Journal of the American College of Surgeons最新文献_第9页

Appendectomy vs Right Hemicolectomy for Pediatric Neuroendocrine Tumor of the Appendix in a National Cohort: A Call to Further Decrease Colectomy. 儿童阑尾神经内分泌肿瘤的阑尾切除术与右半结肠切除术在国家队列中的比较：呼吁进一步减少结肠切除术。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-05 DOI: 10.1097/XCS.0000000000001435

Swathi R Raikot, Donald Dean Potter, Courtney N Day, Hallbera Gudmundsdottir, Wendy A Allen-Rhoades, Elizabeth B Habermann, Stephanie F Polites

{"title":"Appendectomy vs Right Hemicolectomy for Pediatric Neuroendocrine Tumor of the Appendix in a National Cohort: A Call to Further Decrease Colectomy.","authors":"Swathi R Raikot, Donald Dean Potter, Courtney N Day, Hallbera Gudmundsdottir, Wendy A Allen-Rhoades, Elizabeth B Habermann, Stephanie F Polites","doi":"10.1097/XCS.0000000000001435","DOIUrl":"https://doi.org/10.1097/XCS.0000000000001435","url":null,"abstract":"Background: Children continue to undergo right hemicolectomy (RHC) for neuroendocrine tumors (NET) of the appendix based on adult guidelines. Appendectomy alone is recommended for the pediatric population; however, there are no data on safety of this approach in the setting of positive margins. This study aimed to determine the association between tumor characteristics and survival in a national cohort, hypothesizing that survival would be excellent despite high-risk features including positive margins on appendectomy.Study design: Patients aged ≤ 18 years with NET of the appendix were identified in the National Cancer Database from 2004 to 2022 using ICD-O-3 codes. Characteristics of patients who underwent definitive appendectomy vs RHC were compared using Chi-square tests. Five-year survival was determined for appendectomy patients with and without high-risk size, margin, and lymph node (LN) features.Results: Of 1,339 patients, 1,156 (86%) underwent appendectomy and 183 (14%) RHC. Median age in both groups was 15 (13, 17) years. Patients who underwent RHC had larger tumors (24% vs 4% >2 cm, p<.001), more lymphovascular invasion (31% vs 10%, p<.001), and were more likely to undergo LN assessment (82% vs 10%, p<.001) with a higher LN positivity rate (31% vs 16%, p=.006). There was no difference in margins status (p=0.76). The 5- and 10-year survival was excellent regardless of tumor characteristics for patients overall (99.9% and 99.4%, respectively) and for those who underwent definitive appendectomy (99.9% and 99.2%).Conclusion: These data further support appendectomy as definitive management for children with appendiceal NET. Additional resection does not confer a survival benefit even in the setting of positive margins.","PeriodicalId":17140,"journal":{"name":"Journal of the American College of Surgeons","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indocyanine Green Is Not Necessary If the Elements of Calot's Triangle Are Easy to Identify. 如果卡洛特三角形的元素很容易识别，就不需要吲哚菁绿。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-05 DOI: 10.1097/XCS.0000000000001429

Adriana Toro, Alessandro Terrasi, Ivan Lo Iacona, Isidoro Di Carlo

引用次数: 0

Advancing the Optimization of Indocyanine Green Administration Strategies for Fluorescence Cholangiography In reply to Toro and colleagues. 推进荧光胆管造影吲哚菁绿色给药策略的优化答Toro等。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-05 DOI: 10.1097/XCS.0000000000001428

Wenjun Lin, Haisu Tao, Jian Yang

引用次数: 0

Metformin Use and Risk of Breast Cancer-Related Lymphedema: A Retrospective Analysis. 二甲双胍的使用和乳腺癌相关淋巴水肿的风险：回顾性分析。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-05 DOI: 10.1097/XCS.0000000000001434

Jonathan Rubin, Bracha Pollack, Janet Coleman-Belin, Adana-Christine Campbell, Arielle Roberts, Benjamin D Wagner, Raghu P Kataru, Lillian Boe, Andrea V Barrio, Babak J Mehrara

{"title":"Metformin Use and Risk of Breast Cancer-Related Lymphedema: A Retrospective Analysis.","authors":"Jonathan Rubin, Bracha Pollack, Janet Coleman-Belin, Adana-Christine Campbell, Arielle Roberts, Benjamin D Wagner, Raghu P Kataru, Lillian Boe, Andrea V Barrio, Babak J Mehrara","doi":"10.1097/XCS.0000000000001434","DOIUrl":"https://doi.org/10.1097/XCS.0000000000001434","url":null,"abstract":"Background: Over 30% of breast cancer patients develop lymphedema following axillary lymph node dissection (ALND), significantly impacting their quality of life. Comorbid conditions like diabetes mellitus (DM), which contribute to endothelial dysfunction and inflammation, may also affect lymphatic endothelium. Preclinical studies suggest that metformin, a common DM treatment, may reduce lymphedema risk.Study design: We conducted a retrospective analysis of breast cancer patients at Memorial Sloan Kettering Cancer Center who underwent ALND from January 2004 through December 2022 (4,882 patients overall). We stratified patients according to if they were diagnosed with DM at the time of surgery, and if so, if they were receiving metformin. We also conducted univariable and multivariable analyses of patient demographics for the overall cohort and the metformin vs no-metformin DM subgroups.Results: Of the 407 patients with diabetes at the time of ALND, 250 (61%) were receiving metformin and 157 (39%) were not. While having diabetes at the time of ALND was a significant risk factor for lymphedema on univariable (HR: 1.38; 95% CI: 1.14, 1.66; P < .001) and multivariable (HR: 1.55; 95% CI: 1.19, 2.02; P = .001) analysis, metformin treatment was associated with a significant decrease in lymphedema risk (univariable HR: 0.66; 95% CI: 0.46, 0.94; P = .023; multivariable HR: 0.62; 95% CI: 0.43, 0.89; P = .010).Conclusion: Diabetic breast cancer patients have a significantly increased risk of developing lymphedema after ALND; however, those using metformin at the time of surgery had a lower incidence compared to non-users.","PeriodicalId":17140,"journal":{"name":"Journal of the American College of Surgeons","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Thomas Burford in Shaping Tobacco Litigation in the 20th Century. 托马斯·伯福德在塑造20世纪烟草诉讼中的作用。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-05 DOI: 10.1097/XCS.0000000000001436

