Journal of research in health sciences最新文献

{"title":"Factors Associated with Smoking Cessation in Underdeveloped Areas of Indonesia.","authors":"Muhamad Arif Musoddaq, Dwi Hapsari Tjandrarini, Felly Philipus Senewe, Alfons Maryono Letelay, Hadi Ashar, Budi Setyawati, Ning Sulistiyowati, Maxwell Landri Vers Malakauseya, Christiana Rialine Titaley","doi":"10.34172/jrhs.11518","DOIUrl":"10.34172/jrhs.11518","url":null,"abstract":"<p><strong>Background: </strong>Indonesia has one of the highest smoking rates globally. Smoking cessation is critical for reducing smoking-related diseases, particularly in areas with limited healthcare access. This study explored factors associated with smoking cessation in underdeveloped areas of Indonesia. <b>Study Design:</b> This study was conducted using a cross-sectional design.</p><p><strong>Methods: </strong>Data were obtained from the 2018 Indonesia Basic Health Research survey. We used information from 16,989 ever-smokers aged 10 years or older living in underdeveloped areas of Indonesia. Binary logistic regression analyses were performed to identify factors associated with smoking cessation.</p><p><strong>Results: </strong>Overall, 8.1% of ever-smokers in underdeveloped areas of Indonesia had stopped smoking cigarettes at the time of the survey. Increased odds of smoking cessation were were observed among respondents living in urban areas (aOR=1.50, 95% CI: 1.13-2.00), females (aOR=2.59, 95% CI: 1.85-3.62), aged over 45 years (aOR=2.60, 95% CI: 2.13-3.17), the unemployed or students (aOR=1.60, 95% CI: 1.24-2.01), and heads of households (aOR=1.84, 95% CI: 1.45-2.32). Non-daily smokers (aOR=6.84, 95% CI: 5.68-8.24) and those who started smoking before age 18 (aOR=1.34, 95% CI: 1.10-1.62) were more likely to have quit smoking.</p><p><strong>Conclusion: </strong>Public health interventions should focus on supporting younger populations, informal workers, and daily smokers in rural areas to improve cessation rates.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00671"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of Anxiety and Depression Among Youth in India: Findings from a Large-Scale Population-Based Cross-sectional Study.","authors":"Nidhi Saraswat, Pradeep Banandur, Gautham Melur Sukumar, Shalin Lily Giboy, Arvind Banavaram Anniappan","doi":"10.34172/jrhs.11330","DOIUrl":"10.34172/jrhs.11330","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and depression are major public health concerns due to their high prevalence and associated suffering, dysfunction, and socioeconomic impact, particularly among young individuals. Identifying factors associated with anxiety and depression is crucial for the prevention and promotion of mental health in youth. The present analysis aims to identify factors associated with anxiety and depression among youth, based on a youth health survey undertaken in Kolar district, India. <b>Study Design:</b> This study employed a cross-sectional design.</p><p><strong>Methods: </strong>A secondary data analysis was conducted using data from the Kolar Youth Health Survey, which collected data on various health-related behaviors and conditions from 5,072 youth (aged 15-30 years). Anxiety and depression were screened using standardized tools (GAD-7 and PHQ-9, respectively). Multivariable logistic regression was conducted to identify associated factors. The model's goodness of fit was evaluated using the Hosmer-Lemeshow test and the area under the curve.</p><p><strong>Results: </strong>Socio-demographic characteristics (marital status, taluka, age), self-reported diagnosed health conditions, sleep issues, suicide and non-suicidal self-harm, tobacco dependence, time spent on phone/computer, family relationships (loving/affectionate relationships vs. serious conflicts), friendships, belief in God, and injury (physical violence, road traffic injuries) were significantly associated with anxiety and/or depression among youth in the study area.</p><p><strong>Conclusion: </strong>Selected sociodemographic characteristics, health-impacting behaviors, and health issues were found to be significantly associated with anxiety and/or depression among youth. Considering these risk factors will enable health care providers and policymakers to develop and implement tailored interventions.