer have a favorable prognosis; however, approximately 10% to 15% experience a recurrence. Therefore, the aim of the present study was to evaluate whether postoperative carbohydrate antigen 125 (CA-125) levels could be used to predict recurrence and recurrence-free survival (RFS) in patients with surgical stage I endometrial cancer.</p><p><strong>Methods: </strong>We enrolled a total of 518 patients with stage I endometrial cancer who underwent surgical treatment between January 2010 and March 2019. Serum CA-125 levels were measured prior to surgery, as well as 6 to 12 months after surgery. Subsequently, the correlations between the CA-125 levels, cancer recurrence, and RFS were analyzed.</p><p><strong>Results: </strong>Although the preoperative CA-125 level was not associated with the risk of cancer recurrence, the postoperative CA-125 level was found to be the only independent predictor of recurrence in both univariate and multivariate analyses. Additionally, we found that a postoperative CA-125 cutoff value of 13.75 U/mL yielded the best sensitivity and specificity for predicting cancer recurrence. Patients with a postoperative CA-125 level ≥13.75 U/mL, and those with a level <13.75 U/mL, had a median time to recurrence and a 5-year RFS rate of 35.5 vs 50.5 months and 84.7 vs 94.4%, respectively. Additionally, postoperative CA-125 levels were not found to be correlated with preoperative levels.</p><p><strong>Conclusion: </strong>In patients with stage I endometrial cancer, a postoperative CA-125 level ≥13.75 U/mL was found to be significantly correlated with a higher recurrence rate, as well as a shorter RFS. Therefore, obtaining a follow-up CA-125 level within 6 to 12 months after staging surgery may be a promising noninvasive biomarker for predicting recurrence.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10109944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with the efficacy of mature oocyte production after dual-trigger controlled ovarian stimulation using a GnRH antagonist protocol. 使用GnRH拮抗剂方案双触发控制卵巢刺激后成熟卵母细胞产生功效的相关因素。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-11-01 Epub Date: 2023-09-04 DOI: 10.1097/JCMA.0000000000000989
Geok Huey New, Wen-Bin Wu, Hsuan-Ting Chen, Jun-Jie Lin, Tsung-Hsuan Lai
{"title":"Factors associated with the efficacy of mature oocyte production after dual-trigger controlled ovarian stimulation using a GnRH antagonist protocol.","authors":"Geok Huey New, Wen-Bin Wu, Hsuan-Ting Chen, Jun-Jie Lin, Tsung-Hsuan Lai","doi":"10.1097/JCMA.0000000000000989","DOIUrl":"10.1097/JCMA.0000000000000989","url":null,"abstract":"<p><strong>Background: </strong>The number of mature oocytes retrieved plays a significant role in determining embryo development and pregnancy outcomes of in vitro fertilization (IVF). However, studies investigating factors predictive of the efficacy of mature oocyte production (EMOP) after dual-trigger controlled ovarian stimulation (COS) are rare. This study aims to identify key predictors of EMOP during dual-trigger COS with a gonadotropin-releasing hormone (GnRH) antagonist protocol for IVF.</p><p><strong>Methods: </strong>This retrospective cohort study included 359 first-time IVF patients undergoing dual-trigger COS with a GnRH antagonist protocol. EMOP was defined as the ratio of metaphase II (MII) oocyte count to antral follicle count (AFC). Based on EMOP results, patients were divided into two groups: group A (EMOP <70%; n = 232) and group B (EMOP ≥70%; n = 127).</p><p><strong>Results: </strong>Multivariate logistic regression analysis revealed that day-2 follicle-stimulating hormone (FSH), stimulation duration, and total oocyte count were the most significant predictors of EMOP ( p < 0.05; odds ratios: 1.637, 3.400, and 1.530, respectively). Receiver operating characteristic analysis demonstrated that total oocyte count <9.5 (area under the curve [AUC], 0.782; sensitivity, 76.2%; specificity, 69.2%; p < 0.001) and stimulation duration <9.5 days (AUC, 0.725; sensitivity, 63.5%; specificity, 66.7%; p < 0.001) significantly predicted EMOP <70%. Stimulation duration combined with total oocyte count exhibited the highest power in predicting EMOP <70% (AUC, 0.767; sensitivity, 92.3%; specificity, 42.4%).</p><p><strong>Conclusion: </strong>Stimulation duration combined with total oocyte count was identified as the most important factor associated with the EMOP during dual-trigger COS in IVF using a GnRH antagonist protocol.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The outcomes and prognostic factors of patients with hepatocellular carcinoma and Child-Turcotte-Pugh class B. 肝细胞癌和Child-Turcotte-Pugh B级患者的预后因素。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-10-01 Epub Date: 2023-08-04 DOI: 10.1097/JCMA.0000000000000975
Chia-Chu Fu, Yu-Jen Chen, Chien-Wei Su, Cheng-Yi Wei, Chi-Jen Chu, Pei-Chang Lee, Teh-Ia Huo, Yi-Hsiang Huang, Hui-Chun Huang, Jaw-Ching Wu, Ming-Chih Hou
