Journal of Shahid Sadoughi University of Medical Sciences最新文献

筛选
英文 中文
Epidemiological Investigation and Endoscopic Findings in Children Under 14 Years of Age with Foreign Body Ingestion Referred to Yazd Shahid Sadoughi Hospital in Yazd City 转诊至亚兹德市 Shahid Sadoughi 医院的 14 岁以下异物摄入儿童的流行病学调查和内窥镜检查结果
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-03-28 DOI: 10.18502/ssu.v32i1.15229
Roohollah Edalatkhah, Majid Aflatoonian
{"title":"Epidemiological Investigation and Endoscopic Findings in Children Under 14 Years of Age with Foreign Body Ingestion Referred to Yazd Shahid Sadoughi Hospital in Yazd City","authors":"Roohollah Edalatkhah, Majid Aflatoonian","doi":"10.18502/ssu.v32i1.15229","DOIUrl":"https://doi.org/10.18502/ssu.v32i1.15229","url":null,"abstract":"Introduction: Foreign body ingestion is a relatively common and sometimes life-threatening problem. This study was conducted with the aim of investigating the types of foreign body and endoscopic findings in children under 14 years old in Yazd Shahid Sadoughi Hospital in Yazd City. \u0000Methods: This descriptive-cross-sectional study was conducted on 50 children under 14 years of age who referred to the Pediatric Emergency Department of Shahid Sadoughi Hospital with foreign body ingestion in 2018. Demographic information, clinical symptoms, type of foreign body, time interval between ingestion and referral, time interval between the time of referral to endoscopy and findings during endoscopy were collected and analyzed with SPSS version 16. \u0000Results: The average age of the children was 37.14 ± 39.10 months. Out of the 50 children investigated, 33 (66%) were boys and 17 (34%) were girls. The most common clinical symptom was asymptomatic with a frequency of 42%, the most common foreign body was coin (24%), the most common age range was 1-5 years (48%), the most common lesion in endoscopy was the absence of a lesion (56%) and The most common location of the object in endoscopy was stomach (50%) . No statistically significant difference was found between the frequency distribution of endoscopic findings (type of lesion and location of lesion) according to the variables: age, sex and type of foreign body in the investigated children (p>0.05). \u0000Conclusion: The probability of foreign body ingestion is higher in boys and the children aged 1-5 years, so more attention should be paid to these children. Most cases of ingestion of foreign bodies are asymptomatic, but due to serious complications, diagnostic measures should not be postponed.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"118 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the important proteins in causing West Nile virus infection in retinal pigment cells 研究导致视网膜色素细胞感染西尼罗河病毒的重要蛋白质
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-03-28 DOI: 10.18502/ssu.v32i1.15231
Reza Hosseinzadeh, Mahnaz Mohammadi, Saba Taheri
{"title":"Investigating the important proteins in causing West Nile virus infection in retinal pigment cells","authors":"Reza Hosseinzadeh, Mahnaz Mohammadi, Saba Taheri","doi":"10.18502/ssu.v32i1.15231","DOIUrl":"https://doi.org/10.18502/ssu.v32i1.15231","url":null,"abstract":"Introduction: West Nile virus is an infection transmitted through blood-sucking arthropods. Ocular manifestations are one of the characteristics of West Nile virus infection. They occur mostly in connection with severe neurological disease. In this study، using bioinformatics analysis، we investigated and identified the genes in the pathways related to West Nile virus infection in the retina. \u0000Methods: In this study, using bioinformatics methods and referring to the GEO dataset, the appropriate dataset was selected for analysis. This dataset included gene expression profiles in West Nile virus infection with retinal pigment cells. Gene clusters with high and low expression were categorized. For more accurate data evaluation,  databases such as Enrichr، STRING and Network analyst were used. The candidate genes were isolated and their protein relationship was also measured using cytoescape software version 3.7.1. The obtained values with P-Value˂0.05 were selected as significant data. \u0000Results: The number of 830 genes with high expression and 500 genes with low expression was involved in the development pathways of West Nile virus infection in the eye. Apoptosis، necroptosis، AMPK and MAPK autophagy pathways were clearly observed. After evaluating the relationship between protein networks، RIPK1، STAT1/3 and JAK2 increased expression and GSK3B، MAPK8 and TSC2 genes had decreased expression. \u0000Conclusion: The present study showed that important proteins and genes played a major role in strengthening West Nile virus inflammation in the retina, among which RIPK1,TSC2, STAT1 and JAK2 showed a more prominent role in this pathway.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"98 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating of Knowledge of Dentists in Relation to Causes, Symptoms and Treatment of Xerostomia in Yazd City in 2022-2023 评估 2022-2023 年亚兹德市牙医对口腔干燥症的病因、症状和治疗的了解程度
