Journal of the Advanced Practitioner in Oncology最新文献_第4页

Clinical Utility of the 31-Gene Expression Profile Test on the Management of Cutaneous Melanoma by Nurse Practitioners and Physician Assistants 31 基因表达谱检验对执业护士和助理医师管理皮肤黑色素瘤的临床实用性

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.3

Renata Block, MMS, PA-C, Deborah Patterson, MMS, PA-C, Jennifer J. Siegel, PhD, Brian Martin, PhD, Ann P. Quick, PhD, Jillian Hunt, MSN, APRN, FNP-C, AOCNP

{"title":"Clinical Utility of the 31-Gene Expression Profile Test on the Management of Cutaneous Melanoma by Nurse Practitioners and Physician Assistants","authors":"Renata Block, MMS, PA-C, Deborah Patterson, MMS, PA-C, Jennifer J. Siegel, PhD, Brian Martin, PhD, Ann P. Quick, PhD, Jillian Hunt, MSN, APRN, FNP-C, AOCNP","doi":"10.6004/jadpro.2023.14.7.3","DOIUrl":"https://doi.org/10.6004/jadpro.2023.14.7.3","url":null,"abstract":"Objective: The 31-gene expression profile (31-GEP) can predict the risk of recurrence and metastasis in cutaneous melanoma (CM). We assessed the viewpoints and use of 31-GEP testing by physician assistants (PAs) and nurse practitioners (NPs) for patients with CM. Methods: NPs and PAs (n = 369) completed an 18-question online survey about their viewpoints and use of the 31-GEP risk-stratification test. Results: Most practitioners (n = 334, 90.5%) felt prognostic testing improved patient care and would recommend the 31-GEP to a colleague (n = 333, 90.2%) or a friend or family member (n = 289, 78.3%) who was diagnosed with CM. The 31-GEP test was used by 176 respondents in the preceding 12 months (53%). Among users of the 31-GEP test, 78% stated that the results would impact follow-up schedule and referral, 66% overall treatment decisions, 62% sentinel lymph node biopsy recommendations, and 50% surveillance imaging. In thin tumors (″ 1 mm), 82% of 31-GEP users and 44% of nonusers stated that the 31-GEP results would impact their treatment plan decisions. Conclusion: The 31-GEP test significantly impacts treatment plans in CM, particularly for thin and stage I melanomas. Importantly, even nonusers stated that 31-GEP test results would impact treatment plans as well as recommendations to a friend or family member.","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139299158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of the Advanced Practitioner in Clinical Research 高级医师在临床研究中的作用

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.14

Christa Marie Braun-Inglis, DNP, APRN, FNP-BC, AOCNP, Brianna Hoffner, MSN, ANP-BC, AOCNP, FAPO, Lisa Kottschade, APRN, MSN, CNP, FAPO, Erin Pierce, MSN, APRN, FNP-C, Sandra Kurtin, PhD, ANP-BC, AOCN, FAPO

引用次数: 0

Mitigating Burnout: Transition to a Condensed Workweek for Advanced Practice Providers in Infectious Diseases 减轻职业倦怠：传染病高级医疗人员向紧凑工作周的过渡

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.8

Shannon Holloway, PA-C, Kelly McConn, PA-C, Roy Borchardt, PA-C, PhD, Victor E. Mulanovich, MD, Javier A. Adachi, MD

{"title":"Mitigating Burnout: Transition to a Condensed Workweek for Advanced Practice Providers in Infectious Diseases","authors":"Shannon Holloway, PA-C, Kelly McConn, PA-C, Roy Borchardt, PA-C, PhD, Victor E. Mulanovich, MD, Javier A. Adachi, MD","doi":"10.6004/jadpro.2023.14.7.8","DOIUrl":"https://doi.org/10.6004/jadpro.2023.14.7.8","url":null,"abstract":"Burnout among health-care workers is highly prevalent and profoundly impacts the quality of patient care. In addition to affecting patient safety, burnout results in higher staff turnover, revenue deficits due to decreased productivity, financial risk, and diminished organization viability because of the impact on quality of care, patient satisfaction, and safety. Culmination of external and internal stressors in health-care worker populations is associated with a higher probability of burnout and workers who reported perceived low workplace flexibility. In addition, workplace flexibility is associated with reduced odds of experiencing burnout. Workplace flexibility plays a critical role in potentially reducing the occurrence of burnout in the health-care worker population. Individually focused solutions are important to mitigate burnout, however, comprehensive organizational change ensures durable and sustainable solutions. There is a correlation between a positive employee outlook and reduced stress when there is a perceived level of control over one’s work schedule. The goal of this article is to showcase the process of a successful implementation of a condensed work schedule for an advanced practice provider workforce in infectious diseases in response to burnout and workload shifts. This chronicles the steps of design, rationale, procuring buy-in by stakeholders, and operational implementation of the new schedules. Advanced practice provider satisfaction and burnout were measured by periodic surveys at timepoints along the way.","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139297805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