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00668"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trend Analysis of Suicide Mortality and Years of Life Lost from 2012 to 2023 in Khuzestan Province, Iran: A Cross-sectional Study.","authors":"Habibollah Azarbakhsh, Seyed Parsa Dehghani, Elahe Piraie, Mahdiyeh Rashedi, Reza Davasaz-Irani, Fatemeh Rezaei","doi":"10.34172/jrhs.11469","DOIUrl":"10.34172/jrhs.11469","url":null,"abstract":"<p><strong>Background: </strong>The present study was designed to assess the mortality rate and years of life lost due to suicide in Khuzestan province . <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>In this study, data on all deaths caused by suicide in Khuzestan province were obtained from the population-based Electronic Death Registration System (EDRS). Crude and age-standardized suicide mortality rates (ASR) were calculated based on gender and year of death over the study period. Subsequently, the number of years of life lost (YLL) was calculated based on age and gender. Joinpoint regression analysis was used to examine the trends in crude mortality rates, age-standardized rates (ASRs), and YLL rates.</p><p><strong>Results: </strong>During the study years, 1904 suicide deaths occurred in Khuzestan province . Of these deaths, 1157 (60.8%) occurred in men. The highest number of deaths in both genders occurred due to hanging. According to the joinpoint regression, the 12-year trend of YLL rate due to premature mortality was stable. The average annual percentage change (AAPC) was -0.4% (95% CI -4.5 to 7.9, <i>P</i>=0.986) for males, and it was 2.4% (95% CI -1.6 to 7.5, <i>P</i>=0.222) for females. There were 1 joinpoint and 2 time periods for males (2012-2014 (non-significant decreases) and 2014-2023 (significant increases)), and there were 1 joinpoint and 2 time periods for females (2012-2016 (significant decreases) and 2016-2023 (significant increases)).</p><p><strong>Conclusion: </strong>The findings revealed a significant increase in age-standardized mortality rate among women and a stable trend among men, and a slight rise in crude mortality rate in men. To address these concerns, it is recommended that targeted region-specific prevention programs be strengthened.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00675"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Health Literacy and General Health in Women With Gestational Diabetes: A Cross-sectional Study.","authors":"Yasaman Rajabi Basir, Sara Alipour, Farzaneh Esna-Ashari, Shiva Borzouei","doi":"10.34172/jrhs.11438","DOIUrl":"10.34172/jrhs.11438","url":null,"abstract":"<p><strong>Background: </strong>Health literacy includes cognitive and social skills that enable individuals to understand and use health information effectively. In addition, it significantly influences health outcomes in society. Women with gestational diabetes mellitus (GDM) often have low health literacy and need better education. Therefore, this study explored the link between health literacy and general health in these women. <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>This study involved 200 women with GDM referred to the Diabetes Clinic in Hamadan, Iran. The participants were selected through consecutive sampling, and the required data were collected using self-reported questionnaires, a health literacy questionnaire, and a general health questionnaire. The obtained data were analyzed using SPSS with a 95% confidence level.</p><p><strong>Results: </strong>The mean age of women was 29.63 years, and the mean±standard deviation (SD) of health literacy score was 77.41±16.44. Further, the mean±SD of the general health questionnaire score was 21.02±6.01. There was a positive correlation between health literacy and general health (<i>P</i><0.001), as well as between health literacy and education (<i>P</i><0.05). Moreover, a positive correlation was found between general health and education (<i>P</i><0.05). Eventually, a significant negative correlation was observed between age and general health (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Health literacy plays an essential role in managing GD and promoting general health for pregnant women. This subsequently leads to reduced postpartum complications for the mother and baby, as well as reduced healthcare costs.