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-03-28 DOI: 10.18502/ssu.v32i1.15232
Yasaman Sabaghzadegan, Zahra Roustaeizade Shooroki, Fatemeh Nadi
{"title":"Evaluating of Knowledge of Dentists in Relation to Causes, Symptoms and Treatment of Xerostomia in Yazd City in 2022-2023","authors":"Yasaman Sabaghzadegan, Zahra Roustaeizade Shooroki, Fatemeh Nadi","doi":"10.18502/ssu.v32i1.15232","DOIUrl":"https://doi.org/10.18502/ssu.v32i1.15232","url":null,"abstract":"Introduction: Saliva has a key role in protecting the oral environment and functions such as chewing, swallowing, lack of saliva can cause many problems and suffering for patients and affect people's quality of life. Therefore, the purpose of this study was to investigate the level of awareness of dentists in Yazd City regarding the causes and symptoms and how to treat dry mouth in 2022-2023. \u0000Methods: In this cross-sectional descriptive study, 125 dentists of Yazd City were selected by convenience sampling method. A valid and reliable questionnaire was designed. The data were analyzed using t-test and ANOVA statistical tests and SPSS V.16. \u0000Results: This cross-sectional study was conducted on 125 dentists in Yazd City; they were selected by convenience sampling method, 65 of them were male (51.2%) and 60 were female (48.8%). The average of age, work experience and knowledge score of the examined dentists were 33.46±7.27, 6.79±6.57 and 15.24±2.90, respectively. There was no statistically significant relationship between knowledge score and gender and work experience and participate in retraining with P = 0.323, P = 0.120 and P = 0.167, respectively. But there was a statistically significant relationship between the knowledge score and age and university of study with P = 0.030 and P = 0.034. People with older age and educated in type 1 university had more knowledge about dry mouth. \u0000Conclusion: The results showed that the dentists of Yazd City had average knowledge about the causes, symptoms and how to treat xerostomia. And it is necessary to cooperate in holding refresher courses in this field.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"97 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological Roles of Fibroblast-Like Synoviocyte Cells in Rheumatoid Arthritis 类风湿关节炎中成纤维滑膜细胞的免疫学作用
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-03-28 DOI: 10.18502/ssu.v32i1.15225
M. Royaei, M. Tahoori
{"title":"Immunological Roles of Fibroblast-Like Synoviocyte Cells in Rheumatoid Arthritis","authors":"M. Royaei, M. Tahoori","doi":"10.18502/ssu.v32i1.15225","DOIUrl":"https://doi.org/10.18502/ssu.v32i1.15225","url":null,"abstract":"Introduction: Fibroblast-like synoviocytes (FLS), also known as synovial fibroblasts or type B synoviocytes, are the primary cells responsible for the structure of the synovial lining. They are crucial for the formation of a healthy, organized synovial lining. In rheumatic synovium affected by inflammation, the typical three-layered synovial lining transforms into a pannus-like structure. Various pro-inflammatory conditions in the joints of rheumatoid arthritis (RA) patients, characterized by elevated levels of cytokines, growth factors, and infiltration of inflammatory cells, strongly activate FLS cells. Moreover, environmental conditions in the joints of RA patients, such as high pressure and hypoxia, induce changes that further contribute to FLS activation and the development of aggressive characteristics. These changes include increased proliferation, reduced apoptosis, and enhanced cell migration, collectively referred to as a tumor-like phenotype. Additionally, FLS cells release inflammatory cytokines, amplifying inflammation and attracting immune cells to the joint. They also play a role in degrading the extracellular matrix and causing cartilage and bone damage through the production of enzymes like matrix metalloproteinases (MMPs), collagenase, aggrecans, and cathepsins. Recent therapeutic approaches have been directed at targeting the signaling pathways that activate FLS cells and inhibiting factors and cytokines produced by these cells to alleviate inflammatory symptoms and reduce joint damage. It is anticipated that these treatment strategies will complement existing therapies in the near future. \u0000Conclusion: FLS cells are the main components of maintaining the health and nutrition of joints. These cells produce various cytokines, chemokines, angiogenic factors, as well as factors that contribute to the breakdown of matrix and cartilage. The main drivers of significant changes in inflamed joints are proliferation and resistance to apoptosis. Treatment strategies have been developed to target the signaling pathways that activate these cells, with a focus on improving inflammatory symptoms. It is expected that these treatment strategies will be incorporated into existing therapies in the near future.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"142 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140369194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effect of Eight Weeks Aerobic and Combined Exercise on Some Hemodynamic Indicators in Middle-Aged Male Patients Undergoing Coronary Artery Bypass Graft Surgery 比较八周有氧运动和联合运动对接受冠状动脉旁路移植手术的中年男性患者的一些血流动力学指标的影响