Hannah S Lee, Divyansh Agarwal

引用次数: 0

Enhancing Surgical Oncology Training: Bridging the Gap Between Trainee Competence and Supervision. 加强肿瘤外科培训：弥合实习生能力与监督之间的差距。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI: 10.1097/XCS.0000000000001261

Rohan Kapoor, M D Ray

引用次数: 0

Proceedings of the American College of Surgeons Surgical Adhesions Improvement Project Summit. 美国外科医师学会外科粘连改善项目峰会论文集。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI: 10.1097/XCS.0000000000001358

Samuel Carmichael, David Wiseman, Deshka Foster, Eric Appel, Jessica Cardenas, Joel Zindel, Melinda Maggard-Gibbons, Richard Pg Ten Broek, Rudy Leon De Wilde, Steven Bauer, Steven Mutsaers, Tara Russell, Tess C Huy, Timothy Donahue, Walter Koltun, Yuval Rinkevich, Clifford Y Ko

引用次数: 0

Increased Systemic Immune-Inflammatory Index and Association with Occult Nodal Disease in Non-Small Cell Lung Cancer. 非小细胞肺癌患者全身免疫炎症指数增高与隐蔽性淋巴结疾病的关系

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI: 10.1097/XCS.0000000000001244

Arsalan A Khan, Savan K Shah, Sanjib Basu, Gillian C Alex, Nicole M Geissen, Michael J Liptay, Christopher W Seder

{"title":"Increased Systemic Immune-Inflammatory Index and Association with Occult Nodal Disease in Non-Small Cell Lung Cancer.","authors":"Arsalan A Khan, Savan K Shah, Sanjib Basu, Gillian C Alex, Nicole M Geissen, Michael J Liptay, Christopher W Seder","doi":"10.1097/XCS.0000000000001244","DOIUrl":"10.1097/XCS.0000000000001244","url":null,"abstract":"Background: It has been proposed that more aggressive tumors trigger a stronger inflammatory response than less aggressive types. We hypothesize that systemic immune-inflammatory index (SII) is associated with occult nodal disease (OND) in clinically node-negative patients undergoing lung resection for non-small cell lung cancer (NSCLC).Study design: The study included patients who underwent lung resection with nodal dissection, according to current guidelines, at a single center between 2010 and 2021 for NSCLC. Preoperative SII within 3 weeks of surgery was calculated. OND was defined as a clinically node-negative patient found to be pathologically node-positive. Cut-point analysis for SII was performed to identify the level most strongly associated with OND. Univariable and multivariable logistic regressions were used to examine the association between SII, clinical factors, and OND.Results: A total of 199 patients met inclusion criteria, of whom 51% (102 of 199) were women. The median number of nodes and nodal stations examined was 13 (interquartile range 9 to 17) and 6 (interquartile range 5 to 6), respectively. The cut point was determined to be SII 112 or more. On univariable analysis, high SII was associated with OND (odds ratio 15.75, 95% CI 2.09 to 118.73, p = 0.007). On multivariable analysis, after controlling for age, BMI, approach, sex, smoking history (pack-years), forced expiratory volume in 1 second, performance status, comorbidity, histology, lymphovascular invasion, tumor differentiation, and tumor size, high SII was associated with OND (odds ratio 34.59, 95% CI 2.69 to 444.88, p = 0.007).Conclusions: Increased SII is associated with OND in patients undergoing lung resection for NSCLC.","PeriodicalId":17140,"journal":{"name":"Journal of the American College of Surgeons","volume":" ","pages":"784-795"},"PeriodicalIF":3.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Authenticity in Protecting Against Burnout, Suicide, and Depression Among Surgeons and the Need for Targeted Intervention: In Reply to Kapoor and Ray. 在外科医生中，真实性在防止倦怠、自杀和抑郁中的作用以及有针对性干预的必要性（回复Kapoor及其同事）。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI: 10.1097/XCS.0000000000001268

Kyle M Ockerman, Sarah Sorice-Virk, Jessica Ching

引用次数: 0

Correction. 修正2025年5月。

IF 3.8 2区医学

Journal of the American College of Surgeons Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI: 10.1097/XCS.0000000000001265

引用次数: 0