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00674"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Access to Sanitation Services: How Maternal Education Moderates Childhood Diarrhea Risk in Indonesia's Multilevel Context.","authors":"Ika Dharmayanti, Dwi Hapsari Tjandrarini, Rina Marina, Khadijah Azhar, Basuki Rachmat, Zahra Zahra, Tities Puspita, Sri Irianti, Doni Lasut, Andre Yunianto","doi":"10.34172/jrhs.11228","DOIUrl":"10.34172/jrhs.11228","url":null,"abstract":"<p><strong>Background: </strong>Despite long-standing efforts to improve water, sanitation, and hygiene (WASH) infrastructure in Indonesia, childhood diarrhea remains a pressing public health concern. This study focuses on the gaps between infrastructure and health equity by examining the intertwined effects of child, household, and environmental factors on the risk of diarrhea. <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>In this study, data from the 2017 Indonesia Demographic and Health Survey (IDHS) were analysed using a multilevel logistic regression model. The survey included 16632 children, with children nested within households and households within a cluster (environment). All child, household, and environmental-level variables were included as fixed effects. Cross-level interactions were examined with sanitation, maternal education, and household wealth in terms of the prevalence of diarrhea.</p><p><strong>Results: </strong>Children aged 12-23 months (AOR=4.24; 95% CI: 3.23, 5.43), those with low birth weight [AOR=1.33 (95% CI: 1.04-1.70)], and those born to mothers with low education (AOR=1.74; 95% CI: 1.25, 2.44) had significantly higher odds of experiencing diarrhea. A significant interaction revealed that the impact of poor sanitation on children with less-educated mothers (AOR=1.68; 95% CI: 1.19, 2.37) and among educated mothers in children from low-income households (AOR=1.6; 95% CI: 1.12, 2.29) remained elevated. Children in non-Java-Bali regions also had persistently higher rates of diarrhea.</p><p><strong>Conclusion: </strong>Access to sanitation is insufficient to guarantee health equity. Maternal education plays a crucial moderating role in translating infrastructure into better health outcomes. To accomplish Sustainable Development Goals 6 and 10, integrated equity-focused sanitation programs, including poverty reduction and maternal empowerment, are of great importance.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00670"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Opium Consumption, Diabetes, and Hypertension Among Male Participants in the Tabari Cohort Population: A Cross-sectional Study.","authors":"Keyvan Heydari, Motahareh Kheradmand, Somayyeh Ahmadnezhad, Mahmood Moosazadeh","doi":"10.34172/jrhs.11343","DOIUrl":"10.34172/jrhs.11343","url":null,"abstract":"<p><strong>Background: </strong>Opium consumption is a prevalent health concern in Iran, with conflicting evidence regarding its association with chronic conditions such as diabetes mellitus (DM) and hypertension (HTN).The present study aimed to investigate the association between opium consumption and the risk of diabetes mellitus (DM) and hypertension (HTN) among male participants aged 35-70 years in the Tabari Cohort Study (TCS). <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>This study examined male participants from the TCS. Blood samples were collected after a 12-hour fasting period. HTN and DM were defined based on blood pressure (BP) measurements, history of diagnosis, and use of antihypertensive or glucose-lowering medications. The obtained data were analyzed using chi-squared and independent t-tests. A multivariate logistic regression analysis was used to adjust for potential confounders.</p><p><strong>Results: </strong>The study examined 4,149 male participants, with a mean fasting blood sugar (FBS) of 110.34±3 3.89 mg/dL, systolic BP of 115.70±13.60 mm Hg, and diastolic BP of 73.87±7.77 mm Hg. No significant difference was found in the frequency of HTN and DM among participants who consumed opium compared to those who did not consume it (<i>P</i>=0.588 and <i>P</i>=0.705, respectively). However, FBS levels were significantly higher among opium users (110.77±34.14 vs. 107.73±21.19, <i>P</i>=0.048). Multivariable regression analysis revealed no significant change in the risk of developing HTN (odds ratio [OR]: 1.06, 95% confidence interval [CI]: 0.82, 1.35, <i>P</i>=0.667) and DM (OR: 1.22, 95% CI: 1.57, <i>P</i>=0.116) among opium users.</p><p><strong>Conclusion: </strong>The findings of this study demonstrate no significant difference in the likelihood of developing DM and HTN between opium users and non-users.