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14980
Peyman Kaikhosro Doulatyari, Sedigheh Hosseinpour Delavar, M. Ghahramani, Mohammad Rouzbahani
{"title":"Comparison of the Effect of Eight Weeks Aerobic and Combined Exercise on Some Hemodynamic Indicators in Middle-Aged Male Patients Undergoing Coronary Artery Bypass Graft Surgery","authors":"Peyman Kaikhosro Doulatyari, Sedigheh Hosseinpour Delavar, M. Ghahramani, Mohammad Rouzbahani","doi":"10.18502/ssu.v31i12.14980","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14980","url":null,"abstract":"Introduction: Exercise training by modulating blood pressure and heart rate have a protective role for middle-aged cardiac patients. Aim of this study was to compare the effect of eight weeks of aerobic and combined exercise on some hemodynamic indicators in middle-aged male patients undergoing coronary artery bypass graft surgery. \u0000Methods: In this clinical trial, a sample of 30 middle-aged men who underwent coronary artery surgery in 2023 were enrolled after meeting predetermined eligibility criteria and randomized for participation. They were divided into three aerobic (n=10), combined (n=10) and control (n=10) groups. The individuals of the 2 intervention groups performed selected aerobic and combined exercises (with an intensity of 55 - 75% of the maximum heart rate, for 60 minutes) for 8 weeks, 3 sessions per week. Blood pressure, heart rate and peripheral oxygen saturation (SpO2) were measured before and after the intervention. The parametric paired sample t-test, one-way ANOVA test and Tukey's Test were used to examine differences at a significance level of P ≤ 0.05. \u0000Results: The effect of aerobic exercises on systolic blood pressure (P=0.036), diastolic blood pressure (P=0.040) and heart rate (P=0.013) was significant and caused a decrease in these indicators, but the decrease in the combined group was not significant (P>0.05). The intergroup effect difference was not significant (P>0.05). In both aerobic (P=0.000) and combined (P=0.007) groups, the peripheral oxygen saturation has increased significantly and intergroup mean difference was significant (P=0.004). \u0000Conclusion: It seems that aerobic and combined exercises as a helpful intervention strategy to improve hemodynamic indicators, make the patient more adaptable to the conditions after coronary artery bypass graft surgery.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140433937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Causes of Familial Adenomatous Polyposis (FAP), Risk Factors and Clinical Outcomes 家族性腺瘤性息肉病 (FAP) 的遗传原因、风险因素和临床结果
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14974
Mohammad Mehdi Heidari, Elham Afkhami Aqhda, Maryam Tahmasebi, Mehri Khatami, Zahra Shaker Ardakani
{"title":"Genetic Causes of Familial Adenomatous Polyposis (FAP), Risk Factors and Clinical Outcomes","authors":"Mohammad Mehdi Heidari, Elham Afkhami Aqhda, Maryam Tahmasebi, Mehri Khatami, Zahra Shaker Ardakani","doi":"10.18502/ssu.v31i12.14974","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14974","url":null,"abstract":"Introduction: Familial adenomatous polyposis (FAP) is a hereditary disorder that is the most common colon cancer syndrome in an autosomal dominant form. At first, germline mutations in the APC gene (adenomatous polyposis) were identified as the main genetic factor causing FAP, but during subsequent studies, the human MutY (MYH) gene with an autosomal recessive pattern was also identified as the factor causing this disease, which is commonly referred to as MutYH-dependent apoptosis (MAP). FAP and MAP present with an early onset of hundreds of adenomatous polyps in the colon, at a median age of 35–40 years, and are associated with a significantly increased risk of colon cancer (CRC). In some other patients, gastrointestinal polyps, congenital hypertrophy in the retinal pigment epithelium, desmid tumors, and extracolonic malignancies are seen. The common treatment method in patients is through endoscopic and surgical methods. However, the patients with FAP and their relatives should receive appropriate genetic counseling. The purpose of this review article was to describe and investigate the clinical aspects and genetic diseases of FAP and MAP. For this purpose, the latest articles related to FAP genetic disease were selected by searching Google Scholar and PubMed sources. \u0000Conclusion: Despite the progress made in discovering the molecular mechanisms of FAP, its genetic factors are still not fully understood. A deeper understanding of the molecular biology and genetics of this disease can lead to healthy therapies that can be used to rezone intestinal polyps and neoplastic malignancies and be a new target for future treatment. \u0000 ","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"54 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140434259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Service Innovation and its Quality on Patients' Satisfaction and Loyalty during the Covid-19 Pandemic 服务创新及其质量对 Covid-19 大流行期间患者满意度和忠诚度的影响