{"title":"The outcomes and prognostic factors of patients with hepatocellular carcinoma and Child-Turcotte-Pugh class B.","authors":"Chia-Chu Fu,&nbsp;Yu-Jen Chen,&nbsp;Chien-Wei Su,&nbsp;Cheng-Yi Wei,&nbsp;Chi-Jen Chu,&nbsp;Pei-Chang Lee,&nbsp;Teh-Ia Huo,&nbsp;Yi-Hsiang Huang,&nbsp;Hui-Chun Huang,&nbsp;Jaw-Ching Wu,&nbsp;Ming-Chih Hou","doi":"10.1097/JCMA.0000000000000975","DOIUrl":"10.1097/JCMA.0000000000000975","url":null,"abstract":"<p><strong>Background: </strong>The Child-Turcotte-Pugh (CTP) score is widely used for assessing the liver's functional reserve in patients with advanced chronic liver disease (ACLD) and hepatocellular carcinoma (HCC). This study aims to explore the outcomes of patients with HCC and CTP class B and to investigate the prognostic accuracy of prediction models for ACLD in these patients.</p><p><strong>Methods: </strong>We retrospectively enrolled 1143 patients with HCC and CTP class B between 2007 and 2022. We divided the patients into three subgroups based on their CTP scores: CTP-B7, CTP-B8, and CTP-B9. We compared the corrected Akaike information criterion among each mortality prediction model, including the CTP score, albumin-bilirubin (ALBI) score, modified ALBI score, the model for end-stage liver disease (MELD), and MELD 3.0.</p><p><strong>Results: </strong>Among the enrolled patients, 576 (50.3%) were in the CTP-B7 group, 363 (31.8%) were in the CTP-B8 group, and 204 (17.9%) were in the CTP-B9 group. After a median follow-up of 4.6 months (interquartile range IQR 1.8-17.2 months), 963 patients died, and the 5-year overall survival (OS) rate was 11.4%. The 5-year OS rates were 11.6%, 13.6%, and 8.3% in the CTP-B7, CTP-B8, and CTP-B9 groups, respectively. Patients in the CTP-B7 group and CTP-B8 group had comparable OS ( p = 0.089), both of which were better than those in the CTP-B9 group ( p < 0.001). Furthermore, the MELD 3.0 score had the lowest corrected akaike information criteria value and provided a more accurate mortality prediction than the MELD score, ALBI grade, modified ALBI grade, and CTP score.</p><p><strong>Conclusion: </strong>Patients in the CTP-B7 and CTP-B8 groups had comparable OS, both of which were better than those in the CTP-B9 group. Moreover, MELD 3.0 provided the most accurate mortality prediction in patients with HCC and CTP class B.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10308874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery for severe mitral regurgitation: The etiology matters. 外科治疗严重二尖瓣反流:病因很重要。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-10-01 Epub Date: 2023-08-10 DOI: 10.1097/JCMA.0000000000000977
Yi-Lin Tsai, Ching-Wei Lee, Wei-Ming Huang, Hao-Min Cheng, Wen-Chung Yu, Chen-Huan Chen, Shih-Hsien Sung
{"title":"Surgery for severe mitral regurgitation: The etiology matters.","authors":"Yi-Lin Tsai,&nbsp;Ching-Wei Lee,&nbsp;Wei-Ming Huang,&nbsp;Hao-Min Cheng,&nbsp;Wen-Chung Yu,&nbsp;Chen-Huan Chen,&nbsp;Shih-Hsien Sung","doi":"10.1097/JCMA.0000000000000977","DOIUrl":"10.1097/JCMA.0000000000000977","url":null,"abstract":"Background: While surgery has been the standard treatment for patients with severe primary mitral regurgitation (PMR), the role of surgery for severe secondary mitral regurgitation (SMR) remained debated. We therefore investigated the prognostic differences of surgery for patients with either severe PMR or SMR. Methods: Subjects hospitalized for heart failure were enrolled from 2002 to 2012. The severity of MR was assessed by continuity equation, and an effective regurgitant orifice area of ≥40 mm2 was defined as severe. Long-term survival was then identified by the National Death Registry. Results: A total of 1143 subjects (66.4 ± 16.6 years, 65% men, and 59.7% PMR) with severe MR were analyzed. Compared with PMR, patients with SMR were older, had more comorbidities, greater left atrial and ventricular diameter, and less left ventricular ejection fraction (all p < 0.05). While 47.8% of PMR patients received mitral valve surgery, only 6.9% of SMR patients did. Surgical intervention crudely was associated with 54% reduction of all-cause mortality in PMR (hazard ratio, 0.46; 95% confident interval, 0.32-0.67), and 48% in the subpopulation with SMR (0.52, 0.30-0.91). Propensity score matching analysis demonstrated the survival benefits of mitral valve surgery was observed in patients with PMR (log rank p = 0.024), but not with SMR. Among the unoperated subjects, age, renal function, and right ventricular systolic pressure were common risk factors of mortality, regardless of MR etiology. Conclusion: Mitral valve surgery for patients with heart failure and severe MR was associated with better survival in patients with PMR, but not in those with SMR.","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10021088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in insulin resistance, glucose effectiveness, and first and second phases of insulin secretion in women aged 45-60 years old in Taiwan. 台湾45-60岁女性胰岛素抵抗、血糖有效性和胰岛素分泌第一和第二阶段的变化。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-10-01 Epub Date: 2023-08-10 DOI: 10.1097/JCMA.0000000000000976