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00673"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns, Causes, and Mortality Trends of Road Traffic Accidents in Hamedan Province, Iran: A Spatiotemporal Epidemiological Analysis (2011-2024).","authors":"Ebrahim Jalili, Salman Khazaei, Mahdi Khazaei, Sanaz Omidi","doi":"10.34172/jrhs.11510","DOIUrl":"10.34172/jrhs.11510","url":null,"abstract":"<p><strong>Background: </strong>Road traffic accidents (RTAs) are a major cause of death, especially in developing countries. This study analyzed RTA patterns and trends in Hamadan province, Iran, from 2011 to 2024. <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>Data on 6,488 road traffic fatalities, excluding non-road transport deaths, were obtained from the Forensic Medicine Organization. Demographics, injury type, location, and mode of transport were analyzed. Then, spatial clustering was performed using the K-prototype algorithm, with cluster quality assessed via the Silhouette Score. Finally, mortality trends were forecasted using the Prophet model with 95% prediction intervals and evaluated using RMSE, MAE, MASE, and MAPE.</p><p><strong>Results: </strong>The mean age of victims was 49 ± 21 years, with most deaths observed in the 15-44 age group. Most victims were male (75%), urban residents (60%), married (69%), and had not completed secondary education (41%). Fatalities mainly occurred at the scene (48%) or en route to the hospital (43%), with head/face injuries and hemorrhage as the leading causes. Spatial analysis revealed three clusters, with Famenin having the highest mortality (73.7 per 100,000). Mortality was projected to decline from 18.27 (16.01, 20.55) in 2025 to 9.57 (7.37, 11.69) in 2028, rising slightly to 13.94 (11.83, 16.17) in 2029.</p><p><strong>Conclusion: </strong>Overall, the findings emphasize the need for targeted regional interventions (e.g., road safety education, enhanced emergency services, and infrastructure upgrades) to reduce RTA mortality in the high-risk areas of Hamedan Province.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00672"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual Alcohol Consumption Depending on Regional Living Conditions: Results of a Russian Nationwide Study Based on 2012-2022 Data.","authors":"Sergey A Maksimov, Svetlana A Shalnova, Yulia A Balanova, Asia E Imaeva, Marina B Kotova, Daria A Kashtanova, Anna V Kontsevaya, Oksana M Drapkina","doi":"10.34172/jrhs.11352","DOIUrl":"10.34172/jrhs.11352","url":null,"abstract":"<p><strong>Background: </strong>Individual alcohol consumption depends on living conditions at different territorial and environmental levels. This study examined the influence of regional living conditions on individual alcohol consumption based on the results of a large Russian nationwide study (2012-2022). <b>Study Design:</b> A cross-sectional multicenter observational study.</p><p><strong>Methods: </strong>Individual data from three stages of the Russian nationwide study, including the Epidemiology of Cardiovascular Diseases and Their Risk Factors in the Regions of the Russian Federation (ESSE-RF1) (2012-2014), ESSE-RF2 (2017-2018), and ESSE-RF3 (2020-2022), were used for investigation. The study samples included 53,902 men and women aged 25-74 years from 31 regions. Individual data were combined with the annual values of four regional indices that characterize economic, demographic, social, and industrial environmental conditions. The analyzed outcomes included any alcohol consumption and binge drinking.</p><p><strong>Results: </strong>The industrial development of regions was associated with an increased likelihood of any alcohol consumption (odds ratio [OR]: 1.66, 95% confidence interval [CI]: 1.59-1.72) and binge drinking (OR: 1.31, CI: 1.22-1.40). Improved economic (OR: 0.75, 95% CI: 0.72-0.78), demographic (OR: 0.73, 95% CI: 0.71-0.76), and social (OR: 0.55, 95% CI: 0.53-0.56) living conditions exhibited inverse associations with any alcohol consumption. Similar inverse associations of binge drinking were noted with the economic (OR: 0.84, 95% CI: 0.76-0.92), demographic (OR: 0.91, 95% CI: 0.85-0.98), and social (OR: 0.78, 95% CI: 0.73-0.82) indices.</p><p><strong>Conclusion: </strong>In general, our findings revealed the associations of alcohol consumption and binge drinking with the regional characteristics of living conditions.