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14977
HamidReza Golzarfar, Faeze Shirsalimian, Samaneh Norani-Azad
{"title":"Impact of Service Innovation and its Quality on Patients' Satisfaction and Loyalty during the Covid-19 Pandemic","authors":"HamidReza Golzarfar, Faeze Shirsalimian, Samaneh Norani-Azad","doi":"10.18502/ssu.v31i12.14977","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14977","url":null,"abstract":"Introduction: In today's societies, the health sector is growing rapidly, and hospitals, as institutions that provide health and survival of the society and provide health services, have experienced many changes over time.  People have understood that health is a valuable service for their lives, especially when the spread of new diseases threatens the life and health of society. Therefore, the main goal of this research was to investigate the relationship between innovation and service quality on customer satisfaction and loyalty during the Covid-19 pandemic. \u0000Methods: The present research has focused on the impact of service innovation and its quality on patients' satisfaction and loyalty during the Covid-19 pandemic in Yazd Shahid Sadoughi Hospital. The statistical population of the present study was the patients admitted to Shahid Sadoughi Hospital in Yazd, Iran. Because the size of the population was uncertain, Cochran's formula was used to calculate the number of samples, which resulted in 384 people. SPSS and Smart PLS3 software were also used for data analysis. \u0000Results: Among the patients with corona virus, service innovation had a positive and significant effect on the patient satisfaction and 0.11 (p<0.05) on loyalty, respectively. Likewise, service quality has affected the satisfaction and loyalty of the patients by 0.77 and 0.45 with (P<0.05); the effect of the patient satisfaction on loyalty was positive and significant at the rate of 0.41 (P<0.05). \u0000Conclusion: The results have shown that the relationship between service innovation and its quality had a positive and significant effect on patients' satisfaction and loyalty during the Covid-19 pandemic. The reason is that if the quality of the services provided is in accordance with the expectations of the patients, it will cause the satisfaction of the patients and will lead to their loyalty.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140434298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling the Interaction between the Isoniazid Anti-Tuberculosis Drug and Functionalized Carbon Nanotubes for Medical Applications: A Quantum Chemical Study 建立异烟肼抗结核药物与功能化碳纳米管在医疗应用中的相互作用模型:量子化学研究
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14976
Mohadese Moradi, S. Hamedani
{"title":"Modeling the Interaction between the Isoniazid Anti-Tuberculosis Drug and Functionalized Carbon Nanotubes for Medical Applications: A Quantum Chemical Study","authors":"Mohadese Moradi, S. Hamedani","doi":"10.18502/ssu.v31i12.14976","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14976","url":null,"abstract":"Introduction: The purpose of using nano-carriers for drugs delivery, such as nanotubes, was slow release of drug and reducing side effects of drugs. Drugs are very active due to their many functional groups. Therefore, reactivity of drug is reduced by being in nanotube field due to electronic resonance of drug with nanotube and it stays longer in body. The present study aimed to investigate the interaction of isoniazid with functionalized single-walled carbon nanotubes. \u0000Methods: In the present theoretical study, considering the importance of isoniazid as the first line of treatment for tuberculosis disease, the performance of carbon nanostructures for adsorption of isoniazid was evaluated using quantum computation. Using density functional theory at theoretical level of B3LYP/6-31G** structure of drug and f-SWCNT and nano-drug complexes were optimized. \u0000Results: Effect of adsorption on the electronic properties and stability of the nanotube was also examined. In this regard, for different configurations, the strength and nature of intermolecular interactions were evaluated by energy parameters and molecular orbitals. Based on the obtained results, a specific configuration displayed the most negative adsorption energy and enthalpy, establishing itself as the most stable structure among the various configurations. \u0000Conclusion: Results showed that the electron density of the HOMO (Highest Occupied Molecular Orbital) was localized on the nanotube, while the electron density of the LUMO (Lowest Unoccupied Molecular Orbital) was situated