APSHO Oncology/Hematology Advanced Practitioner Compensation Survey APSHO 肿瘤学/血液学高级执业医师薪酬调查

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.15

Wendy Vogel, MSN, FNP, AOCNP, FAPO, Yi Lisa Hwa, APRN, DNP, CNP, FAPO, Lisa Kottschade, APRN, MSN, CNP, FAPO, Megan May, PharmD, BCOP, FAPO, FHOPA

引用次数: 0

Capecitabine for Salvage Treatment of Patients With Heavily Pretreated Human Papillomavirus–Associated Oropharynx Cancer With Distant Metastases 卡培他滨用于重度预处理人乳头状瘤病毒相关口咽癌远处转移患者的挽救治疗

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.2

Anna C. Cooper, PA-C, Casey A. Fazer, PA-C, Ashish V. Chintakuntlawar, MBBS, PhD, Harry E. Fuentes Bayne, MD, MS, Patrick W. McGarrah, MD, Katharine A. R. Price

{"title":"Capecitabine for Salvage Treatment of Patients With Heavily Pretreated Human Papillomavirus–Associated Oropharynx Cancer With Distant Metastases","authors":"Anna C. Cooper, PA-C, Casey A. Fazer, PA-C, Ashish V. Chintakuntlawar, MBBS, PhD, Harry E. Fuentes Bayne, MD, MS, Patrick W. McGarrah, MD, Katharine A. R. Price","doi":"10.6004/jadpro.2023.14.7.2","DOIUrl":"https://doi.org/10.6004/jadpro.2023.14.7.2","url":null,"abstract":"Background: Patients with metastatic human papillomavirus–associated oropharyngeal cancer (HPV-OPC) have a median overall survival exceeding 2 years and are often candidates for multiple lines of palliative therapy. With the approval of immunotherapy as first-line treatment, salvage therapeutic options are limited. We describe our experience using capecitabine as salvage therapy for patients with recurrent or metastatic (R/M) HPV-OPC. Methods: We performed a retrospective study of patients with R/M HPV-OPC with distant metastatic disease. Eligible patients were identified from a medical oncology clinical database. Demographic and clinical data were abstracted from the medical record. Survival probabilities were estimated with the Kaplan-Meier method. Results: 10 patients were identified. Sites of metastatic disease included lung, liver, mediastinal lymph nodes, bone, abdominal lymph nodes, and soft tissue. Most patients received capecitabine as fourth-line treatment. The median duration from start of capecitabine therapy until death was 10.5 months. Best treatment response was as follows: partial responses (PR) were seen in 4 of 10 (40%), stable disease (SD) in 3 of 10 (30%), and progressive disease (PD) in 2 of 10 (20%). The clinical benefit rate (CR + PR + SD) was 70%. Reasons for discontinuation included disease progression (n = 8) and side effects (n = 2). One patient notably had prolonged benefit from capecitabine and continued to be on treatment for 34 months total. Conclusions: Capecitabine is a potential salvage treatment for heavily pretreated patients with R/M HPV-OPC, with some patients experiencing prolonged response. Clinical or molecular predictors of response would be helpful to identify patients likely to benefit; a larger prospective study would be useful to confirm efficacy in this patient population.","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced Practitioners as Agents of Change: Leveraging Quality Improvement to Improve Practice 高级医师是变革的推动者：利用质量改进改善实践

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.13

Sandra Kurtin, PhD, ANP-BC, AOCN, FAPO, Andrea Edwards, PA-C, Heather Koniarczyk, MSN, APRN-CNP, AOCNP, Camille Petraitis, DNP, FNP-BC, Lisa Nodzon, PhD, APRN, AOCNP, Nicole Deline, MSN, APRN, FNP-C, AOCNP, Tajuana Bradley, FNP-BC, Megan May, PharmD, BCOP, FAPO, FHOPA, Molly Thompson-Coffey, Jessica Tamasi, Wendy Vogel, MSN, FNP, AOCNP, FAPO