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"26 1","pages":"e00669"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145714847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substance Misuse Pattern and Sexual Risk Behavior among Street Adolescents in Central Java, Indonesia.","authors":"Zahroh Shaluhiyah, Bagoes Widjanarko, Syamsulhuda Budi Mustofa, Priyadi Nugraha","doi":"10.34172/jrhs.11317","DOIUrl":"10.34172/jrhs.11317","url":null,"abstract":"<p><strong>Background: </strong>Substance use is common among street adolescents and is strongly associated with sexual risk behavior as well as vulnerability to sexually transmitted infections. Therefore, this study was conducted to explore patterns of substance use and the association with sexual risk behavior among street adolescents in Central Java, Indonesia. <b>Study Design:</b> A cross-sectional study.</p><p><strong>Methods: </strong>In this cross-sectional study, data were collected from 248 street adolescents through face-to-face interviews using a validated questionnaire. Data analysis was conducted using descriptive statistics, chi-square tests, and multivariate logistic regression in SPSS version 25.0.</p><p><strong>Results: </strong>More than a quarter of adolescents reported engaging in high-risk sexual behavior. Heavy smoking, alcohol use, and frequent exposure to pornography were prevalent. Alcohol use was significantly associated with sexual risk behavior, with adjusted odds ratios ranging from 3.26 to 4.38 across Models I-III. Furthermore, frequent exposure to pornography showed a strong association, with odds ratios of 3.02 (Model I) and 4.20 (Model II). These associations remained significant after adjusting for demographic and behavioral variables.</p><p><strong>Conclusion: </strong>Substance use, particularly alcohol consumption, and frequent exposure to pornography were significantly associated with sexual risk behavior among street adolescents. Therefore, interventions should be developed to address the specific needs of this population. Adolescents engaged in high-risk behavior, such as substance use and sexual risk behavior, required high attention and specific treatment options.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"25 4","pages":"e00661"},"PeriodicalIF":1.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12555716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145390586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic Burden of Tuberculosis in Iran: A Nationwide Analysis by Drug Resistance and Cost Components.","authors":"Masoud Arefnezhad, Mahshid Nasehi, Aliakbar Fazaeli, Saeed Sharafi, Rajabali Daroudi","doi":"10.34172/jrhs.11215","DOIUrl":"10.34172/jrhs.11215","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) remains a significant global health crisis, regaining its status as the leading cause of death in 2023. Quantifying its economic burden is essential for crafting effective public health strategies. This study aimed to estimate the economic burden of TB in Iran. <b>Study Design:</b> This study employed a cross-sectional design.</p><p><strong>Methods: </strong>A prevalence-based approach was used to estimate the economic burden of TB in Iran, accounting for cost variations across TB types and cost categories. Costs were categorized as direct medical, direct non-medical, and indirect, and were calculated for suspected TB patients as well as for those with drug-sensitive TB, multidrug-resistant TB, and extensively drug-resistant TB. Data were extracted from various sources, including the National Tuberculosis Registration System, national TB diagnosis and treatment guidelines in Iran, official medical service tariffs, and previous studies.</p><p><strong>Results: </strong>Of 210,544 individuals screened, 7,221 were diagnosed with TB, of whom 81.0% had pulmonary TB and 19.0% had extrapulmonary TB. Drug-sensitive TB accounted for 99.4% of cases, multidrug-resistant TB 0.6%, and extensively drug-resistant TB 0.0%. Diagnostic costs represented 48.0% of the total economic burden (approximately Int'l$4.71 million), while post-diagnosis costs totaled Int'l$5.15 million. Overall, economic burden, including all diagnostic and treatment expenses, amounted to approximately Int'l$9.86 million.</p><p><strong>Conclusion: </strong>This study underscores the significant economic burden of TB in Iran, encompassing both pre-diagnosis and post-diagnosis expenses, with direct medical costs representing the largest component. Effective healthcare strategies and comprehensive public health approaches are crucial to reducing these costs and improving patient outcomes.</p>","PeriodicalId":17164,"journal":{"name":"Journal of research in health sciences","volume":"25 4","pages":"e00665"},"PeriodicalIF":1.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12555715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145390597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}