on the drug molecule. The energy gap between two molecular orbitals increased due to the adsorption process; changes lead to an increase in the electrical conductivity of the complex following adsorption. According to the natural bond orbitals, results, the isoniazid molecule and functionalized single-walled carbon nanotube act as both electron donor and acceptor in the complex. Analysis of the results obtained from quantum theory of atoms in molecules, showed the intermolecular interaction between the drug and the functional group of the nanotube has been established, the most important of which is the hydrogen bond. Finally, the findings showed that functionalized SWCNTs can be acted as a drug carrier for isoniazid anti-tuberculosis drug. \u0000 ","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"42 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Implantation Failure from an Immunological Point of View 从免疫学角度看复发性植入失败
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14975
Soolmaz Habibi, Parisa Mostafaei, Fariba Ramezanali, Elham Amirchaghmaghi
{"title":"Recurrent Implantation Failure from an Immunological Point of View","authors":"Soolmaz Habibi, Parisa Mostafaei, Fariba Ramezanali, Elham Amirchaghmaghi","doi":"10.18502/ssu.v31i12.14975","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14975","url":null,"abstract":"Introduction: Repeated implantation failure (RIF) is one of the main challenges in modern infertility treatments. Although assisted reproductive technology (ART) has undergone a lot of progression over the last recent years, some women still experience implantation failure after several embryo transfers (ET). Disruption of the mother's immunologic tolerance towards the fetus is one of the risk factors that increases the possibility of rejection the semi-allogeneic embryo by the mother’s immune system and causes failure of embryo implantation. Studies have shown that immunomodulatory treatment approaches, if used in a timely and appropriate manner, have promising results in improving pregnancy outcomes and live birth rates in this group of women. This review focuses on changes in the immune system and the use of immunomodulatory treatments in women with recurrent implantation failure. \u0000Conclusion: It seems that the appropriate use of immunologic tests and proper immunomodulatory treatments can manage IVF failure after repeated embryo transfers.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"37 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designing the Empowerment Model of Patients Hospitalized in the Hospitals Affiliated to Shahid Sadoughi University of Medical Sciences, Yazd 设计亚兹德沙希德-萨多菲医科大学附属医院住院病人的赋权模式
Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2024-02-24 DOI: 10.18502/ssu.v31i12.14979
Safar Ali Dehghani Shoraki, S. Hessam, Roya Biabani Khankahdani
{"title":"Designing the Empowerment Model of Patients Hospitalized in the Hospitals Affiliated to Shahid Sadoughi University of Medical Sciences, Yazd","authors":"Safar Ali Dehghani Shoraki, S. Hessam, Roya Biabani Khankahdani","doi":"10.18502/ssu.v31i12.14979","DOIUrl":"https://doi.org/10.18502/ssu.v31i12.14979","url":null,"abstract":"Introduction: Identifying factors that influence the patient experience are critical to implementing strategies that support patient engagement and ultimately achieve better health outcomes. The present study was conducted with the aim of presenting a model of empowerment of hospitalized patients. \u0000Methods: The current research was a qualitative-quantitative study that was cross-sectional by stratified sampling method with proper allocation in hospitals affiliated to Shahid Sadoughi University of Medical Sciences, Yazd, Iran, on 230 heads, managers, matrons, supervisors, heads of clinical and paraclinical departments and hospital headquarters units, nurses and doctors were done. The data were collected using the demographic information tool and the questionnaire made by the researcher to design a model of empowering patients admitted to the hospital. Determining the ability of the designed model by fitting the data was done with the confirmatory factor analysis method. Data were analyzed by SPSS version 16 software and Amos.v 24 software. \u0000Results: Questionnaire for designing a model of empowering patients in the hospital has 8 areas and 61 items or components. In the present study, the Chi-square ratio to the degree of freedom was significant (p<0.001), which indicated the appropriate fit of the model. The value of the GFI index was estimated at 0.93, which indicated that the model fits well. The values of GFI and AGFI for the empowerment model of hospitalized patients were higher than 0.8. \u0000Conclusion: Organizations and medical institutions have the opportunity to utilize this model to empower patients. The universities of medical sciences and affiliated hospitals should create an enabling environment for enhancing patient empowerment.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信