Chen-Yu Wang, Chung-Ze Wu, Fang-Yu Chen, Dee Pei, Li-Ying Huang
{"title":"Changes in insulin resistance, glucose effectiveness, and first and second phases of insulin secretion in women aged 45-60 years old in Taiwan.","authors":"Chen-Yu Wang,&nbsp;Chung-Ze Wu,&nbsp;Fang-Yu Chen,&nbsp;Dee Pei,&nbsp;Li-Ying Huang","doi":"10.1097/JCMA.0000000000000976","DOIUrl":"10.1097/JCMA.0000000000000976","url":null,"abstract":"<p><strong>Background: </strong>In women after menopause, the incidence of diabetes mellitus increases. Increased insulin resistance (IR), decreased glucose effectiveness (GE), and the first and second phases of insulin secretion (FPIS and SPIS), are the four most important factors that trigger glucose intolerance and diabetes (diabetogenic factor [DF]). In the cross-sectional study, we enrolled nondiabetic women between the ages of 45 and 60 years to observe the changes in DFs during the perimenopausal period and to elucidate the underlying mechanisms of diabetes in menopausal women.</p><p><strong>Methods: </strong>We randomly enrolled 4194 women who underwent health checkups. Using demographic and biochemical data, IR, FPIS, SPIS, and GE were calculated using previously published equations. The relationship between the DFs and age was evaluated using a simple correlation.</p><p><strong>Results: </strong>Body mass index, blood pressure, fasting plasma glucose, low-density lipoprotein cholesterol, triglyceride, and SPIS were higher, and GE was lower in older women (≥52 years old). A significant decrease in GE and increased SPIS were observed with age. However, no changes were observed in IR or FPIS.</p><p><strong>Conclusion: </strong>The IR and FPIS did not change during perimenopause. Increased SPIS may compensate for the decrease in GE, which is probably one of the reasons for the higher incidence of diabetes in menopausal women.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10338662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Bibliometric analysis of the top 100 most-cited articles on video laryngoscope from 2011 to 2022. 2011年至2022年视频喉镜最受引用的100篇文章的文献计量分析。
IF 3 4区 医学
Journal of the Chinese Medical Association Pub Date : 2023-10-01 Epub Date: 2023-09-08 DOI: 10.1097/JCMA.0000000000000981
Chih-Chung Shiao, Jui-Teng Wu, Ya-Chun Chu, Yu-Hsuan Tang, Lawrence Huang, Hsien-Yung Lai
{"title":"Bibliometric analysis of the top 100 most-cited articles on video laryngoscope from 2011 to 2022.","authors":"Chih-Chung Shiao,&nbsp;Jui-Teng Wu,&nbsp;Ya-Chun Chu,&nbsp;Yu-Hsuan Tang,&nbsp;Lawrence Huang,&nbsp;Hsien-Yung Lai","doi":"10.1097/JCMA.0000000000000981","DOIUrl":"10.1097/JCMA.0000000000000981","url":null,"abstract":"<p><strong>Background: </strong>The popularity of video laryngoscope (VL) has increased rapidly since its introduction in the late 1990s. However, a comprehensive overview of VLs evolution and impact is lacking, which merits further investigation.</p><p><strong>Methods: </strong>We conducted a bibliometric analysis of the top 100 most-cited articles on VL (Top100VL) published between 2011 and 2022 and retrieved from the PubMed and Web of Science databases. Using social network analysis, we identified the subject terms and subject categories of the Top100VL and compared their citation counts across individual subject terms and categories via one-way analysis of variance (ANOVA). Then, we employed the Medical Query Expert software to assess the practical applications of VL.</p><p><strong>Results: </strong>The Top100VL included 65 subjects across nine subject categories, with \"anesthesiology\" being the most frequently represented category and \"coronavirus infections\" with the highest impact factor. The citation counts inferred by subject categories significantly correlated with the actual citation counts (Pearson's R = 0.4; p < 0.01). For enhanced visualization, we employed network visualization and Sankey diagrams to display the article characteristics. We highlighted the clinical advantages of VL, including its usefulness in difficult intubations, wider angle of view, and management of pediatric emergencies, as well as its teaching benefits, such as facilitating training programs and a lower learning curve.</p><p><strong>Conclusion: </strong>By using bibliometric analysis and natural language processing methods, we effectively summarized the applications of VL in both clinical and teaching settings, particularly in reducing the risk of cross-infection during the Coronavirus Disease 2019 pandemic.</p>","PeriodicalId":17251,"journal":{"name":"Journal of the Chinese Medical Association","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10185017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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