{"title":"Advanced Practitioners as Agents of Change: Leveraging Quality Improvement to Improve Practice","authors":"Sandra Kurtin, PhD, ANP-BC, AOCN, FAPO, Andrea Edwards, PA-C, Heather Koniarczyk, MSN, APRN-CNP, AOCNP, Camille Petraitis, DNP, FNP-BC, Lisa Nodzon, PhD, APRN, AOCNP, Nicole Deline, MSN, APRN, FNP-C, AOCNP, Tajuana Bradley, FNP-BC, Megan May, PharmD, BCOP, FAPO, FHOPA, Molly Thompson-Coffey, Jessica Tamasi, Wendy Vogel, MSN, FNP, AOCNP, FAPO","doi":"10.6004/jadpro.2023.14.7.13","DOIUrl":"https://doi.org/10.6004/jadpro.2023.14.7.13","url":null,"abstract":"Scientific innovation in hematology and oncology is constant and increasingly complex, requiring individual clinicians and institutions to effectively integrate standards of care across the diverse hematology and oncology landscape into practice. Effective integration of evolving diagnostics, risk models, new therapeutics and novel treatment strategies, and practice regulation requirements requires ongoing practice improvement efforts and an infrastructure to implement change. Advanced practitioners (APs) are poised to serve as agents of change based on their clinical presence, clinical expertise, familiarity with critical members of the interdisciplinary team, communication skills, and ability to envision and actualize optimized workflows. Through practice analysis, workflow optimization, role delineation, and effective utilization and tailoring of documentation in the electronic health record, APs can lead implementation strategies to improve patient outcomes. In this article, we will review the essential role APs play as agents of change to implement best practice models using quality improvement (QI) processes. The principles of QI as a strategy for practice improvement, including strategies and tools for successful practice analysis, workflow optimization, outcome analysis, implementation, and sustainability of change, will be reviewed. Proposed elements of a QI and practice integration toolkit for APs and a series of QI exemplars, including an Advanced Practitioner Society for Hematology and Oncology (APSHO)-led QI initiative and AP-led QI initiatives, will be summarized.","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139304564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Fasting on Patients With Cancer: An Integrative Review 禁食对癌症患者的影响：综合评论

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.5

Samantha Thompson, MPH, MCHS, PA-C, Lydia T. Madsen, PhD, RN, AOCNS, FNAP, Angela Bazzell, DNP, APRN, FNP-BC, AOCNP

{"title":"Impact of Fasting on Patients With Cancer: An Integrative Review","authors":"Samantha Thompson, MPH, MCHS, PA-C, Lydia T. Madsen, PhD, RN, AOCNS, FNAP, Angela Bazzell, DNP, APRN, FNP-BC, AOCNP","doi":"10.6004/jadpro.2023.14.7.5","DOIUrl":"https://doi.org/10.6004/jadpro.2023.14.7.5","url":null,"abstract":"Background: Patients with cancer often pursue nutrition as an avenue to positively impact their care management and disease outcomes. Nutritional interventions are increasing in popularity, especially intermittent fasting as an adjunct to chemotherapy. However, limited research is available on the impact of intermittent fasting on patients with cancer. Methods: A comprehensive literature search was conducted using Ovid MEDLINE, Ovid EMBASE, and CINAHL databases. Results: 514 articles were identified from the three databases. Seven studies remained after applying inclusion and exclusion criteria. The seven studies included in this review examined fasting compliance, malnutrition, therapy side effects, endocrine parameters, quality of life measures, and cancer outcomes. Data suggest overall good compliance, no malnutrition, minimal side effects, a trend toward improved endocrine parameters, unchanged quality of life (QOL), and mixed results for cancer outcomes. Conclusion: Intermittent fasting as an adjunct to chemotherapy in normal-weight patients with cancer has potential as a safe, tolerable, and feasible nutritional intervention that could positively impact treatment outcomes and QOL. Large-scale randomized controlled trials are needed to validate these findings and determine what future role intermittent fasting may play in cancer management.","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"2009 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139300872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced Practitioners in Hematology and Oncology: A Call to Action 血液学和肿瘤学高级医师：行动呼吁

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.9

Sandra Kurtin, PhD, ANP-BC, AOCN, FAPO

引用次数: 0

When Germline Genetic Testing Results Are Unclear: Highlighting Variants of Uncertain Significance 当种系遗传检测结果不明确时：强调意义不确定的变异基因

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.7

Patricia Kelly, DNP, APRN, CNS, AGN-BC, AOCN, Suzanne Mahon, DNS, RN, AOCN, AGN-BC, FAAN, Patricia Friend, PhD, APRN-CNS, AOCNS, AGN-BC

引用次数: 0

JADPRO Live 2023: Shaping the Future of Oncology JADPRO Live 2023：塑造肿瘤学的未来

Journal of the Advanced Practitioner in Oncology Pub Date : 2023-11-01 DOI: 10.6004/jadpro.2023.14.7.1

Beth Faiman, PhD, MSN, APRN-BC, AOCN, BMTCN, FAAN, FAPO

引用次数: 0